NCAA Tournament Round of 32 Preview: March Madness Saturday Prediction Markets

Written By Caleb Tallman | Published at March 20, 2026
Mar 19, 2026; Buffalo, NY, USA; Michigan State Spartans forward Coen Carr (55) dunks during the second half against the North Dakota State Bison during a first round game of the men's 2026 NCAA Tournament at Keybank Center. Mandatory Credit: Mark Konezny-Imagn Images

Day one of the NCAA Tournament did not disappoint, with some electric action, upsets, and heavyweights getting tested. Duke was almost upset by Siena, trailing at halftime, while High Point upset Wisconsin, and teams like Michigan State, Michigan, and Houston cruised to easy wins. There are eight Round of 32 matchups on Saturday, and Sports Prediction Markets' probabilities are getting tighter with each Round of March Madness.

Just like we did in Round 1, we have everything you need to know about all the matchups from the best Prediction Market apps. Add in expert analysis and up-to-date Prediction Market prices, and we also share where to watch Round of 32 NCAA Tournament matchups and the NCAA Tournament locations for all games.

Prices for all games below via Kalshi, taken on March 20, at 1:42 p.m. ET.

#1-#9 Duke vs. TCU Preview & Predictions Markets

Duke was almost subjected to the third-ever 16-seed upset of a 1-seed. Duke Coach Jon Scheyer admitted postgame that his team was outcoached and was not ready for this matchup. It will be an important lesson for a team made up of many young freshmen. In comparison, TCU played really well and held off a late Ohio State run to advance to this Round. They will need more, though, to beat a Duke squad that will not likely underestimate an opponent again. The Kalshi prices reflect this, as the Blue Devils are a double-digit favorite.

Kalshi MarketYesNo
Duke to WinYes 86¢No 15¢
TCU to WinYes 15¢No 86¢
Duke Wins by Over 10.5 pointsYes 56¢No 46¢
Over 139.5 Points ScoredYes 52¢No 50¢

Where/When to Watch Duke vs. TCU: Sat. March 21, 5:15 p.m. CBS

Duke vs. TCU Location: Bon Secours Wellness Arena, Greenville, SC

#3-#6 Michigan State vs. Louisville Preview & Predictions Markets

Michigan State did what was expected of them and dominated North Dakota State, while Louisville barely survived to beat South Florida. The Prediction Market News has the Spartans as the early favorite in this matchup. If Michigan State, led by All-American point guard Jeremy Fears Jr., plays to their potential, they should handle a Cardinals team missing their best player, Mikel Brown Jr., who is out injured.

Kalshi MarketYesNo
Michigan State to WinYes 64¢No 37¢
Louisville to WinYes 37¢No 64¢
Michigan State Wins by Over 3.5 pointsYes 56¢No 45¢
Over 151.5 Points ScoredYes 50¢No 51¢

Where/When to Watch Michigan State vs. Louisville: Sat. March 21, 2:45 p.m. CBS

Michigan State vs. Louisville Location: Viejas Arena, San Diego, CA

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Where/When to Watch Vanderbilt vs. Nebraska: Sat. March 21, 8:45 p.m. TNT

Vanderbilt vs. Nebraska Location: KeyBank Center, Buffalo, NY

#3-#11 Illinois vs. VCU Preview & Predictions Markets

Illinois pummeled Penn in their first-round game, as they simply had too much size and strength for them. Their guards will have to be able to handle the pressure VCU applies, though, something that led to a huge comeback win in overtime over North Carolina in the first Round. VCU had to use everything at its disposal to win, though, and you have to wonder if it will have enough legs left to go 40 minutes with the Fighting Illini.

Kalshi MarketYesNo
Illinois to WinYes 84¢No 17¢
VCU to WinYes 17¢No 84¢
Illinois Wins by Over 10.5 pointsYes 53¢No 48¢
Over 152.5 Points ScoredYes 49¢No 52¢

Where/When to Watch Illinois vs. VCU: Sat. March 21, 7:50 p.m. CBS

Illinois vs. VCU Location: Bon Secours Wellness Arena, Greenville, SC

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Where/When to Watch Houston vs. Texas A&M: Sat. March 21, 6:10 p.m. TNT

Houston vs. Texas A&M Location: Paycom Center, Oklahoma City, OK

#4-#12 Arkansas vs. High Point Preview & Predictions Markets

Arkansas looks to end High Point's Cinderella run after the Panthers pulled off one of the biggest upsets of the first Round. This matchup will likely be the highest-scoring game in the Round of 32, as Arkansas dropped 97 points against Hawaii, while High Point had 83 of their own against Wisconsin. This game will be a shootout, but Arkansas has elite guard play, and it seems likely that they will put the Panthers out of reach late in the second half.

Kalshi MarketYesNo
Arkansas to WinYes 86¢No 15¢
High Point to WinYes 15¢No 86¢
Arkansas Wins by Over 10.5 pointsYes 54¢No 47¢
Over 168.5 Points ScoredYes 53¢No 49¢

Where/When to Watch Arkansas vs. High Point: Sat. March 21, 9:45 p.m. TBS

Arkansas vs. High Point Location: Moda Center, Portland, OR

#3-#11 Gonzaga vs. Texas Preview & Predictions Markets

Gonzaga struggled to put away a feisty Kennesaw State team in the first Round while Texas won its second game in three days to beat BYU. One has to wonder whether Texas, after winning a First Four Game and a Round of 64 game, could suffer from some tired legs. If they find a way to gut it out, though, they probably have better guard play than Gonzaga and have the size to slow down the Bulldogs star big man Graham Ike (19.7 PPG & 8.2 RPG).

Kalshi MarketYesNo
Gonzaga to WinYes 70¢No 32¢
Texas to WinYes 32¢No 70¢
Gonzaga Wins by Over 5.5 pointsYes 53¢No 48¢
Over 147.5 Points ScoredYes 50¢No 51¢

Where/When to Watch Gonzaga vs. Texas: Sat. March 21, 7:10 p.m. TBS

Gonzaga vs. Texas Location: Moda Center, Portland, OR

#1-#9 Michigan vs. Saint Louis Preview & Predictions Markets

St. Louis, in another part of the bracket, could be a trendy pick to make a Cinderella run, but it's a tough matchup against Michigan. The Wolverines are uniquely equipped with plenty of size to slow down the Bilikens' star center Robbie Avila. Of St. Louis five losses this season, four came when Avila scored 14 or fewer points. The Wolverines can do that, making them the obvious favorite.

Kalshi MarketYesNo
Michigan to WinYes 88¢No 13¢
Saint Louis to WinYes 12¢No 89¢
Michigan Wins by Over 12.5 pointsYes 51¢No 50¢
Over 161.5 Points ScoredYes 51¢No 50¢

Where/When to Watch Michigan vs. Saint Louis: Sat. March 21, 12:10 p.m. CBS

Michigan vs. Saint Louis Location: KeyBank Center, Buffalo, NY