Arizona Cardinals Odds

Schedule, Betting Guide, And Predictions

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The Arizona Cardinals are in the running for the NFL’s worst team in 2023. Arizona will be without QB Kyler Murray for at least the first half of the season following ACL surgery in December. Arizona’s roster has been drastically reworked with a slew of signings, releases, and free agency losses. This includes cutting WR DeAndre Hopkins (with a dead cap hit of $22.6 million). Depending on the sportsbook, the Arizona Cardinals odds to win the Super Bowl range between +18000 and +20000.

Below, you can find Arizona Cardinals odds for 2023. Included is a weekly outlook, odds for every game this season, futures, and more.

Arizona Cardinals odds

View Arizona Cardinals odds for the 2023 NFL season below. Cardinals Week 1 odds are already available to bet on. Compare NFL betting odds for their game at the Washington Commanders.

Arizona Cardinals at Washington Commanders .

The Cardinals opened as +5.5 underdogs for their Week 1 game at the Commanders. The game had an initial total of 40.5 points.

Cardinals betting

Cardinals betting futures are also available to bet on now. See the best prices below.

Cardinals transactions

Key signings: DL L.J. Collier, WR Zach Pascal, LB Krys Barnes, LB Josh Woods, OL Dennis Daley,  LB Krys Barnes, DL Carlos Watkins, OL Elijah Wilkinson, CB Kris Boyd, OL Jackson Barton, QB Jeff Driskel

Re-signings: WR Greg Dortch, CB Antonio Hamilton, QB David Blough


Key losses: J.J Watt, C Rodney Hudson, WR Robbie Anderson, LB Markus Golden, DL Michael Dogbe, OL Cody Ford, WR DeAndre Hopkins

Key draft picks: OT Paris Johnson Jr., Ohio State (sixth overall), EDGE BJ Ojulari, LSU (second round, 41st overall), CB Garrett Williams, Syracuse (third round, 72nd overall), WR Michael Wilson, Stanford (third round, 94th overall), OL Jon Gaines II, UCLA (fourth round, 122nd overall), QB Clayton Tune, Houston (fifth round, 139th overall), LB Owen Pappoe, Auburn (fifth round, 168th overall), CB Kei’Trel Clark, Louisville (sixth round, 180th overall), DE Dante Stills, West Virginia (sixth round, 213th overall)

Cardinals Props Bets

Search below for Arizona Cardinals team or player props currently being offered at sportsbooks. You can also look around at other teams and players using this tool. Happy shopping!

Arizona Cardinals Super Bowl odds

The Arizona Cardinals are to win Super Bowl 58.

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Arizona Cardinals 2023 schedule

Week DateOpponentKickoff TimeOpening OddsClosing LineFinal Score
Week 1Sunday, September 10at Washington Commanders1 p.m. ET+5.5
Week 2Sunday, September 17vs. New York Giants 4:05 p.m. ET +4
Week 3Sunday, September 24vs. Dallas Cowboys 4:25 p.m. ET +6.5
Week 4Sunday, October 1at San Francisco 49ers 4:25 p.m. ET +9.5
Week 5Sunday, October 8vs. Cincinnati Bengals 4:05 p.m. ET +7.5
Week 6Sunday, October 15at Los Angeles Rams 4:25 p.m. ET +4.5
Week 7Sunday, October 22at Seattle Seahawks 4:05 p.m. ET +7
Week 8Sunday, October 29 vs. Baltimore Ravens 4:25 p.m. ET +5.5
Week 9Sunday, November 5at Cleveland Browns 1 p.m. ET +7
Week 10Sunday, November 12vs. Atlanta Falcons 4:05 p.m. ET +1.5
Week 11Sunday, November 19at Houston Texans 1 p.m. ET +1.5
Week 12Sunday, November 26 vs. Los Angeles Rams 4:05 p.m. ET +2
Week 13Sunday, December 3at Pittsburgh Steelers 1 p.m. ET +6.5
Week 14Bye Week BYE WEEK
Week 15Sunday, December 17 vs. San Francisco 49ers 4:05 p.m. ET +6.5
Week 16Sunday, December 24 at Chicago Bears 4:25 p.m. ET +4.5
Week 17Thursday, December 31at Philadelphia Eagles 1 p.m. ET +10
Week 18TBD Seahawks TBD +4.5

How to bet on the Arizona Cardinals


The moneyline is the simplest of bets, decided by the straight-up winner and loser of each game. Consider the following example:

  • Cardinals -135
  • Giants +180

The Cardinals are considered favorites in this matchup (indicated by -135), requiring a $135 bet to win $100 (plus the initial bet back). The Giants are the underdog in this matchup, paying out $280 total for a $100 bet ($180 in winnings). How much either team wins or loses by does not matter in moneyline betting, the payout remains the same.

Point spread

Betting on the point spread is determinant of how many points a team wins or loses by. Take the following example:

  • Cardinals -4.5 (-110)
  • Broncos +4.5 (-110)

In this example, Arizona is favored by 4.5 points, indicated by “-4.5.” If the Cardinals win the game 27-20, the Cardinals (-4.5) win the bet and would have a total payout of $19.09 on a $10 bet ($9.09 in profit). If the Broncos keep the game within five and lose 23-21, the Broncos (+4.5) would win, and the payout would be the same as listed above.

Point total (over/under)

The point total refers to the over/under line set by books. This number projects the total number of points scored in a game and, like prop betting, is bet whether one thinks the score will go over or under the set point total. For example, the Cardinals’ Week 10 matchup with the Buffalo Bills had a projected point total of 56.5 points. Arizona won the game 32-30 in thrilling fashion, resulting in 62 combined points. Those that bet over the point total would have cashed out that week.

The Cardinals offense, led by Kyler Murray, proved they were able to score quickly and efficiently. However, it was inconsistent at times and the team as a whole was marred by penalties. These factors are usually balanced out to give the Cardinals average over/under totals, frequently between 48 and 53 points.

In-play and live betting

Sometimes, the most thrilling and rewarding bets are bets made while games are being played. These are referred to as live bets or in-play bets. Odds are ever-changing during games, which would prove to be fruitful for sharp and prepared bettors. For example, if the Cardinals (-225) were heavily favored against the Jaguars (+190) before kickoff, a payout on a $10 bet on the Cardinals to win would win just $4.44.

However, say the Cardinals fell to a big 21-3 deficit in the first half despite controlling the overall game (due to a costly turnover or special teams gaffe). Odds may swing in favor of the Jaguars, who may be a -110 favorite at halftime. Taking the Cardinals to come back and win the game could present plus-odds (say, +110). Should a bettor take Arizona (+110) at halftime and the Cardinals pull off the comeback, winners would win $11 instead of $4.44 (plus the initial $10 bet).

This could also be an effective way to “hedge” your bet; say a bettor took the Jaguars (+190) in that game, but Arizona jumps out to a 20-3 first half lead and is controlling the overall feel of the game, bettors could hedge by throwing some money down on Arizona (-255) to return some of the inevitably-lost bet.

Parlays and teasers

You can always string bets together in the form of parlays or teasers. Usually during busy Sundays, bettors can parlay several teams to win or cover against the spread and if all bets are successful, the payouts are multiplied. Teasers function similarly, except they allow bettors to move each point spread to a more favorable line in exchange for diminished odds.


Futures are long-term bets that can range from an offseason to a full season (or beyond). Team win totals, award winners, and player performance are common futures.

Cardinals 2021 recap

Record: 11-6, Second in NFC West. Lost Wild Card round to Rams

Record ATS: 10-7

Over/under record: 8-9

Seven straight wins to open the season turned into 4-6 down the stretch and a first-round exit in the playoffs. Defensively, the Cardinals were one of the better teams in the NFL, consistently applying pressure to opposing QBs and forcing turnovers. However, Kliff Kingsbury came under fire when the wheels fell off the offense– supposedly the team’s strongest unit– and Kyler Murray was rendered completely ineffective. With a glut of talent and a team ready to win playoff games, Kingsbury will come under immense pressure to win now.

Where can I bet on sports in Arizona?

Arizona sports betting is expected to launch before the 2021 NFL season, and there will be many options to get a bet down on the Arizona Cardinals or any other NFL team. Here’s a list of legal sportsbook options in Arizona, along with the teams the operators and/or organizations have partnered with: