MLB Home Run Props and Predictions Today: Top Player Props for Sept. 15
We're back with another round of the best MLB home run props for today's action.
Tuesday’s baseball slate has a few left-handed hitters in strong matchups against vulnerable right-handed pitchers.
Best MLB Home Run Props Today (Sept. 15)
I’m targeting three very talented stars in excellent spots to do damage.
Let’s dive into the best MLB home run props for Sept. 15!
Home Run Prediction #1: Max Muncy
We’ll start at Great American Ball Park, where the Reds host the Dodgers at 6:40 p.m. ET. Max Muncy to hit a home run on DraftKings Sportsbook is my favorite MLB home run prop for Tuesday.
Rhett Lowder gets the ball for Cincinnati, and this is a matchup I want to attack with left-handed power. The right-handed pitcher has allowed a .232 expected ISO to left-handed hitters this season while striking out just 18% of them.
The underlying profile is concerning too. According to Baseball Savant, Lowder ranks in the 13th percentile in barrel rate allowed and has given up a high average exit velocity. That is a dangerous formula against any left-handed power hitter, especially one playing in a hitter-friendly environment like Great American Ball Park.
Muncy has been locked in this season. He owns a .246 ISO against right-handed pitching and has slugged north of .600 so far in September. He has hit 28 home runs this year, with 22 coming against right-handed pitching.
That split is the key. Muncy gets a right-hander who has struggled to miss left-handed bats and has allowed too much loud contact. In a ballpark that gives power hitters plenty of room for error, Muncy is in a great spot to go deep. The Dodgers are obviously a scary lineup to navigate through, and Muncy should see pitches to hit.
Best Bet: Max Muncy To Hit A Home Run DraftKings, +359
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170,000 GC + 7 SC Home Run Prediction #2: Ben Rice
Next, we’ll head to Target Field, where the Twins host the Yankees at 7:40 p.m. ET. Ben Rice to hit a home run on DraftKings is another MLB home run prop I’m targeting Tuesday.
It seems like I bet Rice quite often, and that's because I do! It turns out he is very, very good at hitting a baseball.
Bailey Ober gets the ball for Minnesota, and he is another right-hander I want to attack with left-handed power. Ober has allowed a .228 expected ISO to left-handed hitters this season and has struck out only 13% of them.
That is a lot of contact for a pitcher who does not have much margin for error. According to Baseball Savant, Ober ranks in the literal first percentile in fastball velocity. He also ranks in only the ninth percentile in ground-ball rate allowed and gives up plenty of barrels.
Ober has allowed 12 home runs to left-handed hitters, but the underlying profile matters even more here. He gives up hard contact through the air, and he does not generate many strikeouts against lefties.
We have backed Rice plenty of times this season, and this is another spot where the matchup aligns with his profile. He gets the platoon advantage against a soft-tossing right-hander who has struggled to keep left-handed hitters from doing damage.
Best Bet: Ben Rice To Hit A Home Run DraftKings, +281
Before locking in a home run prop today, it is worth comparing prices across the top MLB betting sites.
New DraftKings Customer: SPEND $5, GET $200 IN BONUSES Home Run Prediction #3: Dom Canzone
Finally, we’ll head to Anaheim, where the Angels host the Mariners. Dom Canzone to hit a home run on DraftKings is my final MLB home run prop for Tuesday.
Ryan Johnson is set to take the mound for the Angels, and he has been another pitcher to target with left-handed power in 2026. Johnson has allowed worse than a .200 ISO to left-handed hitters this season, creating a strong matchup for Canzone.
Canzone has enjoyed a true breakout campaign, and his power against right-handed pitching has been a big part of it. He owns a .227 ISO against righties and has posted excellent advanced metrics. Canzone has consistently hit the ball with authority this year, and anytime the Mariners are away from T-Mobile Park, I'm interested in backing their hitters.
Canzone gets the platoon advantage against a right-hander with a poor track record against lefties, and the matchup gives Canzone a clear path to big-time damage.
Best Bet: Dom Canzone To Hit A Home Run DraftKings, +465
Before you bet, compare current pricing across the best sports betting sites, particularly when looking at pitching markets and home run props.
Good luck, and let’s cash some MLB best bets today.
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