Anytime Touchdown Scorer Picks for Oct. 22: 5 Patriots-Bears TNF Bets
Anytime touchdown scorer picks for Oct. 22 focus on Thursday Night Football, where the New England Patriots travel to Soldier Field to face the Chicago Bears. Both teams enter at 4-2 with legitimate playoff aspirations, making this one of the more interesting standalone games of Week 7.
The big news is that Chicago has Caleb Williams back under center and a deep group of playmakers, while New England has A.J. Brown healthy again alongside Drake Maye and several younger weapons. This NFL matchup could be more defensive than some recent primetime games, but there is still plenty of scoring talent on both sides.
Best anytime touchdown scorer picks for Patriots vs. Bears
Chicago supplies three of the five selections, led by Williams and D'Andre Swift, while New England gives us Brown and Efton Chism III. Luther Burden III rounds out the Bears side as a plus-money receiver with big-play ability.
Here are five anytime touchdown scorer picks for Thursday Night Football.
Anytime TD Prediction #1: Caleb Williams (+350)
Caleb Williams can turn a broken play into a touchdown at any moment.
His passing ability will always be the first thing defenses worry about, but Williams remains dangerous with his legs, especially once the Bears get into scoring territory. He has 110 rushing yards and two rushing touchdowns this season despite missing three games with a hamstring injury.
Williams looked healthy in his return last week, completing 30 of 36 passes for 305 yards and a touchdown against Atlanta while leading Chicago to a 31-23 road win. Even if the Bears don't call many designed quarterback runs, his mobility gives him another way to beat New England. Williams can escape pressure, scramble when coverage holds up and make defenders miss in space.
Near the goal line, one broken play is all it takes. At +350 on most sports betting sites, there is enough value to back one of the NFL's most dynamic young quarterbacks.
Prediction: Caleb Williams anytime touchdown at +350 via FanDuel
Anytime TD Prediction #2: Luther Burden III (+184)
Luther Burden III has become a major part of Chicago's passing attack in his second NFL season. He leads the Bears with 31 receptions and 361 receiving yards through six games, giving Williams a reliable target who can create after the catch and stress a defense in space. He has only one receiving touchdown, but the volume suggests more scoring opportunities should follow.
Chicago doesn't need to manufacture a perfect red-zone possession for Burden to score. If he gets the football with room to work, he has the ability to turn an ordinary reception into a much bigger play. New England is also short-handed in the secondary, with Carlton Davis III among the players ruled out. That could create favorable matchups for Chicago's receivers.
At +184, Burden offers a strong mix of weekly volume and plus-money upside.
Prediction: Luther Burden III anytime touchdown at +184 via BetMGM
Anytime TD Prediction #3: A.J. Brown (+135)
A.J. Brown needs very little introduction. When healthy, Brown remains one of the NFL's most physically dominant receivers and one of the league's best touchdown threats. His combination of strength, route running and ability after the catch makes him difficult to handle anywhere on the field.
Brown suffered a high-ankle sprain in New England's opener and missed four games before returning last week against the Jets. He caught three passes for 27 yards, and more importantly, he is off the final injury report entering Thursday night.
The early 2026 production has been limited, but this is still a receiver with 56 career receiving touchdowns. With another game to get comfortable alongside Drake Maye, this could be the spot where Brown finds the end zone for the first time as a Patriot.
At +135, the talent is worth backing.
Prediction: A.J. Brown anytime touchdown at +135 via BetMGM
New Users – Get $350 in Bonus Bets when you wager $5 for 7 days Anytime TD Prediction #4: D'Andre Swift (-160)
D'Andre Swift is the shortest-priced odds on this card, but his role in Chicago's offense makes the number understandable. Swift has rushed for 398 yards and six touchdowns this season while also contributing as a receiver out of the backfield. He is one of the key cogs in Chicago's offense because he can impact the game in several ways.
We have already seen his multi-touchdown ceiling. Swift scored three times in Chicago's Week 1 win over Carolina, showing how quickly he can take over when the Bears consistently reach the red zone.
New England's defense can make this a difficult game, but the Patriots have been vulnerable enough against the run to keep Swift firmly in play. If Chicago gets close to the goal line, Swift remains one of its most logical options to finish the drive.
Prediction: D'Andre Swift anytime touchdown at -160 via FanDuel
Anytime TD Prediction #5: Efton Chism III (+450)
Efton Chism III is the sleeper pick of the night. He is not yet a household name, but his role in New England's offense is worth watching. Chism has nine catches for 98 yards and a touchdown this season and has already shown he can contribute when his number is called.
New England is also thin at receiver. Romeo Doubs and Mack Hollins are unavailable, leaving Brown, DeMario Douglas, Kyle Williams and Chism as the Patriots' primary healthy wideouts. That should keep Chism involved even with Brown back in the lineup.
For a +450 selection on most sports betting apps, we don't need massive target volume. We need one well-designed play, one red-zone look or one opportunity where the defense loses track of him. That makes Chism an appealing value pick to close out the card.
Prediction: Efton Chism III anytime touchdown at +450 via BetMGM
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