March Madness Odds: Sweet 16 Spreads, Totals, And Moneylines For Every Game

Written By Staff on March 25, 2019 - Last Updated on April 29, 2021

Well, that was a quick week.

The field of 68 in the NCAA Tournament has already been trimmed down to 16 following the first week of March Madness. Now, the stakes increase even more. Only four wins stand between one remaining team and the title.

The Round of 16 will take place on Thursday, March 28, and Friday, March 29, followed by the Elite 8 on Saturday and Sunday. Final 4 weekend tips off Saturday, April 6 in Minneapolis.

Below are the betting lines for the Sweet 16 matchups at DraftKings Sportsbook, along with futures odds for remaining 16 teams at DraftKings, FanDuel Sportsbook and FOX Bet in New Jersey.

NCAA Tournament Sweet 16 Odds

GameRegionSpreadTotalMoneyline
#1 Duke vs #4 Virginia TechEastDuke -7144.5Duke -335
Virginia Tech +265
#2 Michigan St. vs #3 LSUEastMSU -6149MSU -265
LSU +215
#1 Gonzaga vs. #4 FSUWestGonzaga -7.5146.5Gonzaga -345
FSU +275
#2 Michigan vs. #3 Texas TechWestMichigan -1.5126.5Michigan -124
Texas Tech +105
#1 Virginia vs. #12 OregonSouthVirginia -8.5118.5Virginia -455
Oregon +360
#2 Tennessee vs. #3 PurdueSouthTennessee -1.5146.5Tennessee -120
Purdue +100
#1 UNC vs. #5 AuburnMidwestUNC -5163.5UNC -220
Auburn +180
#2 Kentucky vs. #3 HoustonMidwestKentucky -2.5134.5Kentucky -148
Houston +123

March Madness Futures Odds

NCAA Winner

Game
(Eastern Time)
(EST)
Gonzaga
Bet now
+800
Bet now
+900
Baylor
Bet now
+800
Bet now
+1600
Virginia
Bet now
+900
Bet now
+900
Creighton
Bet now
+1100
Bet now
+2000
Kentucky
Bet now
+1200
Bet now
+1100
Duke
Bet now
+1400
Bet now
+1300
Villanova
Bet now
+1400
Bet now
+2500
Florida State
Bet now
+1500
Bet now
+2000
Iowa
Bet now
+1500
Bet now
+5000
Wisconsin
Bet now
+1600
Bet now
+2500
San Diego State
Bet now
+1600
Bet now
+2500
Kansas
Bet now
+1700
Bet now
+1000
West Virginia
Bet now
+1900
Bet now
+3000
Oregon
Bet now
+2000
Bet now
+2800
Ohio State
Bet now
+2300
Bet now
+2800
Michigan State
Bet now
+2500
Bet now
+1000
Houston
Bet now
+3000
Bet now
+3500
Louisville
Bet now
+3000
Bet now
+2200
Texas Tech
Bet now
+3000
Bet now
+2200
Michigan
Bet now
+3500
Bet now
+2800

How to watch the NCAA Tournament Sweet 16

Thursday, March 28

(1) Gonzaga vs. (4) Florida State  | 7:09 p.m. ET (CBS)
(2) Tennessee vs. (3) Purdue | 7:29 p.m. ET (TBS)
(2) Michigan vs. (3) Texas Tech | Approx. 9:39 p.m. ET (CBS)
(1) Virginia vs. (12) Oregon | Approx. 9:59 p.m. ET (TBS)

Friday, March 29

(2) Michigan State vs. (3) LSU | 7:09 p.m. ET (CBS)
(1) North Carolina vs. (5) Auburn | 7:29 p.m. ET (TBS)
(1) Duke vs. (4) Virginia Tech | Approx. 9:39 p.m. ET (CBS)
(2) Kentucky vs. (3) Houston | Approx. 9:59 p.m. ET (TBS)

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