Anytime Touchdown Scorer Picks for Oct. 19: 5 Commanders-49ers MNF Bets

Anytime touchdown scorer picks for Oct. 19 focus exclusively on Monday Night Football, with the Washington Commanders traveling to San Francisco to face the undefeated 49ers, who are among the early Super Bowl favorites. San Francisco enters at 5-0 and has emerged as one of the NFL’s best teams, while Washington sits at 1-3-1 and badly needs a win to begin changing the direction of its season.
The matchup also features several interesting touchdown options on both sides. George Kittle leads the card at nearly even money, while Stefon Diggs and Jayden Daniels offer intriguing Washington options. Kyle Juszczyk and Jordan James give us two increasingly aggressive San Francisco long shots.
Best anytime touchdown scorer picks for Commanders vs. 49ers
San Francisco has scored 20 touchdowns through five games, giving us plenty of reason to target its offense. Washington is the underdog, but Daniels’ mobility and Diggs’ scoring production provide two different paths to a Commanders touchdown.
Here are five anytime touchdown scorer picks for Monday Night Football.
Anytime TD Prediction #1: George Kittle (+105)
George Kittle remains one of Brock Purdy’s most trusted weapons, particularly when San Francisco needs an important play. That has translated directly to touchdowns this season.
Kittle has caught 21 passes for 268 yards and four touchdowns through five games, meaning nearly 20% of his receptions have resulted in six points. He’s already scored in four different games and continues to be one of the 49ers’ most reliable targets near the end zone.
His role could become even more important Monday.
San Francisco enters the game dealing with injuries across its receiving corps, including Deebo Samuel being ruled out and other pass catchers carrying questionable designations. That naturally creates more opportunities for Kittle.
Washington has also had problems defensively, particularly when opposing offenses force its secondary and linebackers into difficult coverage assignments.
Kittle has the size, route-running ability and chemistry with Purdy to exploit those situations. At +105, we’re getting nearly even money on one of San Francisco’s most dependable scoring threats.
Prediction: George Kittle anytime touchdown at +105 via BetMGM
Anytime TD Prediction #2: Stefon Diggs (+220)
Stefon Diggs has quickly shown that he still knows how to find the end zone.
The veteran receiver has three touchdowns in four appearances for Washington this season, including one in Week 1 and two more against Dallas in Week 2. He has 18 catches for 170 yards overall, and while the yardage hasn’t been overwhelming, his scoring production has been excellent.
That’s exactly what matters for this market.
Diggs has dealt with a hamstring issue and enters Monday questionable, so his status needs to be monitored before placing the bet. But if he’s active, +220 provides strong value for a player who has already scored three times.
Washington may also find itself throwing frequently if San Francisco builds an early lead. That type of game script should create opportunities for Diggs, especially near the goal line where his route running can still create separation against tight coverage. He has returned this season looking rejuvenated and has already become an important scoring option for Daniels.
Prediction: Stefon Diggs anytime touchdown at +220 on DraftKings
Anytime TD Prediction #3: Jayden Daniels (+235)
Jayden Daniels is one of the NFL’s most dangerous quarterbacks with the ball in his hands, and his rushing ability creates an entirely different dimension in the touchdown market.
Daniels returned last week and immediately reminded everyone what he can do with his legs. He has MVP upside when healthy, but that hasn't been the case often at this level. Against the Giants, he rushed nine times for 103 yards and two touchdowns. He has now accumulated 203 rushing yards and two scores in only three appearances this season.
That makes the +235 line on most sports betting apps extremely interesting.
Daniels doesn’t need a designed quarterback run to reach the end zone. He can score on an option play, escape pressure and scramble, or simply recognize an open lane when coverage defenders turn their backs.
Washington will also be without leading rusher Jacory Croskey-Merritt, potentially increasing the importance of Daniels as part of the ground game. The 49ers defense presents a difficult challenge, but San Francisco will be without Nick Bosa on Monday. If Washington reaches the red zone, Daniels is a threat to score from virtually anywhere.
Prediction: Jayden Daniels anytime touchdown at +235 via BetMGM
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win Anytime TD Prediction #4: Kyle Juszczyk (+450)
Kyle Juszczyk has never needed a large workload to make an impact in San Francisco’s offense. That’s what makes him interesting at +450.
The veteran fullback has only four receptions this season, but those catches have produced 55 yards and a touchdown. Kyle Shanahan has also spent years finding creative ways to use Juszczyk near the goal line, whether as a receiver leaking out of the backfield or on unexpected rushing opportunities. He’s also expected back after dealing with a knee injury.
Christian McCaffrey obviously remains the primary threat in San Francisco’s backfield, but that attention can actually help Juszczyk. Defenses become so focused on McCaffrey, Kittle and Purdy that a fullback can become an afterthought. One play-action design near the goal line could be all it takes.
At +450 at most sportsbooks, we don’t need consistent volume. We simply need Shanahan to reach into the playbook once.
Prediction: Kyle Juszczyk anytime touchdown at +450 on DraftKings
Anytime TD Prediction #5: Jordan James (+2000)
Jordan James is the true lottery-ticket pick on this card. The young running back is buried behind Christian McCaffrey and Kaelon Black in San Francisco’s backfield and has only four rushing attempts for 15 yards this season.
That lack of volume explains the enormous +2000 price. But the appeal here is less about predicting a major role and more about betting on one opportunity.
San Francisco is favored by more than a touchdown against Washington, which creates the possibility of the 49ers controlling the game and getting deeper into their running back rotation. If that happens, James could see late-game touches or even find himself on the field near the goal line.
He has the burst and elusiveness to take advantage if the opportunity arrives. At 20-to-1 odds, this is obviously the most speculative selection of the five. But for a player who only needs one well-timed touch, the payout makes the gamble interesting.
Prediction: Jordan James anytime touchdown at +2000 via BetMGM