Arsenal vs Atletico: Champions League Betting Tips & Best Bets

The UEFA Champions League semi-finals enter the second leg this week, and so here are our best Arsenal vs Atletico betting tips and predictions ahead of Tuesday's huge clash in North London.

Arsenal head back to the Emirates after a 1-1 draw against Atletico in Madrid. Viktor Gyokeres and Julian Alvarez exchanged penalties on either side of half-time, meaning their sides enter the second leg at the Emirates all-square.

Mikel Arteta's Gunners would likely have taken a draw had they been offered it before the game. Arsenal thrashed Atletico 4-0 in October, and will fancy themselves again on home turf.

Atletico and Diego Simeone may feel they missed an opportunity last week, but there is still all to play for.

Neither of these two sides has ever won the Champions League, with Arsenal's last final 20 years ago.

It's been 10 years since Atletico last made the final, having lost in both 2014 and 2016 to arch rivals, Real Madrid.

This one should be a thrilling, nervous and tense battle. Both sides are just one game away from their first final in this competition for at least a decade.

The promise of another crack at Europe's biggest prize awaits.

Odds taken from Betnero at 11:00 UK time, on Tuesday, 5 May 2026.

Arsenal vs Atletico Prediction

Ahead of Tuesday's game, Arsenal are the overwhelming favourites with most UK betting sites. The Gunners are priced at around 1.58, while Atletico are 5.50 underdogs.

Having already beaten Atletico at the Emirates once this season, Arteta's side have every right to be full of confidence.

But nerves can play a big role at this stage of the competition, and Arsenal have shown some mental fragility in big games.

We do believe home advantage should be enough for the Premier League outfit, but it won't be easy.

An early goal might settle Arsenal's nerves, but scoring too early can bring its own problems. If the Gunners sit back and try to defend a lead, they may invite pressure and allow Atletico back into the match.

Our Prediction: Arsenal 2-1

Arsenal vs Atletico Betting Tips

Below, we have picked out three of our best Atletico vs Arsenal betting tips that you can back ahead of Wednesday's game at the Riyadh Air Metropolitano.

Arsenal & Both Teams To Score - 3.40

For our first tip, we are backing Arsenal to get the job done, but not to keep a clean sheet.

The Gunners will be favourites on home soil, and should have enough to take the win.

However, Atletico have shown they are more than capable of hurting Arsenal, and will be looking to avenge the heavy loss from earlier this season.

Arsenal To Win On Penalties - 16.00

Next up, we feel there is a strong chance this one goes to penalties.

If Atletico can frustrate and irritate Arsenal, and Simeone's tactics can shut Arsenal out, we could be in for a tight and cagey affair.

The visitors will likely tighten up away from home and look to take the contest all the way to a shootout.

However, Atletico's recent penalty record is just one win from their past five shootouts. Arsenal, meanwhile, have won eight of their last 11 when they have been taken to penalties.

And with odds of 16.00, this pick has a huge potential for profit.

A Red Card To Be Shown - 3.70

Finally, we feel there is a strong case to be made for a red card being shown on Tuesday.

Both sides will be nervous, with the tie delicately balanced and all to play for. Tempers and composure will be tested, and all it takes is one rash action or loss of nerve for someone to make a poor challenge or lose their heads.

A red card may well ruin the game, but it could very well happen in this one.