SNF Week 5 NFL Player Props: Uncovering the Hidden Value in Bills vs Patriots Matchup
Written By Nick Crain | Last Updated at October 8, 2025
As the lights come on for Sunday Night Football at Highmark Stadium, the Buffalo Bills will host the New England Patriots in a Week 5 matchup that brings another slate of intriguing NFL player prop bets that carry plenty of value. Between rookie tests, veteran consistency and mismatched defenses, the SNF Week 5 player props board has several smart ways to attack.
Despite the fact that this game could get lopsided quickly, there’s still plenty of value throughout this game. In fact, the fact that this game could become a blowout could make an impact on which players are getting touches late in the contest.
With that in mind, here are the best NFL prop bets for Week 5 of NFL action on Sunday Night Football and where the lines provide an edge.
TreVeyon Henderson Anytime TD Scorer
🏈 Odds (via bet365): +190 💰
Henderson finally found the end zone last week, but his could be the week he’s completely unleashed, especially if this game gets out of hand and the Patriots opt to let him loose. Whether it’s a goal line score or a chunk play, Henderson is capable of producing touchdowns on any given night.
Josh Allen o19.5 Pass Completions
🏈 Odds (via Caesars Sportsbook): -136 💰
The MVP frontrunner has completed 85 passes in four games this season, making this a very achievable target. What it really comes down to is how much he’ll be needed, given Buffalo could build a quick lead and start relying on the ground game, or even give Allen a break late in the game to give a backup QB reps.
Bet $1, Double your Winnings on your Next 20 Wagers. Up to $25 Max Bet Per Boost Drake Maye o0.5 Interceptions
🏈 Odds (via bet365): -115 💰
If New England falls behind in this game, Maye could be forced to throw the ball even more and play desperate. He’s only thrown two picks this season, but this Bills team is one of the best in the entire league and this will be his most difficult game yet.
Dalton Knox o8.5 Receiving Yards
🏈 Odds (via BetMGM): -118 💰
Knox is an inconsistent weapon, but he has earned as many as five targets in a game this season. He could exceed this receiving total with one catch, and if the Bills go up big, then he could earn more reps at TE late in the game to cash on this in the fourth quarter.
That wraps up this week’s look at the SNF Week 5 props odds worth backing. These Week 5 NFL props provide multiple paths to profit. Be sure to monitor injury reports and late line movement before kickoff, as small shifts can create big edges in the best NFL prop bets Week 5.
Featured Image Mandatory Credit - Syndication: Democrat and Chronicle
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