NFL Week 6 Betting Preview: Jacksonville Jaguars At Indianapolis Colts

Written By Mo Nuwwarah on October 14, 2022
Jaguars Colts odds

The Jacksonville Jaguars visit the Indianapolis Colts at 1 p.m. ET on Sunday, Oct. 16. Primary markets for the game show the Colts as spread favorites and on the moneyline. Jaguars Colts odds feature a total set at .

In this article, we break down everything you need to know before placing a bet on the game, including team matchups, key metrics, weather and the best available NFL Week 6 odds. Click on the odds anywhere in this post to bet now.

Jaguars At Colts Odds: Spread, Moneyline, Over/Under

When using the odds table, click the dropdown menu and select the type of bet you wish to make. 

Betting the point spread is when you wager on how many points a team will win or lose by. A plus sign in front of the spread denotes the underdog, and a minus sign denotes the favorite.

In this case, the Colts would have to win by at least three points if you bet them to cover the point spread (-2.5). A spread bet on the Jaguars would win if they win the game or lose by less than three. 

Betting the moneyline is simply betting on which particular team will win a game.

The betting total is the number of combined points the two teams will score. Bettors can choose to bet the over or under on how many total points will be scored in the game. 

For more betting guides, click the green NFL Game Previews button at the top of this post.

Editor’s Note

Jaguars At Colts Player Props

In the props tool search bar, type in a team or player and hit enter. You’ll see the various proposition bets offered by leading online sportsbooks. 

This is a valuable tool that allows bettors to compare odds and stats when considering a prop bet. Unlike bigger markets like moneylines and spreads that often reach a consensus number, shopping for prop bet lines can often reveal sizable differences in the numbers.

Jaguars At Colts Betting News & Angles

Use this rolling, updating list of news bites about each team to help your handicapping for Jaguars – Colts odds.

Colts Vs. Jaguars Injury Report

Indianapolis Injuries

Ryan KellyCHipQuestionable
Jonathan TaylorRBAnkleQuestionable
Ashton DulinWRFootOut
Nyheim HinesRBConcussionQuestionable
Darius LeonardLBConcussionQuestionable
Tyquan LewisDEConcussionQuestionable
Julian BlackmonFBAnkleQuestionable
Kwity PayeDEAnkleQuestionable

Jacksonville Injuries

Folorunso FatukasiFBQuadQuestionable
K’Lavon ChaissonOLBKneeOut
Ben BartchOGKneeOut

Colts Offense Vs. Jaguars Defense

Colts OffenseStats (Rank)Jaguars Defense
13.8 (32)Points/Gm16.0 (4)
0.2 (31)Points/Play0.3 (4)
333.0 (24)Yards/Gm313.8 (9)
241.6 (14)Pass Yards/Gm215.6 (14)
91.4 (26)Rush Yards/Gm98.2 (6)
4.9 (26)Yards/Play5.1 (8)
6.2 (23)Yards/Pass6.5 (12)
3.6 (29)Yards/Rush3.7 (4)
36.2% (24)3rd Down %37.7% (14)
40.0% (28)Red Zone %57.1% (15)
11 (30)Turnovers9 (5)
21 (31)Sacks10 (18)

Jaguars Offense Vs. Colts Defense

Jaguars OffenseStats (Rank)Colts Defense
22.2 (15)Points/Gm18.8 (10)
0.3 (15)Points/Play0.3 (4)
353.6 (13)Yards/Gm312.6 (8)
238.2 (16)Pass Yards/Gm216.0 (16)
115.4 (16)Rush Yards/Gm96.6 (4)
5.5 (16)Yards/Play4.9 (7)
6.6 (15)Yards/Pass6.6 (13)
4.2 (20)Yards/Rush3.4 (2)
39.7% (14)3rd Down %31.3% (8)
47.4% (23)Red Zone %57.1% (15)
8 (22)Turnovers5 (23)
6 (3)Sacks11 (12)

Jaguars At Colts Betting Insights

Why The Jaguars Can Cover The Spread

Did you happen to watch the last game these two teams played? All the way back in Week 2? That one ended 24-0 in favor of the Jags, so they have certainly shown they can handle this disastrous Colts team. Matt Ryan has been one of the worst QBs in the NFL thus far, ranking 26th in EPA+CPOE composite. He’s especially prone to taking ugly sacks and throwing off his back foot into coverage when under pressure. Lo and behold, the Jags bring the sixth-highest pressure rate to the table.

Why The Colts Can Cover The Spread

That Week 2 featured some pretty stark mitigating circumstances for the Colts. Dezmon Patton and Ashton Dulin served as the team’s top two wideouts, with Nyheim Hines mixed in for good measure. Michael Pittman and Alec Pierce have returned, the latter finally starting to show the talent that had him as an early draft pick. Trevor Lawrence has regressed to his old turnover-prone ways the past two weeks after a clean start, and the Colts know they need this to keep the divisional hopes reasonable.

Reasons To Bet The Over

The aforementioned 24-0 whitewash may color the market a bit here. As mentioned, the Colts have actual professional receivers available here. Playing in a dome against a team that spent the first few weeks playing efficient passing football, six touchdowns seems like a bar that can be cleared.

Reasons To Bet The Under

Again, the Jags are going to make Ryan’s life difficult. This offense is putrid so far and may be down to a third-string RB if Hines and Jonathan Taylor remain out. The Jags, meanwhile, have struggled to get anything going on the ground, and being a predictable offense against a solid Indy defense could spell trouble.

Jaguars At Colts Matchups To Watch For

Jaguars Interior OL Vs. DeForest Buckner

DeForest Buckner has been an absolute wrecking ball so far. He played by far the biggest role (for the Colts, anyway) in keeping the game close against the Broncos, consistently blowing up plays before they could begin. PFF likes the work of the Jaguars OL so far in pass protection (fourth-best grade), but the interior looks notably weak on paper with only Brandon Scherff projecting as a plus player. The team must keep Buckner at least somewhat in check.

Matt Ryan And Colts OL Vs. Jaguars Pass Rush

Keeping Ryan clean is of paramount importance. He doesn’t have the athleticism to escape the pocket anymore and he has shown a tendency to absorb far too many sacks so far. The Jags will bring plenty of heat, led by Josh Allen, and an inviting target exists in LT Bernhard Raimann. The rookie third-rounder was pressed into service well ahead of schedule and committed several holding penalties in the lucky win against Denver.

Colts Defense Vs. Injury Report

The Colts entered the year with high expectations on defense. Despite a series of injuries, it’s not that unit’s fault the season has gone sideways. They’ve done fine work even against Patrick Mahomes and the Chiefs. Will they remain short-handed here or can they get some of their studs back and go from good to great? Shaq Leonard looms as the most important piece, but pass rush ace Kwity Paye and S Julian Blackmon would help as well. Keep an eye on the injury report.

Final thoughts

This line essentially says the Jags and Colts are roughly equal teams. That seems a little bit insane considering the Jags have been a middle of the pack team thus far, while the Colts have one of the worst offenses in the NFL. Critically, the Jags figure to bring plenty of pressure, Matt Ryan’s big weak point thus far. Frank Reich will need to step it up and do a far better job scheming against this aggressive defense. If Ryan is under pressure in a negative script and/or the Colts injury report looks ugly, consider a wager on the Jaguars at any plus number.

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Mo Nuwwarah Avatar
Written by
Mo Nuwwarah

Mo Nuwwarah got his start in gambling early, making his first sports bet on his beloved Fab Five against the UNC Tar Heels in the 1993 NCAA tournament. He lost $5 to his dad and got back into sports betting years later during a 15-year run in the poker industry. A 2011 journalism graduate from Nebraska-Omaha, he combines those skills with his love of sports and statistics to help bettors make more informed decisions with a focus on pro football, baseball and basketball.

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