MNF Week 6 NFL Player Props: Uncovering the Hidden Value in Pair of Games
Written By Nick Crain | Last Updated at October 13, 2025
Monday Night Football brings a pair of matchups with plenty of NFL Week 6 player prop value as the Atlanta Falcons host the Buffalo Bills to start, followed by the Washington Commanders hosting the Chicago Bears.
Injuries, defensive strengths and game flow all set the stage for intriguing betting angles on both sides of the ball. Both of these contests will bring competitive team football, but the player props are the most interesting, especially with the latest sportsbook promos.
With that in mind, here are the best prop bets for Week 6 of Monday Night Football action and where the lines provide an edge today.
Caleb Williams o24.5 Rushing Yards
Odds: -110 (via bet365)
There's no question that Williams is at his best when he's able to make plays with his legs and keep the defense guessing. Especially in a game like this against a stout defensive line that the Commanders have, Williams could be scrambling and ultimately having to rush for first downs if he's flushed out of the pocket.
Bijan Robinson o32.5 Receiving Yards
Odds: -115 (via BetMGM)
Robinson is one of the most dynamic running backs in the NFL, with his ability to not only run the ball but also catch it and make plays. With one single catch and run, Robinson is capable of cashing this over on receiving yards tonight, even against a good Bills defense. He has the skill of a wide receiver as a running back.
Rome Odunze Anytime TD Scorer
Odds: +130 (via Caesars Sportsbook)
Odunze entered this week as one of the NFL's top TD catchers, with five to his name through five weeks. Given he's Caleb Williams' top target when it comes to finding the endzone, getting him at plus value makes this a great bet. If Chicago can get the offense going, Odunze will finish.
James Cook 2+ Touchdowns
Odds: +375 (via Caesars Sportsbook)
Cook is a touchdown machine again this season. He's logged five already, after scoring 18 total a year ago. Finding the endzone twice in the same game is no easy task, but he's already done it once this season. In fact, Cook has scored in every game this season other than last week, which is why he'll be extra motivated to make up for it tonight.
Bet $1, Double your Winnings on your Next 20 Wagers. Up to $25 Max Bet Per Boost Both of these games could truly go either way, no matter what each team's record is. It's the NFL, and anything can happen on any given night. Because of that, betting on player props can be an interesting alternative for the two-game Monday Night Football slate.
Always compare prices across books before placing your wagers, but these are the props that carry the most value for Monday Night Football. Finding the best value can make the difference between a bad beat and cashing a bet. Be mindful of late injury updates and line movement leading up to kickoff, as they can shift projections dramatically.
All Odds as of 11:59 p.m. ET on Oct. 12
Featured Image Mandatory Credit: Syndication: Dale Zanine-Imagn Images
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