Notable NFL Week 4 Injuries: Chargers QB Justin Herbert, Saints QB Alvin Kamara & Others

Various NFL Week 4 injuries have helped trigger some market movement. One is Chargers quarterback Justin Herbert (ankle), whose status against the Chiefs is unknown after reinjuring his ankle. Saints tailback Alvin Kamara (hip/rib) also surfaced on the injury report midweek. Among the odds for NFL Week 4, let’s look at Herbert and other key names to which bettors should pay attention.

Use our NFL injuries tool below to find the latest update on every player. Just click the plus symbol and scroll at your leisure.

team-by-team injuries for NFL Week 4

Player	Pos Position	Injury	Status	Snaps/g Snaps Per Game	Comment
	Arizona Cardinals
There Aren’t Any Injured Players for This Team Currently
	Atlanta Falcons
There Aren’t Any Injured Players for This Team Currently
	Baltimore Ravens
There Aren’t Any Injured Players for This Team Currently
	Buffalo Bills
Larry Ogunjobi DT Suspension Out 0 Ogunjobi has been suspended for the first six games of the 2025-26 season for violating the league’s performance-enhancing substance policy. Michael Hoecht OLB Suspension Out 0 Hoecht has been suspended for the first six games of the 2025-26 season for violating the league’s performance-enhancing substance policy.
	Carolina Panthers
Jonathon Brooks RB Knee Out 0 Brooks is recovering form a torn ACL injury and has been placed on the PUP list. He will miss the entire 2025-26 season.
	Chicago Bears
There Aren’t Any Injured Players for This Team Currently
	Cincinnati Bengals
There Aren’t Any Injured Players for This Team Currently
	Cleveland Browns
Deshaun Watson QB Ankle Out 0 Watson has suffered a torn Achilles and could miss the entire 2025-26 season. Ja’Seem Reed WR Undisclosed Out 0 Reed has been placed on the injured reserve list and will miss the 2025-26 season. Jeremiah Owusu-Koramoah LB Neck Out 0 Brooks is recovering form a neck injury and has been placed on the PUP list. He will miss the entire 2025-26 season.
	Dallas Cowboys
There Aren’t Any Injured Players for This Team Currently
	Denver Broncos
There Aren’t Any Injured Players for This Team Currently
	Detroit Lions
Alim McNeill DL Knee Out 0 McNeill suffered a torn ACL and could miss the start of the 2025-26 season. Malcolm Rodriguez LB Knee Out 0 Rodriguez suffered a torn ACL and could miss the start of the 2025-26 season.
	Green Bay Packers
Christian Watson WR Knee Out 0 Watson is recovering from a torn ACL and will miss the start of the 2025 season.
	Houston Texans
Brevin Jordan TE Knee Out 0 Jordan suffered a torn ACL and could miss the start of the 2025-26 season. Tank Dell WR Knee Out 0 Dell suffered a dislocated knee and a torn ACL. He will miss the start of the 2025-26 season.
	Indianapolis Colts
There Aren’t Any Injured Players for This Team Currently
	Jacksonville Jaguars
There Aren’t Any Injured Players for This Team Currently
	Kansas City Chiefs
BJ Thompson DE Undisclosed Out 0 Thompson is dealing with an undisclosed injury and has been placed on the non-football injury list. Jared Wiley TE Knee Out 0 Wiley is recovering from a torn ACL and could miss the start of the 2025-26 season. Keaontay Ingram RB Undisclosed Out 0 Ingram has been placed on injured reserve and will miss the entire 2025-26 season.
	Las Vegas Raiders
There Aren’t Any Injured Players for This Team Currently
	Los Angeles Chargers
There Aren’t Any Injured Players for This Team Currently
	Los Angeles Rams
Drake Stoops WR Suspended Out 0 Stoops has been suspended for the first two games of the 2025-26 season for violating the league’s performance-enhancing substance policy.
	Miami Dolphins
There Aren’t Any Injured Players for This Team Currently
	Minnesota Vikings
There Aren’t Any Injured Players for This Team Currently
	New England Patriots
Stefon Diggs WR Knee Out 0 Diggs suffered a torn ACL and could miss the start of the 2025-26 season.
	New Orleans Saints
There Aren’t Any Injured Players for This Team Currently
	New York Giants
Victor Dimukeje OLB Pectoral Out 0 Dimukeje has suffered a torn pectoral and will miss the start of the 2025-26 regular season.
	New York Jets
There Aren’t Any Injured Players for This Team Currently
	Philadelphia Eagles
Nakobe Dean LB Knee Out 0 Dean is recovering from a torn patellar tendon and could miss the start of the 2025-26 season.
	Pittsburgh Steelers
There Aren’t Any Injured Players for This Team Currently
	San Francisco 49ers
There Aren’t Any Injured Players for This Team Currently
	Seattle Seahawks
There Aren’t Any Injured Players for This Team Currently
	Tampa Bay Buccaneers
There Aren’t Any Injured Players for This Team Currently
	Tennessee Titans
Julius Wood S Suspended Out 0 Wood has been suspended for the first six games of the 2025-26 season for violating the league’s performance-enhancing substance policy. Lloyd Cushenberry III C Achilles Out 0 Cushenberry III has suffered a torn Achilles and will miss the start of the 2025-26 season.
	Washington Commanders
Sam Cosmi G Knee Out 0 Cosmi suffered a torn ACL and is expected to miss the start of the 2025-26 season.

chargers qb justin herbert

On Monday, Herbert underwent an MRI on his ankle, which showed his was “progressing,” according to Chargers head coach Jim Harbaugh. He’s been limited over the first two days of practice.

After Herbert played through the injury against the Steelers, the betting market expects him to do so again. Los Angeles was an eight-point underdog versus the defending Super Bowl champs earlier in the week, but it’s now priced at the key number of a touchdown. Remember that the Chargers could be without starting tackles Rashawn Slater (pec) and Joe Alt (MCL sprain).

Saints running back Alvin Kamara

Kamara was added to Wednesday’s injury report after dealing with Week 3 hip and rib injuries. He practiced on Thursday in a limited fashion.

Granted, the market has shown interest in the Falcons in their three contests. Couple that with the notion that running backs aren’t typically worth much to the point spread, and there’s no direct correlation between Kamara’s injuries and Atlanta rising from -1.5 to -2/2.5. Hence, Kamara’s situation differs from Herbert’s regarding the market and NFL injuries.

It’s worth noting that Kamara played through a rib cartilage fracture in Week 1 of the 2022 campaign.

Texans Injuries

Collins (hamstring), the Texans’ No. 1 wide receiver, was tacked onto Thursday’s injury report. Collins was deemed a limited participant, so his status for Sunday’s tilt against the Jaguars is unknown. No. 3 wide receiver Tank Dell (chest) and tailback Joe Mixon (ankle) also failed to suit up in either practice.

Following Jacksonville’s blowout loss in Buffalo, Houston was adjusted from -5.5 to -7. The market responded by betting the Jaguars down to +6.5 on Wednesday. These injuries have certainly impacted the number ever since, with some books listing Trevor Lawrence and Co. as a six-point underdog.

Before Week 3, Collins was pegged with hip/foot injuries but played through them. Read more about this matchup in my NFL Week 4 best bets column.

Bears WR Rome Odunze

Odzune, the Bears’ rookie wide receiver, was included in Thursday’s injury report with a hip injury. Fantasy injury analyst Jeff Mueller stated, “Hopefully, it’s not hip flexor/soft tissue, which would come with high reinjury risk in-game.”

Regardless of Odunze’s impending status, Chicago has been bet up to a field-goal favorite against Los Angeles. With veteran wideout Keenan Allen (heel) expected to return, the Bears should be well-suited to attack Los Angeles’ depleted defense.

Lions TE Sam LaPorta

LaPorta was initially carted off the field against Arizona with an ankle sprain before returning. However, his snaps decreased substantially in the second half. But on Friday, LaPorta returned to practice, so it appears he’s on track to take the field against the Seahawks on Monday night.

Like other NFL injuries, LaPorta’s presence is not substantial enough to affect the spread. Nevertheless, Seattle’s defense has struggled to defend tight ends, surrendering the fourth-most targets per game to the position.

For reference, the Lions opened as 4.5-point home favorites before the line shrunk to -3.5.

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