NFL Week 12 Rundown: Lines, Spreads, Over/Unders, Injury News

Written By Brett Gibbons on November 28, 2021
NFL Week 12 odds

Find the most up-to-date NFL Week 12 odds, along with injury and betting news below. This week’s slate is headlined by Browns at Ravens, Rams at Packers, and the traditional Thanksgiving Day lineup. The Vikings and 49ers face off for a playoff position and 10 teams are pit against division rivals.

Teams on bye this week include the Arizona Cardinals and the Kansas City Chiefs.

Pittsburgh Steelers at Cincinnati Bengals

Kickoff: 1:00 p.m. ET
TV Channel: CBS
Look-ahead line: CIN -3.5
Current Line: CIN (), O/U ()

Pittsburgh vs. Cincinnati key injuries

  • Steelers vs. Bengals Week 12 injury report

Steelers vs. Bengals Week 12 betting preview

Bengals vs. Steelers betting news & angles

New York Jets at Houston Texans

Time of game: 1:00 p.m. ET
TV Channel: CBS
Look-ahead line: HOU -2.5
Current Line: HOU (), O/U ()

N.Y. Jets at Houston key injuries

  • Jets vs. Texans Week 12 injury report

Texans vs. Jets Week 12 betting preview

Jets vs. Texans betting news & angles

Tampa Bay Buccaneers at Indianapolis Colts

Time of game: 1:00 p.m. ET
TV Channel: FOX
Look-ahead line: TB -3.5
Current Line: TB (), O/U ()

Tampa Bay at Indianapolis key injuries

  • Buccaneers vs. Colts Week 12 injury report

Colts vs. Buccaneers Week 12 betting preview

Buccaneers vs. Colts betting news & angles

Atlanta Falcons at Jacksonville Jaguars

Time of game: 1:00 p.m. ET
TV Channel: CBS
Look-ahead line: ATL -1
Current Line: ATL (), O/U ()

Atlanta at Jacksonville key injuries

  • Falcons vs. Jaguars Week 12 injury report

Jaguars vs. Falcons Week 12 betting preview

Falcons vs. Jaguars betting news & angles

Carolina Panthers at Miami Dolphins

Time of game: 1:00 p.m. ET
TV Channel: FOX
Look-ahead line: CAR -1.5
Current Line: CAR (), O/U ()

Carolina at Miami key injuries

  • Panthers vs. Dolphins Week 12 injury report

Dolphins vs. Panthers Week 12 betting preview

Panthers vs. Dolphins betting news & angles

Tennessee Titans at New England Patriots

Time of game: 1:00 p.m. ET
TV Channel: CBS
Look-ahead line: NE -3
Current Line: NE (), O/U ()

Tennessee at New England key injuries

  • Titans vs. Patriots Week 12 injury report

Patriots vs. Titans Week 12 betting preview

Titans vs. Patriots betting news & angles

Philadelphia Eagles at New York Giants

Time of game: 1:00 p.m. ET
TV Channel: FOX
Look-ahead line: PHI -2.5
Current Line: PHI (), O/U ()

Philadelphia at N.Y. Giants key injuries:

  • Eagles vs. Giants Week 12 injury report

Giants vs. Eagles Week 12 betting preview

Eagles vs. Giants betting news & angles

Los Angeles Chargers at Denver Broncos

Time of game: 4:05 p.m. ET
TV Channel: CBS
Look-ahead line: LAC -2
Current Line: LAC (), O/U ()

L.A. Chargers at Denver key injuries

  • Chargers vs. Broncos Week 12 injury report

Broncos vs. Chargers Week 12 betting preview

Chargers vs. Broncos betting news & angles

Los Angeles Rams at Green Bay Packers

Time of game: 4:25 p.m. ET
TV Channel: FOX
Look-ahead line: GB -1.5
Current Line: GB (), O/U ()

L.A. Rams at Green Bay key injuries

  • Rams vs. Packers Week 12 injury report

Packers vs. Rams Week 12 betting preview

Rams vs. Packers betting news & angles

Minnesota Vikings at San Francisco 49ers

Time of game: 4:25 p.m. ET
TV Channel: FOX
Look-ahead line: SF -2.5
Current Line: SF (), O/U ()

Minnesota vs. San Francisco key injuries

  • Vikings vs. 49ers Week 12 injury report

49ers vs. Vikings Week 12 betting preview

Vikings vs. 49ers betting news & angles

Cleveland Browns at Baltimore Ravens

Time of game: 8:20 p.m. ET
TV Channel: NBC
Look-ahead line: BAL -4.5
Current Line: BAL (), O/U ()

Cleveland vs. Baltimore key injuries

  • Browns vs. Ravens Week 12 injury report

Ravens vs. Browns Week 12 betting preview

Browns vs. Ravens betting news & angles

Seattle Seahawks at Washington Football Team

Time of game: 8:15 p.m. ET
TV Channel: ESPN
Look-ahead line: SEA -3.5
Current NFL Week 12 Odds: SEA (), O/U ()

Seattle vs. Washington injuries

  • Seahawks vs. Football Team Week 12 injury report

Washington vs. Seahawks Week 12 betting preview

Seahawks vs. Washington betting news & angles

Keep up-to-date with theLines for NFL Week 12 odds and NFL previews all season long.

Brett Gibbons Avatar
Written by
Brett Gibbons

Brett is an avid sports traveler and former Division-I football recruiter for Bowling Green and Texas State. He’s a graduate of BGSU and works as an auditor for Google content curation products. He’s also contributed to Sports Illustrated and Fansided during his young writing career.

View all posts by Brett Gibbons