Carolina Panthers Betting Guide

Odds, Schedule And Predictions


Matt Rhule and the Carolina Panthers coaching staff may be coaching on their last legs. They missed out on multiple quarterback sweepstakes and have been reported to be “comfortable” rolling into 2022 with Sam Darnold. They also lost multiple defensive staples, chiefly Haason Reddick, this offseason. They drafted highly, picking NC State’s Ikem Ekwonu sixth overall. The Panthers may be in limbo unless someone surprises the league.

Below, you can find Carolina Panthers odds for 2022. Included is a weekly outlook, odds for every game this season, futures, and more.

Week 1 Preview: Browns at Panthers

The Carolina Panthers are home underdogs to open their 2022 season against the Cleveland Browns. This is a line with a ton of volatility this offseason as both teams’ quarterback situations clear up. Keep an eye on NFL news that may send this line moving one way or another. Ultimately, the Panthers are unlikely to become favorites in this game, but they could become steeper underdogs. The over/under is set at .

Panthers betting news

Panthers 2022 offseason moves

Key signings: DL Matt Ioannidis, P Johnny Hekker, WR Rashard Higgins, OL Austin Corbett, SAF Xavier Woods, OL Bradley Bozeman

Re-signings: TE Ian Thomas (3 years), WR D.J. Moore

Trades: None

Key losses: CB A.J. Bouye (cut), CB Stephon Gilmore, EDGE Haason Reddick

Key draft picks: OT Ikem Ekwonu, QB Matt Corral, LB Brandon Smith, EDGE Amare Barno

Carolina Panthers 2022 schedule and betting odds

Week DateOpponentKickoff Time
Week 1Sunday, Sept. 11vs. Cleveland Browns1 p.m. ET
Week 2Sunday, Sept. 18at New York Giants1 p.m. ET
Week 3Sunday, Sept. 25vs. New Orleans Saints1 p.m. ET
Week 4Sunday, Oct. 2vs. Arizona Cardinals4:05 p.m. ET
Week 5Sunday, Oct. 9vs. San Francisco 49ers4:05 p.m. ET
Week 6Sunday, Oct. 16at Los Angeles Rams4:05 p.m. ET
Week 7Sunday, Oct. 23vs. Tampa Bay Buccaneers1 p.m. ET
Week 8Sunday, Oct. 30at Atlanta Falcons1 p.m. ET
Week 9Sunday, Nov. 6at Cincinnati Bengals1 p.m. ET
Week 10Thursday, Nov. 10vs. Atlanta Falcons8:15 p.m. ET
Week 11Sunday, Nov. 20at Baltimore Ravens1 p.m. ET
Week 12Sunday, Nov. 27vs. Denver Broncos1 p.m. ET
Week 13Sunday, Dec. 4BYEBYE
Week 14Sunday, Dec. 11at Seattle Seahawks4:25 p.m. ET
Week 15Sunday, Dec. 18vs. Pittsburgh Steelers1 p.m. ET
Week 16Sunday, Dec. 25vs. Detroit Lions1 p.m. ET
Week 17Sunday, Jan. 1at Tampa Bay Buccaneers1 p.m. ET
Week 18Saturday, Jan. 7 OR Sunday, Jan. 8at New Orleans SaintsTBD

Carolina Panthers futures odds

Futures are long-term bets that can range from an offseason to a full season (or beyond). Team win totals, award winners, and player performance are common futures.

Panthers Super Bowl 57 odds

The Carolina Panthers have longshot odds to win Super Bowl LVII.

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Panthers prop bets

Prop bets are based on individual performance, typically surrounding players. After a quiet start to the season, D.J. Moore became an excellent value target for prop betting in the NFL season’s later weeks. For example, Moore’s projected receiving total in the Panthers’ Week 7 matchup with the New Orleans Saints was 67.5 yards. That game, he hauled in 93 yards and those that bet over his receiving prop would have cashed out.

Search below for Carolina Panthers team or player props currently being offered at sportsbooks. You can also look around at other teams and players using this tool. Happy shopping!

How to bet on the Carolina Panthers


The moneyline is the simplest of bets, decided by the straight-up winner and loser of each game. Consider the following example:

  • Ravens -185
  • Panthers +310

The Panthers are heavy underdogs in this matchup, paying out $410 total for a $100 bet ($310 in winnings). The Ravens are the favorites in this matchup (indicated by -185), requiring a $185 bet to win $100 (plus the initial bet back). How much either team wins or loses by does not matter in moneyline betting, the payout remains the same.

Point spread

Betting on the point spread is determinant on how many points a team wins or loses by. Take the following example:

  • Panthers -3.5 (-110)
  • Washington +3.5 (-110)

In this example, Carolina is favored by 3.5 points, indicated by “-3.5.” If the Panthers win the game 24-20, the Panthers (-3.5) win the bet and would have a total payout of $19.09 on a $10 bet ($9.09 in profit). If the Washington keep the game within four and lose 23-17, Washington (+3.5) would win, and the payout would be the same as listed above.

Point total (over/under)

The point total refers to the over/under line set by books. This number projects the total number of points scored in a game and, like prop betting, is bet whether one thinks the score will go over or under the set point total. For example, the Panthers’ Week 8 matchup with the Atlanta Falcons had a projected point total of 44.5 points. The Panthers lost that game 25-17, resulting in 42 total points. Those that bet under the point total would have cashed out.

In-play and live betting

Sometimes, the most thrilling and rewarding bets are bets made while games are being played. These are referred to as live bets or in-play bets. Odds are ever-changing during games, which would prove to be fruitful for sharp and prepared bettors. For example, if the Panthers (-110) were heavily favored against the Jets (+190) before kickoff, a payout on a $10 bet on Carolina to win would win $9.09.

However, say the Panthers fell to a big 21-3 deficit in the first half despite controlling the overall game (due to costly turnovers or a special teams gaffe). Odds may swing in favor of the Jets, who may be a -110 favorite at halftime. Taking the Panthers to come back and win the game could present plus-odds (say, +155). Should a bettor take Carolina (+155) at halftime and the Panthers pull off the comeback, winners would win $15.50 instead of $9.09 (plus the initial $10 bet).

This could also be an effective way to “hedge” your bet; say a bettor took the Jets (+190) in that game, but Carolina jumps out to a 14-0 first quarter lead and is controlling the overall feel of the game, bettors could hedge by throwing some money down on Carolina (-190) to return some of the inevitably-lost bet.

Parlays and teasers

You can always string bets together in the form of parlays or teasers. Usually during busy Sundays, bettors can parlay several teams to win or cover against the spread and if all bets are successful, the payouts are multiplied. Teasers function similarly, except they allow bettors to move each point spread to a more favorable line in exchange for diminished odds.

Panthers 2021 recap

Record: 5-12, Last in NFC South

Record ATS: 5-12

Over/under record: 8-9

Any positive strides made this season by the Panthers were completely marred by a baffling quarterback situation. They finished with the worst record against the spread this season and were one of the most underwhelming teams. Worse yet, Matt Rhule couldn’t decide between a pair of mediocre quarterbacks in Cam Newton and Sam Darnold– indecisiveness that nearly cost him his job. The team let go of offensive coordinator Joe Brady and then the offense got worse. While a franchise quarterback could right the ship for the Panthers, they certainly don’t seem to be headed in the right direction.