We’re in store for a much more balanced schedule than usual on Sunday as there will be a near-even amount of 1 p.m. ET and 4 p.m. ET games. As we look at NFL Week 10 odds, a Buccaneers versus Panthers divisional battle headlines the early window.
The late window games feature some intriguing quarterback duels as Justin Herbert and Tua Tagovailoa tangle in South Florida and Josh Allen and Kyler Murray face off in the desert.
NFL Week 10 odds
Here are NFL Week 10 odds from FanDuel Sportsbook.
Thursday, Nov. 12
Indianapolis Colts -1 at Tennessee Titans – 8:20 p.m. ET
The Colts were flat offensively against the visiting Ravens in Week 9, leading to a 24-10 defeat that also saw them lose Jack Doyle to a concussion. The Titans weren’t exactly hitting on all cylinders offensively themselves, but they managed to get past the Bears by a 24-17 score to snap a two-game losing streak.
Indianapolis has now lost to both teams with winning records they’ve faced this season but are currently narrow road underdogs at some sportsbooks for Week 10. The Colts will be challenged to get both T.Y. Hilton (groin), who missed Sunday’s contest, and Doyle back in time on the short week. An absence by both would leave Philip Rivers less than ideally equipped try and exploit a Titans defense that’s allowed the sixth-most passing yards per game (299.4) of any team on its home field. Indy has some solid options such as Michael Pittman and Zach Pascal in the pass-catching corps, but none bring the pure explosiveness of Hilton when he’s fully healthy.
The Titans will have their work cut out for them against an Indy defense that remains ranked No. 3 against both the run (83.6 RYPG) and pass (206.4 PYGP). Ryan Tannehill completed less than 50.0% of his throws for the first time this season against the Bears on Sunday, with the absence of ultra-reliable Adam Humphries (head) potentially playing a part. The sure-handed wideout may be challenged to complete the five-step concussion protocol before Thursday. Derrick Henry also struggled to an average of 3.2 yards per carry against Chicago and the Colts’ run defense is an even stingier unit, although Henry did light them up for 149 rushing yards and a TD when he saw them Week 13 of last season.
Sunday, Nov. 15
Houston Texans at Cleveland Browns – 1 p.m. ET
The Texans were finally able to secure their long-awaited second win of the season Sunday in a 27-25 squeaker against the Jaguars that featured Jacksonville rookie Jake Luton’s first professional start. The Browns were on bye Sunday after having suffered a wind-swept 16-6 loss to the Raiders in Week 8.
Houston lost top running back David Johnson to a concussion early in Sunday’s game. That could leave them with Duke Johnson as their primary backfield option in a favorable matchup versus a Browns defense that’s been much better against the run than the pass. Therefore, it could be a busy day for Deshaun Watson, who connected on long TDs to Will Fuller and Brandin Cooks on Sunday and will have chance to exploit Cleveland’s secondary. It is worth noting, though, that the Browns home/road pass-defense splits are as dramatic as any in the league (207.8 PYPG allowed at home/321.5 PYPG on road).
The Browns figure to have much less resistance. The Texans can’t stop either the run or pass, ranking in the bottom 10 in both passing yards (257.4) and rushing yards (159.5) allowed per game, the latter figure being league-worst. However, Baker Mayfield will enter this matchup sans his top receiver in Odell Beckham (IR-knee). Whether remaining healthy weapons Jarvis Landry, Rashard Higgins and Donovan Peoples-Jones can help make up for his absence remains to be seen. Meanwhile, Nick Chubb (IR-knee) returned to practice Monday and reportedly looked good.
Despite Beckham’s absence and uncertainty regarding Chubb, the Browns are currently ().
Saturday, 11/14 Update: Chubb is now confirmed to be ready for his return Sunday, but a weather outlook that includes potential maximum gusts in excess of 50 mph has brought the total on this game down from 55.0 at the beginning of the week all the way down to 45.5 as of late Saturday night. The Browns have also seen their projected advantage increase to ().
Philadelphia Eagles at New York Giants – 1 p.m. ET
The Eagles were off in Week 9 after having notched their third win of the season in Week 8 over a depleted Cowboys team. The Giants survived against the Washington Football Team in Week 9 after nearly blowing a 23-10 lead in the fourth quarter.
The Eagles needed a furious fourth-quarter comeback and a strip-sack of Daniel Jones when they squeezed out a one-point win against Big Blue in Week 7. However, they also played that contest with multiple missing offensive pieces. The Week 10 rematch could well see Philadelphia’s Miles Sanders (knee) and Alshon Jeffery (calf) available, but DeSean Jackson, who suffered an ankle injury late in the first game, will still be sidelined.
The Giants statistically have a better matchup on the ground than through the air against the Eagles. Unfortunately for New York, it’s had trouble consistently moving the ball through either method. However, recent signee Alfred Morris offered some reason for optimism by gaining 67 yards on nine rushes Sunday. If Devonta Freeman (ankle) is also available for Week 10 after two straight absences, New York could have an effective veteran backfield to attack a Philly defense that’s allowed 130.8 rushing yards per contest with. Under center, Jones will need to curtail the turnovers that have frequently done him in this season – the second-year signal caller has given the ball up 13 times (nine interceptions, four lost fumbles) through nine games.
Even with some injury questions for Philadelphia, the Eagles are currently () road favorites.
Saturday, 11/14 Update: Sanders and Jeffery are now confirmed available for the Eagles, which have seen their projected advantage bump up a point in some sportsbooks as of late Saturday night.
Washington Football Team at Detroit Lions – 1 p.m. ET
The Washington Football Team lost starting quarterback Kyle Allen to a serious ankle injury in its narrow Week 9 loss to the Giants, but veteran and interim starter Alex Smith offered some reason for optimism by exceeding 300 passing yards. The Lions dropped their third home game of the campaign to the division-rival Vikings and lost Matthew Stafford during the contest to a head injury. The veteran did subsequently clear concussion protocol.
While Smith performed admirably in emergency duty Sunday, he also threw three interceptions. One appeared to not be his fault and there was undoubtedly rustiness to contend with for the veteran, who was seeing his first truly extended game action since 2018. Therefore, the turnovers may not necessarily be indicative of future performance. Smith will certainly have a favorable matchup with which to get right – Detroit is allowing 243.9 passing yards per contest, a 64.9 percent completion rate and a 17:5 TD:INT.
Even with Stafford available, the Lions could be challenged to consistently make inroads against a Washington defense that’s quietly been overperforming the team’s overall record. The WFT is allowing an NFL-low 185.6 passing yards per contest. Washington has also recorded the fourth-most sacks (27), while Detroit has given up a league-high 32. Stafford could also well be without top receiver Kenny Golladay (hip) again. The Lions would likely be set up for much more success on the ground, with the WFT yielding 150 rushing yards per road contest.
However, they continue to split the backfield work among the trio of D’Andre Swift, Adrian Peterson and Kerryon Johnson.
Even with the uncertainty surrounding Golladay, the Lions are currently listed as ().
Saturday, 11/14 Update: Golladay is now confirmed out for a second straight game.
Jacksonville Jaguars at Green Bay Packers – 1 p.m. ET
The Jaguars fell yet again Sunday against the Texans, but rookie quarterback Jake Luton’s 304 yards and a touchdown were reason for optimism. The Packers blasted the short-handed 49ers by a 34-17 score to open Week 9 on Thursday night, a game that marked the return to action of Aaron Jones from a calf injury.
Luton certainly earned another start with his Week 9 performance, not that Gardner Minshew (thumb) would be ready to return for this contest anyhow. Luton displayed excellent rapport with D.J. Chark in Week 9, connecting with the speedy wideout on seven occasions for 146 yards and a touchdown. However, the matchup will get appreciably more difficult for the duo Week 10. The Packers have yielded the fourth-fewest passing yards per contest (206.0) of any team on its home field.
The high-powered Packers clearly have a better matchup all the way around. The Jaguars defense, much like that of their division mate Houston, has struggled to slow down teams no matter how they’ve attacked. Jacksonville is allowing a robust 138.1 rushing yards per game, including 148.0 per road contest. Then, Jacksonville is also giving up 309.2 passing yards per road game. Both numbers spell serious trouble with the likes of Jones, Aaron Rodgers and Davante Adams on tap in this matchup.
Green Bay is currently a () favorite, unsurprisingly the week’s biggest spread in the wake of the considerable gulf in talent between the two squads.
Tampa Bay Buccaneers at Carolina Panthers – 1 p.m. ET
The Buccaneers () suffered an utterly embarrassing loss to the Saints in the second 2020 installment of Brady-Brees on Sunday night, dropping a 38-3 decision despite the addition of Antonio Brown to the team’s already-stacked offensive arsenal. The Panthers gave the defending-champion Chiefs all they could handle at Arrowhead before falling 33-31. The contest marked the return of Christian McCaffrey from injured reserve, but the star running back suffered a shoulder injury late in the game and could be in danger of missing this divisional clash.
On the bright side for the Bucs, there’s nowhere to go but up after Sunday night’s disaster. Tampa Bay is naturally exponentially better than it demonstrated. The Panthers could be the victims of some unfortunate timing to catch what will undoubtedly be an ornery Tom Brady and teammates. Brown had a relatively quiet but decent debut with a 3-31 line. He’ll likely be even more involved Week 10, alongside Mike Evans and Chris Godwin. However, the Panthers defense has been increasingly impressive as the season has gone on, their eventual collapse against the elite weapons of the defending SB champs Sunday notwithstanding.
Teddy Bridgewater continued to thrive in Sunday’s loss by throwing for 310 yards and two TDs. He could have plenty on his shoulders against Tampa Bay if McCaffrey is sidelined yet again. Mike Davis has naturally already proven to be a highly capable fill-in if needed. However, whether it’s McCaffrey, Davis or a combination of both, the matchup against the Bucs’ run defense is among the most unenviable in the league. They’re allowing a league-low 77.9 rushing yards per contest and have done an excellent job limiting the damage from McCaffrey the last three times they’ve faced him. The air may represent a path of lesser resistance for Carolina. The Bucs gave up 282 passing yards, 8.1 yards per attempt and four touchdowns to Brees, Taysom Hill and Jameis Winston on Sunday night. Bridgewater notably threw for a season-high 367 yards in the Week 2 loss to the Bucs as well.
Saturday, 11/14 Update: McCaffrey is confirmed out for Sunday’s game, although the favored Bucs are currently listed as (), a number that’s a full point down from the beginning of the week at some sportsbooks.
Los Angeles Chargers at Miami Dolphins – 4:05 p.m. ET
The Chargers stayed on brand in Week 9, much to their chagrin. Los Angeles dropped yet another close decision, falling to the Raiders by a 31-26 score. Meanwhile, the Dolphins’ impressive rise continued with a major boost from Tua Tagovailoa, who looked much better than in his Week 8 debut. The fifth overall pick threw for 248 yards and two touchdowns while adding another 35 yards on the ground in a wild 34-31 win over the Cardinals.
Los Angeles’ Week 9 stumble followed a familiar pattern – the offense thrived but the defense stumbled, especially late. They’ll now be challenged against a Dolphins defense that’s allowing the fifth-fewest points per game (20.1) and that’s surrendered just 11 passing touchdowns on the campaign. Miami’s cornerback tandem of Xavien Howard and Byron Jones have each allowed sub-50-percent completion rates in primary coverage. Herbert does come into the contest armed with some formidable weapons, as Keenan Allen, Mike Williams, Hunter Henry and Tyron Johnson offer plenty of explosiveness. Then, the maligned Dolphins run defense has actually been very good at home with just 114.0 rush yards per contest allowed.
The Dolphins are tangling with a Chargers defense that’s arguably underperformed relative to preseason expectations and which has now given up 29 or more points in five straight games. Tagovailoa’s strides in Week 9 were critical after his sub-100-yard effort in his debut against the Rams. The rookie has turned the ball over just once over his first two starts, and he’ll have a chance to keep that streak going against a Los Angeles secondary that’s managed just four interceptions in eight games. Tua and his receivers may represent Miami’s best path to success, as the Dolphins backfield is hurting and the Bolts have been particularly effective against the run on the road (110.0 RYPG). Miami RB Matt Breida (hamstring) is expected to miss today’s game.
In a sign of the Dolphins’ improving stock, they’re currently () favorites.
Denver Broncos at Las Vegas Raiders – 4:05 p.m. ET
The Broncos fought hard yet again in Week 9 but couldn’t pull out the victory this time around despite an impressive comeback, falling to the Falcons by a 34-27 score. The Raiders were able to conquer the division-rival Chargers on the road, hanging on for a 31-26 victory with a pair of key late defensive plays in the end zone.
Drew Lock continues to make significant strides by the week, and the rapport he demonstrated with rookie receivers Jerry Jeudy and K.J. Hamler on Sunday was particularly noteworthy. The pair, along with downfield threat Tim Patrick, could play a significant role against a Raiders team allowing 318.3 passing yards per home game. Las Vegas has been much tougher versus the run, especially at home, where it’s allowed just 86.7 rushing yards per contest. Considering the Broncos’ offensive line has generated just 3.98 adjusted line yards per carry, it could be another heavy passing day for Lock.
The Raiders got by with a sub-200-yard effort from Derek Carr against Los Angeles. However, the veteran quarterback continues to produce the best numbers of his career. Carr now has a 16:2 TD:INT and is completing an impressive 69.8 percent of his passes. If Denver’s secondary is still down A.J. Bouye (concussion) and Bryce Callahan (ankle) for this contest, the best path to victory for Las Vegas could be through the air – Denver is yielding just 111.8 rushing yards per road game and giving up a respectable 4.28 RB yards per carry.
The Raiders are just 1-2 ATS at home but are currently () favorites.
Buffalo Bills at Arizona Cardinals – 4:05 p.m. ET
The Bills impressively went toe-to-toe with Russell Wilson in Week 9 and emerged victorious, notching a hard-fought 44-34 win over the Seahawks at home. The Cardinals also put up plenty of points and saw their quarterback put together some highly impressive numbers. Nevertheless, they came up just short against the surging Dolphins, 34-31.
Allen’s return to statistical glory Sunday followed a pair of sub-par passing efforts in the prior three games. John Brown appears to be back to full speed for Buffalo after struggling with a knee injury and the Bills’ offensive arsenal sets up well for a shootout against Kyler Murray and his talented teammates. The Cardinals are allowing 256.0 passing yards per game at home and were just lit up by rookie Tua Tagovailoa.
Murray has now thrown for Sunday’s 283 yards or greater in three of the last four games while tossing multiple touchdowns in three straight as well. He’s also coming off his first 100-yard rushing day of the season in Week 9 and has started to show excellent rapport with speedy Christian Kirk. The third-year wideout has five touchdowns over the last three games and is coming off his first 100-yard effort of the season Sunday. The Bills secondary has some notable names, but Buffalo has allowed a 67.8 percent completion rate and also given up four rushing touchdowns and a 5.1 yards per carry average to quarterbacks.
In what could be easily be the highest-scoring game of the week, this interconference clash currently carries a projected total of ().
Cincinnati Bengals at Pittsburgh Steelers – 4:25 p.m. ET
The Bengals enjoyed a Week 9 bye after an inspiring 31-20 win over the Titans in Week 8, one that saw Joe Burrow turn in a mistake-free, two-touchdown effort. The Steelers saw their undefeated mark hang in the balance until the last play of the game for the second consecutive week, and just as in Week 8 against the Ravens, the secondary made a play and Pittsburgh edged the Cowboys by a 24-19 score.
Burrow has demonstrated weekly progress and coach Zac Taylor continues to put significant trust in the rookie to handle an abundance of pass attempts, regardless of opponent. Burrow has 37 or more pass attempts in five of eight games and has eclipsed 300 passing yards in six contests overall, including three straight. While the matchup against the Steelers defense is unfavorable regardless of where one turns, it’s arguably a bit easier through the air (214.6 YPG allowed) than on the ground (102.8 YPG, 3.25 adjusted line yards per carry surrendered). Joe Mixon (foot) could make it back for Cincy in time for this game, however.
The Steelers will try to avoid a repeat of a three-quarter letdown against Dallas that nearly cost them a victory. James Conner suffered through a surprisingly difficult day against the Cowboys’ mediocre run defense, but has an excellent opportunity to get right in this matchup. Cincinnati has struggled to defend the run all season and is allowing 152.5 rushing yards per road game. Ben Roethlisberger suffered knee injuries that knocked him out briefly just before halftime versus the Cowboys; however, he returned and should be in line to suit up in this divisional showdown.
Although the Bengals have made significant strides under Taylor and Burrow, the home-field Steelers are still currently favored by ().
Saturday, 11/14 Update: After a stint on the reserve/COVID-19 list earlier in the week due to close contact with infected teammate Vance McDonald, Roethlisberger is set to play Sunday and also avoided the injury report altogether with respect to his knee issues.
San Francisco 49ers at New Orleans Saints – 4:25 p.m. ET
The 49ers limped into a Week 9 Thursday night battle versus the Packers with a laundry list of absences and it was reflected in their play. San Fran was walloped by Green Bay, 34-17. The Saints had a polar opposite Week 9 experience. Drew Brees and his teammates absolutely steamrolled the Buccaneers on the road by a 38-3 score, a game that marked the return to action of both Michael Thomas and Emmanuel Sanders from a hamstring injury and COVID-list stint, respectively.
San Francisco has a chance to field a much healthier offense in Week 10. While Jimmy Garoppolo (ankle) is expected to remain sidelined, the wideout trio of Deebo Samuel, Brandon Aiyuk and Kendrick Bourne could all be available for this game. So, too, could running back Tevin Coleman (knee). Then, receiver Richie James certainly made a case for additional playing time with a 9-184-1 line against Green Bay and could help round out the aerial weaponry nicely for interim starter Nick Mullens. He’ll need all the help he can get against a New Orleans defense that was suffocating Sunday night against Tom Brady and that’s been especially tough versus the run.
With Thomas and Sanders back in the fold, Brees now has a four-deep receiver corps consisting of the two of them, Tre’Quan Smith and impressive undrafted rookie Marquez Calloway. Paired with elite pass-catching back Alvin Kamara and savvy veteran tight Jared Cook, the Saints passing game could be ramping up at just the right time of the season. The matchup against San Francisco’s defense is still tough, but the Niners are missing several key starters from last year’s outstanding unit due to injury.
The difference in the caliber of starting quarterbacks and the ongoing absence of George Kittle (foot) help to currently make the Saints robust favorites by ().
Saturday, 11/14 Update: Aiyuk and Bourne will be back for San Francisco, while Coleman and Samuel will remain out. The line essentially remains unchanged, however, with New Orleans still a heavy favorite.
Seattle Seahawks at Los Angeles Rams – 4:25 p.m. ET
The Seahawks () battled hard on the road against the Bills in Week 9, but even with the return of Jamal Adams from a groin injury, Seattle’s porous secondary still allowed 415 yards and three touchdowns to Josh Allen in a 44-34 loss. The Rams were on bye in Week 9, licking their wounds after dropping a rather surprising 28-17 decision to the Dolphins on the road in Week 8.
Wilson, always careful with the ball, has thrown five of his eight interceptions on the season in Weeks 7 and 9. Whether that’s just a blip remains to be seen; however, he’ll have to tread carefully against a Rams secondary that’s given up the second-fewest passing yards per game (197.1), picked off six passes and yielded a modest 22.3 completions per game. Los Angeles also held Wilson to 245 yards, no touchdowns and one interception when last seeing him Week 14 of last season and have a shutdown corner in Jalen Ramsey that could help mitigate some of the damage from D.K. Metcalf and Tyler Lockett.
Seattle’s problems in the secondary are threatening to derail its path to the ultimate goal of a Super Bowl victory. While Los Angeles doesn’t run anywhere near as aggressive a passing attack as Buffalo’s, coach Sean McVay is certainly adaptable enough to lean a little heavier on it and has the weapons to make it work when the matchup calls for it. The discrepancy between the Seahawks’ No. 32 ranking against the pass (362.1 YPG allowed) and their No. 4 mark against the run (93.6 YPG surrendered) jumps off the page. The Rams should have Darrell Henderson recovered from the thigh injury he suffered against the Dolphins in Week 8. He remains the team’s most effective runner if they choose to try and test Seattle’s stingy front.
Saturday, 11/14 Update: Chris Carson and Carlos Hyde will remain out with foot and hamstring injuries, respectively, for Seattle. The confirmed absences may have played a part in this line moving from Rams -1 to its current line of Rams ()
Baltimore Ravens at New England Patriots – 8:20 p.m. ET
The Ravens finally got a win over a quality team with a 24-10 victory over the Colts in Week 9. The Patriots had to sweat it out, but they toppled the winless Jets by a 30-27 score with a late interception and two clutch scoring drives Monday night.
The Ravens continued to get by without Mark Ingram (ankle), but J.K. Dobbins and Gus Edwards are doing an adequate job keeping the non-Lamar Jackson portion of the running game afloat. The good news for Jackson and the improvement he needs to continue demonstrating is that New England’s defense continued to struggle mightily against what had been a moribund offense in the Jets. The Pats are especially vulnerable on the ground (140.4 YPG allowed), which is the worst possible weakness to have when facing Baltimore.
The Patriots saw Cam Newton have one of his best games yet in the narrow Week 9 win, locking in his job for at least another week. Perhaps the most encouraging aspect of a closer-than-expected win for the Pats was the play of second-year wideout Jakobi Meyers, who exploded for a career-best 12-169 line against New York. Baltimore’s defense has had some difficulties defending the deep pass at times this season and has only four interceptions. Nevertheless, the Ravens are giving up a modest 223.1 passing yards per game overall and have also racked up 24 sacks. The Patriots have been one of the best at protecting the QB, however, as they’ve allowed just nine sacks over eight games.
New England’s comeback win Monday night notwithstanding, the Ravens are currently comfortable () favorites.
Monday, Nov. 16
Minnesota Vikings at Chicago Bears – 8:15 p.m. ET
The Vikings had a completely forgettable start to the season, but they took another step toward clawing out of their hole with their second straight victory. Minnesota scored a 34-20 win over the Lions in a game where Dalvin Cook continued advancing his MVP candidacy with 252 total yards and two rushing TDs. The Bears offense continued sputtering against a Titans defense that had been beatable, losing 24-17 on the road in a game that wasn’t as close as the final score indicated.
Cook is clearly the driving force of Minnesota’s offense, but he’ll have a much tougher matchup in what will be the Vikes’ third consecutive divisional game. The Bears have allowed just 101.5 rushing yards per game at home. Kirk Cousins has only had to put up a total of 34 attempts over the last two games. If he does have to turn more often to the air, Adam Thielen and Justin Jefferson are fine options. Yet, Chicago’s defense is also ranked in the top 10 with 218.2 passing yards per game and a 60.1 percent completion rate allowed.
The Bears are struggling to put four quarters of offense together, and it’s costing them against quality teams. Chicago is averaging the fifth-fewest first-half points per game (8.8). That includes a total of three points against the Rams in Week 7 and none versus the Titans in Week 9. Nick Foles is racking up aesthetically pleasing numbers, but the only issue is they’re often coming in garbage time of late. David Montgomery is not only averaging just 3.6 yards per carry and is now dealing with a concussion.
Both teams rank in the top 10 in red-zone touchdown success rate allowed – in fact, the Bears are generating an NFL-best 41.9 percent in that category – and the contest unsurprisingly currently carries a projected total of ().
Saturday, 11/14 Update: Allen Robinson appears to be shaping up as a true game-time decision for the Bears due to a knee injury, while Montgomery has now been ruled out with his concussion. Meanwhile, the line has moved from an open of Bears -1 to a current one of Vikings (), some of the biggest movement of the week as far as point spreads.
Lookahead line vs. current line
Taking stock of each game’s opening line versus the current spread.
|Game||Lookahead line||Current spread|
|Indianapolis at Tennessee||TEN -1||IND -1|
|Cincinnati at Pittsburgh||PIT -10.5||PIT -6.5|
|Houston at Cleveland||CLE -2.5||CLE -4.5|
|Jacksonville at Green Bay||GB -13.5||GB -14|
|Philadelphia at NY Giants||PHI -3||PHI -4.5|
|Tampa Bay at Carolina||TB -6.5||TB -5.5|
|Washington at Detroit||DET -4||DET -3|
|Buffalo at Arizona||ARI -2.5||ARI -2.5|
|Denver at Las Vegas||LV -4||LV -3.5|
|LA Chargers at Miami||MIA -1.5||MIA -1.5|
|San Francisco at New Orleans||NO -10||NO -9.5|
|Seattle at LA Rams||LAR -1||LAR -2.5|
|Baltimore at New England||BAL -6.5||BAL -6.5|
|Minnesota at Chicago||CHI -1.5||MIN -3.5|