San Francisco 49ers Betting Odds

Schedule, Spread, And Predictions

6 – 11 – 0
49ers 2024 season stats
RANKING 4th IN THE NFC WEST
OFFENSIVE RANK 4th YARDS PER GAME YPG
DEFFENSIVE RANK 7th YARDS PER GAME YPG
POINT DIFFERENTIAL -47 POINTS
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The San Francisco 49ers continue to deal deal with significant injuries to key players. The 49ers have San Francisco 49ers +95455 Super Bowl odds. Below, you will find San Francisco 49ers odds for 2024, including a weekly outlook, spreads for every game, futures, and more from the best NFL betting sites.

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49ers odds

View San Francisco 49ers odds for the current season below, including for their next game.

49ers Super Bowl odds

View 49ers Super Bowl odds below.

49ers NFC West Odds

The 49ers opened the season with -210 odds to repeat as NFC West champs.

49ers Win Total

The 49ers opened the 2024 season with a projected win total of 11.5. The opening price on the over was +100.

49ers prop bets

Search below for San Francisco 49ers odds, team or player props currently being offered at sportsbooks. You can also look around at other teams and players using this tool. Happy shopping!

San Francisco 49ers Injuries

Last Updated on 12.10.2024
Player Pos Position Injury Status Snaps/g Snaps Per Game Comment
There Aren’t Any Injured Players for This Team Currently

2024 49ers Player Stats

Last Updated on 12.10.2024
Player GP Games Played CMP% Completion Percentage YDS Passing Yards YDS/G Yards Per Game YDS/C Yards Per Completion TDS Passing Touchdowns INT Interceptions thrown RTG Passer Rating
Brock Purdy – QB 1565.9%3,864257.612.9201296.4
Joshua Dobbs – QB 268.1%361180.511.322100.3
Brandon Allen – QB 356.7%19966.311.71269.2
Player GP Games Played ATT Rushing Attempts YDS Rushing Yards YDS/C Yards Per Carry YDS/G Rushing Yards Per Game TDS Rushing Touchdowns
Jordan Mason – RB 121537895.265.83
Isaac Guerendo – RB 16844205.026.34
Brock Purdy – QB 15663234.921.55
Christian McCaffrey – RB 4502024.050.50
Patrick Taylor Jr. – RB 13391834.714.11
Deebo Samuel Sr. – WR 15421363.29.11
Ricky Pearsall – WR 1134515.04.10
Joshua Dobbs – QB 29242.712.02
Jacob Cowing – WR 15177.00.50
Brandon Allen – QB 3341.31.30
Player GP Games Played TGTS Targets REC Receptions YDS Receiving Yards CTP% Catch Percentage YDS/R Yards Per Reception YAC/G Yards After Catch Per Game TDS Receiving Touchdowns
George Kittle – TE 1594781,10683.0%14.234.88
Jauan Jennings – WR 151137797568.1%12.715.96
Deebo Samuel Sr. – WR 15815167063.0%13.128.13
Ricky Pearsall – WR 11463140067.4%12.910.43
Brandon Aiyuk – WR 7472537453.2%15.014.60
Isaac Guerendo – RB 16161515293.8%10.16.70
Christian McCaffrey – RB 4191514678.9%9.724.50
Eric Saubert – TE 1714119778.6%8.81.11
Jordan Mason – RB 1214119178.6%8.34.80
Jacob Cowing – WR 15648066.7%20.01.70
Chris Conley – WR 151267650.0%12.71.30
Patrick Taylor Jr. – RB 131132527.3%8.31.50
Isaiah Hodgins – WR 32212100.0%6.00.30
Trent Taylor – WR 21111100.0%11.01.00
Brayden Willis – TE 102000.0%0.00.00
Jake Tonges – TE 160000.0%0.00.00
Player GP Games Played INT Interceptions PD Passes Defended FF Fumbles Forced FR Fumbles Recovered SACK QB Sacks TOT Total Tackles SOLO Solo Tackles AST Assisted Tackles
Nick Bosa – DL 1410119523319
Leonard Floyd – DE 1700009422517
Maliek Collins – DT 1700025332013
Yetur Gross-Matos – DL 110000419145
Kevin Givens – DL 8001041165
Fred Warner – LB 17204011317655
Javon Hargrave – DL 300001743
Khalil Davis – DT 13000011275
Deommodore Lenoir – CB 1520100855332
Nick McCloud – CB 900000231310
George Odum – S 12000001192
De’Vondre Campbell Sr. – LB 1300000794435
Ji’Ayir Brown – S 1710000774928
Dee Winters – LB 1500000402218
Rock Ya-Sin – CB 400000220
Demetrius Flannigan-Fowles – LB 12100001183
Dre Greenlaw – LB 200000936
Alex Barrett – DL 300000110
Isaac Yiadom – CB 151021044359
Curtis Robinson – LB 300000000
Robert Beal Jr. – DL 14000001165
Renardo Green – CB 1610100604020
Tre Avery – CB 200000000
Darrell Luter Jr. – CB 100100000
Charvarius Ward – CB 1200000543816
Jalen Graham – LB 800000624
Jordan Elliott – DT 150000019127
Talanoa Hufanga – S 700000382018
Tatum Bethune – LB 1100010404
Tarron Jackson – OLB 300000000
Tashaun Gipson Sr. – S 900000651

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49ers schedule

Here are the opening odds for every 49ers game this season.

Week DateOpponentKickoff TimeOpening Odds
Week 1Monday, September 9New York Jets 8:20 p.m. ET-6
Week 2Sunday, September 15at Minnesota Vikings1 p.m. ET-6
Week 3Sunday, September 22at Los Angeles Rams4:25 p.m. ET-2.5
Week 4Sunday, September 29New England Patriots4:05 p.m. ET-11.5
Week 5Sunday, October 6Arizona Cardinals 4:05 p.m. ET-9.5
Week 6Thursday, October 10 at Seattle Seahawks8:15 p.m. ET-4
Week 7Sunday, October 20Kansas City Chiefs 4:25 p.m. ET-2
Week 8Sunday, October 27Dallas Cowboys8:20 p.m. ET-4.5
Week 9BYE WEEK
Week 10Sunday, November 10at Tampa Bay Buccaneers1 p.m. ET-4
Week 11Sunday, November 17 Seattle Seahawks4:05 p.m. ET-9
Week 12Sunday, November 24at Green Bay Packers4:25 p.m. ET-2.5
Week 13Sunday, December 1at Buffalo Bills8:20 p.m. ET-2
Week 14Sunday, December 8Chicago Bears 4:25 p.m. ET-5.5
Week 15Thursday, December 12Los Angeles Rams8:15 p.m. ET-6.5
Week 16Sunday, December 22 at Miami Dolphins4:25 p.m. ET-1
Week 17Monday, December 30Detroit Lions8:15 p.m. ET-4.5
Week 18Sunday January, 5at Arizona CardinalsTBD-5.5

How to bet on the San Francisco 49ers

Moneyline

The moneyline is the simplest of bets, decided by the straight-up winner and loser of each game. Consider the following example:

  • 49ers -185
  • Panthers +310

The 49ers are considered heavy favorites in this matchup (indicated by -185), requiring a $185 bet to win $100 (plus the initial bet back). The Panthers are the underdog in this matchup, paying out $410 total for a $100 bet ($310 in winnings). How much either team wins or loses by does not matter in moneyline betting, the payout remains the same.

Point spread

Betting on the point spread is determinant on how many points a team wins or loses by. Take the following example:

  • 49ers -6.5 (-110)
  • Dolphins +6.5 (-110)

In this example, San Francisco is favored by 6.5 points, indicated by “-6.5.” If the 49ers win the game 27-20, the 49ers (-6.5) win the bet and would have a total payout of $19.09 on a $10 bet ($9.09 in profit). If the Dolphins keep the game within seven and lose 23-17, the Dolphins (+6.5) would win, and the payout would be the same as listed above.

Point total (over/under)

The point total refers to the over/under line set by books. This number projects the total number of points scored in a game and, like prop betting, is bet whether one thinks the score will go over or under the set point total. For example, the 49ers’ Week 7 matchup with the New England Patriots had a projected point total of 47.5 points. San Francisco won that game 33-7, resulting in 40 points being scored. Those that bet under the point total would have cashed out.

The 49ers have fielded one of the most potent defenses and dangerous running games in the NFL for the past few seasons; the Kyle Shanahan system specializes in diversifying their offensive weapons and getting as many athletes involved in the game as possible. As a result, the 49ers aren’t quick-scoring, one-play threatening, and usually garner lower point totals. Typical over/unders for games involving the 49ers sit between 45 and 49 points.

In-play and live betting

Sometimes, the most thrilling and rewarding bets are bets made while watching the games. These are referred to as live bets or in-play bets. Odds are ever-changing during games, which would prove to be fruitful for sharp and prepared bettors. For example, if the 49ers (-225) were heavily favored against the Raiders (+190) before kickoff, a payout on a $10 bet on the 49ers to win would win just $4.44.

However, say the 49ers fell to a big 17-3 deficit in the first half despite controlling the overall game (due to a costly turnover or special teams gaffe). Odds may swing in favor of the Raiders, who may be a -110 favorite at halftime. Taking the 49ers to come back and win the game could present plus-odds (say, +130). Should a bettor take San Francisco (+130) at halftime and the 49ers pull off the comeback, winners would win $13 instead of $4.44 (plus the initial $10 bet).

This could also be an effective way to “hedge” your bet; say a bettor took the Raiders (+190) in that game, but San Francisco jumps out to a 21-0 first quarter lead and is controlling the overall feel of the game, bettors could hedge by throwing some money down on San Francisco (-270) to return some of the inevitably-lost bet.

Parlays and teasers

You can always string bets together in the form of parlays or teasers. Usually during busy Sundays, bettors can parlay several teams to win or cover against the spread and if all bets are successful, the payouts are multiplied. Teasers function similarly, except they allow bettors to move each point spread to a more favorable line in exchange for diminished odds.

Futures

Futures are long-term bets that can range from an offseason to a full season (or beyond). Team win totals, award winners, and player performance are common futures.

Over/under record: 10-7

Compare Betting Sites & Apps For The Best 49ers Odds

For experienced bettors, the odds on the San Francisco 49ers can change quickly due to player performances and game matchups, making it essential to stay up-to-date. Comparing top sports betting sites is key to finding the most favorable odds and a variety of betting markets. Leveraging leading sports betting apps allows you to place bets on the go, track live line movements, and capitalize on emerging opportunities. With a strategic approach and the right tools, you can refine your betting strategy and maximize your potential returns when wagering on the 49ers.