Arizona Cardinals Odds

Schedule, Betting Guide, And Predictions

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Cardinals 2023 season stats
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The Arizona Cardinals are looking to turn things around from recent losing seasons, with first-round picks WR Marvin Harrison Jr. and DE Darius Robinson looking to contribute. The Cardinals will travel east for their NFL Week 1 game at the Buffalo Bills. See more Cardinals odds below, including spreads for every game this season, futures, props, and more.

Arizona Cardinals odds

View Arizona Cardinals odds for their next game at the Buffalo Bills, taking place on Sunday, September 8.

The Cardinals opened as a -7 underdog, while the initial game total was 48. Arizona was +280 on the moneyline when the lines were first released.

Cardinals Super Bowl Odds

The Cardinals have between +8000 and +10000 Super Bowl odds at most sportsbooks.

cardinals NFC West ODDS

The Cardinals opening odds to win the NFC West were +1100, the longest price among the four division teams.

Cardinals win total

The Cardinals will open the 2024 season with a projected win total of 6.5. The opening price on the over is +116.

Cardinals Props Bets

Search below for Arizona Cardinals team or player props currently offered at sportsbooks. You can also look around at other teams and players using this tool. Happy shopping!

Cardinals roster

Here is a look at the Cardinals current roster.

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Cardinals Schedule

View the Cardinals schedule for the 2024 – 2025 season below, with live betting odds for each game.

Here are what the Cardinals opening odds for each game looked like following the NFL schedule release.

Week DateOpponentKickoff TimeOpening Odds
Week 1Sunday, September 8at Buffalo Bills 1 p.m. ET+7
Week 2Sunday, September 15Los Angeles Rams4:05 p.m. ET+1
Week 3Sunday, September 22Detroit Lions4:25 p.m. ET+4
Week 4Sunday, September 29Washington Commanders4:05 p.m. ET-2
Week 5Sunday, October 6at San Francisco 49ers4:05 p.m. ET+9.5
Week 6Sunday, October 13at Green Bay Packers 1 p.m. ET +5
Week 7Monday, October 21Los Angeles Chargers 8 p.m. ET -1
Week 8Sunday, October 27at Miami Dolphins1 p.m. ET +6
Week 9Sunday, November 3Chicago Bears 4:05 p.m. ET +1
Week 10Sunday, November 10New York Jets 4:25 p.m. ET+3
Week 12Sunday, November 24at Seattle Seahawks 4:25 p.m. ET +3
Week 13Sunday, December 1at Minnesota Vikings 1 p.m. ET+1.5
Week 14Sunday, December 8Seattle Seahawks 4:05 p.m. ET -1
Week 15Sunday, December 15New England Patriots 4:25 p.m.3.5
Week 16Sunday, December 22at Carolina Panthers 1 p.m. ET-1
Week 17TBDat Los Angeles RamsTBD+5
Week 18TBD San Francisco 49ers TBD+5.5

How to bet on the Arizona Cardinals


The moneyline is the simplest of bets, decided by the straight-up winner and loser of each game. Consider the following example:

  • Cardinals -135
  • Giants +180

The Cardinals are considered favorites in this matchup (indicated by -135), requiring a $135 bet to win $100 (plus the initial bet back). The Giants are the underdog in this matchup, paying out $280 total for a $100 bet ($180 in winnings). How much either team wins or loses by does not matter in moneyline betting, the payout remains the same.

Point spread

Betting on the point spread is determinant of how many points a team wins or loses by. Take the following example:

  • Cardinals -4.5 (-110)
  • Broncos +4.5 (-110)

In this example, Arizona is favored by 4.5 points, indicated by “-4.5.” If the Cardinals win the game 27-20, the Cardinals (-4.5) win the bet and would have a total payout of $19.09 on a $10 bet ($9.09 in profit). If the Broncos keep the game within five and lose 23-21, the Broncos (+4.5) would win, and the payout would be the same as listed above.

Point total (over/under)

The point total refers to the over/under line set by books. This number projects the total number of points scored in a game and, like prop betting, is bet whether one thinks the score will go over or under the set point total. For example, the Cardinals’ Week 10 matchup with the Buffalo Bills had a projected point total of 56.5 points. Arizona won the game 32-30 in thrilling fashion, resulting in 62 combined points. Those that bet over the point total would have cashed out that week.

The Cardinals offense, led by Kyler Murray, proved they were able to score quickly and efficiently. However, it was inconsistent at times and the team as a whole was marred by penalties. These factors are usually balanced out to give the Cardinals average over/under totals, frequently between 48 and 53 points.

In-play and live betting

Sometimes, the most thrilling and rewarding bets are bets made while games are being played. These are referred to as live bets or in-play bets. Odds are ever-changing during games, which would prove to be fruitful for sharp and prepared bettors. For example, if the Cardinals (-225) were heavily favored against the Jaguars (+190) before kickoff, a payout on a $10 bet on the Cardinals to win would win just $4.44.

However, say the Cardinals fell to a big 21-3 deficit in the first half despite controlling the overall game (due to a costly turnover or special teams gaffe). Odds may swing in favor of the Jaguars, who may be a -110 favorite at halftime. Taking the Cardinals to come back and win the game could present plus-odds (say, +110). Should a bettor take Arizona (+110) at halftime and the Cardinals pull off the comeback, winners would win $11 instead of $4.44 (plus the initial $10 bet).

This could also be an effective way to “hedge” your bet; say a bettor took the Jaguars (+190) in that game, but Arizona jumps out to a 20-3 first half lead and is controlling the overall feel of the game, bettors could hedge by throwing some money down on Arizona (-255) to return some of the inevitably-lost bet.

Parlays and teasers

You can always string bets together in the form of parlays or teasers. Usually during busy Sundays, bettors can parlay several teams to win or cover against the spread and if all bets are successful, the payouts are multiplied. Teasers function similarly, except they allow bettors to move each point spread to a more favorable line in exchange for diminished odds.


Futures are long-term bets that can range from an offseason to a full season (or beyond). Team win totals, award winners, and player performance are common futures.

Cardinals 2023 recap

The Arizona Cardinals have missed the playoffs seven out of the last eight seasons. They closed out the 2023 season last in the NFC West with a 4-13 record.

Record: 4-13, Fourth in NFC West. Missed the playoffs.

Record ATS: 9-8

Over/under record: 10-7