College Football Picks and Parlays for Week 6: Best Bets for Big Games

With so many big games this Saturday, let’s dive into our top college football picks and parlays for Week 6.

All parlay odds come from some of the top US sportsbooks.

College Football Picks and Parlays

College Football Parlay #1: Ducks Strut Their Feathers

No. 21 UCLA (4-0) puts their perfect record on the line as they head up the coast to Eugene to face No. 13 Oregon (3-1).

FanDuel Sportsbook has Oregon as an 11.5-point favorite, with a total of 59.5.

• Oregon to win and cover: Oregon is coming off a bye and is coming off an impressive win in their last game, handing USC their only loss in a 41-27 road win. UCLA is undefeated, but are they for real? They have lit up the scoreboard this season, but both of their Big 10 wins have come against teams with losing records. Eugene is a tough place for opponents to play, and the Ducks will roll the Bruins in this one.
• Over 59.5 points: Oregon ranks fourth in the nation in scoring at 47.5 ppg, and UCLA ranks seventh (44.8 ppg). The Bruins rank in the top 40 in opponents’ ppg, but they haven't played a tough schedule. Don’t expect much defense in this game, and in what looks like a shootout, the Over is the pick.

The odds for this parlay are +268, so a $100 bet would pay $368, for a $268 profit.

NCAAF Parlay: Oregon to cover at -11.5 and Over 59.5 points: (+264, FanDuel)

If you need any help with parlays we have an extensive parlay betting guide.

College Football Parlay #2: Top Two Teams Come Through

The two top-ranked teams in the nation have big rivalry games on Saturday: No. 1 Texas faces Oklahoma in the Red River Rivalry, and No. 2 hits the road to face No. 6 Alabama.

DraftKings Sportsbook has Texas as a 7.5-point favorite with a total of 39.5 and Georgia as a 1.5-point underdog with a total of 51.5.

• Texas to cover: The Longhorns (4-0) are coming off a win over a ranked Tennessee team, and while Arch Manning has not lit it up and the team only ranks 55th in scoring (33.3 ppg), they rank 12th in opponents’ scoring (13.3 ppg). They will win and cover in this game against a 2-2 Oklahoma team that only ranks 130th in the nation in passing yards per game and 131st in rushing yards per game.
• Georgia to win with moneyline (+102): With the short spread, I’m taking the moneyline to get better odds. Both UGA and Bama are 5-0, and the Bulldogs have beaten their opponents, but they average 38 PPG. Both teams are stacked, but Georgia has the better defense. The Bulldogs lost at home to the Tide last season but beat them in the SEC title game, and they'll hand Bama a home loss in this game, which is set up to be a classic.

The odds for this parlay are +286, so a $100 bet would pay $386, for a $286 profit.

NCAAF Parlay: Texas to cover the spread and Georgia with moneyline: (+286, DraftKings)

Before making a parlay at the best US sportsbooks check out the bonuses and promotions available to pad your NCAAF betting bankroll.

College Football Parlay #3: USC Bounces Back

No. 19 USC (5-1) is coming off a win and faces Penn State (3-2), who have lost two in a row.

BetMGM Sportsbook has Penn State as a slight 1.5-point favorite with the total sitting at 54.5.

• USC and the moneyline: The moneyline gives better odds for the Trojans, who got over their loss to a ranked Oregon team by beating Washington in their last game. They have one of the nation's better passing offenses, and while they haven't fared well on the East Coast under Lincoln Riley, they will win this game against a Nittany Lions team that has lost two in a row to unranked teams and gave up 34 points in its last game.
• Under 54.5 points: Penn State lost their last game because they were mauled on the ground, giving up over 400 rushing yards. They have the second-ranked pass defense but haven't faced a great passing team. USC will air it out, but they will also run more than usual against a Nittany Lions team that ranks only 97th in run defense. Both teams will run, which will lead to a lower-scoring affair.

The odds for this parlay are +282, so a $100 bet would pay $382, for a $282 profit.

NCAAF Parlay: USC and the moneyline and Under 54.5 points: (+282, BetMGM)

The best NCAAF betting sites will have the latest odds and many betting markets.

College Football Parlay #4: Big Players Go Big

Here is a three-leg parlay with player props from DraftKings.

• King Miller 70+ rushing yards: Miller leads USC with 493 rushing yards, and he has rushed for over 70 yards in four of the five games. While the Trojans are known for a pass-first offense, King will get touches against a Penn State team that ranks 97th in the nation in rushing defense and gave up 413 rushing yards in its last game.
• Noah Fifita 280+ passing yards: Arizona QB Fifita has the 11th most passing yards in college football and is poised for a big game Saturday facing West Virginia. He has thrown for over 280 yards in his last three games and will face a Mountaineers pass defense ranked third-to-last in the nation, giving up an average of 317.8 passing yards per game.
• Turbo Richard 90+ rushing yards: How can you not put a running back named Turbo on a parlay? The Indiana RB ranks ninth in the nation in rushing yards, has rushed for over 100 yards in three of his last four games, and in the last game had a season-high 204 rushing yards. While he will face a Nebraska team ranked 21st in the nation in run defense, they gave up over 140 rushing yards in the last game.

The odds for this parlay are +508, so a $100 bet would pay $608, for a $508 profit.

NCAAF Parlay: King Miller 70+ rushing yards, Noah Fifita 280+ passing yards, Turbo Richard 90+ rushing yards: (+508, DraftKings)

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