MLB Today’s Best Bets for October 16th: Home Run Picks & Top Player Props

Written By Blaise Bourgeois | Published at October 16, 2025
Sep 26, 2025; Seattle, Washington, USA; Los Angeles Dodgers designated hitter Shohei Ohtani (17) strikes out against Seattle Mariners pitcher George Kirby (68) during the first inning at T-Mobile Park. Mandatory Credit: John Froschauer-Imagn Images
MLB: Los Angeles Dodgers at Seattle Mariners

The MLB postseason took another thrilling turn last night in ALCS Game 3 after the Toronto Blue Jays came back from an early two-run deficit to rout the Seattle Mariners 13-4. In doing so, they avoided a virtually inescapable 3-0 hole and have brought the series back to 2-1.

Tonight, the Milwaukee Brewers will look to do the same in NLCS Game 3, as the Los Angeles Dodgers have taken a 2-0 series lead. Sportsbooks and betting apps will have a busy night as playoff baseball coincides with an AFC North clash on Thursday Night Football, as Joe Flacco and the Cincinnati Bengals play host to Aaron Rodgers and the Pittsburgh Steelers.

Without further ado, let's bring you MLB's best bets today. We'll feature some tasty value and a player prop that simply cannot be ignored.

Milwaukee Brewers @ Los Angeles Dodgers

BetMGM Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Bet Now BetMGM Promo
Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) Call 877-8-HOPENY or text HOPENY (467369) (NY) Call 1-800-327-5050 (MA) 21+ only. Please Gamble Responsibly. Call 1-800-NEXT-STEP (AZ), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). Rewards are non-withdrawable bonus bets that expire in 7 days. In partnership with Kansas Crossing Casino and Hotel. See BetMGM.com for Terms. US promotional offers not available in DC, Mississippi, New York, Nevada, Ontario, or Puerto Rico.

DraftKings New Customers: Bet $5+ Get $200 in Bonus Bets Instantly
GAMBLING PROBLEM? CALL 1-800-GAMBLER or 1-800-MY-RESET, (800) 327-5050 or visit gamblinghelplinema.org (MA). Call 877-8-HOPENY/text HOPENY (467369) (NY). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD), 1-800-981-0023 (PR). 21+ and present in most states. (18+ DC/KY/NH/PR/WY). Void in NH/OR/ONT/PR. Eligibility restrictions apply. On behalf of Boot Hill Casino (KS). Pass-thru of per wager tax may apply in IL. 1 per new customer. Min. $5 first-time bet req. Max. $200 issued as non-withdrawable Bonus Bets that expire in 7 days (168 hours). Stake removed from payout. Plus, upon qualifying bet placement, get 1 100% Profit Boost Token, valid only for a NCAA Tournament Winner bet. Max. Bet: $10. Profit Boost Tokens are single-use and expire on 4/6/26 at 11:59 PM ET. Must select Token BEFORE placing bet. Boost only applies to winnings. Ends 4/6/26 11:59 PM ET. Terms: Promos | DraftKings Sportsbook

While we know Tyler Glasnow will take the hill for the Dodgers, it's yet to be determined who will get the start for Milwaukee tonight. Glasnow has been lights-out in the postseason, holding the Phillies to a .154 batting average across 7.2 shutout innings in two appearances. After a relief appearance in NLDS Game 1, Glasnow delivered six innings of two-hit shutout baseball to help lift the Dodgers to a series-clinching win. In fact, Glasnow hasn't allowed a single run in 15 innings, dating back to the first inning of his Sept. 20th start against the Giants.

Dodgers manager Dave Roberts is fully confident Glasnow will get the job done in Game 3 after Blake Snell and Yoshinobu Yamamoto's masterclass performances in Games 1 and 2.

“As far back as time … starters sort of want to feed off each other, compete against one another, push each other,” Roberts said. “And that's what we're sensing from our staff. It's going to be hard to top Blake and what Yoshinobu did, but I'm sure Glas is going to try to put his mark on this [series].”

There's a pretty good chance Glasnow will completely dominate the Brew Crew, as he has allowed just 10 hits in 71 career at-bats against Brewers hitters (.141 batting average). Christian Yelich has especially struggled to compete against the former Tampa Bay Rays standout, going a career 1-for-14 with 7 strikeouts so far.

Jacob Misiorowski is expected to either get the start or throw 3-5 innings of baseball in relief tonight. Milwaukee will likely use its whole roster of pitchers to take full advantage of pitching matchups throughout the ballgame. Will it work? We're not sure, but it's the only plan that they've got. It should work to some degree, and I fully expect this game to go under the 7.5 run total.

The Brewers only have five hits so far this series, and the outlook isn't any better tonight. If they're to win, they'll have to keep the Dodgers off the scoreboard and win a low-scoring game. If you believe in the Brewers, parlay the Brewers ML with the under (+425 on BetMGM Sportsbook).

Featured Image Mandatory Credit: John Froschauer-Imagn Images