MNF Week 6 NFL Parlay Picks & Player Props: Commanders vs. 49ers

The Washington Commanders head west to take on the undefeated San Francisco 49ers on Monday night. Here are the latest odds for the NFC matchup, plus our top MNF Week 6 NFL parlay picks & player props.

The Commanders 1-3-1 are coming off a 27-27 tie against the New York Giants in their last game, where terrible late clock management left them crucified in the press last week. The 49ers are one of three undefeated teams and beat the defending Super Bowl champion Seattle Seahawks 32-29 in their last game.

Before we lay out our MNF Week 6 NFL parlay picks & player props, Caesars Sportsbook has the 49ers as a 7.5-point favorite with a total of 51.5.

MNF Week 6 NFL Parlay Picks

Commanders vs. 49ers MNF Parlay #1: 49ers Ride McCaffrey

• Christian McCaffrey 60+ rushing yards: McCaffrey leads the 49ers in rushing, and he has rushed for 60+ yards in three of five games this season, including the last one. The 49ers will look to establish the ground game with McCaffrey, and I expect them to lean on him often in the second half, as I see the 49ers leading. While Washington ranks a solid ninth in run defense, they haven't faced a top-15 rushing offense, and San Fran ranks eighth in that category.
• Christian McCaffrey to record 25+ Rushing Yards in Each Half: Solid odds for this bet at +155, and again, the 49ers will establish the run early and run it often in the second half while leading.

The odds for this parlay are +379, so a $100 bet would pay $479, for a $379 profit.

MNF Parlay: Christian McCaffrey 60+ rushing yards and 25+ rushing yards in each half: (+379, FanDuel)

You can check out our comprehensive parlay betting guide to get detailed information on the popular bet type.

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Commanders vs. 49ers MNF Parlay #2: Daniels Will Shoulder Offensive Load

• Jayden Daniels 40+ rushing yards: Daniels has rushed for over 40 yards in two of three games this season and in the last one rushed for 103 yards. He will have to shoulder the offensive load in this game, not only through the air but on the ground as well, as Washington’s top RB, Jacory Croskey-Merritt, is out with an injury. In the last game against the Giants Daniels rushed for 103 yards.
• Jayden Daniels Over 207.5 passing yards: While Daniels has not passed for over 200 yards in the two full games he played, he will get there tonight. He will have to air it out more often, especially in the second half, when I see the Commanders trying to come back while the 49ers lead. While the 49ers rank seventh in the NFL in pass defense, they have given up an average of 216 passing yards over the last three games.

The odds for this parlay are +277, so a $100 bet would pay $377, for a $277 profit.

MNF Parlay: Jayden Daniels to rush for 40+ yards and pass for 200+ yards: (+277, FanDuel)

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Commanders vs. 49ers MNF Parlay #3: 49ers Stay Perfect

• 49ers to win and cover 7.5-point spread: The 49ers are undefeated and rank third in the NFL in both scoring and opponents’ points allowed. On the other side of the coin, the Commanders rank only 17th in PPG and 30th in points allowed, and they are without their lead running back. Take San Fran to cover even giving 7.5 points, as I think they will win by double digits.
• Over 51.5 points: I don’t see Washington scoring a lot of points, but I do see San Fran doing so. They rank third in the league in scoring, and the Commanders’ defense ranks third-to-last, giving up an average of 29.8 ppg. Washington has an Over record of 4-1 this season, and three of the last four games for San Francisco have gone Over.
• 49ers Over 13.5 points in the first half: The 49ers have been solid in the first half this season, and in three of the last four games they have scored over 13.5 points in the first half. Against a defense that has struggled to keep teams from scoring, San Fran will get off to another solid first-half start and score over 13.5 points.

The odds for this parlay are +469, so a $100 bet would pay $569, for a $469 profit.

MNF Parlay: 49ers to win and cover 7.5-point spread, Over 51.5 points, 49ers to score Over 13.5 points in the first half: (+469, BetMGM)

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Player Props Bets to Consider for MNF Week 6

Player Prop #1: Jayden Daniels anytime TD scorer (not passing): +240

Pretty good odds for Daniels to score a TD, as he had two rushing TDs in the last game and will look to run tonight with Washington’s lead RB out with an injury.

Best Bet: Jayden Daniels anything TD scorer (not passing): (+240, DraftKings)

Feel free to check out our prop betting guide to learn all about prop betting.

Player Prop #2: Terry McLaurin 50+ receiving yards: -103

McLaurin leads the Commanders in receiving yards, has 50+ receiving yards in his last three games, and may get more targets as the second-leading receiver, Stefon Diggs is listed as questionable.

Best Bet: Terry McLaurin 50+ receiving yards: (-103, DraftKings)

Player Prop #3 George Kittle 70+ receiving yards: +103

George Kittle has the second most receiving yards for the 49ers and has at least 70 receiving yards in three of the last four games. He may see even more targets in this game, as leading receiver Mike Evans is listed as questionable.

Best Bet: George Kittle 70+ receiving yards: (+103, DraftKings)