March Madness Betting Guide: Duke Blue Devils vs. Houston Sweet 16 Odds

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Written By Eli Hershkovich | Last Updated
Duke Odds

With March Madness odds resuming later in the week, South Region odds deliver one of the most intriguing Sweet 16 matchups. The top-seeded Houston Cougars battle the fourth-seeded Duke Blue Devils for the right to advance to the Elite Eight. Let’s handicap Duke odds vs. Houston. Tar Heel Blue Devil State residents can also receive the best NC sportsbook promos. These exclusive offers will net you up to $2,700 in bonus bets!

Click on anywhere below to wager on Houston or Duke. These odds are the best available in your state.

Duke odDs vs. Houston: spread, moneyline, total

Per the table above, the best Duke spread odds are . Conversely, the Cougars are just to win straight up. The total is lined at . Remember that NC residents can receive exclusive offers on NC sports betting apps.

Blue Devils To Continue Hot Shooting?

Duke wasted no time disposing of upset-minded James Madison in the second round of the NCAA tournament. The Blue Devils jumped out to a 24-9 lead thanks to five-star freshman Jared McCain hitting four 3-pointers. He wound up doubling that total in the 38-point romp.

Jon Scheyer’s team is no slouch regarding its perimeter efficiency, boasting a top-15 clip (38.1%) across Division I. However, those looks won’t be nearly as attainable against Houston’s top-rated defense. While the Cougars go for their fair share of swipes, it doesn’t affect their coverage around the arc, limiting opponents to a 30.3% clip.

Jamal Shead, a first-team All-American, and Emmanuel Sharpe are two of the premier ballhawks in the country. That isn’t even accounting for LJ Cryer’s defensive growth after transferring in from Baylor in the offseason.

Moreover, they rank No. 97 in opponents’ open 3-point attempt rate. Assuming J’Wan Roberts & Co. sustain their dominance on the glass, Duke won’t manufacture many fast-break looks from beyond the arc.

At the other end, the Blue Devils’ transition defense is a sizeable liability. The surface-level numbers may suggest otherwise, but when you factor in their outings against upper-echelon competition (Arizona, North Carolina, Baylor, Clemson, N.C. State, Pitt), they ranked bottom 10 percentile nationally. That is a death sentence against Houston — especially if it’s turning Duke over.

Predictions For Duke Odds

My raw numbers favor Houston by roughly six points. On the flip side, our partner Haslametrics projects a 69.6-66.1 win for the Cougars, aligning slightly with Duke’s spread odds. Catch my Sweet 16 betting podcast with Erik Haslem, the founder of Haslametrics, below!

Sweet 16 Player Props

More Duke Betting Odds

More Houston Betting Odds

You can subscribe to the audio-only version of the show on Apple, Spotify, or wherever you find your favorite podcasts.

are there North Carolina sports betting restrictions For March Madness?

Bettors in North Carolina must be 21 or older. Sportsbook customers can bet on in-state college teams without stipulations on individual prop bets, including UNC, Duke, and NC State player props in the 2024 NCAA Tournament.

Overall, North Carolina sports betting is not restrictive. Sportsbook users can wager on professional and collegiate sports at their leisure.

Local college teams, including North Carolina, Duke, and NC State in the NCAA tournament, are always offered.

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