Sweet 16 Odds And Schedule: 2021 NCAA Men’s Basketball Tournament

Written By Matt Burke on March 22, 2021 - Last Updated on March 23, 2021
Sweet 16 schedule odds TV channel start time Sixteen

The 2021 NCAA men’s basketball tournament field has been more than cut in half, with only 16 teams remaining from the original 68. Here we will look at Sweet 16 odds and the Sweet 16 schedule.

Tournament darling Loyola Chicago, which knocked off 1-seed Illinois this past Sunday, is actually favored in its Sweet 16 game by a sizable margin despite its usual underdog status. The sons of Sister Jean are favorites over Oregon State.

The largest Sweet 16 spread is for the Gonzaga versus Creighton game, with the Zags favored by points.

Below are the latest NCAA basketball tournament odds and sportsbook offers.

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Sweet 16 odds

The latest Sweet 16 odds. Here are the games for Saturday, March 27.

Oregon State vs. Loyola Chicago (2:40 p.m. CBS)

Villanova vs. Baylor (5:15 p.m. CBS)

Oral Roberts vs. Arkansas (7:25 p.m. TBS)

Syracuse vs. Houston (9:55 p.m. TBS)


Here are the games for Sunday, March 28.

Creighton vs. Gonzaga (2:10 p.m. CBS)

Florida State vs. Michigan (5 p.m. CBS)

UCLA vs. Alabama (7:15 p.m. TBS)

Oregon vs. USC (9:45 p.m. TBS)


View more college basketball odds at top US sportsbook like DraftKings Sportsbook, FanDuel Sportsbook and BetMGM.

Sweet 16 schedule and betting previews

This year’s NCAA tournament will be quite different, and it’s not just because the entire Big Dance will be played in the state of Indiana. The Sweet 16 schedule will also change for the 2021 tournament as it will be played on different days than usual. In the past, Sweet 16 games were played on Thursday and Friday nights. Now, everything is bumped back two days as the Sweet 16 will take place on Saturday and Sunday, and the Elite 8 will fall on a Monday and Tuesday.

Here is the NCAA basketball tournament Sweet 16 schedule (all times Eastern Standard) with betting previews. Click on the links to get a full wagering breakdown of each game.

Saturday, March 27

Sunday, March 28

TV channel, start time information

NCAA tournament games will once again be broadcast live on several different TV channels: CBS, TBS, TNT and TruTV. You can live stream all the games at NCAA March Madness Live – which is managed by Turner Sports.

Matt Burke Avatar
Written by
Matt Burke

Matt Burke is the Sports Editor and Head of Evergreen/SEO Content at TheLines.com. He is the Founder and former Editor-in-Chief of MetroBet, a digital and print sports betting platform, and was the Executive Sports Editor at Metro US Newspapers (New York, Philadelphia, Boston) from 2014-2020. Matt has covered Super Bowls and Final Fours, and his work has appeared for Sports Illustrated, CBS Sports, the Eagle Tribune, Gloucester Daily Times and Newburyport Daily News. Matt is a graduate of the University of Connecticut.

View all posts by Matt Burke