SEC College Football Odds: Week 3 Game Notes, Betting Guide, TV Schedule

SEC football turns its focus to the conference slate this weekend with a packed slate of enticing odds. LSU visits South Carolina, Florida hosts Texas A&M, and Georgia hits the road to play Kentucky in SEC play. In non-conference stints, Alabama visits Wisconsin for one of the weekend's biggest games on tap. Oklahoma hosts Tulane in what could be a tricky matchup and Missouri hosts Boston College in the week's lone ranked matchup.

Let's run down the entire SEC slate this weekend. Below, you'll find the best SEC odds, injuries, weather, and betting notes to help you navigate Week 3.

SEC Football Odds: Week 3

Browse the best odds for SEC football in Week 3 below. Click inside the odds tables to bet now.

No. 4 Alabama at Wisconsin, Saturday (12:00 p.m., FOX)

• Opening odds: BAMA -8.5, O/U 51.5
• Teams have only met twice and split those meetings (Alabama won in 2015, Wisconsin won in 1928)
• Thanks to a 28-point 4th quarter, Alabama swept a struggle against USF under the rug. The Tide only led 14-13 heading in
• 82% of Alabama’s offensive production last week came after replacing its starting RT (moved to Elijah Pritchett)
• Alabama tackle Kadyn Proctor missed last week with a shoulder injury
• Luke Fickell is 4-1 ATS as a home underdog at Cincinnati and Wisconsin
• Kalen DeBoer is 12-2-1 ATS against non-conference opponents (only ATS losses: 2024 National Championship, last week)

Notable injuries: OT Kadyn Proctor (BAMA), RB Tawee Walker (WIS), DT James Thompson (WIS), WR Quincy Burroughs (WIS)

College Football National Title odds

No. 16 LSU at South Carolina, Saturday (12:00 p.m., ABC)

• Opening SEC football odds: LSU -7, O/U 52
• Watch the weather here! Thunderstorms are forecast on Saturday for Columbia with rain from Friday through Wednesday
• LSU leads the all-time series, 19-2, with an average +16.7 average margin of victory
• LSU has not played in Columbia since 2008
• South Carolina is 1-9 (3-7 ATS) in its last 10 SEC home openers
• The Gamecocks managed just 3.6 yards per play in Week 1 against Old Dominion and escaped with a 23-19 win
• Last week, South Carolina (+9.5) thumped Kentucky, 31-6, holding UK to just 183 total yards
• LSU is 0-2 ATS and its only FBS matchup went 20 points under the total (closed 67.5)
• Starting LSU DT Jacobian Guillory is out for the season

Notable injuries: QB LaNorris Sellers (SC), CB Emory Floyd (SC), WR Chris Hilton (LSU), DT Jacobian Guillory (LSU), RB John Emery (LSU), TE Ka'Morreun Pimplieton (LSU)

No. 24 Boston College at No. 6 Missouri, Saturday (12:45 p.m., SEC Network)

• Opening odds: MIZ -16.5, O/U 54
• This is the lone matchup between two ranked teams in Week 3
• Missouri is 10-6-1 ATS during a 17-game non-conference home win streak
• A 56-0 win over FCS Duquesne vaulted Boston College into the Week 3 AP Top 25. They beat a free-falling Florida State in Week 1 on the road, as well
• Missouri is dealing with injuries to three top pass catchers: Luther Burden III (illness, probable), Theo Wease (arm, probable), and Brett Norfleet (shoulder, questionable). Starting guard Cam'Ron Johnson is also questionable
• Watch for Boston College to be overvalued based on two bad opponents!

Notable injuries: WR Luther Burden III (MIZ), WR Theo Wease (MIZ), TE Brett Norfleet (MIZ), OG Cam'Ron Johnson (MIZ), DE Darris Smith (MIZ), DB Cameron Martinez (BC)

Tulane at No. 15 Oklahoma, Saturday (3:30 p.m., ESPN or ESPN2)

• Opening odds: OU -13.5, O/U 49.5
• Watch the weather here! Temperatures Saturday are forecast to be near 100º at kickoff in Norman
• Oklahoma is still dealing with cluster injuries to its wide receiver room, although Nic Anderson practiced this week and should play
• Tulane covered a +9.5 spread last week and nearly beat No. 14 Kansas State, falling 34-27
• A 2021 matchup was supposed to be played in New Orleans, but was moved to Norman due to a hurricane. Tulane (+32) pushed Oklahoma to the brink but lost, 40-35
• Last week, Oklahoma (-27.5) gained less than 250 total yards and escaped with a 16-12 win versus Houston
• QB Jackson Arnold is averaging just 5.5 yards per attempt and is averaging 157.5 yards through his first two games
• WR Deion Burks, who is questionable this week, has accounted for 32% of all targets and three of six touchdowns

Notable injuries: WR Deion Burks (OU), WR Jalil Farooq (OU), WR Jayden Gibson (OU), WR Jaquaize Pettaway (OU), C Branson Hickman (OU), WR Shazz Preston (TUL)

Texas A&M at Florida, Saturday (3:30 p.m., ABC)

• Opening SEC football odds: A&M -3.5, O/U 49.5
• Watch the weather here! Thunderstorms are forecast Saturday and will persist all weekend long, meaning this forecast likely doesn't change much
• All-time series is tied, 3-3
• Both teams began the year 0-2 against the spread with a loss to a ranked opponent at home and a win over an FCS foe
• This is just the second time Texas A&M has visited Florida since joining the SEC
• The Aggies rank 110th in dropback EPA and 112th in rush EPA allowed through two games
• Texas A&M's 3.6 yards per play against Notre Dame ranks 122nd in the country (vs. FBS competition only)
• Five-star plus QB D.J. Lagway threw for over 450 yards against Samford last week (five Big Time Throws on 28 attempts, per PFF)

Notable injuries: C Mark Nabou (A&M), WR Jabre Barber (A&M), WR Reuben Owens (A&M), QB Graham Mertz (UF), WR Khaleil Jackson (UF), SAF Asa Turner (UF), DB Sharif Denson (UF), CB Devin Moore (UF), DL Joey Slackman (UF)

UAB at Arkansas, Saturday (4:15 p.m., SEC Network)

• Opening odds: ARK -21.5, O/U 59.5
• Through two games under OC Bobby Petrino, Arkansas improved from 121st in yards per play (2023) to 28th (6.8)
• Arkansas is 2-0 ATS to begin the year (70-0 win over Arkansas-Pine Bluff, 39-31 double OT loss to Oklahoma State)
• Under Sam Pittman, Arkansas is 12-2 straight up against non-conference opponents
• UAB (-11.5) lost to ULM last week, 32-6, despite allowing just 87 passing yards (-3 turnover margin)

Notable injuries: WR Jaedon Wilson (ARK), RB Rashod Dubinion (ARK), OG Patrick Kutas (ARK)

No. 5 Ole Miss at Wake Forest, Saturday (6:30 p.m., The CW)

• Opening odds: MISS -23, O/U 63.5
• Watch the weather here! Rain and wind (sustained 15+ mph) could be a factor Saturday
• Jaxson Dart leads the nation in passing yards (795) through two games (vs. Furman, Middle Tennessee)
• Wake Forest ranks 105th in dropback EPA through three games
• Star EDGE Jasheen Davis is doubtful to play in this game, a major blow to the pass rush (2.3% sack rate, 100th)
• Lane Kiffin is 7-3-1 ATS as a road favorite at Ole Miss

Notable injuries: WR Jordan Watkins (MISS), OL Jeremy James (MISS), EDGE Jasheen Davis (WF)

Odds to make the College Football Playoff

UTSA at No. 2 Texas, Saturday (7:00 p.m., ESPN)

• Opening odds: TEX -33.5, O/U 53.5
• Watch the weather here! High temperatures are expected near 100º on Saturday
• UTSA plays indoors at the Alamodome, so they are not as acclimated to playing in these temperatures as Texas is
• Texas is 2-0 ATS with a 52-0 win over Colorado State and 31-12 win at Michigan
• UTSA is 0-2 ATS with a 28-16 win over Kennesaw State (-22.5) and a 49-10 loss to Texas State (+2.5)
• UTSA WR De'Corian "J.T." Clark dressed for practice this week. He has not played since suffering a catastrophic knee injury in Nov. 2022

Notable injuries: RB C.J. Baxter (TEX), WR De'Corian Clark (UTSA)

Vanderbilt at Georgia State, Saturday (7:00 p.m., ESPN+)

• Opening odds: VAN -9.5, O/U 46.5
• Watch the weather here! Forecasts call for a complete washout Saturday with thunderstorms from Hurricane Francine expected throughout the entire weekend
• First-ever meeting between these two teams
• Vanderbilt is 2-0 ATS to begin the year with a 34-27 overtime win against Virginia Tech (+13.5) and 55-0 win against FCS Alcorn State (-33.5)
• QB Diego Pavia is 16-4-1 ATS since taking over as the full-time starter of New Mexico State in 2022

Notable injuries: WR Ja'Cyais Credle (GAST), TE Ahmon Green (GAST)

New Mexico at Auburn, Saturday (7:30 p.m., ESPN2 or ESPNU)

• Opening odds: AUB -28.5, O/U 59.5
• Last week, Auburn (-11.5) lost to Cal, 21-14, without the Bears' top player, RB Jadyn Ott
• QB Payton Thorne threw four interceptions in the loss
• New Mexico is 2-0 ATS on the year, averaging 35 points per game
• The Lobos come off a bye week
• New Mexico scored 39 points in its Week 1 loss to Arizona (allowed 11 YPP)
• Since 2020, Auburn is 4-11 ATS against FBS non-conference foes

Notable injuries: WR Cam Coleman (AUB), Izavion Miller (AUB)

Toledo at Mississippi State, Saturday (7:30 p.m., ESPN2 or ESPNU)

• Opening odds: MSST -9.5, O/U 57.5
• First-ever meeting between these teams
• Toledo was out-gained, 384-258, against UMass last weekend but a Jacquez Stewart 98-yard kick return touchdown led Toledo (-19.5) to a 38-23 win
• Mississippi State lost 30-23 at Arizona State. It trailed in time of possession, 40:13-19:47
• The Bulldogs had just eight possessions (excl. one play possession into half) and had three non-scoring drives of less than four plays
• MSST allowed Arizona State to score on its first five possessions

Notable injuries: WR Kelly Akharaiyi (MSST), CB Corey Ellington (MSST), RB Jeffrey Pittman (MSST), K Luke Pawlak (TOL), CB Andre Fuller (TOL)

No. 1 Georgia at Kentucky, Saturday (7:30 p.m., ABC)

• Opening SEC football odds: UGA -23.5 O/U 45.5
• Georgia held its first two opponents to three points apiece (vs. Clemson, Tennessee Tech)
• UGA is 9-6 ATS in its last 15 true road games
• Kentucky (-11.5) was blown out, 31-6, by South Carolina last week
• Brock Vandagriff went just 3/10 for 30 passing yards in the game and was sacked three times on nine pressures
• Under pressure in Week 2, Vandagriff completed one pass for two yards. 75% of that pressure came from the left side of the line

Notable injuries: DE Mykel Williams (UGA), RB Roderick Robinson (UGA), RB Travis Etienne (UGA), TE Oscar Delp (UGA), RT Gerald Mincey (UK), RB Chip Traynum (UK), RB Jamarion Wilcox (UK)

Kent State at No. 7 Tennessee, Saturday (7:45 p.m., SEC Network)

• Opening odds: TEN -47.5, O/U 62.5
• Watch the weather here! Thunderstorms are forecast for Saturday
• When Tennessee is favored by 19+, the over is 11-3 and the Vols are 9-6 ATS
• Kent State (-18) lost outright to FCS St. Francis-PA, 23-17. The Flashes allowed 400 yards of offense
• Just nine of 22 targets to star WR Crishon McCray has been completed this year
• Tennessee allowed just 143 total yards of offense, including 31 on the ground, in a 51-10 blowout of NC State

Notable injuries: SAF Jourdan Thomas (TEN), RB Cameron Seldon (TEN), WR Braylon Staley (TEN), RB Gavin Garcia (KENT)

We are covering much more than SEC football odds this week in college football. Browse some more of our betting coverage below.