The NFL’s always busy offseason enjoyed a big night on May 11 with the league rolling out its entire 18 week regular season schedule for 2023. NFL lines for every game are available to bet on now. In a landscape that includes an ever-expanding sports betting space, that also means it’s never too early to take a first glance at what appear to be the most attractive matchups on each weekly slate, as well as select opening lines for what could be some of the most consequential contests of the season.
Week 1
The NFL wastes no time capturing the football fan’s imagination to open the season, as the defending champion Chiefs will host the intriguing Lions on Thursday night in the league’s annual Kickoff Game. Detroit is a trendy preseason NFL betting pick to continue the surge it began during its 9-8 campaign in 2022, and its presence in this nationally televised showcase is nearly inconceivable when considering the years of futility the franchise and its fans endured until recently.
The rest of the Week 1 schedule will be loaded with plenty of highly anticipated matchups as usual — a Texans-Ravens clash expected to feature a C.J. Stroud-Lamar Jackson quarterback duel; Bryce Young’s projected pro debut against the Falcons; the start of the Jordan Love Era in a Packers-Bears NFC North battle; Derek Carr’s Saints debut and Jimmy Garoppolo’s first game in Carr’s old Raiders starting quarterback spot; and a Bills-Jets Monday night battle on Sept. 11 that will see Aaron Rodgers don a non-Green Bay uniform for the first time.
Go here for a full breakdown of NFL Week 1 odds for the 2023 season.
| Date | Start Time | Opening NFL Week 1 odds |
| Thursday, September 7 | 8:20 p.m. ET | Detroit Lions +6.5 at Kansas City Chiefs -6.5 |
| Sunday, September 10 | 1 p.m. ET | Cincinnati Bengals -2.5 at Cleveland Browns +2.5 |
| Sunday, September 10 | 1 p.m. ET | Houston Texans +9 at Baltimore Ravens -9 |
| Sunday, September 10 | 1 p.m. ET | Tampa Bay Buccaneers +7 at Minnesota Vikings -7 |
| Sunday, September 10 | 1 p.m. ET | Tennessee Titans +3.5 at New Orleans Saints -3.5 |
| Sunday, September 10 | 1 p.m. ET | San Francisco 49ers -3 at Pittsburgh Steelers +3 |
| Sunday, September 10 | 1 p.m. ET | Carolina Panthers +2.5 at Atlanta Falcons -2.5 |
| Sunday, September 10 | 1 p.m. ET | Arizona Cardinals +5.5 at Washington Commanders -5.5 |
| Sunday, September 10 | 1 p.m. ET | Jacksonville Jaguars -3.5 at Indianapolis Colts +3.5 |
| Sunday, September 10 | 4:25 p.m. ET | Philadelphia Eagles -4.5 at New England Patriots +4.5 |
| Sunday, September 10 | 4:25 p.m. ET | Green Bay Packers +2.5 at Chicago Bears -2.5 |
| Sunday, September 10 | 4:25 p.m. ET | LA Rams +5.5 at Seattle Seahawks -5.5 |
| Sunday, September 10 | 4:25 p.m. ET | Las Vegas Raiders +3.5 at Denver Broncos -3.5 |
| Sunday, September 10 | 4:25 p.m. ET | Miami Dolphins +2.5 at LA Chargers -2.5 |
| Sunday, September 10 | 8:20 p.m. ET | Dallas Cowboys -2.5 at New York Giants +2.5 |
| Monday, September 11 | 8:15 p.m. ET | Buffalo Bills -2.5 at New York Jets +2.5 |
Week 2
The Week 2 slate begins with a Vikings-Eagles TNF showdown in Philadelphia that could certainly prove to be a postseason preview, given the talent on both squads. A Raiders cross-country visit to Buffalo will give Garoppolo a tough early test on his new squad in an environment he knows well from his AFC East days. The first Ravens-Bengals divisional showdown of the season and an early litmus test against the defending champion Chiefs for a Jaguars team expected to take another step forward this season are some of the marquee games on the early Sunday slate, while a Rodgers-Dak Prescott face-off in Big D, the first Dolphins-Patriots matchup of the season on Sunday night and a division-rivalry MNF doubleheader consisting of Saints-Panthers and Browns-Steelers battles close out the ledger.
| Date | Start Time | Opening NFL Week 2 Odds |
| Thursday, September 14 | 8:15 p.m. ET | Minnesota Vikings +5.5 at Philadelphia Eagles -5.5 |
| Sunday, September 17 | 1 p.m. ET | Las Vegas Raiders +7.5 at Buffalo Bills -7.5 |
| Sunday, September 17 | 1 p.m. ET | LA Chargers -3.5 at Tennessee Titans +3.5 |
| Sunday, September 17 | 1 p.m. ET | Baltimore Ravens +3.5 at Cincinnati Bengals -3.5 |
| Sunday, September 17 | 1 p.m. ET | Seattle Seahawks +2 at Detroit Lions -2 |
| Sunday, September 17 | 1 p.m. ET | Indianapolis Colts +1 at Houston Texans -1 |
| Sunday, September 17 | 1 p.m. ET | Green Bay Packers -1 at Atlanta Falcons +1 |
| Sunday, September 17 | 1 p.m. ET | Chicago Bears -1.5 at Tampa Bay Buccaneers +1.5 |
| Sunday, September 17 | 1 p.m. ET | Kansas City Chiefs -3 at Jacksonville Jaguars +3 |
| Sunday, September 17 | 4:05 p.m. ET | San Francisco 49ers -3 at LA Rams +3 |
| Sunday, September 17 | 4:05 p.m. ET | New York Giants -4 at Arizona Cardinals +4 |
| Sunday, September 17 | 4:25 p.m. ET | New York Jets +1 at Dallas Cowboys -1 |
| Sunday, September 17 | 4:25 p.m. ET | Washington Commanders +3.5 at Denver Broncos -3.5 |
| Sunday, September 17 | 8:20 p.m. ET | Miami Dolphins -1 at New England Patriots +1 |
| Monday, September 18 | 7:15 p.m. ET | New Orleans Saints +1 at Carolina Panthers -1 |
| Monday, September 18 | 8:15 p.m. ET | Cleveland Browns +1 at Pittsburgh Steelers -1 |
Week 3
The Giants will be a heavily scrutinized team as they try to build on the highly encouraging start to the Brian Daboll Era in 2022, and New York’s thorny early schedule continues in a Thursday night matchup to kick off Week 3 against the 49ers at Levi Stadium. Notable early Sunday battles include a Saints-Packers meeting at Lambeau, a Russell Wilson-Tua Tagovailoa meet-up in South Florida, and Rodgers getting his first taste of the Patriots-Jets rivalry. The late window will see Justin Fields and Patrick Mahomes go head to head for the first time when the Bears visit the Chiefs, and a second consecutive MNF doubleheader includes a Bengals-Rams Super Bowl LVI rematch in Cincinnati.
| Date | Start Time | Opening NFL Week 3 Odds |
| Thursday, September 21 | 8:15 p.m. ET | New York Giants +4.5 at San Francisco 49ers -4.5 |
| Sunday, September 24 | 1 p.m. ET | Houston Texans +7 at Jacksonville Jaguars -7 |
| Sunday, September 24 | 1 p.m. ET | Indianapolis Colts +7 at Baltimore Ravens -7 |
| Sunday, September 24 | 1 p.m. ET | Atlanta Falcons +5 at Detroit Lions -5 |
| Sunday, September 24 | 1 p.m. ET | New Orleans Saints +1 at Green Bay Packers -1 |
| Sunday, September 24 | 1 p.m. ET | Tennessee Titans +4.5 at Cleveland Browns -4.5 |
| Sunday, September 24 | 1 p.m. ET | Denver Broncos +3.5 at Miami Dolphins -3.5 |
| Sunday, September 24 | 1 p.m. ET | LA Chargers -1.5 at Minnesota Vikings +1.5 |
| Sunday, September 24 | 1 p.m. ET | New England Patriots +3.5 at New York Jets -3.5 |
| Sunday, September 24 | 1 p.m. ET | Buffalo Bills -4.5 at Washington Commanders +4.5 |
| Sunday, September 24 | 4:05 p.m. ET | Carolina Panthers +4 at Seattle Seahawks -4 |
| Sunday, September 24 | 4:25 p.m. ET | Chicago Bears +9.5 at Kansas City Chiefs -9.5 |
| Sunday, September 24 | 4:25 p.m. ET | Dallas Cowboys -6.5 at Arizona Cardinals +6.5 |
| Sunday, September 24 | 8:20 p.m. ET | Pittsburgh Steelers +1.5 at Las Vegas Raiders -1.5 |
| Monday, September 25 | 7:15 p.m. ET | Philadelphia Eagles -6 at Tampa Bay Buccaneers +6 |
| Monday, September 25 | 8:15 p.m. ET | LA Rams +7 at Cincinnati Bengals -7 |
Week 4
After a Lions-Packers NFC North battle kicks off the Week 4 slate on Thursday night, we’re treated to the debut of the 2023 International Series with a Falcons-Jaguars matchup in London’s Wembley Stadium. Later in the day, there’s the unfolding of the first Bills-Dolphins matchup of the season, following an intriguing three-game series last year that concluded with Miami giving Buffalo a scare in the AFC Wild Card Game with rookie quarterback Skylar Thompson. A Lamar Jackson-Deshaun Watson showdown in Cleveland is also an eye-catching game in the early window, and a Patriots-Cowboys clash in Dallas highlights the late portion of the schedule. However, the crown jewel of the slate could well be the SNF battle between the Chiefs and the Jets at MetLife Stadium, one KC opens a slim 1-point road favorite for.
| Date | Start Time | Opening NFL Week 4 Odds |
| Thursday, September 28 | 8:15 p.m. ET | Detroit Lions -1.5 at Green Bay Packers +1.5 |
| Sunday, October 1 | 9:30 a.m. ET | Atlanta Falcons +4 at Jacksonville Jaguars -4 (London) |
| Sunday, October 1 | 1 p.m. ET | Denver Broncos -1.5 at Chicago Bears +1.5 |
| Sunday, October 1 | 1 p.m. ET | Minnesota Vikings -1.5 at Carolina Panthers +1.5 |
| Sunday, October 1 | 1 p.m. ET | Tampa Bay Buccaneers +3.5 at New Orleans Saints -3.5 |
| Sunday, October 1 | 1 p.m. ET | Baltimore Ravens +1 at Cleveland Browns -1 |
| Sunday, October 1 | 1 p.m. ET | LA Rams -1 at Indianapolis Colts +1 |
| Sunday, October 1 | 1 p.m. ET | Cincinnati Bengals -4.5 at Tennessee Titans +4.5 |
| Sunday, October 1 | 1 p.m. ET | Miami Dolphins +3.5 at Buffalo Bills -3.5 |
| Sunday, October 1 | 1 p.m. ET | Pittsburgh Steelers -3.5 at Houston Texans +3.5 |
| Sunday, October 1 | 4:25 p.m. ET | Arizona Cardinals +9.5 at San Francisco 49ers -9.5 |
| Sunday, October 1 | 4:25 p.m. ET | Las Vegas Raiders +4.5 at LA Chargers -4.5 |
| Sunday, October 1 | 4:25 p.m. ET | New England Patriots +3.5 at Dallas Cowboys -3.5 |
| Sunday, October 1 | 8:20 p.m. ET | Kansas City Chiefs -1 at New York Jets +1 |
| Monday, October 2 | 8:15 p.m. ET | Seattle Seahawks +1 at New York Giants -1 |
Week 5
The Jaguars are set for a second straight London game to kick off this slate, with the scene shifting to Tottenham Hotspur Stadium for a showdown against the Bills. Bryce Young’s and the new-look Panthers’ visit to the Lions at Ford Field and a pair of intriguing interconference Giants-Dolphins and Saints-Patriots clashes populate the early window, and big-name quarterback matchups are a theme in a late window that includes Bengals-Cardinals, Jets-Broncos and Chiefs-Vikings tilts. Another installment of the classic Cowboys-49ers rivalry on Sunday night – which is also a rematch of postseason matchups between the teams the last two Januaries – is a fitting way to close out what should be an action-packed day.
| Date | Start Time | Opening NFL Week 5 Odds |
| Thursday, October 5 | 8:15 p.m. ET | Chicago Bears +1.5 at Washington Commanders -1.5 |
| Sunday, October 8 | 9:30 a.m. ET | Jacksonville Jaguars +3.5 at Buffalo Bills -3.5 (London) |
| Sunday, October 8 | 1 p.m. ET | New York Giants +4.5 at Miami Dolphins -4.5 |
| Sunday, October 8 | 1 p.m. ET | Tennessee Titans +1 at Indianapolis Colts -1 |
| Sunday, October 8 | 1 p.m. ET | Houston Texans +3 at Atlanta Falcons -3 |
| Sunday, October 8 | 1 p.m. ET | Carolina Panthers +5 at Detroit Lions -5 |
| Sunday, October 8 | 1 p.m. ET | New Orleans Saints +3 at New England Patriots -3 |
| Sunday, October 8 | 1 p.m. ET | Baltimore Ravens -1 at Pittsburgh Steelers +1 |
| Sunday, October 8 | 4:05 p.m. ET | Cincinnati Bengals -7.5 at Arizona Cardinals +7.5 |
| Sunday, October 8 | 4:05 p.m. ET | Philadelphia Eagles -4.5 at LA Rams +4.5 |
| Sunday, October 8 | 4:25 p.m. ET | Kansas City Chiefs -4 at Minnesota Vikings +4 |
| Sunday, October 8 | 4:25 p.m. ET | New York Jets -1 at Denver Broncos +1 |
| Sunday, October 8 | 8:20 p.m. ET | Dallas Cowboys +2 at San Francisco 49ers -2 |
| Monday, October 9 | 8:15 p.m. ET | Green Bay Packers +1.5 at Las Vegas Raiders -1.5 |
Week 6
After Wilson and Mahomes start things off in an AFC West clash at Arrowhead on Thursday night, Vikings-Bears and 49ers-Browns matchups highlight the early-afternoon window of the slate Sunday following a Ravens-Titans morning affair in London. In the late window, Garoppolo faces off against his old Patriots squad, while Rodgers tangles with an old NFC nemesis when the Jets host the Eagles. Giants-Bills and Cowboys-Chargers primetime battles make for a marquee way to close out the ledger.
| Date | Start Time | Opening NFL Week 6 Odds |
| Thursday, October 12 | 8:15 p.m. ET | Denver Broncos +7 at Kansas City -7 |
| Sunday, October 15 | 9:30 a.m. ET | Baltimore Ravens -5.5 at Tennessee Titans +5.5 (London) |
| Sunday, October 15 | 1 p.m. ET | Indianapolis Colts +6.5 at Jacksonville Jaguars -6.5 |
| Sunday, October 15 | 1 p.m. ET | Carolina Panthers +7 at Miami Dolphins -7 |
| Sunday, October 15 | 1 p.m. ET | Washington Commanders +1 at Atlanta Falcons -1 |
| Sunday, October 15 | 1 p.m. ET | Seattle Seahawks +4.5 at Cincinnati Bengals -4.5 |
| Sunday, October 15 | 1 p.m. ET | San Francisco 49ers -1 at Cleveland Browns +1 |
| Sunday, October 15 | 1 p.m. ET | Minnesota Vikings -1 at Chicago Bears +1 |
| Sunday, October 15 | 1 p.m. ET | New Orleans Saints -2.5 at Houston Texans +2.5 |
| Sunday, October 15 | 1 p.m. ET | Detroit Lions -3.5 at Tampa Bay Buccaneers +3.5 |
| Sunday, October 15 | 4:05 p.m. ET | New England Patriots -1.5 at Las Vegas Raiders +1.5 |
| Sunday, October 15 | 4:25 p.m. ET | Arizona Cardinals +4 at LA Rams -4 |
| Sunday, October 15 | 4:25 p.m. ET | Philadelphia Eagles +1 at New York Jets -1 |
| Sunday, October 15 | 8:20 p.m. ET | New York Giants +7 at Buffalo Bills -7 |
| Monday, October 16 | 8:15 p.m. ET | Dallas Cowboys +1 at LA Chargers -1 |
Week 7
A Jaguars-Saints interconference clash on Thursday night is followed by Lions-Ravens, Raiders-Bears and Bills-Patriots battles in the early window Sunday afternoon. The late portion of the schedule is highlighted by a Justin Herbert-Mahomes showdown at Arrowhead, while the Dolphins and Eagles and 49ers and Vikings will close out the schedule in primetime battles that should serve as good mid-season measuring sticks for each team.
| Date | Start Time | Opening NFL Week 7 Odds |
| Thursday, October 19 | 8:15 p.m. ET | Jacksonville Jaguars -1 at New Orleans Saints +1 |
| Sunday, October 22 | 1 p.m. ET | Buffalo Bills -2.5 at New England Patriots +2.5 |
| Sunday, October 22 | 1 p.m. ET | Detroit Lions +2 at Baltimore Ravens -2 |
| Sunday, October 22 | 1 p.m. ET | Atlanta Falcons -1 at Tampa Bay Buccaneers +1 |
| Sunday, October 22 | 1 p.m. ET | Cleveland Browns -3 at Indianapolis Colts +3 |
| Sunday, October 22 | 1 p.m. ET | Las Vegas Raiders +1 at Chicago Bears -1 |
| Sunday, October 22 | 1 p.m. ET | Washington Commanders +2.5 at New York Giants -2.5 |
| Sunday, October 22 | 4:05 p.m. ET | Arizona Cardinals +7 at Seattle Seahawks -7 |
| Sunday, October 22 | 4:05 p.m. ET | Pittsburgh Steelers -1 at LA Rams +1 |
| Sunday, October 22 | 4:25 p.m. ET | Green Bay Packers +3.5 at Denver Broncos -3.5 |
| Sunday, October 22 | 4:25 p.m. ET | LA Chargers +5.5 at Kansas City Chiefs -5.5 |
| Sunday, October 22 | 8:20 p.m. ET | Miami Dolphins +2.5 at Philadelphia Eagles -2.5 |
| Monday, October 23 | 8:15 p.m. ET | San Francisco 49ers -1 at Minnesota Vikings +1 |
Week 8
The first two quarterbacks taken in this April’s draft – Bryce Young and C.J. Stroud – go head to head in Carolina in one of the early window’s most interesting games. A trio of divisional clashes in Vikings-Packers, Patriots-Dolphins and Eagles-Commanders also populate the first part of the ledger, while a Lamar-Kyler Murray battle in the Arizona desert and a Bengals-49ers interconference tilt out west are main events of the late portion of the day. The primetime matchups keep the AFC-NFC theme, as the Bears tangle with the Chargers on Sunday night and the Raiders visit the Lions to cap the slate off 24 hours later.
| Date | Start Time | Opening NFL Week 8 Odds |
| Thursday, October 26 | 8:15 p.m. ET | Tampa Bay Buccaneers +10 at Buffalo Bills -10 |
| Sunday, October 29 | 1 p.m. ET | New England Patriots +4 at Miami Dolphins -4 |
| Sunday, October 29 | 1 p.m. ET | Philadelphia Eagles -4 at Washington Commanders +4 |
| Sunday, October 29 | 1 p.m. ET | Minnesota Vikings -1 at Green Bay Packers +1 |
| Sunday, October 29 | 1 p.m. ET | New Orleans Saints -1.5 at Indianapolis Colts +1.5 |
| Sunday, October 29 | 1 p.m. ET | Jacksonville Jaguars +1 at Pittsburgh Steelers -1 |
| Sunday, October 29 | 1 p.m. ET | Atlanta Falcons +1 at Tennessee Titans -1 |
| Sunday, October 29 | 1 p.m. ET | LA Rams +6 at Dallas Cowboys -6 |
| Sunday, October 29 | 1 p.m. ET | Houston Texans +3 at Carolina Panthers -3 |
| Sunday, October 29 | 1 p.m. ET | New York Jets -1.5 at New York Giants +1.5 |
| Sunday, October 29 | 4:05 p.m. ET | Cleveland Browns +1.5 at Seattle Seahawks -1.5 |
| Sunday, October 29 | 4:25 p.m. ET | Cincinnati Bengals +1 at San Francisco 49ers -1 |
| Sunday, October 29 | 4:25 p.m. ET | Baltimore Ravens -5.5 at Arizona Cardinals +5.5 |
| Sunday, October 29 | 4:25 p.m. ET | Kansas City Chiefs -3.5 at Denver Broncos +3.5 |
| Sunday, October 29 | 8:20 p.m. ET | Chicago Bears +5.5 at LA Chargers -5.5 |
| Monday, October 30 | 8:15 p.m. ET | Las Vegas Raiders +3.5 at Detroit Lions -3.5 |
Week 9
The highly anticipated Tyreek Hill-Chiefs reunion will take place overseas and kick off the Week 9 Sunday schedule as the Dolphins and Kansas City do battle in Germany. In the early portion of the day, Murray and Watson tangle when the Cardinals drop in on the Browns, and the Bears visit the Saints in a battle of what could ultimately be two NFC wild-card qualifiers. The later portion of the day includes a Cowboys-Eagles showdown and a marquee Bills-Bengals Sunday night rematch of January’s AFC divisional-round clash between the two teams. There’s no letdown Monday night, either, as Herbert and Rodgers do battle in the Big Apple in what should be a challenging cross-country test for the Bolts.
| Date | Start Time | Opening NFL Week 9 Odds |
| Thursday, November 2 | 8:15 p.m. ET | Tennessee Titans +4 at Pittsburgh Steelers -4 |
| Sunday, November 5 | 9:30 a.m. ET | Miami Dolphins +5.5 at Kansas City Chiefs -5.5 (Frankfurt, Germany) |
| Sunday, November 5 | 1 p.m. ET | Chicago Bears +2 at New Orleans Saints -2 |
| Sunday, November 5 | 1 p.m. ET | Buccaneers +1 at Texans -1 |
| Sunday, November 5 | 1 p.m. ET | Minnesota Vikings -1 at Atlanta Falcons +1 |
| Sunday, November 5 | 1 p.m. ET | Washington Commanders +3.5 at New England Patriots -3.5 |
| Sunday, November 5 | 1 p.m. ET | LA Rams +1.5 at Green Bay Packers -1.5 |
| Sunday, November 5 | 1 p.m. ET | Arizona Cardinals +7 at Cleveland Browns -7 |
| Sunday, November 5 | 1 p.m. ET | Seattle Seahawks +2.5 at Baltimore Ravens -2.5 |
| Sunday, November 5 | 4:05 p.m. ET | Indianapolis Colts +2.5 at Carolina Panthers -2.5 |
| Sunday, November 5 | 4:25 p.m. ET | Dallas Cowboys +3 at Philadelphia Eagles -3 |
| Sunday, November 5 | 4:25 p.m. ET | New York Giants +1.5 at Las Vegas Raiders -1.5 |
| Sunday, November 5 | 8:20 p.m. ET | Buffalo Bills +1 at Cincinnati Bengals -1 |
| Monday, November 6 | 8:15 p.m. ET | LA Chargers +2 at New York Jets -2 |
Week 10
Young and Fields face off for the first time on Thursday night to kick off the Week 10 slate as the Panthers pay a visit to Soldier Field. Then, after a Colts-Patriots morning battle in Frankfurt, Germany, 49ers-Jaguars and Saints-Vikings are among the most noteworthy games of the early afternoon portion of the Sunday schedule. In the late afternoon, another formidable interconference test awaits the Lions in a visit to the Chargers, while the Giants and Cowboys do battle in Texas as New York tries to avenge last year’s series sweep at the hands of their division rivals. The Jets-Raiders and Broncos-Bills matchups that close out the week should hold plenty of interest as well, especially with Sean Payton matching wits with Sean McDermott in the latter game.
| Date | Start Time | Opening NFL Week 10 odds |
| Thursday, November 9 | 8:15 p.m. ET | Carolina Panthers +2 at Chicago Bears -2 |
| Sunday, November 12 | 9:30 a.m. ET | Indianapolis Colts +5 at New England Patriots (Germany) -5 |
| Sunday, November 12 | 1 p.m. ET | Green Bay Packers +3 at Pittsburgh Steelers -3 |
| Sunday, November 12 | 1 p.m. ET | New Orleans Saints +2.5 at Minnesota Vikings -2.5 |
| Sunday, November 12 | 1 p.m. ET | Tennessee Titans -1 at Tampa Bay Buccaneers +1 |
| Sunday, November 12 | 1 p.m. ET | San Francisco 49ers -1 at Jacksonville Jaguars +1 |
| Sunday, November 12 | 1 p.m. ET | Cleveland Browns +3 at Baltimore Ravens -3 |
| Sunday, November 12 | 4:05 p.m. ET | Atlanta Falcons -1.5 at Arizona Cardinals +1.5 |
| Sunday, November 12 | 4:05 p.m. ET | Detroit Lions +2.5 at Los Angeles Chargers -2.5 |
| Sunday, November 12 | 4:25 p.m. ET | New York Giants +4.5 at Dallas Cowboys -4.5 |
| Sunday, November 12 | 4:25 p.m. ET | Washington Commanders +3.5 at Seattle Seahawks -3.5 |
| Sunday, November 12 | 8:20 p.m. ET | New York Jets -2.5 at Las Vegas Raiders +2.5 |
| Monday, November 13 | 8:15 p.m. ET | Denver Broncos +6 at Buffalo Bills -6 |
Week 11
What could well prove to be a critical Bengals-Ravens mid-November battle will kick off the slate Thursday night, and Sunday’s early-afternoon Steelers-Browns, Bears-Lions and Titans-Jaguars divisional matchups could also be critical to how those teams’ divisions play out. A Raiders-Dolphins battle is another key part of the early slate, while the second Jets-Bills clash of the season spearheads the late-afternoon window. However, the most headline-grabbing battle of the week naturally figures to be the Super Bowl LVII rematch between the Eagles and Chiefs at Arrowhead, a game KC is an early 3-point home favorite for.
| Date | Start Time | Opening NFL Week 11 odds |
| Thursday, November 16 | 8:15 p.m. ET | Cincinnati Bengals -1 at Baltimore Ravens +1 |
| Sunday, November 19 | 1 p.m. ET | Los Angels Chargers -2.5 at Green Bay Packers +2.5 |
| Sunday, November 19 | 1 p.m. ET | Dallas Cowboys -3.5 at Carolina Panthers +3.5 |
| Sunday, November 19 | 1 p.m. ET | Pittsburgh Steelers +1.5 at Cleveland Browns -1.5 |
| Sunday, November 19 | 1 p.m. ET | New York Giants -1.5 at Washington Commanders +1.5 |
| Sunday, November 19 | 1 p.m. ET | Arizona Cardinals +1.5 at Houston Texans -1.5 |
| Sunday, November 19 | 1 p.m. ET | Chicago Bears +5 at Detroit Lions -5 |
| Sunday, November 19 | 1 p.m. ET | Las Vegas Raiders +5.5 at Miami Dolphins -5.5 |
| Sunday, November 19 | 4:05 p.m. ET | Tampa Bay Buccaneers +7.5 at San Francisco 49ers -7.5 |
| Sunday, November 19 | 4:25 p.m. ET | New York Jets +3.5 at Buffalo Bills -3.5 |
| Sunday, November 19 | 4:25 p.m. ET | Seattle Seahawks -1.5 at Los Angeles Rams +1.5 |
| Sunday, November 19 | 8:20 p.m. ET | Minnesota Vikings +2 at Denver Broncos -2 |
| Monday, November 20 | 8:15 p.m. ET | Philadelphia Eagles +3 at Kansas City Chiefs -3 |
Week 12
The Thanksgiving triple-header holds plenty of promise as division rivals face off throughout Turkey Day. The Lions’ annual curtain-jerker – often perceived as the “throwaway game” of the day thanks to Detroit’s extensive struggles – now is seen in a completely different light and features what could be a pivotal NFC North battle against the Packers. The Commanders and Cowboys and 49ers and Seahawks form the remainder of the holiday card leading into the first ever Black Friday battle, which will feature the Dolphins visiting the Jets. Sunday promises some exciting action as well, considering the Browns visit the Broncos, the Chiefs are at the Raiders and the Bills drop in on the Eagles in a possible Super Bowl preview. Ravens-Chargers and Bears-Vikings clashes in primetime close out the four-day ledger.
| Date | Start Time | Opening NFL Week 12 odds |
| Thursday, November 23 | 12:30 p.m. ET | Green Bay Packers +4 at Detroit Lions -4 |
| Thursday, November 23 | 4:30 p.m. ET | Washington Commanders +5.5 at Dallas Cowboys -5.5 |
| Thursday, November 23 | 8:20 p.m. ET | San Francisco 49ers -1.5 at Seattle Seahawks +1.5 |
| Friday, November 24 | 3 p.m. ET | Miami Dolphins +2.5 at New York Jets -2.5 |
| Sunday, November 26 | 1 p.m. ET | New England Patriots +1.5 at New York Giants -1.5 |
| Sunday, November 26 | 1 p.m. ET | Carolina Panthers +1 at Tennessee Titans -1 |
| Sunday, November 26 | 1 p.m. ET | Pittsburgh Steelers +4.5 at Cincinnati Bengals -4.5 |
| Sunday, November 26 | 1 p.m. ET | New Orleans Saints vs. Atlanta Falcons |
| Sunday, November 26 | 1 p.m. ET | Jacksonville Jaguars -4.5 at Houston Texans +4.5 |
| Sunday, November 26 | 4:05 p.m. ET | Cleveland Browns +1 at Denver Broncos -1 |
| Sunday, November 26 | 4:05 p.m. ET | Los Angeles Rams -2 at Arizona Cardinals +2 |
| Sunday, November 26 | 4:25 p.m. ET | Kansas Chiefs -5 at Las Vegas Raiders +5 |
| Sunday, November 26 | 4:25 p.m. ET | Buffalo Bills +1.5 at Philadelphia Eagles -1.5 |
| Sunday, November 26 | 8:20 p.m. ET | Baltimore Ravens +2 at Los Angeles Chargers -2 |
| Monday, November 27 | 8:15 p.m. ET | Chicago Bears +3.5 at Minnesota Vikings -3.5 |
Week 13
The Seahawks-Cowboys slate opener Thursday night wraps up November and could be a key one for both teams as the stretch run begins in earnest, and the same could be true for a Cardinals-Steelers battle in the early-afternoon window Sunday. The latter portion of the ledger also holds plenty of intrigue, as we’re treated to a 49ers-Eagles NFC Championship Game rematch in Philly that the defending conference champs are early 2.5-point favorites for, a Chiefs-Packers Sunday night showdown in Lambeau and a big test for the Jaguars in the form of the visiting Bengals on Monday night.
| Date | Start Time | Opening NFL Week 13 odds |
| Thursday, November 30 | 8:15 p.m. ET | Seattle Seahawks +3.5 at Dallas Cowboys -3.5 |
| Sunday, December 3 | 1 p.m. ET | Indianapolis Colts +2,5 at Tennessee Titans -2.5 |
| Sunday, December 3 | 1 p.m. ET | Los Angeles Chargers -1.5 at New England Patriots +1.5 |
| Sunday, December 3 | 1 p.m. ET | Detroit Lions -1.5 at New Orleans Saints +1.5 |
| Sunday, December 3 | 1 p.m. ET | Atlanta Falcons +6.5 at New York Jets -6.5 |
| Sunday, December 3 | 1 p.m. ET | Arizona Cardinals +6.5 at Pittsburgh Steelers -6.5 |
| Sunday, December 3 | 1 p.m. ET | Carolina Panthers -1 at Tampa Bay Buccaneers +1 |
| Sunday, December 3 | 1 p.m. ET | Miami Dolphins -3.5 at Washington Commanders +3.5 |
| Sunday, December 3 | 4:05 p.m. ET | Denver Broncos -4 at Houston Texans +4 |
| Sunday, December 3 | 4:25 p.m. ET | Cleveland Browns -1 at Los Angeles Rams +1 |
| Sunday, December 3 | 4:25 p.m. ET | San Francisco 49ers +2.5 at Philadelphia Eagles -2.5 |
| Sunday, December 3 | 8:20 p.m. ET | Kansas City Chiefs -5.5 at Green Bay Packers +5.5 |
| Monday, December 4 | 8:15 p.m. ET | Cincinnati Bengals -1 at Jacksonville Jaguars +1 |
Week 14
A game that could have AFC wild-card implications for both teams down the line unfolds in the first Thursday night game of December, a Patriots-Steelers clash in Pittsburgh. Buccaneers-Falcons, Lions-Bears and even Panthers-Saints early-window divisional battles on Sunday have the potential for the same, while a Vikings-Raiders interconference showdown in Vegas and the latest installment of the always entertaining Bills-Chiefs series – one KC is 3.5-point favorites for in the first-look line – headline the late window. The SNF matchup doesn’t lack for star power, either, as the Eagles tangle with the Cowboys in a game that could be instrumental in deciding the fate of the NFC East.
| Date | Start Time | Opening NFL Week 14 odds |
| Thursday, December 7 | 8:15 p.m. ET | New England Patriots +1 vs. Pittsburgh Steelers -1 |
| Sunday, December 10 | 1 p.m. ET | Tampa Bay Buccaneers +2.5 at Atlanta Falcons -2.5 |
| Sunday, December 10 | 1 p.m. ET | Detroit Lions -1.5 at Chicago Bears +1.5 |
| Sunday, December 10 | 1 p.m. ET | Indianapolis Colts +9 at Cincinnati Bengals -9 |
| Sunday, December 10 | 1 p.m. ET | Jacksonville Jaguars +1 at Cleveland Browns -1 |
| Sunday, December 10 | 1 p.m. ET | Carolina Panthers +2.5 at New Orleans Saints -2.5 |
| Sunday, December 10 | 1 p.m. ET | Houston Texans +8.5 at New York Jets -8.5 |
| Sunday, December 10 | 1 p.m. ET | Los Angeles Rams +5 at Baltimore Ravens -5 |
| Sunday, December 10 | 4:05 p.m. ET | Minnesota Vikings +1.5 at Las Vegas Raiders -1.5 |
| Sunday, December 10 | 4:05 p.m. ET | Seattle Seahawks +3.5 at San Francisco 49ers -3.5 |
| Sunday, December 10 | 4:25 p.m. ET | Buffalo Bills +3.5 at Kansas City Chiefs -3.5 |
| Sunday, December 10 | 4:25 p.m. ET | Denver Broncos +3 at Los Angeles Chargers -3 |
| Sunday, December 11 | 8:20 p.m. ET | Philadelphia Eagles +1 at Dallas Cowboys -1 |
| Monday, December 11 | 8:15 p.m. ET | Tennessee Titans +7.5 at Miami Dolphins -7.5 |
| Monday, December 11 | 8:15 p.m. ET | Green Bay Packers +2.5 at New York Giants -2.5 |
Week 15
Following a marquee AFC West matchup Thursday night between the Chargers and Raiders, Jets-Dolphins and Giants-Saints battles – along with yet-to-be-scheduled Vikings-Bengals, Bears-Browns and Broncos-Lions clashes – are all Sunday games that could have plenty of postseason implications. Then, a Cowboys-Bills duel in Buffalo serves as the late-afternoon main event for the moment, while Ravens-Jaguars and Chiefs-Patriots primetime battles should make for a momentous finish to an important late-season ledger.
| Date | Start Time | Opening NFL Week 15 odds |
| Thursday, December 14 | 8:15 p.m. ET | Los Angeles Chargers -1.5 at Las Vegas Raiders +1.5 |
| Sunday, December 17 | TBD | Atlanta Falcons +1 at Carolina Panthers -1 |
| Sunday, December 17 | TBD | Denver Broncos +2 at Detroit Lions -2 |
| Sunday, December 17 | TBD | Chicago Bears +3.5 at Cleveland Browns -3.5 |
| Sunday, December 17 | TBD | Minnesota Vikings + 5 at Cincinnati Bengals -5 |
| Sunday, December 17 | 1 p.m. ET | Tampa Bay Buccaneers +3.5 at Green Bay Packers -3.5 |
| Sunday, December 17 | 1 p.m. ET | New York Giants +1 at New Orleans Saints -1 |
| Sunday, December 17 | 1 p.m. ET | Houston Texans +3 at Tennessee Titans -3 |
| Sunday, December 17 | 1 p.m. ET | New York Jets +1.5 at Miami Dolphins -1.5 |
| Sunday, December 17 | 4:05 p.m. ET | San Francisco 49ers -6.5 at Arizona Cardinals +6.5 |
| Sunday, December 17 | 4:05 p.m. ET | Washington Commanders +1 at Los Angeles Rams -1 |
| Sunday, December 17 | 4:25 p.m. ET | Dallas Cowboys +4 at Buffalo Bills -4 |
| Sunday, December 17 | 4:25 p.m. ET | Philadelphia Eagles -2 at Seattle Seahawks +2 |
| Sunday, December 7 | 8:20 p.m. ET | Baltimore Ravens +1 at Jacksonville Jaguars -1 |
| Monday, December 18 | 8:15 p.m. ET | Kansas City Chiefs -3.5 at New England Patriots +3.5 |
Week 16
It’s one of those seasons where we’re treated to an avalanche of holiday NFL action with Christmas Eve and New Year’s Eve featuring a full slate of games. In Week 16, we also have a pair of trademark late-season Saturday matchups in Bengals-Steelers and Bills-Chargers battles. Noteworthy Christmas Eve clashes from an offseason perspective include Lions-Vikings in the early portion of the day and a late-afternoon Cowboys-Dolphins affair in South Florida that figures to be important to both teams’ playoff positioning. Then, Christmas Day will have a Thanksgiving flavor, as there will also be a trio of headline battles – Raiders-Chiefs, Giants-Eagles and Ravens-49ers.
| Date | Start Time | Opening NFL Week 16 odds |
| Thursday, December 21 | 8:15 p.m. ET | New Orleans Saints +1 at Los Angeles Rams -1 |
| Saturday, December 23 | 4:30 p.m. ET | Cincinnati Bengals -2.5 at Pittsburgh Steelers +2.5 |
| Saturday, December 23 | 8 p.m. ET | Buffalo Bills -1 at Los Angeles Chargers +1 |
| Sunday, December 24 | 1 p.m. ET | Green Bay Packers -1 at Carolina Panthers +1 |
| Sunday, December 24 | 1 p.m. ET | Detroit Lions +1 at Minnesota Vikings -1 |
| Sunday, December 24 | 1 p.m. ET | Indianapolis Colts +2.5 at Atlanta Falcons -2.5 |
| Sunday, December 24 | 1 p.m. ET | Washington Commanders +5.5 at New York Jets -5.5 |
| Sunday, December 24 | 1 p.m. ET | Cleveland Browns -4 at Houston Texans +4 |
| Sunday, December 24 | 1 p.m. ET | Seattle Seahawks -2 at Tennessee Titans +2 |
| Sunday, December 24 | 4:05 p.m. ET | Jacksonville Jaguars -3.5 at Tampa Bay Buccaneers +3.5 |
| Sunday, December 24 | 4:25 p.m. ET | Arizona Cardinals +4.5 at Chicago Bears -4.5 |
| Sunday, December 24 | 4:25 p.m. ET | Dallas Cowboys +1.5 at Miami Dolphins -1.5 |
| Sunday, December 25\4 | 8:15 p.m. ET | New England Patriots +1.5 at Denver Broncos -1.5 |
| Monday, December 25 | 1 p.m. ET | Las Vegas Raiders +8.5 at Kansas City Chiefs -8.5 |
| Minday, December 25 | 4:30 p.m. ET | New York Giants +7 at Philadelphia Eagles -7 |
| Monday, December 25 | 8:15 p.m. ET | Baltimore Ravens +3 at San Francisco 49ers -3 |
Week 17
The final Thursday night game of the season – a Jets-Browns battle in Cleveland — kicks off the New Year’s slate, and the Lions-Cowboys matchup in Dallas makes for an appetizing follow-up on Saturday night. Then, there will likely be multiple teams looking to pop some champagne corks earlier than midnight in celebration of division titles or perhaps their conference’s top seed on Sunday. The day will be filled with what are expected to be playoff-relevant battles that include Dolphins-Ravens, Patriots-Bills, Chargers-Broncos and Bengals-Chiefs (Chiefs -3.5 in first-look line) contests. A Packers-Vikings NFC North clash then helps ring in 2024 on SNF.
| Date | Start Time | Opening NFL Week 17 odds |
| Thursday, December 28 | 8:15 p.m. ET | New York Jets -1 at Cleveland Browns +1 |
| Saturday, December 30 | 8:15 p.m. ET | Detroit Lions +2.5 at Dallas Cowboys -2.5 |
| Sunday, December 31 | 1 p.m. ET | Carolina Panthers +5 at Jacksonville Jaguars -5 |
| Sunday, December 31 | 1 p.m. ET | New Orleans Saints -1.5 at Tampa Bay Buccaneers +1.5 |
| Sunday, December 31 | 1 p.m. ET | New England Patriots +5.5 at Buffalo Bills -5.5 |
| Sunday, December 31 | 1 p.m. ET | Atlanta Falcons +2 at Chicago Bears -2 |
| Sunday, December 31 | 1 p.m. ET | Las Vegas Raiders -2 at Indianapolis Colts +2 |
| Sunday, December 31 | 1 p.m. ET | Los Angeles Rams +3 at New York Giants -3 |
| Sunday, December 31 | 1 p.m. ET | Arizona Cardinals +10 at Philadelphia Eagles -10 |
| Sunday, December 31 | 1 p.m. ET | San Francisco 49ers -3 at Washington Commanders+3 |
| Sunday, December 31 | 1 p.m. ET | Miami Dolphins +1 at Baltimore Ravens -1 |
| Sunday, December 31 | 4:05 p.m. ET | Pittsburgh Steelers +2 at Seattle Seahawks -2 |
| Sunday, December 31 | 4:25 p.m. ET | Cincinnati Bengals +3.5 at Kansas City Chiefs -3.5 |
| Sunday, December 31 | 4:25 p.m. ET | Los Angeles Chargers +1 at Denver Broncos -1 |
| Sunday, December 31 | 8:20 p.m. ET | Green Bay Packers +2.5 at Minnesota Vikings -2.5 |
Week 18
As customary, the final week of the regular season only has set opponents at this juncture but no game times. All contests are divisional clashes and take place on Sunday, January 8th. Some of the games that appear likeliest, from a preseason perspective, to play a role in deciding division titles/playoff berths/postseason seeding include Seahawks-Cardinals, Steelers-Ravens, Browns-Bengals, Vikings-Lions, Chiefs-Chargers, Bills-Dolphins, Jets-Patriots and Eagles-Giants clashes. It’s also the one definite “wait and see” betting slate of the season, as there’s simply no telling what each team’s individual playoff scenario and corresponding personnel usage will be until much closer to the ledger actually unfolding.
| Date | Start Time | Opening NFL Week 18 odds |
| Sunday, January 7 | TBD | Chicago Bears +2 at Green Bay Packers -2 |
| Sunday, January 7 | TBD | Minnesota Vikings +2.5 at Detroit Lions -2.5 |
| Sunday, January 7 | TBD | Dallas Cowboys -3 at Washington Commanders +3 |
| Sunday, January 7 | TBD | Philadelphia Eagles -2.5 vs. New York Giants +2.5 |
| Sunday, January 7 | TBD | Atlanta Falcons +2.5 at New Orleans Saints -2.5 |
| Sunday, January 7 | TBD | Tampa Bay Buccaneers +2.5 at Carolina Panthers -2.5 |
| Sunday, January 7 | TBD | Pittsburgh Steelers +3.5 at Baltimore Ravens -3.5 |
| Sunday, January 7 | TBD | Cleveland Browns +4 at Cincinnati Bengals -4 |
| Sunday, January 7 | TBD | Buffalo Bills +1.5 at Miami Dolphins -1.5 |
| Sunday, January 7 | TBD | Houston Texans +1.5 at Indianapolis Colts -1.5 |
| Sunday, January 7 | TBD | New York Jets -1 at New England Patriots +1 |
| Sunday, January 7 | TBD | Jacksonville Jaguars -2.5 at Tennessee Titans +2.5 |
| Sunday, January 7 | TBD | Los Angeles Rams +6 at San Francisco 49ers -6 |
| Sunday, January 7 | TBD | Seattle Seahawks -4.5 at Arizona Cardinals +4.5 |
| Sunday, January 7 | TBD | Kansas City Chiefs -2 at Los Angeles Chargers +2 |
| Sunday, January 7 | TBD | Denver Broncos -1 at Las Vegas Raiders +1 |
