England vs. Spain Prediction, Odds & Tips: Spain to Inflict More England Woes

Written By James Capps | Published at September 26, 2026
Spain celebrates their win after the FIFA World Cup Final game at MetLife Stadium, Jul 19, 2026, East Rutherford, NJ, USA.

Making an England vs Spain prediction is always tough work. The two sides have been evenly matched for a while now, and Saturday’s encounter at Wembley is the first meeting since the Spaniards came out on top in the final of the Euro 2024 Championships.

England vs. Spain Odds 

Despite home advantage, England will go into this one as underdogs at 37/20, with 10Bet making world champions Spain the 132/100 favourites and going 49/20 on the draw.

With so much quality on show, it’s easy to see why bookmakers are reluctant to commit too heavily to any of the most popular markets. There’s no denying the attacking talent on both sides, but it could well end up being a cagey, tactical affair with very little in it.

To stay up to date on the best odds and sporting lines, keep an eye on our odds page.

James’s England vs. Spain predictions can be backed at 10Betand odds are correct as of 9am on Saturday, 26 September.

One defeat in eight World Cup games was a solid – albeit ultimately unsuccessful – showing from the Three Lions, but they only shone in spells during an up-and-down tournament in the USA:

A 6-4 thumping of France in the Bronze Medal Match should give England fans hope that they can mix it with the best in the world, but they desperately need to address a patchy defensive record that leaves them vulnerable against top sides.

This will be Spain’s first match since lifting their second World Cup, so it’s no surprise that they have an unblemished formbook:

With stats like those behind them, it’s no surprise that they find themselves favourites here, despite tough opposition and one of the toughest stadiums to visit.

England vs. Spain Prediction: Spain to Win and Both Teams to Score @ 16/5

With Spain arriving in imperious form and England suffering several squad withdrawals, I like the look of the world champions coming out on top.

Victory here in 2018 means this crop will arrive at Wembley with no fear, as well as a number of Premier League players who know how this England side tick.

The hosts have an excellent home record, but it has predominantly come against weaker opposition, and after a turbulent World Cup, Thomas Tuchel’s men are there for the taking.

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