NFL Week 4 Updated Odds: Spreads, Totals, Moneylines, Latest Injuries

Written By Brett Gibbons on October 2, 2022
NFL Week 4

Don’t look now, but we’re already onto Week 4 of the NFL season. The weekend slate offers some serious matchups with real long-term implications. The docket is headlined by the Baltimore Ravens hosting the Buffalo Bills, the Kansas City Chiefs at the Tampa Bay Buccaneers, and capped by Los Angeles Rams at San Francisco 49ers on Monday Night Football. Keep up to date with TheLines all season long for NFL odds and betting strategy.

NFL Week 4 odds

Live NFL News Updates & Betting Angles

Check back all weekend long as TheLines team provides live NFL news and betting analysis for every team as it happens.

Week 4 Player Props

Check out our prop search took below to compare the best player props at every legal US sportsbook. Search for any player on the Week 4 slate and click on the odds you like to be directed to the sportsbook and place your bet!

NFL Week 4 Picks And Predictions

Matt Brown, Stephen Andress and Adam Candee break down the entire Week 4 schedule and offer their best bets and predictions for each game.

Best odds For NFL Week 4

Minnesota Vikings at New Orleans Saints

Kickoff: 9:30 a.m.
TV Channel: NFL Network
Look-ahead line: MIN -1
Current Line: MIN (), O/U ()

Cleveland Browns at Atlanta Falcons

Time of game: 1:00 p.m.
TV Channel: CBS
Look-ahead line: CLE -3
Current Line: CLE (), O/U ()

Washington Commanders at Dallas Cowboys

Time of game: 1:00 p.m.
TV Channel: FOX
Look-ahead line: DAL -2.5
Current Line: DAL (), O/U ()

Seattle Seahawks at Detroit Lions

Time of game: 1:00 p.m.
TV Channel: FOX
Look-ahead line: DET -5.5
Current Line: DET (), O/U ()

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Tennessee Titans at Indianapolis Colts

Time of game: 1:00 p.m.
TV Channel: FOX
Look-ahead line: IND -3.5
Current Line: IND (), O/U ()

Chicago Bears at New York Giants

Time of game: 1:00 p.m.
TV Channel: FOX
Look-ahead line: NYG -3
Current Line: NYG (), O/U ()

Jacksonville Jaguars at Philadelphia Eagles

Time of game: 1:00 p.m.
TV Channel: CBS
Look-ahead line: PHI -7
Current Line: PHI (), O/U ()

New York Jets at Pittsburgh Steelers

Time of game: 1:00 p.m.
TV Channel: CBS
Look-ahead line: PIT -3.5
Current Line: PIT (), O/U ()

Buffalo Bills at Baltimore Ravens

Time of game: 4:05 p.m.
TV Channel: CBS
Look-ahead line: BUF -4
Current Line: BUF (), O/U ()

Los Angeles Chargers at Houston Texans

Time of game: 1:00 p.m.
TV Channel: CBS
Look-ahead line: LAC -7
Current Line: LAC (), O/U ()

Arizona Cardinals at Carolina Panthers

Time of game: 4:05 p.m.
TV Channel: FOX
Look-ahead line: ARI -3
Current Line: CAR (), O/U ()

New England Patriots at Green Bay Packers

Time of game: 4:25 p.m.
TV Channel: CBS
Look-ahead line: GB -6
Current Line: GB (), O/U ()

Denver Broncos at Las Vegas Raiders

Time of game: 4:25 p.m.
TV Channel: CBS
Look-ahead line: LVR -1.5
Current Line: LVR (), O/U ()

Kansas City Chiefs at Tampa Bay Buccaneers

Time of game: 8:20 p.m.
TV Channel: NBC
Look-ahead line: KC -1
Current Line: KC (), O/U ()

Los Angeles Rams at San Francisco 49ers

Time of game: 8:15 p.m.
TV Channel: ESPN
Look-ahead line: SF -1
Current Line: SF (), O/U ()

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Written by
Brett Gibbons

Brett is an avid sports traveler and former Division-I football recruiter for Bowling Green and Texas State. He’s a graduate of BGSU and works as an auditor for Google content curation products. He’s also contributed to Sports Illustrated and Fansided during his young writing career.

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