NFL Divisional Betting Preview: Dallas Cowboys At San Francisco 49ers Odds

Written By Evan Scrimshaw on January 19, 2023 - Last Updated on January 22, 2023
cowboys 49ers odds

In NFL Playoffs odds, the final game of the divisional round sees the Dallas Cowboys heading to the Bay Area to play the San Francisco 49ers in a rematch of a 2021 Wild Card game. Primary markets have the Niners as , with the Big D on the moneyline to win the game. The over/under is .

With the Niners knocking out Dallas on route to an NFC Championship Game appearance, San Fran would like to repeat that success, while the Cowboys are looking for a better end to this story. Kickoff is Sunday at 6:30 p.m. ET. Click on the odds anywhere in this post to bet now.


Go to our weekly post for the best available prices in your state for all NFL Divisional odds.

If you’re looking at spreads for Cowboys at 49ers odds, getting an extra half point on either side can make or break the difference, and getting the best side of totals markets can be crucial as well. When it comes to moneyline betting, you always want to get the best number possible – all three things that the easy comparison points of the odds table allow.

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Cowboys at 49ers Player Props

The props tool enables bettors to effectively track Cowboys at 49ers odds across sportsbooks for every player prop, to make sure that bettors aren’t missing out on a better total, or a better value, on a player prop.

Whether it’s getting a total you want to bet an Over on five yards lower, or a line where you have to pay less juice, the Props tool enables bettors to make sure they’re not missing out on the best available SNF odds.

Cowboys vs. Niners Betting News & Angles

49ers Vs. Cowboys Weather

A high temperature of 57 degrees Fahrenheit, with broken clouds and 4 mph winds, is the forecast for Levi’s Stadium on Sunday (as of 9:26 AM on January 19).

49ers Vs. Cowboys Injury Report

San Francisco Injuries

PlayerPos.InjuryStatusAvg. Snap Count
Jimmy GaroppoloQBFootQuestionable55.8
Jauan JenningsWRAnkleQuestionable34.8
Javon KinlawDTKneeQuestionable31.0
Jauan JenningsWRAnkleQuestionable30.0
Javon KinlawDTKneeQuestionable28.5
Ambry ThomasCBAnkleQuestionable11.9

Dallas Injuries

PlayerPos.InjuryStatusAvg. Snap Count
Tyron SmithOTKneeProbable74.0
Tyron SmithOTKneeProbable69.3
Demarcus LawrenceDEFootQuestionable46.0
Demarcus LawrenceDEFootQuestionable41.0
Jason PetersOTHipQuestionable33.0
Trayvon MullenCBIllnessProbable24.9
Jason PetersOTHipQuestionable20.1

49ers Offense Vs. Cowboys Defense

49ers OffenseStats (Rank)Cowboys Defense
26.5 (6)Points/Gm20.1 (5)
0.4 (2)Points/Play0.3 (1)
365.6 (5)Yards/Gm330.2 (12)
226.8 (13)Pass Yards/Gm200.9 (8)
138.8 (8)Rush Yards/Gm129.3 (22)
5.9 (4)Yards/Play5.1 (7)
7.5 (4)Yards/Pass6.2 (8)
4.7 (8)Yards/Rush4.4 (15)
45.0% (6)3rd Down %37.7% (9)
54.0% (18)Red Zone %52.0% (9)
17 (3)Turnovers33 (1)
31 (6)Sacks54 (3)

Cowboys Offense Vs. 49ers Defense

Cowboys OffenseStats (Rank)49ers Defense
27.5 (4)Points/Gm16.3 (1)
0.4 (2)Points/Play0.3 (1)
354.9 (11)Yards/Gm300.6 (1)
219.8 (14)Pass Yards/Gm222.9 (20)
135.2 (9)Rush Yards/Gm77.7 (2)
5.4 (15)Yards/Play5.0 (3)
6.7 (10)Yards/Pass6.4 (11)
4.3 (18)Yards/Rush3.4 (1)
45.5% (5)3rd Down %39.0% (16)
71.4% (1)Red Zone %56.8% (20)
23 (17)Turnovers30 (2)
27 (4)Sacks44 (10)

Cowboys At 49ers Betting Insights

Why The Cowboys Can Cover The Spread

Dallas does have the 2nd best defense in the regular season per DVOA and were able to stifle the Bucs until garbage time last week. They are the best defense Brock Purdy has faced, and Dak Prescott finally looked better last week.

If Purdy finally shows himself to be the inauspicious talent we all thought he was after being drafted as Mr. Irrelevant, would anyone actually be shocked?

Why The 49ers Can Cover The Spread

As absurd as it is to think about, Brock Purdy is currently playing like one of the best QBs in the league. This fact can’t be denied just because people do not believe Purdy is that rawly talented, but on merit he is Top 5 by two leading advanced QB metrics.

Throw in the fact that Deebo Samuel is finally healthy, Shanahan has been able to use his whole bag of tricks, and the fact that the Niners have two days rest advantage on the Niners, this is setting up very well for the Niners.

Reasons to bet the Over

The Niners are a train at this point, having scored 30+ in all but one game in the Purdy era. Yes, the Cowboys are the biggest threat of the Purdy era defensively, but the Shanahan era Niners have always been able to scheme open quick throws to receivers in space, which should be abailable even against the Cowboys.

If the Niners score at or near their recent record, the Cowboys just need to score 20 to hit this Over, which between garbage time, a shootout, or a defensive score, is all in play.

Reasons to bet the Under

These two teams ranked No. 1 and No. 2 by DVOA defense and both have elite pass rushers, which means drives can always end short. Throw in the chance of both QBs making questionable decisions under duress, and this total could easily come in.

Cowboys At 49ers Matchups To Watch For

Dak Prescott Interceptions: Over/Under /

Dak has been a turnover machine in recent weeks, with 11 in his last 7 regular season games. He was able to avoid a big mistake against the Buccaneers, but against the ferocious Niners defensive line, Dak is going to have to make split second decisions in this game, and those are ending badly these days.

Final Thoughts

A bet on the Cowboys here is, in effect, a bet on the Niners offense not being able to score enough points in this game, and it’s not a compelling pitch. In reality, what a Cowboys bet is betting on is Brock Purdy being a radically different quarterback than he has been so far in his NFL career.

Since Purdy came in against the Dolphins, he is 4th in EPA/Play and 5th by the EPA/Completion Percentage Above Expected (CPOE) combined metric. Dak is 13th and 14th by those metrics respectively. On actual performance, Brock Purdy is outplaying Dak Prescott right now.

Whatever we think of these offenses in the abstract, the Niners offense – 6th by DVOA in the regular season, 4th by PFF – is a sight better than the Cowboys’ 15th ranked Offense. With these defenses 1st and 2nd by DVOA respectively, it comes down to the offenses.

More importantly, it comes down to Kyle Shanahan versus whatever two headed monster of Kellen Moore and Mike McCarthy’s influence exists in Dallas, and that’s an easy choice.

Niners are so clearly the better team, only laying a bit more than what you’d expect on an neutral field.

Good luck betting Cowboys at 49ers odds.

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