College Football Week 13 Best Bets, Odds, Picks & Player Props

As the college football regular season hits Week 13, sportsbook promotions continue to bring value before conference championships arrive on the top sports betting apps. Today’s slate offers a strong mix of heavy favorites, live underdogs and a clean set of player props that shape some of the best college football bets today.

We’ve got five game lines we like, followed by individual player props and a three-leg parlay with appealing upside.

Game Lines

Syracuse +36.5 (-105) vs Notre Dame

🏈Odds via Caesars Sportsbook📈

Syracuse catching 36.5 gives enough room to stay within striking distance even if this turns lopsided early. Their defense has shown flashes and the number is large enough to create value.

Texas -8.5 (-110) vs Arkansas

🏈Odds via bet365📈

Texas laying 8.5 carries real potential given the Longhorns’ ability to win at the line of scrimmage. Arkansas struggles with consistency and matches up poorly against Texas’ balance.

Oregon -10.5 (-105) vs USC

🏈Odds via Caesars Sportsbook📈

Oregon’s offensive tempo and defensive pressure should give USC trouble. With the Ducks capable of explosive scoring waves, a double-digit spread is realistic.

Tulane -9.5 (-110) vs Temple

🏈Odds via bet365📈

Tulane’s physicality and defensive discipline make this a strong spot. Temple has difficulty sustaining drives and Tulane should be able to control the game throughout, especially with the CFP bid motivation.

BYU -2.5 (-120) vs Cincinnati

🏈Odds via BetMGM📈

BYU at -2.5 is a manageable number. The Cougars' defensive front and ability to win situational downs set them up well to cover against a Cincinnati team that struggles to generate explosive plays.

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Player Props

Carnell Tate Anytime TD Scorer (-176)

🏈Odds via BetMGM📈

Tate is one of Ohio State’s most explosive receivers and continues to earn high-value targets. With his red-zone usage and big-play ability, this is a strong anytime touchdown spot.

Isaiah Sategna Over 64.5 Receiving Yards (-115)

🏈Odds via bet365📈

Sategna has been the most reliable option for Oklahoma with the speed to win vertically and in space. Missouri’s secondary is vulnerable to chunk plays, making 64.5 a reachable number.

Taylen Green Over 51.5 Rushing Yards (-115)

🏈Odds via BetMGM📈

Green’s dual-threat profile is a problem for defenses. His designed runs and scrambling ability give him multiple avenues to clear 51.5 rushing yards against Texas given he'll likely be pressured all game, especially if this game stays competitive.

Conner Weigman Over 203.5 Passing Yards (-120)

🏈Odds via bet365📈

Weigman has settled in as Houston’s leader under center and should see solid volume against TCU. With his arm talent and the Cougars’ willingness to push the ball, 203.5 passing yards is very attainable.

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Today's Best Parlay

🏈Combined Parlay Odds: +215 (via BetMGM)📈

• Leg 1: Tennessee ML (-197)
• Leg 2: Jeremiah Smith Anytime TD Scorer (-225)
• Leg 3: Oklahoma ML (-225)

Tennessee holds matchup advantages across the board against Florida and should be able to dictate tempo and game flow. Their balance on both sides of the ball makes them a solid moneyline anchor. Smith is a true alpha receiver for Ohio State and a focal point in the red zone. His target share and usage give him multiple paths to finding the end zone. Oklahoma’s offensive pace and efficiency should put pressure on Missouri from the jump. The Sooners have the edge in depth and consistency, which sets them up well to close this out.

Pairing Smith’s scoring profile with the Oklahoma and Tennessee moneylines gives this parlay stability while still delivering upside at +215. It’s a balanced mix of talent, matchup edge, and consistency across all three legs, while the four standalone props provide additional ways to attack the Week 13 board.

As always, check sports betting apps for updated numbers and sportsbook promotions before locking anything in as you look for the best college football bets today.

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All Odds as of 6:00 a.m. ET on Nov. 22