SNF Week 6 NFL Parlay Picks: Uncovering Value in Chiefs vs Lions
Written By Nick Crain | Last Updated at October 13, 2025
The NFL Week 6 schedule will be headlined by a highly anticipated Sunday Night Football contest between the Kansas City Chiefs and Detroit Lions. It’s a perfect showcase of two dynamic offenses, two top-tier quarterbacks and a chance for bettors to find value in a variety of markets.
With the Lions red-hot and the Chiefs starting to find rhythm, this primetime matchup offers multiple ways to attack the board, especially if you leverage sportsbook promos. With that in mind, here are the three best SNF parlay picks for Week 6 and where the lines provide an edge for the best odds tonight.
Game Script & Spread
📊 Parlay Odds: +702 (via BetMGM) ⭐
- Leg 1: Lions +2.5 (-110)
- Leg 2: Lions ML +120
- Leg 3: Over 52.5 (-110)
The Lions have been one of the NFL’s most complete teams through the first five weeks of the season, and they enter this one with confidence after multiple statement wins. While it's very difficult to beat the Chiefs in Kansas City, Detroit is the better team and has tremendous value as a betting underdog in this one.
The over is appealing given both offenses’ ability to score in bunches and their quick-strike potential. Taking the Lions with points and moneyline exposure creates correlated upside if this game turns into a shootout. This parlay becomes even more valuable if you leverage BetMGM's bonus codes.
High-Value Player Props
📊 Parlay Odds: +506 (via Caesars Sportsbook) ⭐
- Leg 1: Patrick Mahomes over 0.5 Interceptions (-125)
- Leg 2: Patrick Mahomes longest completion over 38.5 yards (-115)
- Leg 3: Brashard Smith over 21.5 rushing + receiving yards (-125)
Mahomes remains electric, but his aggressiveness has also come with turnover risk. The Lions’ secondary has been opportunistic, making the interception prop an intriguing angle. Mahomes’ arm talent gives him a shot to clear the longest completion line at any time, especially with Detroit likely forcing downfield attempts.
Bet $1, Double your Winnings on your Next 20 Wagers. Up to $25 Max Bet Per Boost Smith’s dual-threat usage in the Chiefs’ offense rounds out this parlay with a volume-driven over. Especially as Kansas City continues to figure out what it has in the backfield and if a potential trade is needed, Smith could get more snaps tonight to see what he can provide with a larger opportunity.
Detroit's TD Duo
📊 Parlay Odds: +214 (via bet365) ⭐
- Leg 1: Jahmyr Gibbs Anytime TD (-155)
- Leg 2: David Montgomery Anytime TD (-110)
The Lions boast one of the NFL’s best backfields, and both running backs have been featured heavily in red zone situations. Gibbs’ versatility gives him multiple paths to score, whether through short receptions or red zone carries, while Montgomery continues to handle goal line work.
Pairing both players in an Anytime TD Scorer combo builds on Detroit’s expected offensive success. This pair of RBs is no stranger to seeing both score in the same game, with another opportunity to do so tonight.
As NFL Week 6 odds continue to shift, the key for bettors is identifying correlated plays that make sense together rather than chasing standalone value. This Lions-Chiefs primetime matchup offers just that — a mix of explosive offenses, star players and potential game flow volatility that favors overs and offensive props.
Whether you’re targeting NFL player props, touchdown markets, or NFL parlay bets, these plays bring both structure and upside. Expect points, big moments, and plenty of fireworks in one of the most anticipated games on the NFL Week 6 schedule.
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