Portugal Vs Spain Odds, Tips & Best Bets Ahead Of Iberian Showdown

As the 2026 FIFA World Cup knockout stage continues, here are our Portugal vs Spain odds, betting tips and best bets ahead of Monday night's blockbuster Last 16 encounter.

Two of Europe's footballing heavyweights meet for a place in the quarter-finals, with both nations beginning to find their best form at exactly the right time.

Portugal booked their place in the Last 16 after edging past Croatia in dramatic circumstances.

Roberto Martinez's side looked set for extra time after Croatia found a stoppage-time equaliser, only for the goal to be ruled out for offside following a lengthy VAR review.

Portugal held on for a 2-1 victory, but the controversial finish ensured their progression came with plenty of late drama.

The latest Portugal World Cup Odds still place them among the leading contenders, although they now face arguably their toughest test of the tournament so far.

Spain, meanwhile, continued their impressive march through the knockout stages with a commanding 3-0 victory over Austria.

Having steadily improved throughout the competition, Luis de la Fuente's side now appear to be hitting top form at exactly the right moment.

Their combination of patient possession, defensive discipline and clinical finishing has made them one of the most complete teams left in the tournament.

Those performances have seen the latest Spain World Cup Odds shorten significantly, with many expecting La Roja to challenge strongly for the trophy.

The broader World Cup Odds also continue to place Spain among the favourites with most UK Betting Sites, although Portugal possess enough quality to make this one of the standout ties of the round.

Portugal vs Spain Prediction

This promises to be one of the highest-quality matches of the Last 16.

Spain have looked increasingly dominant as the tournament has progressed, controlling matches through possession while creating chances from a variety of attacking areas.

Their convincing victory over Austria was another reminder of the depth and balance throughout the squad.

Portugal, however, remain capable of matching any side on their day.

Despite needing some late fortune against Croatia, they possess outstanding technical quality across the pitch and enough attacking talent to trouble Spain's defence.

Cristiano Ronaldo continues to command attention in the penalty area, while Portugal's attacking options remain among the strongest in the competition.

The veteran forward also remains a threat, and is always capable of delivering on the biggest stage.

Portugal should create opportunities of their own, but Spain's cohesion, confidence and control in midfield could ultimately prove decisive over 90 minutes.

Predicted score: Portugal 1-2 Spain

Portugal vs Spain Betting Tips & Best Bets

Below, we have picked out three of our best Portugal vs Spain bets, which can be backed ahead of Monday night's Last 16 clash.

All odds taken from Betnero at 09:00 UK time on Monday, 6 July 2026.

Spain To Win & Both Teams To Score – 3.60

First up, we are backing Spain to progress while conceding along the way.

Spain have been one of the tournament's standout performers and should enjoy plenty of possession, but Portugal possess enough attacking quality to find the net against any defence.

With Spain expected to edge the contest while Portugal contribute going forward, this combination offers excellent value.

Mikel Oyarzabal Anytime Goalscorer – 2.40

Our anytime goalscorer selection is Mikel Oyarzabal.

The Spanish forward has become an increasingly influential figure as the tournament has progressed, combining intelligent movement with composed finishing inside the penalty area.

Spain are creating chances consistently, and Oyarzabal looks well placed to add to his four-goal tally in what should be another strong attacking performance from La Roja.

Over 3.5 Bookings – 2.28

Finally, we are backing over 3.5 total bookings.

Knockout football often brings a physical edge, and this fixture has all the ingredients of a fiercely contested battle between two fierce rivals.

With both sides competing for a place in the quarter-finals, tactical fouls, intense midfield duels and late-game pressure should provide plenty of opportunities for the referee to reach for his cards.

At odds of 2.28, backing over 3.5 bookings looks an appealing way to round off Monday night's selections.