NFL Week 7 Picks and Predictions Today for Every Game
Written By Nick Crain | Last Updated at October 19, 2025
Week 7 of the NFL season delivers one of the most complete Sunday slates yet, featuring marquee matchups and potential statement wins across both conferences. From London to New York, oddsmakers have posted tight lines in several spots — a signal that the betting market sees real balance this week.
Whether you’re looking to back a favorite ready to roll or a live underdog built to cover, there’s no shortage of value on the board. Before locking in your NFL best bets, make sure to compare odds across the top sports betting apps.
Many of the leading books are rolling out new promos ahead of Sunday’s action, so taking advantage of those can make a real difference in maximizing your edge this weekend.
Here’s your guide to Sunday’s NFL Week 7 games, complete with odds, analysis, and the best value plays from across the board.
Rams vs Jaguars (London)
Odds: Rams -3 (ML: Rams -166, Jaguars +140) | Over/Under: 44.5 (via Bet365)
Best Bets:
- Jaguars ML
- Under 44.5
International games tend to see teams struggle to get offense going, so this feels like a game that could be low scoring. While both of these teams have proven to be good, the Jaguars are a great underdog pick here given the value.
Eagles at Vikings
Odds: Eagles -3 (ML: Eagles -130, Vikings +120) | Over/Under: 44.5 (via BetMGM)
Best Bets:
- Eagles ML
- Over 44.5
Although the Vikings have a great home-field advantage, the Eagles are desperate to get back on track. This feels like a game that Philadelphia could win big as the team looks to make a statement.
Patriots at Titans
Odds: Patriots -7 (ML: Patriots -345, Titans +275) | Over/Under: 44.5 (via Caesars Sportsbook)
Best Bets:
- Patriots Cover
- Under 44.5
Bet $1, Double your Winnings on your Next 20 Wagers. Up to $25 Max Bet Per Boost At the top of their division, the Patriots have been better than expected this season. Especially against a Titans team that hasn't been competitive this season, winning by more than a TD should be no problem.
Panthers at Jets
Odds: Panthers -1.5 (ML: Panthers -130, Jets +110) | Over/Under: 43.5 (via Bet365)
Best Bets:
- Panthers ML
- Under 43.5
The Jets still don't have a win, and that may not change this week. The Panthers aren't contenders, but they're certainly good enough to win a game like this today. Make sure to take advantage of Bet365 bonus offers.
Dolphins at Browns
Odds: Browns -2.5 (ML: Browns -135, Dolphins +114) | Over/Under: 43.5 (via BetMGM)
Best Bets:
- Dolphins ML
- Under 43.5
The Browns are the favorite at home in this matchup, but the Dolphins are the better team. That's why taking them to win as an underdog in a low-scoring game with two struggling offenses is a great move. BetMGM has great bonus offers that can be leveraged for these games as well.
Saints at Bears
Odds: Bears -4.5 (ML: Bears -230, Saints +190) | Over/Under: 44.5 (via Caesars Sportsbook)
Best Bets:
- Bears Cover
- Over 44.5
Bet $1, Double your Winnings on your Next 20 Wagers. Up to $25 Max Bet Per Boost The Bears have been significantly better than the Saints this season, so this line feels questionable. Especially at home, expect Chicago to put up points in a hurry and win big.
Raiders at Chiefs
Odds: Chiefs -11.5 (ML: Chief-833, Raiders +650) | Over/Under: 45.5 (via Bet365)
Best Bets:
- Chiefs Cover
- Over 45.5
The Chiefs continue to get better each week, which is scary for the rest of the NFL. Against a bottom-tier Raiders team, Kansas City should be able to clear most of the over on points on its own and win big as a result.
Giants at Broncos
Odds: Broncos -7 (ML: Broncos -375, Giants +295) | Over/Under: 42.5 (via BetMGM)
Best Bets:
- Giants ML
- Over 42.5
As good as the Broncos have been this season, there's something about this Giants team. At plus odds this high, taking New York to upset on the road is tremendous value in what could be a shootout.
Colts at Chargers
Odds: Chargers -1.5 (ML: Chargers -122, Colts +102) | Over/Under: 45.5 (via Caesars Sportsbook)
Best Bets:
- Colts ML
- Over 45.5
Bet $1, Double your Winnings on your Next 20 Wagers. Up to $25 Max Bet Per Boost This is a battle for the top spot in the AFC, so it should be one of the most competitive games of the week. But with how banged up the Chargers are, this is a great spot for the Colts to really become established as a Super Bowl contender, and I think they'll rise to the occasion.
Packers at Cardinals
Odds: Packers -6.5 (ML: Packers -310, Cardinals +250) | Over/Under: 47.5 (via Bet365)
Best Bets:
- Packers Cover
- Under 47.5
Despite struggling at times over the past few weeks, the Packers are one of the best teams in the NFL. With the Cardinals missing Kyler Murray today, it may be a game that doesn't see many points, but Green Bay should win big.
Commanders at Cowboys
Odds: Commanders -1.5 (ML: Comm -148, Cowboys +124) |Over/Under: 54.0 (via BetMGM)
Best Bets:
- Cowboys ML
- Under 54.0
This game will be a shootout, but 54 points is by far the highest over/under of the day. With the Commanders taking the field without their two best receivers, that factors in heavily with the desire to take the under and also the Cowboys coming out on top.
Falcons at 49ers
Odds: 49ers -2.5 (ML: 49ers -135, Falcons +114) | Over/Under: 47.5 (via Caesars Sportsbook)
Best Bets:
- Falcons ML
- Over 47.5
Bet $1, Double your Winnings on your Next 20 Wagers. Up to $25 Max Bet Per Boost Sunday Night Football has a tendency to end up being great football that features chunk plays. As such, the over here feels like a safe bet, while the Falcons as slight underdogs on the road brings value as well.
With a mix of divisional battles, an overseas contest and high-powered offenses, Sunday’s Week 7 lineup has everything bettors could ask for. Finding the right angles early can provide serious value before kickoff.
As always, shop around to ensure you’re getting the best number, and don’t forget to check for updated sportsbook promotions and limited-time offers throughout the day. The margins in NFL betting are razor-thin, but the right combination of timing, line value and promos can turn good picks into great payouts.
All Odds as of 11:59 p.m. on Oct. 18
Mandatory Photo Credit: Geoff Burke-Imagn Images
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