NFL Week 7 Odds: Pro Football Spreads, Moneylines, Over Unders

Written By Juan Carlos Blanco on October 23, 2021 - Last Updated on October 24, 2021

A weekend that featured a few more blowouts than is customary came to a close Monday with the Titans edging the Bills. We now turn to the seventh weekend of the season and updated NFL Week 7 odds are available to bet on now.

The seventh week of the season got started with the Browns winning at home over the Broncos in a defensive struggle. Sunday’s notable early games include Chiefs versus Titans and Bengals versus Ravens conference showdowns. Eagles versus Raiders, Colts versus 49ers and Saints versus Seahawks clashes are among the contests of note in the late window and the Sunday night and Monday night slots.

Let’s take a look at NFL Week 7 odds.

NFL Week 7 odds

Point spreads, moneylines and over unders are available to wager. Check out NFL Week 7 odds below.

How NFL Week 7 odds are changing

Below we look at how NFL Week 7 odds are changing throughout the week. Here are the lookahead lines and we will show the evolution of the lines as we get closer to kickoff of each game.

  • Broncos (+6) vs. Browns (-6)
  • Panthers (-2.5) vs. Giants (+2.5)
  • Jets (+7) vs. Patriots (-7)
  • Chiefs (-3.5) vs. Titans (+3.5)
  • Washington Football Team (+7) vs. Packers (-7)
  • Bengals (+6.5) vs. Ravens (-6.5)
  • Falcons (+2.5) vs. Dolphins (-2.5)
  • Lions (+13.5) vs. Rams (-13.5)
  • Eagles (+2.5) vs. Raiders (-2.5)
  • Bears (+10) vs. Buccaneers (-10)
  • Texans (+14) vs. Cardinals (-14)
  • Colts (+5) vs. 49ers (-5)
  • Saints (-3) vs. Seahawks (+3)

Current spreads

  • Broncos (+1.5) vs. Browns (-1.5)
  • Jets (+7) vs. Patriots (+7)
  • Washington Football Team (+8.5) vs. Packers (-8.5)
  • Chiefs (-4.5) vs. Titans (+4.5)
  • Bengals (+6.5) vs. Ravens (-6.5)
  • Panthers (-3) vs. Giants (+3)
  • Falcons (+2) vs. Dolphins (-2)
  • Lions (+16.5) vs. Rams (-16.5)
  • Eagles (+2) vs. Raiders (-2)
  • Texans (+18) vs. Cardinals (-18)
  • Bears (+11.5) vs. Buccaneers (-11.5)
  • Colts (+3.5) vs. 49ers (-3.5)
  • Saints (-4.5) vs. Seahawks (+4.5)

Thursday, Oct. 21

Broncos at Browns ()

The Broncos continued their slide Sunday against the Raiders following a strong start to the season, as they were thumped at home by a 34-24 score. The Browns were subject to an even bigger humiliation on their home field against the Cardinals, dropping a 37-10 decision that was also costly from an injury standpoint.

Denver’s Teddy Bridgewater may have finished with 334 yards and three touchdowns, but he offset those aesthetically pleasing numbers with four turnovers, including three picks. However, blame can hardly be placed only at his feet, considering the defense gave up 426 total yards and 8.2 yards per play to Derek Carr and teammates. However, that side of the ball should get a nice reprieve on the short week this week, considering Cleveland will be playing without three of its biggest offensive weapons.

Baker Mayfield, Kareem Hunt and Nick Chubb have all been ruled out for the contest. Filling those shoes will be Case Keenum, D’Ernest Johnson and Demetric Felton.

The Browns had originally opened as 6-point favorites in the look-ahead line, their current bleak health situation has whittled down that number significantly.

Sunday, Oct. 24

Washington at Packers ()

Washington fell to 2-4 despite putting up a good fight for most of three quarters against the Chiefs, ultimately losing by a 31-13 margin. The Packers had some struggles early at Soldier Field, but they ultimately pulled away from Justin Fields and company by a 24-14 margin.

Washington’s defense gave up at least 30 points for the third straight contest Sunday, and they’re now conceding an NFL-high 309.5 passing yards per game. Taylor Heinicke wasn’t as effective against what had been a vulnerable KC defense as might have been expected, and he’ll now be challenged versus a Packers unit surrendering the fourth-fewest passing yards per game (206.5). Meanwhile, Antonio Gibson is now dealing with calf issue that forced him from Sunday’s game in addition to a lingering stress fracture in his shin.

The Packers continue to ensure there’s no repeat of its season-opening fiasco against the Saints, with Sunday’s win against the Bears their fifth straight. Green Bay is 2-0 at Lambeau Field thus far with an average margin of victory of 14 points. Washington’s aforementioned sieve-like secondary could certainly facilitate one of Aaron Rodgers’ and Davante Adams’ signature performances, while the increasingly dangerous Aaron Jones-AJ Dillon duo could also make inroads versus a defense that gave up a pair of rushing TDs to Darrel Williams on Sunday.

The Packers have seen their projected advantage grow exponentially since the initial look-ahead number of seven points, with the figure already climbing by nearly a field goal as the week began.

Chiefs () at Titans

The Chiefs took a while to get going, but they avoided what would have been a disastrous 2-4 start to the season by notching a 31-13 win going away versus Washington on Sunday. The Titans took down the Bills on Monday Night Football but the win did little to immediately impact this line as the Chiefs were  -4.5 road favorites over Tennessee Tuesday morning.

Patrick Mahomes’ final 397-yard, two-touchdown tally that he complemented with 31 rushing yards sure comes off like a trademark effort on the one-time league MVP’s part, but the numbers somewhat belie some of his early struggles. Mahomes threw two first-half interceptions before getting hot in the second half, but he now has an uncharacteristic eight over his first six contests. He could well have a tantalizing “get right” matchup in front of him, however, as the Titans defense is still shaky as can be.

Falcons () at Dolphins

The Falcons were on bye in Week 6 and headed into their time off with a 27-20 win over the Jets in London back in Week 5. Matt Ryan impressively threw for 342 yards and two touchdowns despite not having Calvin Ridley and Russell Gage, as rookie tight end Kyle Pitts finally had his first breakout game with a 9-119-1 line. The Dolphins didn’t have any such luck across the pond Sunday, as they fell to the Jaguars on a last-second field goal, 23-20.

Atlanta is just 2-3, but it seems evident that Ryan and his teammates on that side of the ball have made strides since their embarrassing 32-6 loss to the Eagles in Week 1. Ridley, who missed the London game due to a personal issue, is already back with the team to start the practice week, while Gage, who’s missed the last three contests with an ankle injury, was also present for Monday’s session. With Cordarrelle Patterson and Pitts also morphing into high-upside contributors, there could be plenty of plays to be had against a Dolphins defense now allowing 292.5 passing yards per contest and has both starting corners Xavien Howard and Byron Jones dealing with injuries.

Tua Tagovailoa made his return from injured reserve in Sunday’s loss to the Jaguars and was impressive working with a short-handed receiving corps himself, throwing for 329 yards and two touchdowns with one interception. The second-year signal-caller was able to get to that lofty figure without Will Fuller (IR-finger), DeVante Parker (shoulder/hamstring) and Preston Williams (groin), and he’ll hope to least have the latter two available for this interconference clash. However, Miami’s near-complete absence of a running game – the Fins are averaging an NFL-low 71.5 rushing yards per contest – always carries the possibility of making life difficult for whomever is under center.

In a testament to how rough a road it is for the Dolphins at the moment, NFL Week 7 odds show that they are home underdogs to a Falcons team hardly considered a formidable opponent.

Jets at Patriots ()

The Jets were off in Week 6 after dropping a 27-20 decision to the Falcons in London in Week 5. The Patriots engaged in a wire-to-wire battle with the Cowboys before falling in overtime, 35-29.

Zach Wilson has made progress after a rough first three games where he failed to complete 60.0 percent of his throws in any contest and generated a 2:7 TD:INT, including a four-pick game against these same Pats. The rookie has gone on to throw for 489 yards with a couple of touchdowns and interceptions against the Titans and Falcons. With a bye week to further absorb the offense and a recently stated commitment to stop overthinking shorter throws, Wilson will look to pick his spots more carefully in the Week 7 rematch.

Mac Jones has now faced off with Tom Brady and Dak Prescott in two of the last three games and impressively held his own, even if both games ended in losses. Jones and his teammates certainly have an easier path to success on paper in this matchup, especially considering they toppled New York by a 25-6 score back in Week 2. New York is vulnerable through both the ground (123.4 RYPG allowed) and air (278.3 PYPG allowed on road), which could also open things up for a New England running game that is staffed by versatile backs.

Even with the Jets coming off a bye, the fact this is the second meeting between division opponents and New England’s Week 6 loss, the Pats remain the touchdown favorite they opened as.

Panthers () at Giants

The Panthers continued their slide in Week 6, falling to the Minnesota Vikings by a 34-28 score in overtime after mounting a lte comeback. The Giants didn’t have any such close calls, as they got thumped by the Rams at MetLife, 38-11.

It may just be a bump in the road, but Sam Darnold is starting to display some troubling signs after a stellar first four games of the season. The 2018 third overall pick has completed just 48.7 percent of his passes and posted a 2:4 TD:INT over his last two games, looking particularly ineffective for most of regulation versus Minnesota on Sunday. Some dropped passes were partly to blame, and the ongoing absence of Christian McCaffrey (IR-hamstring) certainly doesn’t help. The matchup at least lines up nicely on paper in Week 7, as the G-Men are allowing 264.2 passing yards per contest.

Daniel Jones was able to make it back from his concussion for the matchup against the Rams, although the way things unfolded may have made him wish he sat out the contest. Jones was playing very short-handed, as Saquon Barkley (ankle), Kenny Golladay (knee) and Darius Slayton (hamstring) were all inactive, and impressive rookie Kadarius Toney (ankle) soon joined them on the sideline. The three wideouts could potentially all make their returns against Carolina, while Barkley’s status appears to be more iffy based on his original injury.

Even with both squads struggling at the moment and New York at home, the Panthers are solid road favorites when looking at the NFL Week 7 odds.

Bengals at Ravens ()

In Week 6, the Bengals did what teams looking to be viewed as serious contenders are supposed to – they took care of business against an inferior opponent on the road. Cincy dismantled the Lions methodically by a 34-11 score, a performance that saw the Big Three of Joe Burrow, Joe Mixon and Ja’Marr Chase come through with strong efforts. Meanwhile, the Ravens were just as impressive against a much higher quality of competition, surprisingly dominating the Chargers by a 34-6 margin.

Were it not for the narrow three-point overtime loss to the Packers in Week 5, the Bengals would be heading into this key AFC North matchup as winners of four straight. The defense is clearly improved over last season, while the offense is picking up steam and arguably hasn’t really clicked completely on all cylinders yet. The Ravens will represent their stiffest test yet, a road victory here would be an incalculable confidence booster for Zac Taylor’s squad.

Even with Lamar Jackson putting together a lackluster performance Sunday, Baltimore easily handled the Chargers. The defense, which hadn’t been playing to its usual standard up to this point, picked off Justin Herbert twice and 208 total yards at 3.9 yards per play. On the other side of the ball, while the Ravens did lose Latavius Murray to an in-game ankle injury Sunday, Devonta Freeman turned back the clock a bit with a 9-53-1 line on the ground and fellow vet Le’Veon Bell crossed the goal line as well.

NFL Week 7 odds show that despite Cincinnati’s recent showings, the Ravens – winners of five straight in the series – are unsurprisingly solid home favorites.

Eagles at Raiders ()

The Eagles gave the defending champs a good fight at the Linc last Thursday night before falling, 28-22. The Raiders began the post-Jon-Gruden era with a rousing 34-24 road win in Denver.

Jalen Hurts threw for just 115 yards against a Buccaneers defense that is much easier to pass than run against, certainly a concerning development. Miles Sanders also continued to be underused (nine carries), even though he actually averaged 6.2 yards per tote versus the typically impenetrable front. Hurts will look to get back on track against a Vegas secondary that did pick off Teddy Bridgewater on three occasions Sunday but also allowed him 334 passing yards.

There was naturally an open question about how the Raiders, and especially the offense, would respond to Gruden’s tumultuous and sudden exit, but Vegas delivered an outstanding effort on that side of the ball. Derek Carr averaged 12.6 yards per attempt while racking up 341 yards on just 18 completions, with 48- and 51-yard connections with Henry Ruggs and Bryan Edwards, respectively, playing an important part. The Eagles have allowed just 171.3 passing yards per road game in games versus the Falcons, Cowboys and Panthers, however, so this interconference battle should be a good test.

The public is backing the Raiders after seeing some hard evidence of their ability to bounce back favorably from their head coach’s departure, pushing their projected advantage up as much as a point already after it opened as 2.5.

Lions at Rams ()

The Lions couldn’t put up their usual level of fight in Week 6, falling at home going away to the Bengals, 34-11. The Rams also kept their Week 6 opponent to 11 points while racking up 38 points in a trampling of the Giants on the road.

Jared Goff, who’s been making the best of a questionable receiving corps for most of the season, earned some public critique from his head coach after Detroit’s latest loss, with Dan Campbell saying his quarterback had to “step up more than he has.” Goff threw for a modest 202 yards at just 4.8 yards per attempt in Sunday’s loss, with no pass catcher that recorded more than one reception posting a double-digit YPC figure. The words from his coach could give Goff even more juice for a matchup that marks a return to Los Angeles to face the team that just swapped him for the quarterback he’ll be facing, Matthew Stafford, this past offseason.

Speaking of Stafford, he’ll head into this encounter with his old squad fully looking like the player who got the much better end of the trade between he and Goff. The long-suffering signal-caller has thrived in California sunshine, posting a 16:4 TD:INT and completing a career-best 69.5 percent of his passes through six games.

Cooper Kupp and Stafford have developed an immediate connection, while Darrell Henderson and Sony Michel continue to offer excellent balance on the ground. Coach Sean McVay could well have his pick of how to attack with that array of weapons, considering Detroit is allowing 384.5 total yards per game.

This game unsurprisingly carries one of the slate’s biggest spreads, and it’s already climbed two points from the open following yet another dominant Rams performance Sunday.

Texans at Cardinals ()

The Texans took a step back Sunday against a division opponent after nearly pulling off a big Week 5 upset against the Colts, getting decimated by the Colts, 31-3. The Cardinals took another step toward being recognized as an elite squad of either conference, pasting the Browns on the road by a 37-14 score despite playing without their COVID-sidelined head coach.

Davis Mills didn’t turn in as bad a performance as the final score would imply and the Mark Ingram-Philip Lindsay duo combined for an impressive 112 yards on 25 carries, but the Texans defense didn’t give Houston a chance versus the Colts. The fact Carson Wentz and Jonathan Taylor combined for 368 yards and four touchdowns should be a concern for David Culley and his staff ahead of a date with Kyler Murray and his even more extensive array of weapons.

Arizona’s offense was indeed impressive against what was supposed to be one of the AFC’s best defenses in that of the Browns. Murray only threw for 229 yards and but racked up four touchdowns, while the Cards also compiled 144 rushing yards. Murray continues to flash impressive rapport with several pass catchers, while running back James Conner enjoyed his most efficient day as a Cardinal yet with a 16-71 line on the ground. The Texans could certainly facilitate another big day – Houston is allowing 391.2 total yards per game and 6.2 yards per play.

The Cardinals are even bigger favorites than the Rams are over the Lions, and the betting public has already pushed the look-ahead line of -14 up by another three points.

Bears at Buccaneers ()

The Bears saw their brief two-game winning streak come to an end at Soldier Field on Sunday, as they dropped a 24-14 decision to the Packers on Sunday. The Buccaneers will head into this contest with some extra rest after toppling the Eagles on the road by a 28-22 score on Thursday night.

Justin Fields continued to flash plenty of potential and helped keep Chicago in the game against Green Bay most of the way and also posted his best rushing total as a pro yet (43 yards). Fellow rookie Khalil Herbert was also impressive with 112 total yards and a rushing TD, so there’s certainly hope for the Bears despite their depleted backfield at the moment. However, this matchup should be Fields’ most stringent test yet, considering the road environment, rest advantage for the Bucs, and the highly aggressive nature of their Todd Bowles-coordinated defense.

The Bucs weren’t clicking in all facets Thursday in Philly, but the Tom Brady-Antonio Brown battery proved instrumental in them narrowly prevailing. With a 29-418-4 line through five games and eight catches of over 20 yards, Brown is showing he still has plenty left in the tank and will make defenses pay if they overly focus on Mike Evans and Chris Godwin. Rob Gronkowski is also believed to have a good chance of returning from his rib injury for this contest, which naturally would only make Tampa Bay that much more dangerous.

Although these teams are only two wins apart in their records, the public clearly sees the defending champs as vastly superior – an initial, already robust look-ahead line of Bucs -10 has already been bet up by a field goal or more at multiple sportsbooks.

Colts at 49ers ()

The Colts warmed up for this interconference primetime showdown by decimating their lowly AFC South mates, the Texans, by a 31-3 score Sunday. The 49ers were on bye in Week 6 and went into that time off with a 17-10 loss to the Arizona Cardinals in Week 5.

Indianapolis’ most complete performance of the season saw both Carson Wentz (223 yards, 2 TDs) and Jonathan Taylor (145 rushing yards, 2 TDs) thrive. The Colts defense also finally lived up to its preseason hype to an extent, even though Houston still produced a robust tally – for a team that only scored three points — of 353 total yards. Indy must now try to repeat the feat against a higher caliber of opponent that will be on its home field and coming in more well rested than they are.

The Niners needed the week off after a 2-3 start and that’s featured three consecutive losses. San Fran is still looking for its first home win of the campaign and that has some question marks at quarterback. Rookie Trey Lance has been solid with his opportunities thus far, but he’s now dealing with a knee injury that caused him to miss Monday’s practice. Jimmy Garoppolo, who’s still the presumed starter but missed Week 5 with a calf injury, was able to take the field for Monday’s session, and the status of both players will naturally bear monitoring throughout the week.

The Colt’s blowout win Sunday made an impression on the public, even if it came against the Texans. Indy started out as a 3.5-point favorite in the NFL Week 7 odds look-ahead lines late last week, and that figure has already climbed an appreciable amount after Sunday.

Monday, Oct. 25

Saints () at Seahawks

The Saints enjoyed a bye in Week 6 after a 33-22 win over Washington in Week 5. The Seahawks made a valiant second-half effort Sunday night on the road against the Steelers before falling by a 23-20 score in overtime.
Sean Payton has seemingly opened up the playbook for Jameis Winston a bit more in recent contests, and the results haven’t been bad at all. Although New Orleans only went 1-1 in that span, Winston compiled 505 passing yards and a 5:1 TD:INT. The modest amount of turnovers is particularly important when it comes to the 2015 first overall pick, and he’s displayed improving chemistry with his Michael Thomas-less receiving corps. With a vulnerable secondary in that of Seattle’s on tap, another solid performance through the air could be in store.

Geno Smith put together a solid performance in his first start in place of Russell Wilson (finger) on Sunday night, but his fumble on his fifth sack of the night in overtime set up Pittsburgh’s game-winning field goal. Smith was otherwise competent with 209 yards and a touchdown and Chris Carson stand-in Alex Collins went over the 100-yard mark on the ground against a very tough defense in a matchup that could well have served as a good warmup for another highly aggressive unit in that of the Saints.

The Saints, which will naturally have a notable rest advantage here, opened as field-goal road favorites in the NFL Week 7 odds lookahead lines and have been slightly been bet up slightly subsequent to Seattle’s Week 6 loss.

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Juan Carlos Blanco

Juan Carlos Blanco has served as a freelance writer for a wide variety of online publications and websites, with an intensive focus on fantasy sports. Juan has provided analysis and comprehensive coverage of the MLB, NBA, NFL, CFL, AAF and AFL while also reporting on news and developments in the daily fantasy sports and online gaming industries.

View all posts by Juan Carlos Blanco