Bookmakers are anticipating the San Francisco 49ers to play similarly in 2022, as the team’s over/under is set at 10 wins, which matches the 10 games they won last season.
49ers 2022 Futures and Win Total Betting Odds
See the table below for the latest San Francisco 49ers betting odds. Click on the odds to place your bet!
49ers Total Win/Loss Betting Insights
- Last season the 49ers finished 10-7, qualifying for the playoffs but getting eliminated in the Conference Championship round.
- The Niners are playing the seventh-hardest schedule this season (based on their opponents’ projected win total this year).
- The 49ers posted a 4-4 record at home and were 6-3 on the road last season.
- In the NFC West the 49ers won just two games (2-4), and in the conference as a whole they went 7-5.
- Based on their NFC West opponents’ combined win total last year (60), the Niners have the third-toughest divisional schedule in the league.
- The 49ers participated in four island games last season, and they put up a 1-3 record in those contests.
- The Niners have 10 games this season against teams that went over .500 in 2021. That schedule includes four teams that had 12 or more victories and one squad with five or fewer wins last year.
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49ers 2022 Player Changes
Free Agency and Trades – Additions
| Name | Position | 2021 GP | Former Team |
|---|---|---|---|
| Malik Turner | WR | 14 | Cowboys |
| Ray-Ray McCloud | WR | 16 | Steelers |
| Tyler Kroft | TE | 9 | Jets |
| Marcus Johnson | WR | 7 | Titans |
| Kemoko Turay | DE | 13 | Colts |
| Charvarius Ward | CB | 13 | Chiefs |
| Kerry Hyder | DE | 15 | Seahawks |
| Oren Burks | ILB | 17 | Packers |
| George Odum | FS | 17 | Colts |
| Hassan Ridgeway | DT | 17 | Eagles |
Free Agency and Trades – Losses
| Name | Position | 2021 GP | New Team |
|---|---|---|---|
| Trent Sherfield | WR | 17 | Dolphins |
| Arden Key | DE | 17 | Jaguars |
| Kentavius Street | DT | 17 | Saints |
| D.J. Jones | DT | 17 | Broncos |
| Marcell Harris | LB | 15 | Jets |
| Jaquiski Tartt | S | 14 | Eagles |
| K’Waun Williams | CB | 14 | Broncos |
| Trenton Cannon | RB | 12 | Titans |
NFL Draft Additions
| Name | Pick | Round | Position | College |
|---|---|---|---|---|
| Drake Jackson | 61 | 2 | OLB | USC |
| Tyrion Davis-Price | 93 | 3 | RB | LSU |
| Danny Gray | 105 | 3 | WR | Southern Methodist |
| Spencer Burford | 134 | 4 | OL | Texas-San Antonio |
| Samuel Womack | 172 | 5 | CB | Toledo |
| Nick Zakelj | 187 | 6 | OL | Fordham |
| Kalia Davis | 220 | 6 | DT | Central Florida |
| Tariq Castro-Fields | 221 | 6 | CB | Penn State |
| Brock Purdy | 262 | 7 | QB | Iowa State |
49ers 2022 Opponents and Schedule
| Opponent | Date | Week | Last Meeting |
|---|---|---|---|
| @ Bears | September 11 | 1 | 33-22 SF (10/31/2021) |
| Seahawks | September 18 | 2 | 30-23 SEA (12/5/2021) |
| @ Broncos | September 25 | 3 | 20-14 SF (12/9/2018) |
| Rams | October 3 | 4 | 20-17 LAR (1/30/2022) |
| @ Panthers | October 9 | 5 | 51-13 SF (10/27/2019) |
| @ Falcons | October 16 | 6 | 31-13 SF (12/19/2021) |
| Chiefs | October 23 | 7 | 38-27 KC (9/23/2018) |
| @ Rams | October 30 | 8 | 20-17 LAR (1/30/2022) |
| Chargers | November 13 | 10 | 29-27 LAC (9/30/2018) |
| @ Cardinals | November 21 | 11 | 31-17 ARI (11/7/2021) |
| Saints | November 27 | 12 | 27-13 NO (11/15/2020) |
| Dolphins | December 4 | 13 | 43-17 MIA (10/11/2020) |
| Buccaneers | December 11 | 14 | 31-17 SF (9/8/2019) |
| @ Seahawks | December 15 | 15 | 30-23 SEA (12/5/2021) |
| Commanders | December 24 | 16 | 23-15 WAS (12/13/2020) |
| @ Raiders | January 1 | 17 | 34-3 SF (11/1/2018) |
| Cardinals | January 8 | 18 | 31-17 ARI (11/7/2021) |
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