College Football Week 5 Odds: Two Top-10 Matchups Highlight Packed Week

Written By Brett Gibbons on October 1, 2021
College Football Week 5 odds

College Football Week 5 might just be the most packed slate we have all season. Ranked showdowns between Cincinnati and Notre Dame, Arkansas and Georgia, and Ole Miss and Alabama. Conference play is in full swing and October is officially here. Defense highlights this week with games like Michigan at Wisconsin.

Get ready for fireworks. Now, let’s dive into the top college football matchups of Week 5.

College Football Week 5 Odds

College Football Week 5 Top Games

#7 Cincinnati at #9 Notre Dame ()

When the dust settles on this upcoming season, no one will be able to say Cincinnati is unproven. The Bearcats unsurprisingly sit top-20 in yards per play allowed, but have shown vulnerability defensively so far. They face their toughest test of the season against Notre Dame. The Irish are coming off a big win over ranked Wisconsin in Chicago.

Cincinnati’s defensive line is one of the better units in the country. They look to take advantage of a struggling Notre Dame group that was dominated early against Wisconsin. Coaching chops will be the x-factor in this game, though, as Notre Dame’s Brian Kelly adjusted accordingly to slam the door on the Badgers. Meanwhile, Luke Fickel is one of the nation’s hottest names for openings like USC.

Don’t expect a high-scoring game in this one (over/under ), though Cincinnati’s averaging the fifth-most points in the nation (43.5).

#8 Arkansas at #2 Georgia ()

Arkansas might just be the hottest team in the country with wins over ranked Texas and top-10 Texas A&M. Sam Pittman’s squad has played tough, physical defense while adding a top-10 rushing offense (5.6 team yards per attempt). Quarterback KJ Jefferson is also playing lights-out, but was banged up against Texas A&M last week.

They meet Georgia, who many are crowning the best team in the nation. The Bulldogs lead the country in opposing yards per play (just 3.1) and sit top-10 in the country in rushing defense (2.3 yards per rush). Georgia has a big win of their own, Week 1 where they beat Clemson, and put offensive worries to bed last week when they dropped 62 points.

College Gameday chose this one as their game of the week. It’s a brutal prove-it game for Arkansas, but the Razorbacks have a real chance to solidify themselves as national contenders Saturday in Athens.

#14 Michigan at Wisconsin ()

Week 4 didn’t go as planned for Wisconsin, who fell out of the AP Top 25 for the first time this season. Poor quarterback play from Graham Mertz propelled Notre Dame to a big 41-13 win over the Badgers. There’s no rest for Wisconsin, though, as they return home to face Michigan.

The Wolverines are coming off a 20-13 win over previously-unbeaten Rutgers to extend their record to 4-0. Michigan fields a physical team that’s built on running the ball. Their 16.2 pass attempts per game is lowest in the FBS besides the service academies (Army, Navy, Air Force).

This is a mano-a-mano matchup for old school football enthusiasts. The game carries a point total.

#12 Ole Miss at #1 Alabama ()

Are we serious with all of these ranked games? Ole Miss has climbed the rankings since debuting at #25 preseason behind their explosive offense. The Rebels lead the country in points per game (52– an increase of 12.8 points per game since last year) behind incredible play from Heisman hopeful Matt Corral.

However, they haven’t faced a team like Alabama yet. The Tide command the top spot in the AP Poll with just four votes going elsewhere for number one. Bryce Young leads the country in Heisman odds (). Two weeks ago, Florida was able to exploit the Alabama defense behind a strong running game and a mobile quarterback. Can Ole Miss do the same?

The point total for this game is expected to be lofty. Keep an eye on what’s released this week in response to these potent offenses.

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Brett Gibbons

Brett is an avid sports traveler and former Division-I football recruiter for Bowling Green and Texas State. He’s a graduate of BGSU and works as an auditor for Google content curation products. He’s also contributed to Sports Illustrated and Fansided during his young writing career.

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