Saints vs. Panthers MNF Preview: Best NFL Week 2 Betting Site Odds, Promos

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Written By Derek Wagner | Last Updated
saints vs panthers odds

The New Orleans Saints (1-0) visit the Carolina Panthers (0-1) at 7:15 p.m. ET on Monday, Sept. 18. Saints odds show New Orleans is a spread favorite and on the moneyline, with Panthers at as the best price for Panthers to win across sports betting sites. The point total is set at . In this article, we break down everything you need to know before placing a bet on Saints vs. Panthers odds.


NFL Week 2 odds for Monday Night Football are explained below. Know what you’re betting before you bet it. You may click any of the odds in this post to navigate to the sportsbook to place a bet.


Michael Thomas Over Receiving Yards

With no Horn suiting up for the Panthers, I like Thomas to go over his receiving yards in this one. C.J. Henderson will slot in at cornerback for Carolina on Monday night. He was targeted twice in Week 1 and allowed 45 yards.

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The forecast has the temperature settling in at 60 degrees and 5 mph winds at Bank of America Stadium before kickoff. The chance of rain is 58%.


NFL Teams finalize their injury reports two days before a game and denote whether a player is questionable, doubtful, or out. Practice participation is also logged during the week. Here is the Saints injury report, as well as the Panthers injury report for this week.

Starters On The Injury Report

Cornerback Jaycee Horn is expected to miss multiple weeks with a hamstring injury. Receiver DJ Chark is also nursing a hamstring injury suffered last week in practice. He practiced on Friday last week but was ruled out for Week 1. Saints running back Kendre Miller also missed last week’s game with a hamstring. Monitor these closely as the week progresses. The extra day off could benefit Chark and Miller.


The Panthers offensive line graded out as a middle-of-the-road unit after their Week 1 loss to the Falcons and Arthur Smith. However, bettors should take that with a grain of salt, as Atlanta doesn’t possess a star pass rusher. It Carolina faces a bit of an upgrade on Monday with Cam Jordan coming to town.

In recent years, Allen hasn’t shown a desire to blitz at a high rate. But I’d expect a few scenarios Monday night where he dials up the pressure and tries to rattle the rookie QB. Regardless of whether that happens, though, cornerback Marshon Lattimore should be able to lock down his side of the field, as the veteran DB graded out as one of the best corners in man coverage last week. He was targeted six times and yielded two catches while notching three pass breakups and one interception. Lattimore’s ability to lock up his opponent has me concerned with the Panthers’ ability to move the football.

Bettors should proceed cautiously when extrapolating data from prior seasons, given that the team today is different from what they were then. However, the Saints’ history against rookie quarterbacks since Lattimore came into the league is worth examining. In eight games against rookie quarterbacks since 2017, the Saints have allowed an average of 15 points per game. That includes games where Justin Herbert and the Chargers scored 27, and Jalen Hurts’ Eagles logged 24. For reference, Lattimore accumulated three interceptions in these eight games. The combination of Allen and Lattimore thrives against rookies.

We should probably tamper our expectations of the Panthers rookie quarterback for a few weeks. Whether it’s lack of game reps or the rookie getting accustomed to the league, he finished No. 25 in EPA per dropback during Week 1. Should we expect that to improve against a better Saints defense?


The Saints’ offensive line has their work cut out for them Monday night, with Brian Burns opposite them. The fifth-year pro out of FSU is widely regarded as one of the best pass rushers in the league but has flown under the radar due to the team he’s playing for. In just 24 passing downs last week, the Panthers’ defense accumulated seven pressures and four sacks. That puts them in the middle of the pack after the opening week and a date with a second-year tackle who struggled mightily in Week 1. The Saints’ starting left tackle, Trevor Penning had an awful opening week, allowing six pressures and two sacks of Carr. I’d look for the Panthers to try and exploit this with Burns in obvious passing situations.

On the other hand, the Saints receivers have a massive advantage with Horn sidelined for a few weeks. CJ Henderson was the next man up for the Panthers when Horn exited Week 1, and Henderson was targeted twice in 12 snaps. Look for the “slant king,” Michael Thomas, to feast under the Monday night lights.


Since these defenses have advantages in the trenches, I lean towards the under here. The Panthers only came away with 10 points last week against a vulnerable Falcons front. I’d expect Frank Reich’s squad to struggle to move the ball against a nasty Saints defense. If you’re into trends, all three prime-time games went under the total last week.


At the end of the day, I don’t have confidence in the Panthers keeping Young upright for four quarters. That, coupled with the stout secondary that the Saints possess, makes the division underdog unappealing for me. This game is going to be won or lost in the trenches, and I can see the rookie QB coughing up the football a few times in his home opener. Instead of playing a side in this one, I took Panthers under 18.5 (-106) total points at FanDuel on Tuesday. Best of luck betting Saints vs. Panthers odds!

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