NFL Week 16 Odds | Point Spreads, Moneylines And Totals For Every Game

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Written By Eli Hershkovich | Last Updated
NFL Week 16 odds

The long holiday weekend will be filled with football action including a jam-packed slate on Christmas Eve and three games on Christmas Day. NFL Week 16 odds are available to wager on now including point spreads, moneylines and totals. Some of the top games on the Week 16 schedule include the Dallas Cowboys at Miami Dolphins and the Baltimore Ravens at San Francisco 49ers.

Other important contests include the New Orleans Saints at LA Rams and the Cleveland Browns at Houston Texans. View all Week 16 NFL odds below.

NFL Week 16 odds

Compare lines for upcoming pro football games below. View NFL Week 16 odds including point spreads, moneyline betting and totals.

The week kicked off with the New Orleans Saints battling the LA Rams on Thursday Night Football. Here is a look at what the lines were for that tilt.

  • Point Spread: Saints (+4.5) at Rams (-4.5)
  • Moneyline: Saints (+166) at Rams (-198)
  • Total: 44.5

The Rams beat the Saints, 30-22, as the game went over the 44.5 point total.

NFL Week 16 betting lines

Getting a good number is paramount when betting on the NFL. Let’s take a deeper dive into these key betting games.

Bengals (-2) at Steelers (+2)

Cincinnati overcame a double-digit fourth-quarter deficit versus Minnesota, yet Pittsburgh was dealt a two-possession loss in Indianapolis. The Mike Tomlin “rah-rah” situational spot didn’t cash in, and the Steelers have plenty of work to do for a playoff spot.

The motivation spot sides with the Bengals. Not only are they looking to continue their push for an AFC wild-card spot, but they’re also eyeing revenge after falling to the Steelers in Week 12.

Moreover, Jake Browning has accrued the second-most adjusted EPA per play among qualified quarterbacks since Week 13. He’s only behind Brock Purdy in that department.

Lions (-3) at Vikings (+3)

Although Detroit has essentially clinched the NFC North title at this juncture, Dan Campbell’s team can seal the deal with an outright victory. Nevertheless, Minnesota will also be fighting for its postseason life. Vikings coach Kevin O’Connell must get consistent QB play from Nick Mullens, as the Lions’ secondary remains their biggest liability.

Browns (+2) Texans (-2)

Here’s another game with massive playoff implications. Both teams are in the AFC wild-card hunt, with Houston currently on the outside looking in. Should Texans rookie QB C.J. Stroud return from a concussion, Cleveland’s defense — which has performed in pedestrian-like fashion on the road — could be in trouble.

On top of that, the Browns have manufactured their fair share of positive variance, going 5-0 in matchups decided by a field goal or less. Therefore, their market rating may be slightly inflated, thanks to close-game luck.

Cowboys (+1.5) at Dolphins (-1.5)

Although the betting market moved against Miami in Week 15, with Tyreek Hill (ankle) on the sidelines, Miami still blitzed the Jets by 30 points. Meanwhile, Dallas was routed by the Bills. Hill will reportedly be ready for this contest, but I’d expect Dak Prescott & Co. to bounce back against the banged-up Dolphins.

How NFL Week 16 odds are changing

Below we will look at how NFL Week 16 odds change in the days leading up to kickoff of each game.

MatchupPoint SpreadTotalMoneyline
New Orleans Saints at LA RamsSaints (+4) at Rams (-4)44.5Saints (+164) at Rams (-196)
Cincinnati Bengals at Pittsburgh SteelersBengals (+1.5) at Steelers (-1.5)39.5Bengals (-104) at Steelers (-112)
Buffalo Bills at LA ChargersBills (-9.5) at Chargers (+9.5)40.5Bills (-510) at Chargers (+390)
Indianapolis Colts at Atlanta FalconsColts (+1.5) at Falcons (-1.5)43.5Colts (-102) at Falcons (-116)
Green Bay Packers at Carolina PanthersPackers (-4.5) at Panthers (+4.5)36.5Packers (-225) at Panthers (+188)
Cleveland Browns at Houston TexansBrowns (+1.5) at Texans (-1.5)41.5Browns (-102) at Texans (-116)
Detroit Lions at Minnesota VikingsLions (-3) at Vikings (+3)45Lions (-154) at Vikings (+130)
Washington Commanders at New York JetsCommanders (+3) at Jets (-3)39.5Commanders (+126) at Jets (-148)
Seattle Seahawks at Tennessee TitansSeahawks (-1.5) at Titans (+1.5)43Seahawks (-126) at Titans (+108)
Jacksonville Jaguars at Tampa Bay BuccaneersJaguars (-2.5) at Buccaneers (+2.5)44Jaguars (-144) at Buccaneers (+122)
Arizona Cardinals at Chicago BearsCardinals (+3.5) at Bears (-3.5)43.5Cardinals (+146) at Bears (-174)
Dallas Cowboys at Miami DolphinsCowboys (+1.5) at Dolphins (-1.5)52.5Cowboys (-104) at Dolphins (-112)
New England Patriots at Denver BroncosPatriots (+5.5) at Broncos (-5.5)36.5Patriots (+198) at Broncos (-240)
Las Vegas Raiders at Kansas City ChiefsRaiders (+10.5) at Chiefs (-10.5)42Raiders (+385) at Chiefs (-500)
New York Giants at Philadelphia EaglesGiants (+10.5) at Eagles (-10.5)43.5Giants (+440) at Eagles (-590)
Baltimore Ravens at San Francisco 49ersRavens (+4.5) at 49ers (-4.5)45.5Ravens (+164) at 49ers (-196)

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