NFL Divisional Opening Odds: Dallas Cowboys at San Francisco 49ers

Written By Brett Gibbons on January 16, 2023
Cowboys 49ers odds

The San Francisco 49ers (14-4) host the Dallas Cowboys (13-5) in the NFC Divisional Round Round at Levi’s Stadium on Sunday, Jan. 22 at 6:30 p.m. ET/3:30 p.m. PT. The last time these two historic teams squared off was in last year’s Wild Card round, where the 49ers advanced en route to an NFC Championship appearance. The 49ers opened as -4.5 favorites at FanDuel Sportsbook and the Cowboys opened at +180 on the money line. Find Cowboys at 49ers NFC Divisional opening odds below.

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NFL Divisional Opening Odds: Cowboys At 49ers

Place a bet on NFC Divisional Round opening odds by clicking on the odds in the table below. Toggle between point spread, money line, and point total in the listed tabs.

Point Spread
Money Line

Game
(Eastern Time)
(EST)
Cowboys
Bet now
+4.5
49ers
Bet now
-4.5

Game
(Eastern Time)
(EST)
Cowboys
Bet now
+180
49ers
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-215

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How The 49ers Got Here

Riding an 11-game win streak, the 49ers are the NFL’s hottest team. Despite losing their top two quarterbacks, Brock Purdy rose to the occasion, going 6-0 and passing for at least two touchdowns in every start so far. Purdy peaked in the second half of the NFC Wild Card round, becoming the first rookie to combine for four touchdowns in a playoff game.

Of course, the Kyle Shanahan system enables a mistake-free QB like Purdy to thrive. In the five regular season games, Purdy still posted a -0.9% CPOE (completion percentage over expected). Having super weapons like Deebo Samuel, Christian McCaffrey, and George Kittle certainly help, but Purdy is playing relatively mistake-free football.

The offense is humming, but the 49ers defense is the moneymaker. First team All-Pros Nick Bosa and Fred Warner create consistent matchup problems for opposing offenses. San Francisco overtook the number-one seed Philadelphia Eagles as the Super Bowl 57 favorite out of the NFC.

How The Cowboys Got Here

The Dallas defense harassed a listless Buccaneers offense all game long in the NFC Wild Card round on Monday night. Dak Prescott turned in an efficient performance, facing little resistance. Now, he’s thrown headlong into a road match with the NFL’s hottest team and top scoring defense.

Micah Parsons leads a disruptive Cowboys front that finished third in pressure rate in the regular season. Derivative from the pressure comes a league-leading 17 fumble recoveries. An added 16 interceptions resulted in the Cowboys finishing second in turnover differential at +10.

However, tackle Jason Peters exited the Wild Card win over the Buccaneers with an injury. Rookie Tyler Smith would fill in for Peters should he not be able to go in the Divisional Round. With opposition like Bosa, the Cowboys need all of the offensive line health and prowess they can get.

The Cowboys still sit behind the 49ers and Eagles in Super Bowl 57 odds.

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Brett Gibbons Avatar
Written by
Brett Gibbons

Brett is an avid sports traveler and former Division-I football recruiter for Bowling Green and Texas State. He’s a graduate of BGSU and works as an auditor for Google content curation products. He’s also contributed to Sports Illustrated and Fansided during his young writing career.

View all posts by Brett Gibbons