NFL Week 2 Preview: Arizona Cardinals At Las Vegas Raiders Odds

Written By Brett Gibbons on September 17, 2022
Cardinals Raiders odds

The Arizona Cardinals (0-1) are underdogs as they visit the Las Vegas Raiders (0-1) at 4:25 p.m. ET on Sunday, Sept. 18. This is the first regular season game at Allegiant Stadium in Las Vegas of the season. Cardinals – Raiders odds sit at Raiders on the moneyline and the point total is set at .

Below, we’ll look at Cardinals at Raiders odds and game preview. We’ll cover injuries, line movement, and matchups. Stick with TheLines all season long for weekly NFL odds and game previews.

Cardinals At Raiders Betting Odds

To place a bet, click on the odds in the table below. You can toggle between spread, totals, and moneyline in the dropdown menu.

Cardinals At Raiders Player Props

Search for Cardinals or Raiders player props in the NFL Player Prop Search Tool below. Simply type the player’s name into the search bar.

Cardinals At Raiders Betting News & Angles

Cardinals At Raiders Injury Report

PlayerPositionInjuryWedThuFriGame Status
Andy IsabellaWRBackDNPDNPOut
Rondale MooreWRHamstringDNPDNPOut
Jalen ThompsonFSToeDNPLPQuestionable
J.J. WattDECalfDNPLPQuestionable
Trayvon MullenCBToeLPLPQuestionable
Justin PughGNeckLPLPQuestionable
PlayerPositionInjuryWedThuFriGame Status
Brandon BoldenRBHamstringDNPDNPDNPDoubtful
Nate HobbsCBBackFPFPFP(-)
Andre JamesCConcussionDNPDNPDNPOut
Tre'von MoehrigFSHipDNPDNPDNPOut
Denzel PerrymanMLBAnkleDNPDNPDNPOut
Sam WebbCBAnkle(-)LPFP(-)

Cardinals offense vs. Raiders defense

Cardinals OStats (Rank)Raiders D
21.0 (15th)Points/Gm24.0 (22nd)
0.333 (20th)Points/Play0.369 (22nd)
282.0 (24th)Yards/Gm355.0 (16th)
179.0 (26th)Pass Yards/Gm279.0 (25th)
103.0 (16th)Rush Yards/Gm76.0 (8th)
4.5 (27th)Yards/Play5.5 (16th)
5.4 (28th)Yards/Pass8.1 (29th)
4.7 (15th)Yards/Rush2.5 (1st)
25.0% (28th)3rd Down %42.9% (18th)
100% (t-1st)Red Zone TD %66.7% (17th)
0.0 (t-1st)Turnovers0.0 (t-26th)
3.0 (21st)Sacks0.0 (t-30th)

Raiders offense vs Cardinals defense

Raiders OStats (Rank)Cardinals D
19.0 (22nd)Points/Gm44.0 (32nd)
0.339 (17th)Points/Play0.667 (32nd)
320.0 (21st)Yards/Gm488.0 (31st)
256.0 (12th)Pass Yards/Gm360.0 (32nd)
64.0 (29th)Rush Yards/Gm128.0 (22nd)
5.7 (13th)Yards/Play7.4 (32nd)
8.0 (10th)Yards/Pass9.2 (31st)
4.9 (10th)Yards/Rush4.7 (19th)
45.5% (11th)3rd Down %62.5% (29th)
66.7% (t-11th)Red Zone TD %100% (t-23rd)
3.0 (27thTurnovers1.0 (t-14th)
6.0 (30th)Sacks0.0 (30th)

Cardinals At Raiders Betting Insights

Why The Cardinals Can Cover The Spread

Arizona’s high-powered offense was ineffective for most of their opening week game against the Chiefs. However, they roster dynamic QB Kyler Murray and Marquise Brown, who Murray picked right back up with after his days at Oklahoma. This is an offense we know is effective, particularly against a Raiders defense that lost a lot of pieces in the offseason.

It’ll take more aggressive play calling from Kliff Kingsbury to use his athletes out wide. 5.5 points is a steep margin for two teams who aren’t ranked terribly dissimilar. The Raiders are no strangers to track meets, but if the Cardinals can get into a shootout, they are likely to cover.

Why The Raiders Can Cover The Spread

Murray and Brown aren’t the only pair of college teammates reunited in 2022– Derek Carr and Davante Adams proved to be an effective pair, with Adams hauling in 10 receptions for 141 yards and a touchdown. They face a Cardinals defense that was torched for five touchdowns against the Chiefs, a team with no identity at receiver.

Having a go-to for Las Vegas is a major matchup advantage. Darren Waller also gets an opportunity to build upon a disappointing Week 1. Last week, the Cardinals allowed more than 120 receiving yards to the Chiefs’ Travis Kelce. Waller dropped a TD opportunity and hauled in four passes for 79 yards.

The Raiders have the advantage in the pair of defenses and should be able to move the ball in this game.

Reasons To Bet The Over

Two potent offenses mixed with a bad defense and a mediocre defense leads to points. Las Vegas picked up the 13th-most yards per play (5.7) while Arizona allowed the most yards per play (7.1!) last week. The Raiders should take advantage of the Cardinals’ secondary that was torched without Patrick Mahomes having a star receiver.

Both teams turn to their franchise QB when games are close. In their first game under Josh McDaniels, the Raiders threw the ball with the second-highest frequency in the NFL (76.8%). The Raiders finished their game within a score of the Chargers last week, proving that McDaniels will throw the ball when the game hangs in the balance. The Cardinals attempted a pass on 65.1% of plays last week in a positive game script, as they were trailing.

If this game remains close down the stretch, these teams are going to air the ball out.

Reasons To Bet The Under

Betting the over relies on a positive game script for this game. With a soft defense across from them, it’s not out of the realm of possibility that the Raiders run the ball, control the clock, and get up big early. In New England, McDaniels led a run-heavy offense dependent on his personnel.

The other possibility arises that the Cardinals defense isn’t as bad as advertised in Week 1. 51.5 points is one of the week’s highest totals, making it harder to achieve.

Cardinals At Raiders props: Matchups To Watch For

Davante Adams vs. Cardinals secondary: Despite the Chiefs not having a go-to receiver like Tyreek Hill, the Cardinals gave up 360 passing yards and five touchdowns in Week 1. Conversely, Adams was a force to be reckoned with against the Chargers. He seamlessly connected with Carr for over 140 yards and a TD. Adams has dominated opposing secondaries for years and this week may not be any different.

  • Receptions: Over/Under / ()

Maxx Crosby vs. Kyler Murray: Keeping Murray bottled up is crucial for the Raiders defense this week. Last season, Maxx Crosby recorded eight sacks, bringing his career total to 25. Murray was pressured on 68.2% of dropbacks last week against the Chiefs due to a porous offensive line.

Darren Waller vs. Cardinals linebackers/safeties: Aside from bleeding yards through the air to receivers, the Cardinals were torched by Kelce (8-121-1). Waller just inked a three-year, $51 million extension a few weeks ago and followed it up with four receptions on six targets. As mentioned, he dropped a potential TD at the goalline. This week, he’ll have another opportunity to rack up yards.

  • Receiving Yards: Over/Under / ()

Final Thoughts

Despite getting blasted by the Chiefs 44-21 last week, the Cardinals are likely to take action this week with a 5.5 point gap. The past few years saw Arizona get off to hot starts followed up by late-season meltdowns. Las Vegas is a notably tough place to play, though.

With their defense-optional showing in Week 1, we could also see action come in on over the points. Neither number should see a ton of movement, as they remained relatively statue through the first half of the week.

Neither team covered its Week 1 spread. While the Cardinals went over their point total in their game, the Raiders game went under.

Best of luck handicapping Cardinals Raiders odds.

Follow TheLines on Twitter

Brett Gibbons Avatar
Written by
Brett Gibbons

Brett is an avid sports traveler and former Division-I football recruiter for Bowling Green and Texas State. He’s a graduate of BGSU and works as an auditor for Google content curation products. He’s also contributed to Sports Illustrated and Fansided during his young writing career.

View all posts by Brett Gibbons