Portland Trail Blazers vs. San Antonio Spurs Odds, Picks & Predictions - Game 5

Written By Chris Kubala | Published at April 28, 2026
Apr 24, 2026; Portland, Oregon, USA; San Antonio Spurs guard De'aaron Fox (4) shoots the ball over Portland Trail Blazers forward Kris Murray (24) during the second half during game three of the first round of the 2026 NBA Playoffs at Moda Center. Mandatory Credit: Jaime Valdez-Imagn Images

It’s the continuation of a first-round Western Conference series as the seventh-seeded Portland Trail Blazers make the trip to clash with the second-seeded San Antonio Spurs in Game 5 Tuesday night and we have things covered with our Trail Blazers vs. Spurs prediction. San Antonio took Game 1, 111-98, at home Sunday to draw first blood in the set. They covered the line as a 12.5-point favorite in that contest. Portland responded with a 106-103 road win in Game 2 Tuesday night. The Trail Blazers won outright as a 10.5-point underdog.

In Game 3, San Antonio rallied for a 120-108 win Friday night, covering as a 1.5-point favorite. They followed that up with a 114-93 triumph in Game 4 Sunday night, covering the line as 5.5-point favorite.

In the all-time playoff series between the teams, San Antonio has won three of the four previous series. The Spurs own a 17-7 advantage in head-to-head playoff victories. Let’s break down this Trail Blazers vs. Spurs matchup.

Trail Blazers Seek to Force Game 6

Portland played solid basketball for the first half but basketball is a 48-minute contest, not 24. As a result, the Trail Blazers now trail 3-1 in the series and need a win to send the series back home for Game 6. In Game 4, Portland led by two after the opening quarter, by as many as 19 and held a 17-point margin at the half. The Trail Blazers crumbled in the second half as they were outscored 73-35 in the second half to take the loss. Deni Avidja led Portland with 26 points and seven rebounds in the loss.

During the postseason, the Trail Blazers are tied for 13th in the league in scoring offense with 101.3 points per game. Portland is 12th in the league in rebounding with 41.3 boards a contest. They are 15th in assists as they hand out 20.8 assists per game this season. The Trail Blazers are 13th in scoring defense by allowing 112 points per night. Deni Avidja is leading the team with 22.3 points, 6.8 rebounds and five assists per game this postseason. Jrue Holiday kicks in 18.5 points plus 7.3 assists per contest.

Portland is 12th in the league in field goal percentage as they shoot 41.7% from the field as a team this postseason. The Trail Blazers are tied for 6th in the league in threes per game as they hit 11.8 triples per game. They are 13th in three-point percentage as they hit 32.4% from beyond the arc. Portland is above average at the free throw line, ranking 8th by converting 75.9% of their attempts this season.

Key Injury Report for Trail Blazers:

Spurs Looking to Close Things Out

San Antonio shrugged off a sluggish first half to bury Portland after intermission en route to the win. The Spurs now return home with a 3-1 series advantage as they take the floor here for Game 5. In Game 3, San Antonio found themselves in a 17-point hole at the half before getting in gear. The Spurs outscored the Trail Blazers 33-16 in the third quarter to tie the game. San Antonio outscored 40-19 in the final stanza to win going away. De’Aaron Fox led the Spurs with 28 points, six rebounds and seven assists as one of four players in double figures.

In the postseason, the Spurs are 4th in the league in scoring offense as they average 112 points per game on the year. San Antonio is tied for 6th in rebounding by grabbing 45 boards a night. They are 6th in the league in assists by handing out 24 dimes per contest. The Spurs are tied for 3rd in the league in scoring defense as they give up an average of 101.3 points per game. Victor Wembanyama is leading the team with 22.3 points plus 7.3 rebounds and 3.3 blocks this postseason. De’Aaron Fox (20 points, 6.3 assists) and Stephon Castle (21 points, 4.3 rebounds, 6.3 assists) provide additional firepower

San Antonio is 4th in the league in field goal percentage as they shoot 47.1% from the floor on the year. The Spurs are 4th in threes per game as they connect on 13 triples a night. They are 1st in three-point percentage by shooting 42.3% from beyond the arc. San Antonio has been slightly above average at the charity stripe, ranking 5th in the league by converting 78.3% of their attempts.

Key Injury Report for Spurs:

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Trail Blazers vs. Spurs Prediction

Portland had San Antonio reeling into the third quarter of Game 3. The Trail Blazers followed up by doing that again in Game 4 as they were up 17 at the half. Portland has faded badly in the second half of those two contests. The Spurs outscored the Trail Blazers 61-43 in the second half of Game 3 and 73-35 in Game 4. San Antonio is at home for this contest as the return of Wembanyama in Game 4 was a major boost to them. Playing at home with an opportunity to win the series and get rest ahead of the second round, San Antonio takes care of business.

Our Prediction: Spurs -11.5 (DraftKings, -105)

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