NFL Week 15 Betting Preview: San Francisco 49ers at Seattle Seahawks

Written By Eli Hershkovich on December 15, 2022 - Last Updated on December 16, 2022
49ers Seahawks Odds

The San Francisco 49ers face off against the Seattle Seahawks on Thursday, Dec. 15 at 8:15 p.m. ET. This west coast affair, which is the first contest on NFL Week 15 odds board, showcases 49ers Seahawks odds with a spread of San Francisco and on the moneyline. The total is set at .

In this post, we’ll dive into everything you need to know before placing a bet on Thursday Night Football odds, including matchups, key metrics, and the best available odds.

49ers Seahawks Odds: Spread, Moneyline, Over/Under

When using the 49ers Seahawks odds table above, click the dropdown menu to switch to moneylines or over/unders. 

Betting on the point spread is when you wager on how many points a team will win or lose by. A “plus” sign in front of the spread is the underdog, and a “minus” sign is the favorite. The 49ers need to win by four points or more if you bet on them against the spread, as they’re priced as a cheap 3.5-point road favorite at most shops. Conversely, a spread bet on the Seahawks would need Seattle to lose by three points or win outright.

The total is the number of combined points that the two teams will score. Bettors can bet “over” or “under” on how many total points will be scored in the game.

  • Join our NFL Discord channel to receive an immediate notification when any of our staff members places a bet, including on the 49ers – Seahawks odds. Sign up under the #roles server.

49ers Seahawks Odds: Player Props

In the props tool search bar, type in a team or player and hit enter. You’ll see the various proposition bets offered by leading online sportsbooks. 

This is a valuable tool that allows bettors to compare odds and stats when considering a prop bet.

49ers at Seahawks: Betting News

Seattle has accrued 70% of the spread handle while San Francisco has tallied 64% of the handle, respectively. This data comes from BetMGM Sportsbook, which is trading the 49ers at . Additional updates on the 49ers – Seahawks odds can be found below.

49ers at Seahawks Weather

Dry conditions (scattered clouds) and 5 mph winds are expected at Lumen Field on Thursday.

49ers at Seahawks Injury Report

San Francisco Injuries

PlayerPos.InjuryStatus
Deebo SamuelWRAnkleOut
Brock PurdyQBObliqueQuestionable
Samuel WomackCBConcussionOut
Tarvarius MooreDBKneeOut
Dontae JohnsonCBKneeOut
Ambry ThomasCBAnkleQuestionable

Seattle Injuries

PlayerPos.InjuryStatus
Ryan NealSSKneeQuestionable
Al WoodsDTAchillesQuestionable
DeeJay DallasRBAnkleQuestionable
Joey BlountFSBackQuestionable
Tre BrownCBIllnessQuestionable

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49ers Offense Vs. Seahawks Defense

49ers OffenseStats (Rank)Seahawks Defense
24.4 (8)Points/Gm25.7 (30)
0.4 (2)Points/Play0.4 (14)
361.5 (9)Yards/Gm378.7 (28)
230.8 (13)Pass Yards/Gm218.2 (18)
130.6 (9)Rush Yards/Gm160.5 (31)
5.8 (8)Yards/Play5.6 (18)
7.3 (5)Yards/Pass6.7 (17)
4.5 (14)Yards/Rush4.9 (28)
45.2% (5)3rd Down %44.9% (28)
54.5% (15)Red Zone %60.5% (25)
15 (11)Turnovers21 (5)
23 (5)Sacks34 (10)

Seahawks Offense Vs. 49ers Defense

Seahawks OffenseStats (Rank)49ers Defense
26.3 (6)Points/Gm15.2 (1)
0.4 (2)Points/Play0.3 (1)
355.2 (13)Yards/Gm286.8 (1)
244.1 (9)Pass Yards/Gm211.8 (12)
111.2 (21)Rush Yards/Gm75.1 (1)
6.0 (4)Yards/Play4.8 (1)
7.4 (4)Yards/Pass6.1 (7)
4.7 (8)Yards/Rush3.4 (1)
43.2% (8)3rd Down %38.4% (12)
51.2% (23)Red Zone %53.6% (11)
19 (26)Turnovers21 (5)
34 (20)Sacks36 (8)

TheLines Podcast: NFL Week 15 Betting Breakdown

For the audio-only version, subscribe to TheLines on Apple Podcasts.

49ers Seahawks Odds: Betting Insights

Which Team Will Cover The Spread?

After finishing with the fourth-highest Dropback EPA in Week 14, the betting market has fallen in love with 49ers rookie QB Brock Purdy. As San Francisco aims to clinch the NFC West with a victory, we’ve seen the spread shift above the key number of a field goal.

Nevertheless, Kyle Shanahan’s offense employs the league’s 10th-highest rushing rate, and that will likely remain the case with Purdy dealing with an oblique injury. Shanahan hasn’t declared Purdy as the starter for this week, yet he did note that Purdy wouldn’t worsen his injury by suiting up in Seattle.

Keep in mind, Seattle is allowing the 12th-lowest Rushing Success Rate across the NFL. For context, a play is successful if teams produce:

  • 50 percent of the yards needed to move the chains on first down
  • 70 percent of yards to gain on second down
  • 100 percent of yards to gain on third or fourth down

Hence, the 49ers may not be as efficient on the ground as one would initially expect. But Al Woods’ absence on the Seahawks’ defensive front hurts that notion.

On the flip side, Geno Smith is up against arguably one of the league’s premier defenses, especially against the pass. While he’s exceeded expectations in his ninth season as a pro, he may not be as fortunate this time against DeMeco Ryans’ pressure-heavy unit.

Will The Total Go Over Or Under?

If you couldn’t tell from the context above, expect both offenses to struggle. Couple that with San Francisco’s tempo ranking No. 25 in neutral situations (per Football Outsiders), and I’d anticipate a methodical pace from Shanahan with his rookie in a hostile environment as well.

Final Thoughts

I bet under 43.5, which you’ll find in our aforementioned Discord betting channel. Play it down to 43. Good luck with your own wagers on 49ers Seahawks odds.

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