MLS Best Bets and Picks for Sept. 12: Inter Miami & Nashville Lock Horns

Written By Gareth Hinton | Published at September 12, 2026
Sep 9, 2026; Chicago, Illinois, USA; Inter Miami forward Lionel Messi (10) takes a shot on goal during the second half against Chicago Fire at Soldier Field. Mandatory Credit: Talia Sprague-Imagn Images

With the playoffs not too far away, the MLS action is heating up. We have another huge round of fixtures to look forward to today.

Inter Miami CF and Nashville SC go head-to-head at Nu Stadium in the day's standout MLS match. Also, Sporting Kansas City hosts Los Angeles FC, and New York City FC makes the trip to Real Salt Lake.

Check out the latest odds and MLS best bets in this betting preview.

Inter Miami CF vs Nashville SC MLS Best Bets: Honours Even in Florida

The Eastern Conference’s top two lock horns in Florida tonight, as Inter Miami takes on Nashville. Miami will close the gap at the summit to just six points with a home win, but an away victory would take the Coyotes a step closer to the Supporters’ Shield.

Inter Miami has been inconsistent of late, winning just one of its last seven MLS games. The Herons have drawn their last two, tying 1-1 away at Chicago Fire last time out.

Nashville is enjoying an exceptional season, collecting an incredible 53 points after 16 wins, five draws, and just three defeats. However, B. J. Callaghan’s troops lost at Toronto FC in midweek, ending a six-game unbeaten run (four wins, two draws).

Nashville is looking to get back to winning ways, but Nu Stadium is a tough place to visit. A draw would be an okay outcome for the leader, and we can see the division’s top two cancelling each other out in Florida.

With that in mind, check out BetMGM’s good MLS soccer odds of +310 for the tie and both teams to score.

Our Prediction: Draw & Both Teams to Score – +310, BetMGM

Sporting Kansas City vs Los Angeles FC MLS Predictions: Kansas’ Winless Woes to Continue

It has been a miserable season for Sporting KC, who props up the Western Conference standings. Later today, Marc Dos Santos’ Los Angeles visits Sporting Park.

Kansas City is the bottom team in the West having only won four MLS games all season. Sporting has taken just one point from its last seven games since claiming a rare victory over Minnesota United in July.

LAFC heads to Kansas unbeaten in four, though three of those have been draws. Still, the Black and Gold Falcons beat New York Red Bulls in midweek and are flying high in third place in the Western Conference.

Sporting KC cannot seem to buy a win, and Los Angeles should take advantage of the home team’s woes in this one. Our money is going on the visitor to be winning at half time and full time at +145.

Our Prediction: Los Angeles FC HT/FT – +145, BetMGM

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Real Salt Lake vs New York City FC Picks: Too Close to Call in Sandy

Real Salt Lake and New York lock horns in an intriguing-looking MLS matchup at America First Field tonight. The teams are in separate divisions, but both have taken 29 points.

Claret and Cobalt have not tasted a victory in MLS since beating Colorado Rapids at home in mid-May. Since then, Real Salt Lake has drawn four and lost six of ten.

New York is also struggling for wins, picking up just two in its last 11 MLS games. City is winless in seven (four draws, three losses), and Pascal Jansen’s boys suffered a 2-1 home defeat to New England Revolution in their previous outing.

Both will be eager to end winless streaks, but the pair are tough to split on paper. The last meeting in 2023 ended goalless, and we can see the evenly matched sides playing out another stalemate in Utah.

We like the look of BetMGM’s +260 for the draw at America First Field.

Our Prediction: Draw – +260, BetMGM

MLS Odds taken from BetMGM at 08:00 ET time, on September 12