The Bills continued to put their crushing Week 1 overtime loss behind them by routing a second straight opponent in Week 3. Buffalo dominated the Commanders on the road by a 37-3 score, setting up a showdown with the equally high-powered Dolphins this coming Sunday. NFL Week 4 odds show the Bills as home favorites.
Below, you can find Buffalo Bills odds for 2023, in addition to every Bills pick in the 2023 NFL Draft. Included is a weekly outlook, odds for every game of the 2024 season, Bills futures, and more.
View Buffalo Bills odds for the 2023 NFL season below. Bills Week 4 odds are already available to bet on below. Compare odds from the top NFL betting sites for their game against the Miami Dolphins.
Miami Dolphins at Buffalo Bills
The Bills opened as a 2.5-point road favorite for their Week 4 game against the Dolphins. The game has an initial total of 53.5-54 points.
The Bills looked like themselves for the second straight game in their Week 3 victory over the Commanders, clicking on both sides of the ball. Josh Allen has bounced back from a three-interception night in the season-opening overtime loss to the Jets to throw for 492 yards with four touchdowns and one interception in the next two games.
That sends the star quarterback into a marquee battle with the Dolphins with plenty of steam, and he may need every bit of it. Miami’s offense looks even more lethal than Buffalo’s and appears set to get Jaylen Waddle back for this game after a Week 3 absence due to a concussion.
The Bills’ defense has taken advantage of facing Zach Wilson, Jimmy Garoppolo and Sam Howell over the first three weeks to surrender just 142.3 passing yards per game thus far, but the caliber of opponent naturally goes way up this week.
The good news for Buffalo is that Miami’s defense has shown vulnerability through both the ground and air, allowing a 68.1 percent completion rate and 130 rushing yards per contest at 4.6 yards per carry (4.9 per road game).
Bills Super Bowl odds
Only Kansas City and Philadelphia have shorter Super Bowl odds in 2024 than the Buffalo Bills. The Bills are favored to win the AFC East and are behind only KC to win the AFC conference title.
Bills AFC East odds
The Bills began the season as favorites to win the AFC East with odds of +120.
Josh Allen and crew currently have odds to win the division.
Bills prop bets
Search below for Buffalo Bills odds, team, or player props currently being offered at sportsbooks. You can also look around at other teams and players using this tool. Happy shopping!
Key signings: OL Connor McGovern, QB Kyle Allen, WR Trent Sherfield, RB Damien Harris, G David Edwards
Re-signings: LB Matt Milano, SAF Jordan Poyer, RB Nyheim Hines, DL Tim Settle, CB Dane Jackson
Trades: Traded DE Boogie Basham for 6th round pick in 2025 NFL Draft
Key losses: LB Tremaine Edmunds, QB Case Keenum, WR Isaiah McKenzie, RB Devin Singletary
Key draft picks: TE Dalton Kincaid (Utah), G O’Cyrus Torrence (Florida), LB Dorian Williams (Tulane), WR Justin Shorter (Florida), G Nick Broeker (Mississippi), CB Alex Austin (Oregon State)
Here’s what the Buffalo Bills roster currently looks like.
Best Bills betting sites
Here are the best Buffalo Bills betting sites.
Here is the Bills schedule for the 2023 – 2024 season. Betting odds are included for each game.
Here are the what Bills opening odds looked like for each game when the schedule was first announced.
|Week||Date||Game||Kickoff Time||Opening Odds|
|Week 1||Monday, September 11||Bills at New York Jets||8:15 p.m. ET||Bills -3|
|Week 2||Sunday, September 17||Raiders at Bills||1 p.m. ET||Bills -7.5|
|Week 3||Sunday, September 24||Bills at Commanders||1 p.m. ET||Bills -4.5|
|Week 4||Sunday, October 1||Dolphins at Bills||1 p.m. ET||Bills -3.5|
|Week 5||Sunday, October 8||Jaguars at Bills (London)||9:30 a.m. ET||Bills -3.5|
|Week 6||Sunday, October 15||Giants at Bills||8:20 p.m. ET||Bills -7|
|Week 7||Sunday, October 22||Bills at Patriots||1 p.m. ET||Bills -2.5|
|Week 8||Thursday, October 26||Buccaneers at Bills||8:15 p.m. ET||Bills -10|
|Week 9||Sunday, November 5||Bills at Bengals||8:20 p.m. ET||Bengals -1|
|Week 10||Monday, November 13||Broncos at Bills||8:15 p.m. ET||Bills -6|
|Week 11||Sunday, November 19||Jets at Bills||4:25 p.m. ET||Bills -3.5|
|Week 12||Sunday, November 26||Bills at Eagles||4:25 p.m. ET||Eagles -1.5|
|Week 13||BYE Week|
|Week 14||Sunday, December 10||Bills at Chiefs||4:25 p.m. ET||Chiefs -3.5|
|Week 15||Sunday, December 17||Cowboys at Bills||4:25 p.m. ET||Bills -4|
|Week 16||Saturday, December 23||Bills at Chargers||8 p.m. ET||Bills -1|
|Week 17||Sunday, December 31||Patriots at Bills||1 p.m. ET||Bills -5.5|
|Week 18||Sunday, January 7||Bills at Dolphins||TBD||Dolphins -1.5|
How to bet on the Buffalo Bills
The moneyline is the simplest of bets, decided by the straight-up winner and loser of each game. Consider the following example:
- Bills -105
- Steelers +130
The Bills are considered slight favorites in this matchup (indicated by -105), requiring a $105 bet to win $100 (plus the initial bet back). The Steelers are the underdog in this matchup, paying out $130 total for a $100 bet ($130 in winnings). How much either team wins or loses by does not matter in moneyline betting, the payout remains the same.
Betting on the point spread is determinant on how many points a team wins or loses by. Take the following example:
- Bills -2.5 (-110)
- Dolphins +2.5 (-110)
In this example, Buffalo is favored by 2.5 points, indicated by “-2.5.” If the Bills win the game 23-20, the Bills (-2.5) win the bet and would have a total payout of $19.09 on a $10 bet ($9.09 in profit). If the Dolphins keep the game within three and lose 24-23, the Dolphins (+2.5) would win, and the payout would be the same as listed above.
Point total (over/under)
The point total refers to the over/under line set by books. This number projects the total number of points scored in a game and, like prop betting, is bet whether one thinks the score will go over or under the set point total. For example, a game between the Patriots and Bills had a point total set at 52.5 points. Buffalo win the ballgame 38-9, which resulted in 47 total points. Those who bet the under in this game would cash out.
The expectation for the Bills’ explosive offense should nudge point totals near or above 50 points, though their talented defense might keep those totals perfectly average in the NFL this coming season.
In-play and live betting
Sometimes, the most thrilling and rewarding bets are bets made while games are being played. These are referred to as live bets or in-play bets. Odds are ever-changing during games, which would prove to be fruitful for sharp and prepared bettors. For example, if the Bills (-225) were heavily favored against the Panthers (+190) before kickoff, a payout on a $10 bet on the Bills to win would win just $4.44.
However, say the Bills fell to a big 17-3 deficit in the first half despite controlling the overall game (due to a costly turnover or special teams gaffe). Odds may swing in favor of the Panthers, who may be a -110 favorite at halftime. Taking the Bills to come back and win the game could present plus-odds (say, +130). Should a bettor take Buffalo (+130) at halftime and the Bills pull off the comeback, winners would win $13 instead of $4.44 (plus the initial $10 bet).
This could also be an effective way to “hedge” your bet; say a bettor took the Panthers (+190) in that game, but Buffalo jumps out to a 10-0 first quarter lead and is controlling the overall feel of the game, bettors could hedge by throwing some money down on Buffalo (-270) to return some of the inevitably-lost bet.
Parlays and teasers
You can always string bets together in the form of parlays or teasers. Usually during busy Sundays, bettors can parlay several teams to win or cover against the spread and if all bets are successful, the payouts are multiplied. Teasers function similarly, except they allow bettors to move each point spread to a more favorable line in exchange for diminished odds.
Futures are long-term bets that can range from an offseason to a full season (or beyond). Team win totals, award winners, and player performance are common futures.
Bills 2022 recap
The AFC East champion Bills, for the second straight season, lost in the Divisional Round of the AFC Playoffs.
Record ATS: 8-9-1
Over/under record: 7-11