College Football Week 7 Odds & Cheat Sheet: Schedule, Injuries, Weather, Betting Notes

Buckle up, folks. Week 7 of the college football season offers the most dense slate, not just of the season but, of the last couple years. One of the sport's best and most unpredictable rivalries, the Red River Rivalry between No. 1 Texas and No. 18 Oklahoma, squares up at the Texas State Fair. The No. 2 Ohio State Buckeyes visit the No. 3 Oregon Ducks in what's now a pivotal Big Ten matchup. No. 9 Ole Miss takes on No. 13 LSU in a game with a track record of shootouts. And that's just scratching the surface of what college football odds boards offer in Week 7.

A buck wild Week 6 set the table and made things even more interesting. No. 7 Alabama looks to bounce back against a feisty South Carolina team after a shocking upset at Vanderbilt. No. 4 Penn State visits USC in a rematch of a classic Rose Bowl (2017). Other matchups of note include Stanford at No. 11 Notre Dame, Washington at Iowa, and No. 18 Kansas State at Colorado. Tuesday and Wednesday football returns, too.

Included are the latest odds, notable line movement, matchup history, weather, injuries, trends, and much more. Dig in! Keep up with TheLines all week long for college football betting tools.

College Football Week 7 Odds

Browse college football Week 7 odds below. Click odds anywhere to place a bet.

Line Movement: College Football Week 7 Odds

Look-ahead lines for Week 7 were posted last week. Check out early movers from those and the opening lines below:

• Washington opened a +4 underdog on the road at Iowa but re-opened on the key +3. FanDuel Sportsbook even offered a juiced -2.5 on Iowa as of Monday morning
• Over the summer, Texas opened -8.5 on a Game of the Year line. At re-open last week (both teams were on bye in Week 6), the Longhorns were -14.5 favorites
• Following a win at North Carolina, Pitt moved from -2.5 to as high as -4 against Cal
• Virginia, now 4-1, moved from a +8 underdog against Louisville to +7 at some books by Monday morning
• Two straight losses for UCF moved its line against Cincinnati from -7.5 to -3.5
• BYU jumped from a +1 home underdog to a -4 favorite against Arizona
• Tennessee moved from a -11 home favorite this summer to -15.5 vs. Florida
• Ohio State moved from a +1 road underdog this summer to now a -4.5 favorite at Oregon
• Ole Miss opened a +2.5 road underdog on a Game of the Year line to a -3 favorite at LSU
• West Virginia fell from a +3.5 home underdog to +3 at re-open
• Colorado moved from a +6 home underdog on Game of the Year lines to as low as +4.5 on Monday morning

Opening Lines from College Football Week 7 Odds

• Memphis jumped from a -5 road favorite at open to -6.5 by Monday morning
• Arizona State fell from a +5 home underdog at open to +3.5. Questions still surround Cameron Rising's availability coming off a bye
• Kent State moved from a +7 home 'dog to +6.5 by Monday morning. Watch for this one to potentially rebound, as Kent State is 0-5 ATS this year
• Georgia Tech took early action, moving from -4 at North Carolina to as high as -6
• Army continues to be bet, moving from -18.5 to -24.5 against UAB
• Eastern Michigan, a market favorite early this year, moved through a key figure vs. Miami (OH), from +3.5 to +2.5
• Northern Illinois moved from a +5 'dog at open to +3 by Monday morning at Bowling Green
• Akron fell from +12.5 to as low as +8.5 at Western Michigan
• Illinois rose from a -17.5 favorite to -19.5 vs. Purdue shortly after open
• New Mexico opened a -1.5 home favorite vs. Air Force and moved to -6.5. Air Force is struggling with injuries and underperformance this year
• Washington State moved through a key figure, jumping from a -2.5 road favorite to -3.5 at Fresno State
• Texas State jumped from a -11 favorite to -14 at home vs. Arkansas State
• Louisiana rose quickly from a -6 favorite vs. Appalachian State to -10.5 in the first 24 hours of the line posted
• Nevada, another team the market favored, fell from a +8.5 home 'dog to +3.5 in some spots against Oregon State
• Kentucky moved from -10.5 at open to -13.5 vs. Vanderbilt

Note line movements through key figures of 3 and 7, like Cal at Pitt and Washington State at Fresno State

Totals Movement

• Tuesday's Coastal Carolina at James Madison was bet up from 58.5 at open to as high as 62.5
• Toledo at Buffalo fell from 46.5 points at open to 44 by Monday morning
• Washington at Iowa rose from 39 at open to 41
• Louisville at Virginia fell from 57.5 points to 54.5
• Syracuse at NC State dropped from 56.5 points at open to as low as 54.5 points by Monday morning

Midweek College Football Week 7 Odds Rundown

• Liberty's Week 5 game at Appalachian State was canceled due to flooding from Hurricane Helene. The Flames last played on Sept. 21, where they beat East Carolina 35-24 (-7.5)
• New Mexico State, Middle Tennessee, and UTEP are a combined 3-12 ATS
• Jacksonville State played at Kennesaw State on Friday, just five days before they play vs. New Mexico State. The Aggies come off a bye
• Louisiana Tech is just 5-12 ATS against Conference USA foes the last two-plus years. Cumbie is 7-14 ATS against conference opponents in his coaching career

Coaching & Matchup Notes for College Football Week 7 odds

Memphis at USF, Friday (7:00 p.m., ESPN)

• Memphis leads the all-time series, 8-4
• Last year, these two teams combined for 109 points. Memphis won the contest, 59-50
• Both Memphis and USF come off a bye week. USF lost its previous game to Tulane, 45-10, while Memphis beat MTSU, 24-7
• USF QB Byrum Brown suffered an injury in the fourth quarter in Week 4 vs. Miami (FL) and followed it up with a season-worst 134 yards passing, 16 yards rushing performance at Tulane
• Watch for remnant impacts of Hurricane Milton to last throughout the weekend. Also, keep an eye on disruptions to the week as the major hurricane is expected to make landfall in Tampa. Most concerns would be lingering floods (the game could be axed) and residual wind

No. 21 Missouri at UMass, Saturday (12:00 p.m., ESPN2)

• First-ever matchup, Missouri hosts the rubber match of this home-and-home next year
• Missouri continues its bizarre run of visiting Group of Five opponents. Its last case came in 2019 (at Wyoming, a 37-31 loss). The Tigers are scheduled to visit San Diego State twice in 2027 and 2033, NIU in 2029, North Texas in 2030, and FAU in 2031. Mizzou was initially scheduled to visit Miami (OH) next season, but they backed out.
• Tigers are just 1-5 ATS as a double-digit road favorite since 2019
• UMass is 2-3-1 ATS this year, failing to cover the closing number by 7.4 points. The Minutemen needed a fourth-quarter touchdown to fend off Central Connecticut (230th-ranked D-I program) as -19.5 favorites

South Carolina at No. 7 Alabama, Saturday (12:00 p.m., ABC)

• Alabama leads the all-time series, 11-4. However, this is just the second meeting since 2010
• Kalen DeBoer is 23-2 at home as an FBS head coach
• Crimson Tide is 20-0 in the regular season against teams from the SEC East (now, teams formerly of), including its 41-34 win over Georgia this season (14-6 ATS)
• Shane Beamer holds a 3-10 record against ranked opponents at South Carolina
• However, South Carolina is 4-1 ATS against its last five top-10 opponents under Beamer (last: 24-14 loss to No. 1 Georgia last year as +27 'dogs)
• The Crimson Tide have surrendered 67 points in their last six quarters

Cincinnati at UCF, Saturday (3:30 p.m., ESPN2)

• UCF leads all-time series 5-4 in this former-AAC rivalry imported to the Big 12
• The last two meetings were separated by six combined points (UCF won both)
• Cincinnati comes off a bye, UCF's second straight opponent, with a rest advantage (fell to Florida, 24-13, last week)
• Gus Malzahn is 18-5 straight up at home with UCF and 68-17 at home in his career
• RB Corey Kiner left the Bearcats' Week 5 loss at Texas Tech after just six snaps. Kiner leads UC with 407 yards on 67 rushes
• Watch for remnant impacts of Hurricane Milton to last throughout the weekend. Also, keep an eye on disruptions to the week as the major hurricane is expected to make landfall in Tampa and have significant impacts on Orlando

Cal at No. 22 Pitt, Saturday (3:30 p.m., ESPN)

• Pitt leads the all-time series, 3-2, but has not played since 1966
• Pitt is off to a 5-0 start for the first time since 1991 (also 5-0 ATS!)
• All three road games for Cal so far this season exceeded 2,000 miles (Auburn, Florida State, Pitt)
• Golden Bears blew a 25-point lead in the second half last week and lost to Miami (FL), 39-38, with College GameDay making its first-ever appearance at Cal

No. 4 Penn State at USC, Saturday (3:30 p.m., CBS)

• USC leads the all-time series, 6-4, with the last on-campus meeting coming in 1994
• Rematch of the 2017 classic Rose Bowl, where Sam Darnold led USC to a 17-0 fourth-quarter edge, beating Penn State 52-49
• Lincoln Riley is 2-6 ATS, coming off a straight-up loss at USC (5-9 in his career). The Trojans lost to Minnesota, 24-17, last week
• First regular season game outside the Eastern or Central Time Zone for Penn State since 2014 (in Dublin, Ireland). First regular season game outside ET/CT since 1992 (at BYU)
• Watch for unseasonably hot temperatures in L.A. this weekend, with October highs near 90º

Stanford at No. 11 Notre Dame, Saturday (3:30 p.m., NBC)

• Teams play for the Legends Trophy, established in 1989 when rivalry began its annual meeting
• Notre Dame leads the all-time series, 22-14
• Stanford upset Notre Dame last time in South Bend, 16-14, as +16 underdogs (the road team is on a 4-0 SU run)
• Stanford has played on the road in three of its last four games, traveling over 2,000 miles each way each time (over 15,000 miles total!)
• Notre Dame comes off a bye, while Stanford comes off a 31-7 loss to Virginia Tech
• QB Ashton Daniels missed the Cardinal's Week 6 loss to Virginia Tech

No. 1 Texas vs. No. 18 Oklahoma, Saturday (3:30 p.m., ABC)

• Red River Rivalry (formerly Red River Shootout), teams play for the Golden Hat
• Played at the Cotton Bowl in Dallas at the center of the Texas State Fair. Each matchup since 1932 has been played here
• Texas leads the all-time series, 63-51-5, but Oklahoma has won seven of the last nine
• As is tradition, both teams rest on bye heading into the matchup
• Nine of the last 11 meetings have been decided by eight or fewer points. Exceptions were Texas' 49-0 dominant win in 2022 and Oklahoma's 39-27 win in the 2018 Big 12 Championship
• QB Quinn Ewers is expected to return after missing Texas' last two games
• Oklahoma was without its top five receivers in a 27-21 win at Auburn in Week 5
• This line opened as a Game of the Year in the summer, favoring Texas by 8.5 points

Arizona at No. 14 BYU, Saturday (4:00 p.m., FOX)

• The all-time series is tied 12-12-1
• BYU won each of the last three meetings (2021, 2018, 2016)
• Arizona changed its offensive play-caller, from OC Dino Babers to TEs coach Matt Akins
• BYU comes off a bye week (5-0 ATS), while Arizona (-6) comes off a 28-22 loss to Texas Tech
• NCAA has not come down with a ruling on RB Jacory Croskey-Merritt, who has not played since Week 1 due to eligibility concerns

Florida at No. 8 Tennessee, Saturday (7:00 p.m., ESPN)

• Florida leads the all-time series, 32-21, and has won six of the last seven and 17-of-19
• Josh Huepel is 14-5 ATS as a home favorite at Tennessee
• When held under 30 points, Huepel is now 1-13 outright at Tennessee, including last week's 19-14 loss at Arkansas (-14 favorites)
• Last year, Florida (+5) upset Tennessee, 29-16, in Gainesville
• Note spot for both teams: Vols coming off big upset loss, Florida comes in after upset win vs. UCF

No. 2 Ohio State at No. 3 Oregon, Saturday (7:30 p.m., NBC)

• Ohio State leads the all-time series, 9-1, but Oregon won the last meeting (2021 in Columbus)
• First time this game has been held in Eugene since 1967 and only the second time ever (six times in Columbus, three neutral)
• Based in the Pac-12, but Oregon is 10-4 straight up and ATS against top-10 conference opponents at home
• The market has bet against the Buckeyes in all five games this year

Check out the full rundown of Ohio State at Oregon odds here

No. 9 Ole Miss at No. 13 LSU, Saturday (7:30 p.m., ABC)

• LSU leads all-time series, 65-42-4
• Since 2016, these two teams combined for an average of 74.6 points (78.4 removing a 31-17 decision in 2021)
• Last year, LSU and Ole Miss combined for 104 points in a wild 55-49 Rebels home win
• Fourth quarters averaged 19 points in these games, 20.3 removed the lowest-scoring game (2021)
• Ole Miss rebounded from the loss to Kentucky (-15 favorites) in a 27-3 win at South Carolina (-9.5 favorites)
• LSU comes off a bye

No. 18 Kansas State at Colorado, Saturday (10:15 p.m., ESPN)

• Colorado leads the all-time series, 45-20-1
• Chris Klieman is 32-17 ATS against conference foes at Kansas State (.653)
• K-State is 0-4 ATS coming off a bye since 2020 (outright loss as -11 favorite in '23, underdogs each of the other times)
• Deion Sanders is 3-0 ATS as a home underdog at Colorado (first instance this year)
• Both teams come off a bye

Impact Injuries On College Football Week 7 Odds

All kick times below are listed in ET.

Northwestern at Maryland, Friday (8:00 p.m., FOX)

Northwestern has been without a couple of projected starters along the offensive line this season. Tackle Matt Keeler and guard Jordan Knox have yet to play a snap this season. Workhorse running back Cam Porter missed Week 5 and played just six snaps in Week 6. Northwestern lost both games, scoring just five points without him at Washington. Starting defensive tackle Carmine Bastone has also yet to play a snap this year.

Stanford at No. 11 Notre Dame, Saturday (3:30 p.m., NBC)

The injuries continue to pile up for Notre Dame. Already down four starters for the entire season, rotational defensive lineman Boubacar Traore will miss the rest of the season with a knee injury. Corner Jaden Mickey, defensive end Jordan Bothelo, center Ashton Craig, and tackle Charles Jagusah are all done for the year. Receiver Jordan Faison and defensive end Josh Burnham have both missed multiple games, including Week 5. Starting guard Billy Schrauth left Week 3 on a cart but should return soon, if not this week.

Northern Illinois at Bowling Green, Saturday (3:30 p.m., ESPN+)

NIU was down its two best offensive players last week in RB Antario Brown and WR Trayvon Rudolph. Brown, a versatile dual-threat back, has over 600 scrimmage yards and three touchdowns on the year. In the passing game, he averages 25.5 yards per reception (only 1.3 aDOT!) and peaked with 126 receiving yards in NIU's massive upset win at Notre Dame. Rudolph has just 119 yards receiving but plays an important role in the return game.

No. 1 Texas vs. No. 18 Oklahoma, Saturday (3:30 p.m., ABC)

Oklahoma was without its top five receivers–Nic Anderson, Andrea Anthony, Deion Burks, Jalil Farooq, and Jayden Gibson–in a Week 5 win at Auburn. Running back Taylor Tatum, who is emerging as a top offensive player, and starting linebacker Dasan McCullough also missed the contest. QB Michael Hawkins received his first start of the year in Auburn, passing for 161 yards and rushing for 76 more. Oklahoma ranks just 88th in points per drive.

On the other side, Quinn Ewers is expected to return after missing two games. Arch Manning played in replacement duty, throwing four touchdowns and two interceptions, plus rushing for another.

Air Force at New Mexico, Saturday (7:00 p.m., truTV)

Air Force has been extremely banged up this year. In a 31-7 loss to Navy last week, fourth-leading rusher Aiden Calvert and starting fullback Terrence Gist missed alongside three defensive starters. The Falcons are 0-5 ATS this season against FBS foes, coming up two touchdowns short of the closing number, on average. Air Force ranks dead last in offensive points per drive (0.88).

No. 9 Ole Miss at No. 13 LSU, Saturday (7:30 p.m., ABC)

Ole Miss is down some key pieces. Heading into Week 6, Tre Harris led the nation with over 800 receiving yards. He was limited to 34 snaps in Week 6 and saw just four targets (prior low: 9 in Week 1). Princely Umanmielen, who has four sacks and 20 total pressures on the year, did not play in the 27-3 win at South Carolina. Starting guard Jeremy James has been out since Week 1 with a broken hand and does not have an updated timeline for a return.

LSU lost star linebacker Harold Perkins for the season due to a torn ACL suffered in Week 4. Starting defensive tackle Jacobian Guillory and running back John Emery are also out for the year with a torn Achilles and ACL, respectively. Receiver Chris Hilton has not yet played this year and corner Zy Alexander–who has struggled with injuries his entire career–sat out Week 5.

Syracuse at NC State, Saturday (8:00 p.m., ACC Network)

NC State QB Grayson McCall suffered a scary injury last week against Wake Forest and was admitted to the hospital. The Coastal Carolina transfer is in concussion protocol and will not play this week. McCall was out of the lineup for Weeks 4 and 5 for a separate injury and has struggled this season. Safety Devan Boykin missed all of September and is hopeful to return at some point this month. Last year's leading sack-getter, DE Red Hibbler, opted to redshirt and transfer after the season.

Syracuse is down a pair of receivers – Justus Ross-Simmons only played 15 total snaps before this week, and Zeed Haynes has not played since Week 2.

Other Impact Injuries

• Cameron Rising, QB, Utah (GTD)
• Roger Carreon, RG, Boise State
• Terion Stewart, RB, Bowling Green
• Peter Woods, DL, Clemson
• Eugene Wilson III, WR, Florida
• D.J. Uiagalelei, QB, Florida State
• Mykel Williams, DE, Georgia
• Ayo Adeyi, RB, James Madison
• Maurice Turner, RB, Louisville
• Jace Henry, TE, Nevada
• Tyliek Williams, DT, Ohio State
• Jason Henderson, LB, Old Dominion
• Rocket Sanders, RB, South Carolina
• Bru McCoy, WR, Tennessee
• Squirrel White, WR, Tennessee
• Ben Bell, DE, Texas State
• Andre Fuller, CB, Toledo
• Luke Pawlak, K, Toledo
• Jacob Zeno, QB, UAB
• Ethan Garbers, QB, UCLA
• Eric Gentry, LB, USC
• Byrum Brown, QB, USF
• Jalen Buckley, RB, Western Michigan
• Kevin Pointer, DL, Wake Forest
• Mason Randolph, C, Boise State (season)
• Andrew Glass, K, Kent State (redshirt)
• Colton Boomer, K, UCF (redshirt)
• Xavier Townsend, WR, UCF (redshirt)
• Rashad Cheney Jr., DL, USF (season)
• Sage Ennis, TE, Nevada (season)
• Chez Mellusi, RB, Wisconsin (season)

Other Roster & Staff Impacts on College Football Week 7 Odds

Arizona at No. 14 BYU, Saturday (4:00 p.m., FOX)

Following Arizona's Week 4 bye, offensive coordinator Dino Babers relinquished play-calling duties. Passing game coordinator/TEs coach Matt Adkins instead took the duties over, leading Arizona to a 23-10 upset of Utah in Week 5. The Wildcats gained 422 yards but turned the ball over three times in a 28-22 loss to Texas Tech last week. Atkins called more deep shots than Babers, increasing QB Noah Fifita's average depth of target (aDOT) from 5.2 and 8.9 in his previous two games to 11.4 and 10 in his next two.

Southern Miss at ULM, Saturday (5:00 p.m., ESPN+)

ULM made a change at quarterback, from Oklahoma transfer General Booty to backup Aidan Armenta. Booty had just one touchdown pass in four starts and none in three FBS games, completing just 52% of his passes. In his first start, Armenta threw a touchdown and an interception (17-of-30 passing) in a 21-19 upset over James Madison. ULM continues to be led by its defense.

For teams on bye:

• Michigan likely starts QB Jack Tuttle over either previous option. Tuttle returned from injury and replaced Alex Orji last week, throwing for 98 yards and a touchdown in a 27-17 loss at Washington.
• Katin Houser replaced Jake Garcia at QB for East Carolina last week. Garcia had eight touchdown passes but 12 interceptions and 16 turnover-worthy throws through six games before getting benched. Houser, a Michigan State transfer, completed just 11 of his 29 passes for 88 yards, no touchdowns, and a pick in an ugly 55-24 loss to Charlotte.

Weather Impacts On College Football Week 7 Odds

Weekly college football weather reports will be released later this week as forecasts become more certain. But here’s a few spots to keep tabs on early in the week.

Impending Hurricane Milton will not impact games directly this weekend as it makes landfall Wednesday PM. However, keep an eye on disruptions during the week for Memphis at USF (Friday) and lingering effects on the Tampa area. Milton is expected to make landfall as a major hurricane and is growing in intensity. Other potential areas impacted include Orlando, which includes Saturday's Cincinnati at UCF games.

We saw last week as Appalachian State dropped a game at Marshall (allowed 52 points) after a disrupted week due to catastrophic flooding from Hurricane Helene. Worst case, Memphis at USF is cancelled like Liberty at Appalachian State.

The rest of the country should enjoy gorgeous, if not unseasonably warm, and calm weather.

Situational Spots To Watch With College Football Week 7 Odds

Northwestern at Maryland, Friday (8:00 p.m., FOX)

Mike Locksley has a poor track record coming off bye weeks in his career. Coming into this season, Maryland is 3-7 off a bye week outright, losing last year at Northwestern as -14 favorites. While opponent-dependent, poor play-off bye weeks suggest poor planning and management of the rest. UMD was an underdog in many of the games they rested before, but rarely a large underdog. Other opponents included UCF (-4, 2017), Indiana (+1, 2020), and Wisconsin (+5, 2022).

Washington at Iowa, Saturday (12:00 p.m., FOX)

Washington pulled off a 27-17 upset at home over No. 10 Michigan last week. Now, the Huskies hit the road for Iowa City–a notoriously difficult place to play–to face another extremely physical team in Iowa. The Hawkeyes field one of the best running backs in the country, Kaleb Johnson, who managed to rush for 86 yards and Iowa's only touchdown on Ohio State last week. Outside of that game, Johnson averages 188.7 yards against FBS competition. Washington allowed 174 yards on the ground with no threat of a passing game last week against Michigan.

Miami (OH) at Eastern Michigan, Saturday (2:00 p.m., ESPN+)

Miami plays its third road game in four weeks, concluding this week. The Redhawks also play a second straight road opponent with a rest advantage. Last week, Miami (+6.5) fell to Toledo, 30-20. Eastern Michigan beat Miami in each of the last two meetings (2021, 2017) as +2 underdogs each time.

Stanford at No. 11 Notre Dame, Saturday (3:30 p.m., NBC)

Stanford hit the road for three of its last four games, all of which come in the Eastern Time Zone. The Cardinal travel over 15,000 total miles for the games and are 1-2 outright (1-2 ATS) so far. Notre Dame is also the second of five opponents in a seven-game stretch coming off a bye for Stanford. The Cardinal return home to play SMU (coming off a bye) next week.

Akron at Western Michigan, Saturday (3:30 p.m., ESPN+)

Akron concludes an arduous stretch of games this weekend. Five of its first seven games came on the road – without a bye week to rest. Last week, the Zips (+16.5) fought to a 27-20 loss at home against Bowling Green to fall to 0-5 against FBS competition. Western Michigan returned WR Kane Womack to the lineup two weeks ago and looks to get RB Jalen Buckley back soon. WMU scored a season-best 45 points vs. FBS teams in overtime last week against Ball State.

Florida at No. 8 Tennessee, Saturday (7:00 p.m., ESPN)

Florida comes off an emotional home win against UCF in which Billy Napier likely bought extra time on his job with the Gators. Tennessee returns home after a shocking loss to Arkansas in Fayetteville. Expect opposite motivations here, with the Vols looking for an emphatic bounce back against an opponent that's won 17 of the last 19 meetings. Florida, on the other hand, sits in a prime letdown spot after beating a key in-state rival.

Washington State at Fresno State, Saturday (7:00 p.m., FS1)

Jake Dickert is 0-5 straight up off a bye week at Washington State. Wazzu was a one-score underdog in three of those five games and a -7 favorite at Cal in 2019. This week, the Cougars are -3.5 road favorites at Fresno State and come off a loss at Boise State in front of a record crowd. Fresno State comes off a 59-14 loss to UNLV in Week 5.

Air Force at New Mexico, Saturday (7:00 p.m., truTV)

As an FBS head coach, Bronco Mendenhall is 78-36 ATS as a home favorite (.684, no such instances this year). New Mexico opened as a -1.5 favorite over Air Force in Albuquerque and grew to -6.5 as of Monday afternoon. Air Force is one of five winless FBS teams ATS this season, coming up two full touchdowns short of the closing number, on average. New Mexico has a rest advantage, both coming off a bye and playing at home.

No. 9 Ole Miss at No. 13 LSU, Saturday (7:30 p.m., ABC)

Ole Miss plays its second consecutive road game against an opponent with a rest advantage this week. Since 2016, these two teams combined for 74.6 points per game, 78.4, when removing the lowest scoring output (48 points, 2021). Given the propensity to score in buckets and with multiple games at a rest disadvantage, Ole Miss finds itself in a difficult spot.

Vanderbilt at Kentucky, Saturday (7:45 p.m., SEC Network)

Is there a more prolific letdown spot than what Vanderbilt faces this week? The Commodores shocked the college football world, pulling off a 40-35 upset of No. 1 Alabama in Nashville. Vanderbilt fans marched the goalposts down to the Cumberland River and dumped them in there as Tennessee did to Alabama in 2022. Now, the 'Dores head to Lexington to play an extremely physical Kentucky team with one of the country's best defensive lines. The Wildcats come off a bye.

Marshall at Georgia Southern, Saturday (8:00 p.m., ESPNU)

Week 7 indicates the fourth consecutive opponent coming off a bye and the third straight with a rest advantage that Marshall has played. The Thundering Herd are 1-2 ATS in the past three, covering the number against Appalachian State–who dealt with disruptions to the week due to catastrophic flooding–52-37 (-3).

Minnesota at UCLA, Saturday (9:00 p.m., Big Ten Network)

Minnesota pulled off an unlikely 24-17 win at home against No. 11 USC last week. However, the Gophers were significantly out-played in multiple facets, including on third down (gave up 7-of-11, converted 2-of-8). According to Dr. Parker Fleming (@statsowar on Twitter), no team won with a worse net success rate than Minnesota last week. UCLA sits 1-4 on the season (0-3 Big Ten) and is one of the lowest-ranked Power teams this season. This has the potential for a real letdown for the Gophers, who have to travel cross-country for the first time since 1997.

Best of luck betting college football Week 7 odds!