Philadelphia 76ers vs. New York Knicks Odds, Picks & Predictions - Game 1

Written By Chris Kubala | Published at May 4, 2026
Apr 30, 2026; Atlanta, Georgia, USA; New York Knicks forward Og Anunoby (8) drives on Atlanta Hawks forward Mouhamed Gueye (18) in the second quarter during game six of the first round of the 2026 NBA Playoffs at State Farm Arena. Mandatory Credit: Brett Davis-Imagn Images

The second round of the NBA playoffs start in earnest with an Eastern Conference battle as the seventh-seeded Philadelphia 76ers take on the third-seeded New York Knicks in Game 1 of their best of seven series Monday night and we have you covered with our 76ers vs. Knicks prediction. Philadelphia advanced by downing Boston 109-100 Saturday night in Game 7. Therefore, they won the series four games to three. They won outright as a 3.5-point underdog. New York pulverized Atlanta 140-89 on the road in Game 6 Thursday night. The Knicks covered the line as a 3.5-point favorite in the contest.

In the all-time playoff series between the teams, Philadelphia has won five of the nine previous series. The 76ers own a 23-16 advantage in head-to-head playoff victories. Let’s break down this 76ers vs. Knicks matchup.

76ers Try to Carry Momentum to Big Apple

Philadelphia was down 3-1 in their series with Boston before rallying. The 76ers took the final three games, two of them in Boston, to win the series 4-3. In Game 7, Philadelphia scored the first nine points and led by as many as 15 in the opening quarter. The 76ers led 32-19 after one quarter, trailed by one in the second quarter and led by five at intermission. Philadelphia led the rest of the way to earn the win and take the series. Joel Embiid paced the 76ers with 34 points, 12 rebounds and six assists in the win.

In the playoffs, the 76ers are 10th in the league in scoring offense with 103.7 points per game. The 76ers are 12th in rebounding as they collect 41.1 rebounds per contest. They are 11th in assists by dishing out an average of 21.7 dimes a night. Philadelphia is 9th in the league in scoring defense as they allow an average of 106.6 points a contest. Tyrese Maxey is a solid option for the 76ers as he puts up 26.9 points and 6.6 assists per game this postseason. Joel Embiid (29 points, nine rebounds, seven assists) and Paul George (17.4 points) are good secondary scoring options.

Philadelphia is tied for 8th in the league in field goal percentage as they shoot 44.6% from the floor as a team. The 76ers are tied for 7th in threes per game as they drain 11.6 triples a contest. They are 6th in three-point shooting by connecting on 35.2% of their attempts from beyond the arc. Meanwhile, Philadelphia stands 3rd in the league in free throw shooting as they convert 81.3% of their attempts at the stripe.

Key Injury Report for 76ers:

Knicks Shoot to Defend Home Floor

New York took the final three games of their first-round series with the Hawks, winning Game 6 in blowout fashion on the road Thursday, to advance. The Knicks look to continue their push as they open this series at home. Against Atlanta, New York trailed 9-5 early but outscored the Hawks 35-6 the rest of the quarter for a 40-15 advantage. Following that, the Knicks never looked back from there, leading by 47 at the half. New York led by as many as 61 in the contest en route to the win. In addition, the Knicks shot a blistering 58.8% from the floor in the victory. OG Anunoby paced the Knicks with 29 points in the win.

In the postseason, the Knicks are 2nd in the league in scoring offense with 117.8 points per contest entering this game. New York is 4th in the league in rebounding as they collect 45.8 rebounds per game. They are 6th in the league in assists by dishing out 24.2 dimes per contest. The Knicks are 5th in the league in scoring defense by allowing 100.3 points per contest. Jalen Brunson (26.3 points, 6.2 assists) is the team’s leading scorer. OG Anunoby (21.5 points, 8.7 rebounds0 and Karl-Anthony Towns (18.7 points, 11 rebounds, six assists) provide a good secondary punch for the Knicks in the playoffs.

New York is 1st in the league in field goal percentage as they shoot 49.9% from the floor as a team. In addition, the Knicks are 6th in the league in threes per game as they knock down 11.8 triples a night. Meanwhile, they are 3rd in three-point shooting by hitting 38% of their attempts from beyond the arc. New York is solid at the charity stripe, ranking 5th in the league by cashing in 77.4% of their attempts.

Key Injury Report for Knicks:

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76ers vs. Knicks Prediction

There is a ton of history between these teams and there are sure to be some heated moments. The Knicks have home court advantage here, although the road team won all four regular season games this season. Both teams found something in the late stages of their opening round series running through their big men. Towns turned in a pair of triple-doubles against the Hawks while Embiid handed out 28 assists in four games. The Knicks have a rest advantage here, which works in their favor. On the other hand, four starters for the 76ers logged at least 39 minutes in Game 7. Therefore, look for New York to take advantage and wear down the 76ers to take Game 1.

Our Prediction: Knicks -7.5 (FanDuel, -106)

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