Duke vs. James Madison Second-Round Odds: March Madness Betting Guide

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Written By Eli Hershkovich | Last Updated March 24, 2024

With second-round March Madness odds continue in the South Region on Sunday. The fourth-seeded Duke Blue Devils take on the 12th-seeded James Madison Dukes, with a trip to the Sweet 16 on the line. Blue Devil State residents looking to bet Duke odds can also register for NC sportsbook promos. These exclusive offers will get you up to $2,950 in bonus bets!

Click on any odds below to bet on Duke or James Madison. The second-round odds are the best available in your state.

duke vs. james madison: spread, moneyline, total

Per the betting table above, the best Duke odds are . Meanwhile, James Madison is to deliver the straight-up upset. The total sits at . Remember that NC residents can receive exclusive offers on NC sports betting apps.

Moreover, NC BetMGM users will receive three 32% boosts (odds boost, live boost, and profit boost) to wager with throughout the second round!

JMU’s Ball Pressure To Continue Wrecking Havoc?

Although many bettors cheered on the Dukes during Friday’s upset win — the second-biggest one of the tournament at +600 moneyline odds — I teared up my Wisconsin Badgers futures ticket. James Madison turned over Greg Gard’s team 19 times, resulting in 27 points off takeaways, ultimately the difference in the game.

That was equivalent to Wisconsin’s highest turnover rate since the 2019 Big Ten Tournament. While the Blue Devils are giving the ball away at a top-50 rate, their turnover percentage — especially Tyrese Proctor’s — has increased slightly since non-conference play.

James Madison’s opponents evidently struggle to simulate its pressure defense. Duke could be its next victim if John Scheyer’s group fails to operate its motion and pick-and-roll attack efficiently.

Should that possibility come to fruition, the Blue Devils’ transition defense is another factor worth surveilling. Overall, their numbers in that department rank above the D-I average. Nevertheless, it’s stationed in the 41st percentile (via CBB Analytics) against more arduous teams, including the likes of UNC, Baylor, Wake Forest, NC State, and (early-season) Arkansas.

Predictions For Duke Odds

If you can jump on Dukes at +7.5 or better, our partner Haslametrics favors that side of the spread. Specifically, Haslametrics projects a 77.8-71.3 win for the Blue Devils. My raw numbers have it closer to Duke -8.

are there North Carolina sports betting restrictions For March Madness?

Bettors in North Carolina must be 21 or older. Sportsbook customers can bet on in-state college teams without stipulations on individual prop bets, including UNC, Duke, and NC State player props in the 2024 NCAA Tournament.

Overall, North Carolina isn’t a very restrictive state regarding sports betting. Sportsbook customers can wager on professional and college sports at their leisure. Betting offerings include in-state college teams, including North Carolina Tar Heels, Duke Blue Devils, and NC State in March Madness.