Go here for NFL Week 6 odds.
Bettors are getting a good idea of each teams’ strengths and weaknesses now that we are four games into the season. A full month is a decent sample size as we now have some concrete evidence regarding the league’s haves and have-nots. NFL Week 5 odds show some pretty large spreads. This is highlighted by the Bills being -14 at home against the Steelers +14. The Giants and Packers are playing on a neutral field in London, yet Aaron Rodgers’ Green Bay team is a -8 favorite over New York +8. Jacksonville is now highly regarded enough to be a full touchdown favorite, as the Jags are -7 against the Texans +7. Week 5 began with an ugly overtime game between the Colts and Broncos in which Indianapolis won, 12-9. Check out much more on those spreads and all of the Week 5 lines below.
NFL Week 5 odds
View all of the NFL Week 5 odds here and click on the number you like to bet that price now. Pro football point spreads, moneylines and over unders are available to wager on.
NFL Week 5 betting lines
There were several sizable spreads when looking at NFL Week 5 odds Sunday morning. The Buccaneers were -10 against the Falcons +10. Aaron Rodgers and the Packers, who struggled to dismiss the Patriots this past week, are -8 against the Giants +8. Kirk Cousins and the Vikings are -7.5 at home against the Bears +7.5. And the biggest line when looking at NFL Week 5 odds continues to be the Bills -14 at home against rookie Kenny Pickett and the Steelers +14. The ledger continues Sunday with the aforementioned Giants versus Packers clash in London. A Jalen Hurts versus Kyler Murray showdown in the desert will take place as well when the undefeated Eagles -5 visit the Cardinals +5.
Indianapolis Colts (+3) at Denver Broncos
Indianapolis won an all-time snooze-fest of a Thursday night game, toppling the Broncos 12-9 in overtime. The line for this game closed at Colts +3. Matt Ryan and his crew are now 2-3 against the spread this season while the Broncos are an NFL worst 1-4 ATS.
New York Giants at Green Bay Packers
The Giants continued their encouraging start to the Brian Daboll era Sunday with a 20-12 win over the Bears, although both Daniel Jones and Tyrod Taylor suffered in-game injuries that lends some doubt to New York’s quarterback situation as the week begins.
The Packers moved to 3-1 with a harder-than-expected 27-24 overtime win over the Patriots at Lambeau Field, one that saw New England forced to turn to rookie Bailey Zappe under center after Brian Hoyer, already subbing for Mac Jones (ankle), suffered a head injury.
Monday reports on the status both Jones and Taylor are mixed, with the former believed to have a good chance of suiting up for this game and Taylor needing to clear concussion protocol before he can be deemed available.
Jones was especially effective running the ball Sunday before his injury (6-68-2), while Saquon Barkley continued to prove he was all the way back with 146 rushing yards and a pair of catches. However, the matchup against the Packers defense should be a bit tougher, with Green Bay allowing the fifth-fewest yards per game (294.8).
The Pack had their running game working in fine form Sunday (5.7 yards per carry) and Allen Lazard also had the look of a true No. 1 wideout with a 6-116 line. New York could present a stiff challenge through the air (191.3 PYPG allowed), but much more giving on the ground (141.0 RYPG allowed).
The Packers are unsurprisingly expansive favorites of more than a TD to open the week despite the neutral field.
Pittsburgh Steelers at Buffalo Bills
The Steelers blew a double-digit second-half lead to lose the Jets at home on Sunday, but the big story was head coach Mike Tomlin’s decision to insert rookie Kenny Pickett at quarterback to open the second half.
The Bills bounced back from a heartbreaking 21-19 loss to the Dolphins in Week 3 by going into Baltimore and grabbing a win. Buffalo beat the Ravens, 23-20, overcoming a 17-point deficit.
Despite the fact he threw three INTs – one which bounced off Chase Claypool’s hands and the other on a game-ending Hail Mary — there was plenty to like about Pickett’s performance, including the fact he displayed plenty of rapport with fellow rookie George Pickens (6-102) and Pat Freiermuth (7-85). However, if this is indeed his first pro start, it will come in what may be the toughest road environment in the league.
The Bills weren’t quite clicking on all cylinders against the Ravens for four quarters, but given their own tough road conditions, the performance was still a solid one overall. The Steelers defense will certainly present its own challenge, particularly on the pass rushing front, but Pittsburgh is allowing an elevated 383 total yards per game overall.
Irrespective of whether it’s Pickett or Mitch Trubisky under center for the Steelers, oddsmakers don’t seem to give much credence to Pittsburgh. Buffalo is the biggest favorite when looking at NFL Week 5 odds as the Bills are -14.
LA Chargers at Cleveland Browns
The Chargers got back on track at the expense of the Texans on Sunday, getting past Houston by a 34-24 score in a game where Austin Ekeler was finally able to find some running room (5.0 yards per carry) and scored three total touchdowns.
The Browns dropped a winnable game against the Falcons on the road by a 23-20 score, allowing 13 fourth-quarter points and finishing their last two drives with a punt and interception.
Whether the Chargers can keep the running game going behind an offensive line that’s underperformed thus far remains to be seen, but LA will have a decent shot of doing so against a Cleveland squad that’s surrendered 113.3 rushing yards per game and a bloated 5.3 RB yards per carry.
Jacoby Brissett has been adequate in his starting stint thus far, throwing for 830 yards and a 4:2 TD:INT.
However, his shortcomings can certainly emerge at times, and he could have an uphill battle versus a Bolts squad that’s already picked off five passes and recorded 10 sacks.
Oddsmakers are giving the Chargers some credit for turning things around Sunday. LA was a 3-point favorite when looking at NFL Week 5 odds early in the week.
Chicago Bears at Minnesota Vikings
The Bears saw Justin Fields turn in his best passing performance of the season yet in Week 4 against the Giants, but it wasn’t enough in a 20-12 defeat.
The Vikings were able to escape London with a 28-25 win over the Saints on Sunday, with a narrowly missed would-be game-winning field-goal attempt by New Orleans’ Wil Lutz preventing overtime. Justin Jefferson notably got back into the flow of the air attack after a down couple of weeks with a 10-147 line on 13 targets.
Chicago continues to run the most punchless offense in the league despite the signs of improvement Sunday, but they may have a solid chance of carrying over some of their modest Week 4 momentum in this matchup. Minnesota has struggled defensively save for the Week 1 win over Green Bay, now allowing 394.5 total yards per game after the London victory.
On the other side, this could turn into a banner game for Dalvin Cook, as Chicago has been an absolute sieve against the run all season. The Bears have been gashed for an NFL-high 183.3 rushing yards per game and 4.8 RB yards per carry. They’ve been exponentially better versus the pass with the fourth-fewest passing yards per game (168.5) and a 60.4 percent completion rate allowed, but that’s partly the result of the Bears facing the fewest pass attempts (101) of any team that’s played four games.
Following Week 4 results, the Vikings have lost just a half-point from their early projected advantage of -7.
Detroit Lions at New England Patriots
The Lions went into battle against the Seahawks missing three starting offensive players yet nearly pulled off a wild win, falling to Seattle by a 48-45 score in a game during which defense clearly went out the window.
The Patriots were also playing short-handed and at Lambeau Field to boot, but New England managed to almost upending Aaron Rodgers and the Packers before falling by a 27-24 score in overtime. Already down Mac Jones (ankle) coming in, the Pats lost Brian Hoyer to a head injury as well, which forced rookie Bailey Zappe into the game.
The Lions will hope to have at least one of D’Andre Swift (shoulder), Amon-Ra St. Brown (ankle) and DJ Chark (ankle) back for this game, but Jared Goff impressively stepped up despite the multiple absences Sunday. The matchup against the Patriots at Gillette Stadium can always be tricky, however, and New England already comes in yielding just 211.0 passing yards per game and a modest 63.9 percent completion rate.
The Lions continue to get respect from oddsmakers when looking at NFL Week 5 odds, however, as they were less than a field goal underdog on Monday.
Seattle Seahawks at New Orleans Saints
The Seahawks put on an offensive showcase befitting of Russell Wilson’s glory days with the franchise during their 48-45 win over the Lions, with both the passing attack and ground game standing out via multiple impressive individual performances.
The Saints were forced to go into battle against the Vikings in London missing Jameis Winston (back/ankle), Michael Thomas (toe) and Alvin Kamara (ribs), yet they nearly pulled off a win before falling on a missed last-second field-goal try, 28-25.
Geno Smith has been a revelation thus far as Wilson’s successor, throwing for 1,037 yards while posting a 6:2 TD:INT. The veteran has shown excellent rapport with both DK Metcalf and Tyler Lockett, and he’s now facing a Saints defense that, despite yielding just 203.5 passing yards per game, just gave up a 10-147 line to the Vikings’ Justin Jefferson.
The Saints won’t necessarily be in bad shape if they’re forced to go with Andy Dalton under center again for this matchup, and that may well be the case with Winston dealing with multiple injuries. Moreover, even another Kamara absence may not be a back breaker since Mark Ingram could be well equipped to exploit a Seattle defense that’s yielded 154 rushing yards per contest.
The line is still solidly in favor of the Saints despite last weekend’s outcomes. New Orleans was sporting a -5.5 projected advantage when looking at NFL Week 5 odds Monday. That could shrink depending on the public’s faith in Seattle and its perception of injury news throughout the week.
Miami Dolphins at New York Jets
The Dolphins opened the Week 4 slate with a 27-15 loss to the Bengals on Thursday night, a game that saw Tua Tagovailoa’s early-season health saga take an ugly turn with head and neck injuries that required a brief hospitalization and will keep him out of this Week 5 matchup, at minimum.
The Jets welcomed their quarterback into the 2022 regular season on Sunday against the Steelers, and Zach Wilson helped lead a spirited second-half comeback that culminated in New York edging Pittsburgh, 24-20.
Teddy Bridgewater performed admirably for Miami and had the Dolphins close until late in the contest against the Bengals, and he should be a capable fill-in after an extended period to work with the first team in practice. The Jets have played solid defense by the numbers overall, but Tyreek Hill and Jaylen Waddle will represent a test quite like no other for their secondary.
Wilson was solid while working off some rust, throwing for 252 yards and a touchdown and notching a receiving score as well on a trick play. Wilson did throw a pair of INTs, but his deep corps of explosive skill position players could present a problem for a Dolphins secondary that may be down Xavien Howard (groin).
Despite Tagovailoa’s now-confirmed absence and New York’s win, the Dolphins remain 3-point road favorites when looking at NFL Week 5 odds – although this will be an interesting line to keep tabs on as the week unfolds.
Atlanta Falcons at Tampa Bay Buccaneers
The Falcons were able to overcome a mediocre passing performance from Marcus Mariota to get past the Browns by a 23-20 score, but they also lost Cordarrelle Patterson to a knee injury that will keep him out at least the next four games.
The Buccaneers went into their Sunday night battle against the Chiefs better equipped at receiver than in the prior pair of contests, but they still fell to Kansas City by a 41-31 score in a game Tampa Bay’s defense played surprisingly poorly in.
Rookie running back Tyson Allgeier did look very effective in Patterson’s stead during the second half of Sunday’s game, gaining 104 yards on 11 total touches during the game. Backfield mate and fellow rookie Caleb Huntley (10-56-1) also made an impression, but both players could have an uphill battle versus a likely ornery Bucs defense that’s been a bit more vulnerable early this season but still gives up just 106.8 rushing yards per game.
Julio Jones was essentially out the entire second half for the Bucs on Sunday night, while Chris Godwin had an injury scare with his abdomen but did return and logged 10 targets overall. He appears a good bet to be available for this division clash, yet Jones could well need some more time off for his ailing knee. The Falcons will undoubtedly be tested by Brady and whatever weapons he has at his disposal, with the legendary QB coming off a season-high 385-yard, three-TD effort.
The Bucs may not look like themselves yet, but they were still comfortable 8-to-8.5 home favorites when looking at NFL Week 5 odds on Monday.
Tennessee Titans at Washington Commanders
The Titans won’t get many offensive style points for it, but they pulled out a divisional road win with a 24-17 toppling of the Colts on Sunday that saw Ryan Tannehill throw for just 137 yards, albeit with a pair of TD passes.
The Commanders’ post-Week-1 swoon continued Sunday against the Cowboys, with Carson Wentz throwing for just 170 yards and a pair of INTs. Washington’s narrow Week 1 win over the Jaguars is but a distant memory at this point after three straight losses.
One of the encouraging developments for the Titans is the involvement of Derrick Henry as a receiver, with the bruising back now having recorded an 8-91 line on 11 targets in the last two games. Tennessee is also still incorporating Robert Woods fully into the offense as he finishes rounding back into shape following last season’s torn ACL, but they did lose rookie Treylon Burks to a turf toe injury that will reportedly entail a multi-week absence.
The Commanders’ pass protection issues are threatening to derail their season, and Tennessee comes in with 10 sacks over its first four games. Mike Vrabel’s squad has allowed 10 passing touchdowns, yet Wentz has begun to display many of the same warts that ultimately limited his Colts tenure to one season. The Titans notably swept the Colts last season with Wentz at the helm, limiting him to 194 yards in the first meeting and picking him off twice in the second.
Oddsmakers have notably made the Titans a 2.5-point road favorite, certainly showing some diminishing faith in Washington.
Houston Texans at Jacksonville Jaguars
The Texans continued to fight hard under Lovie Smith in Week 4, but they were still overwhelmed by the Chargers, 34-24. One major positive for Houston was the play of rookie running back Dameon Pierce, however; he gained 131 yards on 14 carries, with a big chunk coming on a 75-yard touchdown run.
The Jaguars couldn’t keep their early-season winning streak going, but Jacksonville still gave Philadelphia quite the scare in Doug Pederson’s return to the city. The Jags ultimately dropped a 29-21 decision yet had a chance to drive for a potential tie until a Trevor Lawrence fumble sealed their fate.
Davis Mills continues to show some progress in his second season, but he’s still displaying some struggles with accuracy (62.0 percent completion rate) and turnovers (4 INTs). He’ll have a tough challenge all the way around in this matchup, considering the Jags have already picked off seven passes and recorded nine sacks. Pierce may have a hard time keeping Jacksonville honest also, as the Jags yield only 93.8 rushing yards per game.
Lawrence and the passing attack were far from at their sharpest Sunday, with the second-year signal caller completing less than 50.0 percent of his passes, throwing an interception and taking four sacks. The Texans had been playing solid pass defense prior to running into Justin Herbert on Sunday, but they’re clearly most targetable on the ground (AFC-high 172.0 rushing yards per game allowed), where James Robinson and Travis Etienne could certainly thrive.
In a testament to how far the Jags have come, they’re over a touchdown favorite at one sportsbook as the week begins, noteworthy even if it is versus Houston.
San Francisco 49ers at Carolina Panthers
The 49ers evened their record at 2-2 with a big 24-9 win over the defending champion Rams on Monday night. Jimmy Garoppolo continued to look more comfortable in his new/old starting role, and Jeff Wilson (18-74-1) turned in a solid effort on the ground against a tough defense. A matchup against a Panthers defense that’s been more vulnerable of late with 343 total yards per game allowed in the last three contests.
The Panthers went right back into the loss column in Week 4 after a brief Week 3 reprieve, with the Cardinals coming into town and handing Carolina a 26-16 loss. Baker Mayfield’s struggles continued with a 197-yard, two-interception performance.
Irrespective of what happens Monday night, the Panthers will face a gargantuan task offensively in this game. San Francisco heads into the Week 4 finale allowing an NFL-low 227 total yards per game and a tiny 3.9 yards per play, almost inconceivable figures in the modern NFL, and has already compiled eight sacks in three contests.
Ahead of their MNF contest, the Niners were already 4.5-to-5-point road favorites despite the multi-time-zone travel involved, and that number had unsurprisingly grown to 6.5 by Thursday afternoon.
Dallas Cowboys at Los Angeles Rams
The Cowboys continued to manage well without Dak Prescott (thumb) this past weekend, manhandling the Commanders to the tune of a 25-10 score. Cooper Rush put together another rock-solid performance (223 yards, 2:0 TD:INT), and while the running game couldn’t get going, the defensive effort (two sacks, two INTs) was more than enough to help lead to the easy win.
The Rams emerged from their Monday night divisional battle with the 49ers with a 2-2 record and continued questions about their lackluster offense, which is now averaging only 294 total yards per game. Matthew Stafford threw yet another interception against San Fran, a pick-six no less, and now has to tangle with a Cowboys defense yielding 171.0 passing yards per game and a 61.3 percent completion rate.
Oddsmakers are still affording the hosts plenty of respect, but with Prescott potentially returning for this game and L.A. coming out of the game against San Fran not looking stellar offensively, this number could still shrink some.
Philadelphia Eagles at Arizona Cardinals
It wasn’t easy, but the Eagles continued their early-season success to remain the only undefeated team in the league Sunday, coming back to beat the Jaguars by a 29-21 score. The Cardinals arguably looked the best they have all year while notching a 26-16 win against the Panthers on the road, a game that saw Rondale Moore make his season debut after missing the first three games with a hamstring injury.
What Jalen Hurts couldn’t get done through the air Sunday, Miles Sanders impressively accomplished on the ground with 134 yards and two touchdowns on a season-high 27 carries. Head coach Nick Sirianni has kept his running back’s usage steady thus far and it’s paying off nicely, but the Cards will present a stiff test. Arizona allows only 87.0 rushing yards per game and just limited Christian McCaffrey to 27 yards on eight carries Sunday. Therefore, the pendulum could turn back to Hurts and his stellar receiving duo, as the Cards do concede 255.8 passing yards per contest.
Kyler Murray came out of Sunday’s game with a 96.7 rating and did a nice job spreading the ball around nicely to the likes of Marquise Brown, Zach Ertz, rookie TE Trey McBride and Moore, among others. He still has two more games before DeAndre Hopkins returns from suspension, but he would have really been able to use him for this matchup. Philly has been a nightmare for opposing air attacks, giving up only 177.0 passing yards per game and a league-low 56.4 percent completion rate.
Oddsmakers are showing plenty of faith in the Eagles when looking at NFL Week 5 odds as the 5-to-5.5-point projected edge for Philly is significant for a road team traveling across the country.
Cincinnati Bengals at Baltimore Ravens
The Bengals put together what may have been their most impressive performance of the season yet to open the Week 4 slate on Thursday night, toppling the Dolphins by a 27-15 score in a game during which Tua Tagovailoa was knocked out of action in the second quarter.
The Ravens seemed to have the Bills right where they wanted them before blowing a 20-3 lead in the second half and then passing up a late field goal opportunity that would have given them the lead, only to see Lamar Jackson throw an interception.
Cincy thumped Baltimore in both meetings last season, scoring 41 points apiece in each while limiting the Ravens to just 38 total points. Consequently, they certainly have plenty of positive game film to evaluate, but a Ravens defense already smarting from some collapses and under different leadership with coordinator Mike MacDonald could give a Bengals offensive line that struggles to protect Joe Burrow plenty of trouble with its blitz-heavy approach.
The Ravens will need to solve the Bengals’ defensive puzzle, but Cincinnati notably has applied only modest pressure (seven sacks) early on. However, the Bengals have also forged a 3:4 TD:INT through four games, and they held Jackson to under 50.0 percent passing in the one game he played against them last season. On the ground, J.K. Dobbins scored both a rushing and receiving TD against Buffalo in his second game back from his long injury layoff, but Cincy has given up just 85.8 rushing yards per game and only ceded a 5-22 rushing line to QBs specifically.
The Ravens were standard field-goal home favorites when looking at NFL Week 5 odds early in the week, even though the Bengals will have the rest advantage in this spot.
Las Vegas Raiders at Kansas City Chiefs
The Raiders finally got their first win of the Josh McDaniels Era in Week 4, besting the Broncos by a 32-23 score largely on the back of its defense and a 144-yard, two-touchdown effort from Josh Jacobs.
The Chiefs’ offense looked to be in its Tyreek Hill heyday against what is normally a stingy Bucs defense on Sunday night, with KC notching a 41-31 victory run an impressively well-balanced attack that saw Patrick Mahomes throw for 249 yards and the Clyde Edwards-Helaire-Isiah Pachecho duo compile 155 rushing yards and a TD (CEH).
The Raiders gave up a whopping 89 points in two games against the Chiefs last season, with Mahomes throwing for 664 yards and seven touchdowns without an INT in those games. The perennial Pro Bowler has displayed solid rapport with his two new wideouts, JuJu Smith-Schuster and Marquez Valdes-Scantling, and Travis Kelce continues to look like his All-Pro self, so the pressure on a Raiders defense ranked in the bottom half of the league with 357 total yards per game surrendered is going to be significant.
The Chiefs may find a more potent Raiders team opposing them this season with Davante Adams now helming Vegas’ receiving corps. Derek Carr could also get Hunter Renfrow back for this game after he missed the last pair of contests with a concussion, and in his absence journeyman Mack Hollins has looked like he’ll remain a viable part of the air attack with a 16-257-1 line in the last three contests. KC did allow nearly 400 yards passing to Tom Brady on Sunday night, although part of that was simply through sheer volume with the Bucs in the trail position throughout.
Oddsmakers are unsurprisingly showing the Chiefs plenty of deference at Arrowhead by making them 7-to-7.5-point favorites, but it’s worth noting KC is only 20-21-2 ATS at home since Mahomes took over the starting job in 2018.
How the spreads are changing
Below we will look at how NFL Week 5 odds change in the days leading up to each game. Here are what the spreads looked like on Sunday, October 2 at 9 p.m. ET and on Monday at 9 a.m. ET.
|Date||NFL Odds: October 2 spreads||NFL Odds: October 3 spreads||NFL Odds: October 6 spreads||NFL Odds: October 9 spreads|
|Thursday, October 6||Colts +3 at Broncos -3||Colts +3 at Broncos -3||Colts +3.5 at Broncos -3.5||Colts +3 at Broncos -3|
|Sunday, October 9||Giants +7.5 at Packers -7.5||Giants +8 at Packers -8||Giants +8 at Packers -8||Giants +8 at Packers -8|
|Sunday, October 9||Steelers +14 at Bills -14||Steelers +14 at Bills -14||Steelers +14 at Bills -14||Steelers +14 at Bills -14|
|Sunday, October 9||Seahawks +5 at Saints -5||Seahawks +4 at Saints -4||Seahawks +5.5 at Saints -5.5||Seahawks +5 at Saints -5|
|Sunday, October 9||Chargers -3 at Browns +3||Chargers -3 at Browns +3||Chargers -2.5 at Browns +2.5||Chargers -2 at Browns +2|
|Sunday, October 9||Bears +7 at Vikings -7||Bears +6.5 at Vikings -6.5||Bears +7.5 at Vikings -7.5||Bears +7.5 at Vikings -7.5|
|Sunday, October 9||Lions +2.5 at Patriots -2.5||Lions +2.5 at Patriots -2.5||Lions +3 at Patriots -3||Lions +3.5 at Patriots -3.5|
|Sunday, October 9||Texans +7 at Jaguars -7||Texans +7.5 at Jaguars -7.5||Texans +7 at Jaguars -7||Texans +7 at Jaguars -7|
|Sunday, October 9||Falcons +8.5 at Buccaneers -8.5||Falcons +7.5 at Buccaneers -7.5||Falcons +9.5 at Buccaneers -9.5||Falcons +10 at Buccaneers -10|
|Sunday, October 9||Titans -2.5 at Commanders +2.5||Titans -2.5 at Commanders +2.5||Titans -1.5 at Commanders +1.5||Titans -1 at Commanders +1|
|Sunday, October 9||Dolphins -3 at Jets +3||Dolphins -3 at Jets +3||Dolphins -3.5 at Jets +3.5||Dolphins -3.5 at Jets +3.5|
|Sunday, October 9||49ers -4.5 at Panthers +4.5||49ers -4.5 at Panthers +4.5||49ers -6.5 at Panthers +6.5||49ers -6.5 at Panthers +6.5|
|Sunday, October 9||Cowboys +6 at Rams -6||Cowboys +6 at Rams -6||Cowboys +5.5 at Rams -5.5||Cowboys +5.5 at Rams -5.5|
|Sunday, October 9||Eagles -6 at Cardinals +6||Eagles -6 at Cardinals +6||Eagles -5.5 at Cardinals +5.5||Eagles -5 at Cardinals +5|
|Sunday, October 9||Bengals +3 at Ravens -3||Bengals +3 at Ravens -3||Bengals +3 at Ravens -3||Bengals +3.5 at Ravens -3.5|
|Monday, October 10||Raiders +6.5 at Chiefs -6.5||Raiders +7 at Chiefs -7||Raiders +7 at Chiefs -7||Raiders +7 at Chiefs -7|
Initial lines with spreads, moneylines and totals are from September 28.
|Date||NFL Odds: September 28 spreads||NFL Odds: September 28 moneylines||NFL Odds: September 28 Over Unders|
|Thursday, October 6||Colts +2.5 at Broncos -2.5||Colts +120 at Broncos -140||43|
|Sunday, October 9||Giants +7.5 at Packers -7.5||Giants +280 at Packers -340||41|
|Sunday, October 9||Lions PK at Patriots PK||Lions -110 at Patriots -110||44|
|Sunday, October 9||Steelers +13 at Bills -13||Steelers +575 at Bills -800||47.5|
|Sunday, October 9||Texans +7 at Jaguars -7||Texans +245 at Jaguars -295||43.5|
|Sunday, October 9||Bears +6.5 at Vikings -6.5||Bears +230 at Vikings -275||43|
|Sunday, October 9||Dolphins -6 at Jets +6||Dolphins -250 at Jets +210||45.5|
|Sunday, October 9||Titans PK at Commanders PK||Titans -110 at Commanders -110||42.5|
|Sunday, October 9||Seahawks +6 at Saints -6||Seahawks +210 at Saints -250||41|
|Sunday, October 9||Chargers -1.5 at Browns +1.5||Chargers -125 at Browns +105||48|
|Sunday, October 9||Falcons +9 at Tampa Bay Buccaneers -9||Falcons +330 at Buccaneers -410||47.5|
|Sunday, October 9||49ers -3 at Panthers +3||49ers -165 at Panthers +140||39|
|Sunday, October 9||Cowboys +7 at Rams -7||Cowboys +250 at Rams -300||46|
|Sunday, October 9||Eagles -4 at Cardinals +4||Eagles -195 at Cardinals +165||48.5|
|Sunday, October 9||Bengals +3.5 at Ravens -3.5||Bengals +155 at Ravens -180||48.5|
|Monday, October 10||Raiders +6.5 at Chiefs -6.5||Raiders +245 at Chiefs -295||50.5|