MLB Pitcher Props for Sep. 14: Guardians' Williams Piles Up K's

There are just two weeks remaining in the regular season. The playoff races are in full swing and every game has meaning at this point of the year. There’s a 10-game slate on the diamond Monday, starting at 6:40 PM ET on the shores of Lake Erie. The Chicago White Sox are on the road as they open a pivotal AL Central series with the Cleveland Guardians at Progressive Field.
In the American League, three teams are within three games of the final wild card spot. Meanwhile, in the National League, the Padres own a 2.5-game edge on the Diamondbacks for the final wild card spot.
We’ve taken a look at the matchups on the docket and found the best options are as far as betting on MLB pitcher props on the board. Read on to get our breakdown of the top plays for Monday, Sept. 14 on the diamond as we try to put some cash in your pocket.
Best MLB Pitcher Strikeout Bets Today: Player Props for September 14
Gavin Williams, Guardians Over 7.5 Strikeouts (-138, FanDuel)
Williams quietly is the ace of the Guardians’ rotation this season. He enters this start 13-7 with a 3.78 ERA and a 1.095 WHIP over 169 innings of work. In addition, Williams is second in the majors with 228 strikeouts on the year. Among current White Sox hitters, he has recorded more strikeouts (26) than hits allowed (16) in 73 at-bats. Meanwhile, if that wasn’t enough, the White Sox strike out at the fifth-highest rate in the majors with 9.17 whiffs per game. That number climbs to 9.51 strikeouts a game on the road. Williams picked up 11 strikeouts over six innings in his last start. He has 21 strikeouts over 15.1 innings in three starts against the White Sox this season. This one may turn out in similar fashion. Take the over at FanDuel on this prop.
Tarik Skubal, Dodgers Over 7.5 Strikeouts (-106, FanDuel)
Skubal was dealt to the Dodgers from the Tigers at the trade deadline, bolstering the rotation of the two-time defending champs. He comes in 9-7 with a 2.84 ERA, a 0.974 WHIP, 24 walks and 164 strikeouts over 139.2 innings of work. Skubal missed some time earlier this season after elbow surgery but rebounded nicely. Cincinnati faded in the second half of the season. The Reds strike out at the highest rate (9.56 per game) in baseball. That number climbs to 9.74 strikeouts a night at the Great American Ball Park. Meanwhile, current Reds hitters are a combined 8-of-57 (.140) with 19 strikeouts against Skubal. He goes over his strikeout prop here.
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Sandy Alcantara, Marlins Over 17.5 Outs Recorded (-157, DraftKings)
Alcantara bounced back this season after a rough 2025 that saw him post a 5.36 ERA over 174.2 innings of work. He enters this start 13-10 with a 3.78 ERA, a 1.215 WHIP, 55 walks and 143 strikeouts on the year. In addition, Alcantara logged a league-high 200 innings of work entering this one. He cracked the 200-inning plateau for the third time in his career. Alcantara is a bastion of consistency as he’s worked at least six frames in 26 of his 31 starts. Meanwhile, he worked 5.2 innings in two of his other four outings. Facing a Mets’ lineup that entered Monday tied for 18th in the majors with 4.42 runs a game works in his favor. Look for another good start here.
Reid Detmers, Angels Over 17.5 Outs Recorded (-155, DraftKings)
Detmers, despite improvement in most metrics, hasn’t had it show up in the win column this season. He was nearly dealt at the trade deadline but ended up staying put. On the year, he is 5-8 despite a 3.32 ERA, a 1.036 WHIP, 45 walks and 191 strikeouts over 168 innings. Detmers is just 1-5 at home though he has a 3.21 ERA and 114 strikeouts over 98 innings of work in 16 starts. Meanwhile, he faces a Seattle squad that is 28th in the majors with 4.06 runs per game. Detmers threw 6.2 scoreless innings in his lone start against the Mariners this year. In addition, he worked at least six innings in six straight starts. He works deep enough here to cash the prop.