NFL Week 4 Opening Odds: Buffalo Bills At Baltimore Ravens Betting Lines

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Written By Eli Hershkovich | Last Updated
NFL Look-Ahead Lines

When it comes to betting on Sunday Night Football and look-ahead lines for NFL Week 4 odds, the Ravens vs. Bills represents one of the most intriguing contests on the board. Despite Baltimore’s struggles In Week 1 and 2, these teams were considered two heavyweight AFC contenders entering this season. Sportsbooks had Baltimore as a 1.5-point favorite for this home game against Buffalo on Friday.

The action begins on Sunday, Sept. 29, at 8:20 p.m. ET on NBC and Peacock.

NFL Week 4 Opening odds: bills at Ravens odds

The odds below are the best prices across the best sports betting sites. Find the latest odds below.

Exploring NFL Opening Odds AKA Look-Ahead Lines For Week 4

Most online sportsbooks have NFL look-ahead lines readily available. Customers can wager on Week 4 games before many of the Week 3 games are underway. Granted, betting look-ahead lines can present some risk. Lingering variables, like injuries, can happen in Week 3 that impact the handicap and betting lines for Week 4. Results from previous games can also impact teams’ power ratings while altering point spreads.

When handicapping this AFC tilt, I’d prefer to wait until both teams wrap up their respective Week 3 matchups. Let’s say Lamar Jackson and Co. lose their third straight game to the hands of the Cowboys, and Buffalo starts 3-0.

This line could shift toward a pick’em or potentially favor the Bills if Josh Allen torches Jacksonville’s banged-up secondary on Monday night.

In that case, I would likely bet on Baltimore in a prime buy-low, sell-high spot. But nothing is decided yet, so do not assume the Ravens are worth betting on now. If the opposite occurs, Baltimore could inch closer to -2.5 when the spread reopens.

NFL look-ahead lines: bills at Ravens

Team injuries

Last Updated on 03.14.2025
Player Pos Position Injury Status Snaps/g Snaps Per Game Comment
Baltimore Ravens
There Aren’t Any Injured Players for This Team Currently
Buffalo Bills
Larry Ogunjobi DT Suspension Out 0 Ogunjobi has been suspended for the first six games of the 2025-26 season for violating the league’s performance-enhancing substance policy.
Michael Hoecht OLB Suspension Out 0 Hoecht has been suspended for the first six games of the 2025-26 season for violating the league’s performance-enhancing substance policy.

Head To Head

Last Updated on 09.20.2024
STATS
Ravens logo Ravens BAL
Bills logo Bills BUF
Offense Ranking OFF RNK N/A N/A
Defense Ranking DEF RNK N/A N/A
Offense Net Yards Per Game OFF NET YPG
Defense Net Yards Per Game DEF NET YPG
Passing Yards Per Game PASS YPG
Turnovers Committed Per Game TOC PG
Photo by Associated Press

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