NFL Week 11 Odds: Pro Football Spreads, Moneylines, Over Unders

Written By Juan Carlos Blanco on November 21, 2021
NFL Week 11 odds spreads lines

The weekend before Thanksgiving is always a key stretch on the NFL calendar. That is the case this year as well when looking at NFL Week 11 odds. The slate features matchups like Colts at Bills, Bengals at Raiders, Cowboys at Chiefs, Cardinals at Seahawks and Steelers at Chargers. Lines for each game are available to bet on at top sportsbooks.

NFL Week 11 odds

The best NFL Week 11 odds for betting are shown below and you can click on the pro football point spread, moneyline or totals price you like to wager now.

How the lines are changing

Here, first, are the NFL Week 11 odds from Nov. 10. We will also show how the NFL Week 11 spreads are changing below.

  • New England Patriots -4 at Atlanta Falcons +4
  • Green Bay Packers -2 at Minnesota Vikings +2
  • Indianapolis Colts +6.5 at Buffalo Bills -6.5
  • New Orleans Saints (PK) at Philadelphia Eagles (PK)
  • Houston Texans +10 at Tennessee Titans -10
  • San Francisco 49ers -5.5 at Jacksonville Jaguars +5.5
  • Washington Football Team +1.5 at Carolina Panthers -1.5
  • Miami Dolphins -2.5 at New York Jets +2.5
  • Detroit Lions +10 at Cleveland Browns -10
  • Baltimore Ravens -6 at Chicago Bears +6
  • Cincinnati Bengals (PK) at Las Vegas Raiders (PK)
  • Arizona Cardinals +1 at Seattle Seahawks -1
  • Dallas Cowboys +2.5 at Kansas City Chiefs -2.5
  • Pittsburgh Steelers +3.5 at LA Chargers -3.5
  • New York Giants +12 at Tampa Bay Buccaneers -12

Here are updated NFL Week 11 odds.

  • New England Patriots -7 at Atlanta Falcons +7
  • Indianapolis Colts +7 at Buffalo Bills -7
  • New Orleans Saints +3 at Philadelphia Eagles -3
  • Miami Dolphins -3.5 at New York Jets +3.5
  • Washington Football Team +3 at Carolina Panthers -3
  • Detroit Lions +13 at Cleveland Browns -13
  • San Francisco 49ers -6.5 at Jacksonville Jaguars +6.5
  • Houston Texans +10 at Tennessee Titans -10
  • Green Bay Packers -1.5 at Minnesota Vikings +1.5
  • Baltimore Ravens -5 at Chicago Bears +5
  • Cincinnati Bengals -1.5 at Las Vegas Raiders +1.5
  • Arizona Cardinals +3 at Seattle Seahawks -3
  • Dallas Cowboys +2.5 at Kansas City Chiefs -2.5
  • Pittsburgh Steelers +6 at LA Chargers -6
  • New York Giants +10.5 at Tampa Bay Buccaneers -10.5

Thursday, Nov. 18

New England Patriots (-6.5) at Atlanta Falcons (+6.5)

The Patriots continued their strong play in Week 10, recording their fourth straight win with a 45-7 thumping of the Cleveland Browns. The Falcons were on the wrong end of a similar throttling, as the Cowboys handed them a 43-3 loss.

New England didn’t have Damien Harris (concussion) available for Sunday’s contest, but that hardly mattered with rookie Rhamondre Stevenson rushing for 100 yards and two scores. Mac Jones added three touchdown tosses of his own and continued to display excellent rapport with his diverse group of pass catchers. The Pats now have a chance to catch what may well be a disheartened Atlanta team on a short week.

The Falcons seemed to be hitting a relatively good note prior to Sunday, as they’d managed to bring their record to 4-4 and were getting by without Calvin Ridley (personal) reasonably well. Any momentum came to an abrupt, grinding halt at AT&T Stadium, however. The defeat was so thorough that it does lend credence to the notion of an outlier, but it may have also exposed how a pedestrian receiving corps can catch up to a team after a few games. If that is indeed the case, a defense coordinated by Bill Belichick is arguably the worst opponent to face in the immediate aftermath.

The public is increasingly believing in New England, as the Pats’ projected advantage moved a full two points to -6 by Monday morning.

Sunday, Nov. 21

Indianapolis Colts at Buffalo Bills ()

The Colts got themselves to 5-5 with a 23-17 win over the Jaguars on Sunday that once again featured some feisty play from Jacksonville. The Bills made up for their shocking loss to Urban Meyer’s squad in Week 9 with a 45-17 thrashing of the division-rival Jets on the road, a game in which they picked off Mike White four times.

Jonathan Taylor logged over 20 carries for the first time this season against Jacksonville and parlayed them into 116 yards and a touchdown, but he could be hard-pressed to come close to replicating the feat against the Bills’ stout defense. Buffalo allows just 83.9 rushing yards per contest, which could funnel more responsibility to Carson Wentz. However, the matchup through the air is equally thorny, with Buffalo conceding an NFL-low 161 passing yards per game at home and picking off an NFL-high 15 passes overall.

The Bills went a long way toward proving their Week 9 stumble was likely a one-game outlier. The Josh Allen-Stefon Diggs connection also enjoyed its most productive day of the season yet, as the star wideout posted an 8-162-1 line, while the defense continued its league-best play. The competition against the Colts is certainly stiffer, but Indy also suffers from a lack of game-breaking pass catchers at the moment.

The public firmly backs the Bills and their original -6.5 figure has grown slightly following Week 10.

Baltimore Ravens () at Chicago Bears

The Ravens fell victim to a slate-opening upset in Week 10, as the Dolphins upended them in South Florida on Thursday night by a 22-10 margin. The Bears were off in Week 10 following a narrow 29-27 Monday night loss to the Steelers in Week 9.

Baltimore looked out of synch on offense for most of the game against Miami, and their defense may have been thrown off by the in-game switch from Jacoby Brissett to Tua Tagovailoa as well. The Ravens have had some extra time to dissect the disappointing loss and will look to add to the 3-6 Bears’ woes with a bounce-back performance. Chicago has been surprisingly vulnerable in the area that Baltimore is best equipped to exploit – the Bears rank in the bottom 10 of the league with 122.8 rushing yards per contest allowed.

Matt Nagy’s club did have some positives to take from the Week 9 OT loss to the Steelers, as the offense looked better than it had in some time. Rookie quarterback Justin Fields nearly pulled off the upset while throwing for a career-high 291 yards and adding another 45 on the ground. However, he’ll certainly be tested against a savvy veteran defense in that of Baltimore, which hasn’t always played up to its usual standards this season but which could also ultimately make life difficult on a first-year signal-caller.

With the Ravens having played Thursday night and the Bears idle, the look-ahead line remains identical as the week begins.

Detroit Lions at Cleveland Browns ()

The Lions came out of the bye week ready to fight again, and they willed themselves to a 16-16 tie with the Steelers, which played without Ben Roethlisberger (COVID-19 protocols). The Browns were embarrassed on the road by the Patriots to the tune of a 45-7 thumping, and they saw Baker Mayfield exit the game with a knee injury to boot.

The passing game is still a weak spot in Detroit, with Jared Goff throwing a season-low 114 yards against Pittsburgh while battling through an oblique injury he suffered early in the contest. The fact Goff connected on a season-low 56.0 percent of his throws as well coming out of the bye week had to be disappointing, but D’Andre Swift helped alleviate the disillusionment with a massive 33-carry, 130-yard effort. The Browns’ defense was uncharacteristically poor versus the Pats, but they are still allowing the fifth-fewest total yards per game (323.9).

X-rays following Sunday’s game didn’t reveal any structural damage to Mayfield’s knee, so he will likely continue to battle through and start this game. Whether he finishes it is anyone’s guess given the multitude of maladies he’s dealing with, but backup Case Keenum would presumably be in a very good spot as well would he have to enter at some point and face a Lions defense giving up the fifth-most total yards per contest (379.8). Nick Chubb should also be ready to return from the reserve/COVID-19 list for this game, which would certainly offer a nice boost.

With Detroit having played tough and Cleveland having gotten throttled as bad as it did, the Browns’ projected advantage remains the same as in the look-ahead line.

Houston Texans at Tennessee Titans ()

The Texans were idle in Week 10 following a messy 17-9 loss to the Dolphins in Week 9 that marked the return to action of Tyrod Taylor from a hamstring injury. The Titans pushed to 8-2 – and 2-0 in two full games without Derrick Henry (foot) – by squeaking by the Saints, 23-21.

With a game under his belt and the bye week for extra healing and practice, Taylor should be ready to hit the ground running in this matchup. The veteran was showing plenty of good signs before getting hurt, albeit over a small sample size of six quarters. With a serviceable group of pass catchers, he could have a chance to make some inroads against a Tennessee defense allowing the sixth-most passing yards per game (267.9).

The Titans haven’t gotten much from D’Onta Foreman and Adrian Peterson yet as the replacements for Henry, and now Julio Jones is on injured reserve for at least two more games. However, in a credit to Mike Vrabel, his staff and Tennessee’s healthy players on both sides of the ball, the Titans just keep winning. Their matchup against the division-rival Texans shapes up as appealing through both the ground and air, as Houston is allowing the third-most total yards per game (385.9).

The line, which sees the Titans as expected heavy home favorites, remains unchanged from the look-ahead figure as the week begins.

Green Bay Packers () at Minnesota Vikings

The Packers welcomed back Aaron Rodgers for a 17-0 win against the Seahawks in Week 9, but it was the defense that took center stage and gave Russell Wilson a rude welcome back from injured reserve. The Vikings moved to 4-5 with a quality road win against the Chargers, one that featured superior performances from Kirk Cousins, Dalvin Cook and Justin Jefferson.

The Packers’ offense wasn’t what might have been expected with Rodgers’ return and a fully healthy receiving corps, but credit also goes to the Seahawks defense for an inspired effort. Green Bay also saw Aaron Jones sustain what has now been diagnosed as a mild MCL knee sprain and that seems like to lead to missed time, but A.J. Dillon stepped in and thrived with 128 scrimmage yards and two touchdowns. With the Vikings allowing 130.6 rushing yards per contest, the tough-running second-year back could be in for a big day.

Cousins threw for 294 yards and two touchdowns against the Chargers after a pair of sub-200-yard efforts, while Cook contributed 94 yards and a score and Jefferson producing a 9-143 line. The Packers defense shapes up as a tough assignment, however; Green Bay ranks No. 3 in total yards per game (309.9), ranking in the top half of the league against both the run and pass.

Despite Jones’ injury and likely Week 11 absence and the Packers’ road status, their initial projected advantage of 2.0 points has grown slightly following Week 10.

Miami Dolphins () at New York Jets

The Dolphins tripped up the visiting Ravens for Miami’s second win over a five-day span on Thursday night in Week 10, notching a 22-10 victory. The Jets were handed an embarrassing 45-17 loss by the Bills, with young quarterback Mike White coming back down to earth with four interceptions.

Tua Tagovailoa offered the Dolphins’ offense a spark after entering the win over the Ravens for Jacoby Brissett (knee), and coach Brian Flores has already announced that he expects Tagovailoa to be under center for this contest after having had some extra time to rest his fractured finger. The Jets’ defense was particularly poor Sunday and is now allowing an NFL-high 417.1 total yards per contest, so this could be a get-right spot for Miami’s offense as a whole.

Who’ll be under center for the Jets in this contest is the big open question heading into game week. Zack Wilson (knee) could be healthy enough to at least serve as the No. 2 quarterback, and Joe Flacco, who entered Sunday’s lopsided loss late, could be the signal-caller he’s backing up. New York’s passing game seemingly has nowhere to go but up after its Week 10 performance, while impressive rookie running back Michael Carter could be set to produce against a Dolphins surrendering 114.4 rushing yards per road game.

Despite Miami’s impressive upset win and the Jets’ latest rout, the initial look-ahead line of Dolphins -2.5 has inched up only slightly thus far.

New Orleans Saints at Philadelphia Eagles ()

The Saints fought hard behind another solid effort from Trevor Siemian but came up just short against the Titans, 23-21. The Eagles impressed plenty on the way to their fourth win, posting a 30-13 victory over the Broncos on the road.

Despite the narrow two-point loss that dropped them to 5-4, the Saints offense impressively continued to gel around Siemian, who racked up 298 yards and two touchdowns. Mark Ingram’s comeback Saints tour had another successful installment as well, as the veteran compiled 108 total yards and a rushing TD. Alvin Kamara missed the contest with a knee injury, and it remains to be seen if he’ll be ready to face an Eagles defense allowing 127.0 rushing yards per home game.

Philly put up a robust point total Sunday, even with Jalen Hurts throwing for just 178 yards. However, the second-year signal-caller threw two touchdown passes and added 53 rushing yards to play an integral role in the victory. It’s worth noting the passing game remains considerably DeVonta Smith-centric, which could come back to bite Philly against a savvy veteran secondary like New Orleans’. That could be even truer if tight end Dallas Goedert is forced to miss Week 11 with the concussion that forced his early exit Sunday.

Philadelphia’s win in a tough road environment made an impression the public – the game went from a Pick ‘Em look-ahead line to the Eagles as slight favorites, although if Kamara is announced as available at the end of the practice week, there could certainly be some movement.

Washington Football Team at Carolina Panthers ()

Washington notched one of the big upsets of the week by toppling the defending champion Buccaneers, 29-19. The Panthers welcomed back Cam Newton by pulling off a big unexpected win of their own, as they handed the short-handed Cardinals a 34-10 defeat in their own backyard.

Washington got stellar play from Taylor Heinicke against Tampa Bay and the performance was particularly timely; reports indicate that Ryan Fitzpatrick will likely miss the rest of the season with the hip injury he suffered in Week 1. It remains to be seen if the Football Team can carry over the momentum after the emotional victory, but motivation shouldn’t be a problem this week, either, considering the contest marks Ron Rivera’s return to Carolina.

The Panthers signed Newton back just in time to face his old head coach, and the veteran signal-caller is likely to start in Week 11 after seeing action on only a handful of plays Sunday. Newton produced two touchdowns during his limited time on the field against Arizona, but Washington will very likely gameplan for him as the starter during the practice week.

Despite each team’s losing record, this game could draw a fair amount of betting interest. As it is, Carolina’s initial projected advantage of 3 points has already been sliced in half as the week begins.

San Francisco 49ers () at Jacksonville Jaguars

The 49ers close out Week 10 against the division-rival Rams on Monday night as Jimmy Garoppolo aims for his third straight 300-yard effort. The Jaguars fought hard once again against a quality team in the Colts on Sunday but came up just short, 23-17.

Jacksonville’s defense turned in a solid performance after having some considerable trouble slowing down Jonathan Taylor early on. However, the offense wasn’t really able to do its part despite the return of James Robinson from a heel injury following a one-game absence. Trevor Lawrence failed to eclipse 200 passing yards for the second straight game, and he completed a season/career-low 45.7 percent of his throws. The 49ers defense heads into its Monday night matchup the 10th-fewest total yards per game (338.1), so the matchup could be another tough one for the rookie signal-caller.

Ahead of San Fran’s Monday night contest, the Niners were nearly a touchdown road favorite.

Cincinnati Bengals () at Las Vegas Raiders

The Bengals were idle in Week 10 after sustaining a 41-16 thumping at the hands of the Browns in Week 9. The Raiders looked lost at home Sunday night while sustaining their second straight loss, as they dropped a 41-14 decision to the Chiefs.

Cincinnati likely spent its bye week trying to pick up the pieces following the aforementioned Week 9 rout. Joe Burrow, Joe Mixon, Ja’Marr Chase and Tee Higgins are all healthy, so Cincy’s powerful offense should be able to reset and try to bounce back versus a Raiders defense that has struggled the last two weeks and is now allowing 372.4 total yards per game at home.

Vegas’ offense, such a strength earlier in the season, mostly came up empty against a Kansas City defense that has been extremely vulnerable most of the season. Derek Carr does continue to put up solid numbers through the air, but the ground attack was a complete non-factor. The matchup against Cincy’s defense is tough on the ground as well, considering Zac Taylor’s squad is allowing an AFC-low 83.2 rushing yards per road game.

After Vegas’ latest loss the public has bet this game toward the Bengals as the week begins.

Dallas Cowboys at Kansas City Chiefs ()

The Cowboys left no doubt as to whether their poor Week 9 showing against the Broncos was an outlier, decimating the Falcons by a 43-3 score. The Chiefs basically did the same to the division-rival Raiders, handing Las Vegas a 41-14 loss at home.

Dallas’ victory over Atlanta was about as dominating as the final score implies, even though the ground attack didn’t really get going (3.1 yards per carry) and Amari Cooper (4-51) was relatively quiet. However, the Cowboys got Michael Gallup back from his calf injury, and although CeeDee Lamb sustained an arm contusion after producing a 6-94-2 line, he’s expected to be ready for his marquee matchup against the Chiefs.

It’s hard to know whether the Chiefs offense is “fixed” for good, but Patrick Mahomes did at least quiet the growing swell of critics with his 406-yard, five-touchdown tally against the Raiders. Darrell Williams also particularly impressed as a receiver (9-101), while Travis Kelce and Tyreek Hill combined for 202 yards and two touchdowns. The Cowboys’ ball-hawking secondary (NFC-high 14 interceptions) will be an intriguing matchup for Mahomes, who’s certainly had his share of trouble with ball security.

With both teams notching impressive Week 10 wins, the initial look-ahead line of the Chiefs as narrow home favorites remains unchanged.

Arizona Cardinals () at Seattle Seahawks

The Cardinals played without Kyler Murray (ankle) and DeAndre Hopkins (hamstring) again in Week 10 and weren’t able to pull off a second straight win without their star battery, as they dropped a 34-10 decision to the Panthers. The Seahawks got Russell Wilson back from his finger injury but couldn’t parlay that into a win, or even points – they fell to the Packers by a 17-0 score.

Whether Murray and Hopkins are able to return for this game will naturally loom large all week. Colt McCoy suffered a pec strain against Carolina and exited the contest early, but he wasn’t quite having the same degree of success that he’d enjoyed against the 49ers in Week 9 anyhow. McCoy would likely be available to start in Week 11 if Murray is unavailable, but if he still doesn’t have Hopkins at his disposal, it could lead to another sluggish outing.

The Seahawks defense’s recent performances lend some credence to the notion they could give a short-handed Cardinals offense trouble. Seattle has given up just 37 points over its last three games and defeated Arizona last season in the second meeting by a 28-21 score with Murray and Hopkins available. Given the shutout loss in Wilson’s return, there’s no question the star quarterback and his talented pass catchers are undoubtedly going to be out to atone.

Despite Week 10 results, the public is on the Cardinals and is clearly banking on a Murray return at minimum, as initial Arizona -1 line has grown considerably since it was first released pre-Week 10.

Pittsburgh Steelers at LA Chargers ()

The Steelers found out Saturday they’d be playing Sunday without Ben Roethlisberger (COVID-19 protocols), and although Mason Rudolph turned in a serviceable performance, they still could only tie the winless Detroit Lions, 16-16. The Chargers dropped their third home game of the season, falling 27-20 to the Vikings.

Roethlisberger has publicly said he’s vaccinated, meaning he should be able to return for this contest. If he’s unable to clear protocol, Rudolph, who threw for 242 yards with a touchdown and an interception versus Detroit, would get another call. Los Angeles’ secondary uncharacteristically struggled against the Vikings, but the Bolts are still allowing just 206.0 passing yards per contest. However, the going could be good for rookie Najee Harris if Pittsburgh can get injured offensive lineman Kevin Dotson and Trai Turner back, as the Chargers are yielding an NFL-high 155.1 rushing yards per contest.

The Steelers struggled mightily against the run in their own right Week 10, allowing D’Andre Swift 130 rushing yards. Pittsburgh is now giving up the ninth-most rushing yards per contest (123.0), which could tee up Austin Ekeler for a fruitful performance as well. The secondary also lost Joe Haden to a foot injury during Sunday’s game and then saw Minkah Fitzpatrick go on the reserve/COVID-19 list Monday. Fitzpatrick is vaccinated as well according to reports, and his presence would be crucial against a Chargers passing attack that’s been inconsistent of late but has plenty of upside.

Given the uncertainty regarding some key players for the Steelers – Ben Roethlisberger and T.J. Watt most notably – the Chargers’ projected advantage has already gone up 1.5 points at some books.

Monday, Nov. 22

New York Giants at Tampa Bay Buccaneers ()

The Giants had Week 10 off after notching their second win in three games, a 23-16 victory over the Raiders in Week 9. The Bucs were upset by Washington, 29-19, a loss in which Tom Brady threw a pair of interceptions.

New York got Saquon Barkley (ankle) back into drills for the first time in more than a month Monday, raising the possibility he may be able to suit up for a matchup against a team he suffered a multi-game ankle injury against two seasons ago. The Giants’ bye week came at a very good time considering the amount of injuries the offense has been ravaged with overall, although it’s worth noting Sterling Shepard started the practice week off Monday as a non-participant with his quadriceps injury.

The Buccaneers’ air attack was once again missing both Antonio Brown (ankle) and Rob Gronkowski (back), and it looked like it against a Washington secondary that had been very targetable. The G-Men are allowing a robust 282.5 passing yards per road game and a 68.6 percent completion rate when traveling as well, so even if both players are still missing in Week 11, this could be a rebound spot for what will likely be an ornery Brady.

Bettors were slightly moved by the Buccaneers’ sluggish Week 10 effort, as the look-ahead line of -12 has been chipped away slightly.

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Juan Carlos Blanco

Juan Carlos Blanco has served as a freelance writer for a wide variety of online publications and websites, with an intensive focus on fantasy sports. Juan has provided analysis and comprehensive coverage of the MLB, NBA, NFL, CFL, AAF and AFL while also reporting on news and developments in the daily fantasy sports and online gaming industries.

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