College Football Week 10 Odds & Cheat Sheet: Schedule, Injuries, Weather, Betting Notes

A rather unremarkable Week 9 gives way to an intriguing Week 10 with plenty of College Football Playoff impact. The CFP conversation takes center stage moving forward as the regular season rounds third base. Top games this week include No. 4 Ohio State at No. 3 Penn State, Florida vs. No. 2 Georgia, and No. 18 Pitt at No. 20 SMU. Lots of teams rest on bye this week, but the smaller slate is dense with intrigue. This weekend, no games kick off later than 8 p.m. ET. Let's take a look at everything you need to know to bet college football Week 10 odds.

Included are the latest odds, notable line movement, matchup history, weather, injuries, trends, and much more. Dig in! Keep up with TheLines all week long for college football betting tools.

College Football Week 10 Odds

Browse college football Week 10 odds below. Click odds anywhere to place a bet.

Line Movement: College Football Week 10 Odds

Check out early movers from those and the opening lines below:

• This summer, Ohio State opened as a -3 favorite against Penn State, and that grew to -4 at the latest re-open
• Florida fell from a +22 underdog against rival Georgia to +16 at re-open Monday
• Iowa State climbed from a -11 favorite against Texas Tech to -14.5 by Monday morning
• This summer, Oregon opened as a -2.5 favorite at Michigan but re-opened at -14.5
• Clemson rose from a -9.5 favorite against Louisville to -11.5 on Monday morning
• Tennessee moved from a -13 favorite against Kentucky to -16

Opening Lines from College Football Week 10 Odds

• Virginia Tech blew through a key number, being bet up from -1 to -4 at Syracuse by Monday
• Arkansas took plenty of movement, bet down from +9.5 to +6.5 by Monday
• Action pushed Toledo through a key number, from -6 to -7.5, at Eastern Michigan
• Though going through zero represents a more negligible change in win rate, Minnesota flipped from a +2.5 underdog to -2.5 at Illinois
• UTSA fell from +10.5 to +7.5 against Memphis
• Despite its recent momentum, Vanderbilt fell from a +5 underdog at Auburn to +6.5
• Old Dominion flipped from a +2.5 underdog to -2.5 at Appalachian State
• UAB took plenty of movement, climbing from -1 to -3.5 at home against Tulsa
• UCF climbed from -4 at open to -6.5, approaching -7, against Arizona
• UTEP moved on to a key figure, from -2.5 to -3, against Middle Tennessee
• Rice fell from +14.5 against Navy to +12.5
• New Mexico climbed from -5.5 to -7 against Wyoming
• UMass fell from +22.5 at open to +18 at Mississippi State
• Washington fell off a key number, from +3 to +2.5, against USC
• Baylor moved first, from -2.5 to -3, against rival TCU
• SMU moved on to a key figure, from -6.5 to -7, against Pitt

Note line movements through key figures of 3 and 7, like Tulsa at UAB and Virginia Tech at Syracuse.

Totals Movement

• Virginia Tech at Syracuse bumped up from 52.5 to 53.5 early in the week
• Ole Miss at Arkansas crashed from 58 to 54.5 points, moving through 55 points
• Duke at Miami (FL) moved off key 55 to 54.5
• Minnesota at Illinois fell from 47 points to 45
• Arizona at UCF was bet up from 54 to 55 points

Midweek College Football Week 10 Odds Rundown

Midweek Betting Movement

• New Mexico State took plenty of action, being bet down from +10 to +7.5
• Texas State was bet off a key figure of -3 to -4
• UConn moved from -5.5 at open to -7
• Tulane at Charlotte moved off a key totals number, bet up from 55 to 56 points

Midweek Betting Notes

• New Mexico State comes in off a bye week, while FIU comes off three consecutive losses
• Four of FIU's last five games finished within a score; the fifth finished with a nine-point differential — that includes a loss to FCS Monmouth
• Sonny Cumbie is 6-14 ATS against Conference USA competition at Louisiana Tech. Cumbie is also 1-15 outright on the road, including 0-3 this year
• Liberty (-27.5) lost outright to Kennesaw State, moving to 1-5 ATS on the year and 0-6 ATS in the first half
• WKU is 6-1 ATS this year, one of just seven teams with that mark or better
• Watch for a major letdown spot with Kennesaw State, coming off its huge upset win over Liberty and facing a WKU home team off a bye
• Georgia State is the final home opponent for UConn of a seven-week home stand (six games and a bye)
• Last year, FAU (+2) crushed USF, 56-14, notching its first FBS win against an in-state foe
• Boise State has been favored over San Diego State in eight of nine meetings, and the underdog has won outright five times

Coaching & Matchup Notes for College Football Week 10 odds

Louisiana at Texas State, Tuesday (7:30 p.m., ESPN2)

• The Ragin' Cajuns are 10-1 ATS against Texas State as Sun Belt opponents (11-0 straight up!)
• Between Sept. 28 and Nov. 16, every opponent but one (App State) for Louisiana either comes off a bye or is played on the road
• Despite a 6-1 record, Louisiana is just 3-4 ATS this season
• All three of Texas State's losses this year came as favorites (-2.5 vs. Arizona State, -10.5 vs. Sam Houston, -10.5 vs. Old Dominion)
• Watch for rain and wind in this game!

No. 4 Ohio State at No. 3 Penn State, Saturday (12 p.m., FOX)

• Ohio State leads the all-time series 24-14, including winning each of the last seven meetings
• Since 2012, Penn State has won this rivalry once — the infamous 2016 "Block Six" upset of No. 2 Ohio State
• A top-three team has not been a home underdog to a lower-ranked foe since at least 2017
• The Buckeyes lost multiple starting offensive linemen to injury and did not run the ball effectively last week against Nebraska
• Penn State QB Drew Allar exited last week's win at Wisconsin and did not return
• Due to TV rights, this game will again be played at noon, rather than be Penn State's Whiteout feature

Check out the full rundown of Ohio State at Penn State odds here

Air Force vs. No. 21 Army, Saturday (12 p.m., CBS)

• Air Force leads the all-time series 38-19-1
• Falcons are the lone winless FBS team against the spread (0-7). Troy Calhoun entered 2024 with a 60% ATS cover rate as a head coach
• Army is the lone FBS team undefeated against the spread (6-0-1)
• Last year, Army won the Commander-in-Chief's trophy thanks to a shocking upset of Air Force as a +17 underdog
• Army won three of the last four meetings, all as an underdog, and five of the last seven (four times as an underdog)
• The last 10 meetings between these teams averaged 28 combined points
• An Army win here cements December's Army-Navy Game as a winner-take-all contest for the Commander-in-Chief's trophy

Duke at No. 5 Miami (FL), Saturday (12 p.m., ABC)

• Miami leads the series 15-5. Three of Duke's wins came in the last five meetings
• Manny Diaz was relieved of the Miami head coaching position after the 2021 season and returns as Duke's head coach to face his former team for the first time
• The Hurricanes are 1-3 ATS against ACC opponents, although last week's 22-point margin against Florida State was just shy of a -22.5/-23 closing line
• Miami last started 8-0 in 2017 before losing its final three games, including both the ACC championship game and Orange Bowl
• Seven of Duke's eight games this year did not feature a team scoring 30 points
• The Blue Devils played one top-50 opponent, per aggregate power ratings — that being SMU, which beat them in overtime last week, 28-27

Texas Tech at No. 11 Iowa State, Saturday (3:30 p.m., ESPN)

• Texas Tech leads the all-time series, 11-8
• Tech won the last two meetings — both times as an underdog — snapping a five-game losing skid to Iowa State
• Coming off its bye, Tech lost two straight games to Baylor and TCU and allowed 94 points in the games
• Joey McGuire is 4-10 straight up on the road with Tech, including 1-2 this year
• Iowa State comes off a bye as one of six remaining unbeaten FBS teams (6-0)

Florida vs. No. 2 Georgia, Saturday (3:30 p.m., ABC)

• Florida leads the "World's Largest Outdoor Cocktail Party," 55-44-2
• Game is played at TIAA Bank Field in Jacksonville, Florida, and has been played in the city since 1933
• Both teams come off a bye, as is tradition with this rivalry
• Due to lofty preseason expectations, Georgia is just 2-5 ATS this year — its two covers came at No. 1 Texas and against No. 14 Clemson
• Florida covered its last four games, winning three of those games outright, despite losing starting QB Graham Mertz to a torn ACL
• RB Jadan Baugh scored five touchdowns in a 48-20 dismantling of Kentucky

No. 1 Oregon at Michigan, Saturday (3:30 p.m., CBS)

• Michigan leads the all-time series 3-2, but the two have not played since 2007 (just two meetings since 1973). Oregon won in 2007 and 2003
• The Wolverines went back to a Davis Warren/Alex Orji split at QB, moving away from Jack Tuttle. Orji did not attempt a pass against Michigan State (but RB Donovan Edwards did!)
• After a 1-3 ATS start for Oregon, the Ducks covered three straight, including beating Purdue and ranked Illinois by a combined 73-9
• Oregon allowed one 100-yard rusher this year, Ashton Jeanty (25-192-3), in Week 2
• Dan Lanning is 23-12 ATS as head coach at Oregon

Wisconsin at Iowa, Saturday (7:30 p.m., NBC)

• Battle for the Heartland Trophy!
• Wisconsin leads the all-time series 49-46-2, but Iowa has won three of the last four
• Iowa RB Kaleb Johnson has only failed to rush for 100 once, in Week 6 against Ohio State (81 yards)
• Since losing starting QB Tyler Van Dyke to a season-ending injury, Wisconsin is 3-2 outright
• The Badgers are 0-3 against teams inside the top 35, according to aggregate power ratings, with an average MOV of -21.3 points (5-0, +25.8 MOV against all others). Iowa ranks 25th heading into Week 10

Louisville at No. 11 Clemson, Saturday (7:30 p.m., ESPN)

• Clemson leads the all-time series 8-0, with all of those meetings coming in the last 10 years (6-2 ATS)
• Jeff Brohm has never coached against Dabo Swinney (28 combined years of coaching between the two)
• Since being held to 3 points in Week 1 against Georgia, Clemson has scored 40+ five times and never failed to hit 28
• Two weeks ago, Miami became the first team to score 35 on Louisville all season (52 points)
• Since cracking the Top 20 with a 31-19 win over Georgia Tech, the Cardinals are 0-4-1 ATS with three outright losses

Kentucky at No. 7 Tennessee, Saturday (7:45 p.m., SEC Network)

• Tennessee dominates this series, 84-26-9, including a 26-game winning streak between 1985 and 2010
• The Vols come off a bye week
• Against SEC competition, Tennessee has not scored 28 points (63.7 ppg against non-conference foes)
• In its win over Alabama, Tennessee was flagged 11 times for 95 yards. The Vols are the 11th-most flagged team in the FBS
• Since upsetting No. 6 Ole Miss on the road, Kentucky is 0-3 — all three times as a favorite — with a 28-point loss to Florida and a 14-point loss to Auburn
• Kentucky is just 5-14 ATS in Knoxville since 1986! The last time out, in 2022, UK (+11) suffered a 44-6 loss

No. 18 Pitt at No. 20 SMU, Saturday (8 p.m., ACC Network)

• SMU leads the all-time series 3-2, with the last meeting coming in the 2012 Compass Bowl
• The previous meeting came in the 1983 Cotton Bowl, played between the Pony Express SMU team and future NFL Hall of Famer Dan Marino. SMU won, 7-3
• In two meetings against Pitt as the offensive coordinator at Miami, Rhett Lashlee scored 69 points (821 yards)
• Since heading on bye in Week 4 (and coming off a loss to BYU), SMU won five straight, scoring 42 points per game
• Pitt is 6-1 ATS this season, only failing to cover against Cal, and is one of six remaining undefeated FBS teams (7-0)

Impact Injuries On College Football Week 10 Odds

All kick times below are listed in ET.

No. 4 Ohio State at No. 3 Penn State, Saturday (12 p.m., FOX)

Starting QB Drew Allar exited Penn State's 28-13 win at Wisconsin and did not return. Backup Beau Pribula completed 11-of-13 passes for 98 yards and a score. He also rushed six times for 28 yards. Pribula presents more of a rushing threat than Allar, resembling an offense under Trace McSorley in recent Penn State history. Despite excitement around OC Andy Kotelnicki, Penn State is scoring just 26.5 points in regulation against Big Ten competition.

Ohio State's injuries are immediately evident. Left tackle Josh Simmons is done for the season, and backup Zen Michalski left last week's win over Nebraska. All-American guard Donovan Jackson moved out to left tackle, putting in a backup in his spot. The Buckeyes were unable to run the football with the line shuffle, and it is worth consideration against a disruptive Penn State defensive front. Starting safety Lathan Ransom also missed Week 9.

Stanford at NC State, Saturday (12 p.m., ACC Network)

NC State starting QB Grayson McCall announced his retirement from football last week following a serious concussion. McCall threw for over 10,000 yards and 91 touchdowns in his decorated career at Coastal Carolina and NC State. Starting running back Jordan Waters missed the Wolfpack's last game in Week 8 but did have a bye week to recover and return.

No. 1 Oregon at Michigan, Saturday (3:30 p.m., CBS)

Michigan was without All-American corner Will Johnson last week, although there's optimism the injury isn't long-term. All-American candidate safety Rod Moore suffered a season-ending injury in the spring, thinning Michigan's secondary further. The Wolverines also placed QB Jack Tuttle on the injury report despite a report that he'd be benched anyway.

Oregon tight end Terrence Ferguson missed a second game after having his appendix removed before the Ducks' Week 8 game at Purdue. His status is uncertain for Saturday. Top defender Jordan Burch missed his third game after being declared out before Oregon's Week 7 game against Ohio State.

UCLA at Nebraska, Saturday (3:30 p.m., ABC)

Nebraska continues to deal with widespread injuries to the roster. Tackle Turner Corcoran, who was already in relief of injured Teddy Prochazka, traveled with the team the last two weeks but hasn't seen the field. Starting running back Ramir Johnson missed last week against Ohio State, and kicker Tristan Alvano hasn't played since Week 3. Though he did not miss any snaps, QB Dylan Raiola was "potentially injured," per a report, in Week 9.

Top UCLA receiver Rico Flores continues to progress toward a return. He hasn't played since Week 5 but has taken part in practice and warmups the last two weeks. UCLA comes off a bye. Starting defensive tackle Keanu Williams has not played since Week 3.

Arizona State at Oklahoma State, Saturday (7 p.m., FS1)

Arizona State QB Sam Leavitt missed the Sun Devils' last game with a rib injury. Uncertainty pours from the ASU coaching staff about his availability. Kenny Dillingham said Leavitt could return for this game, or he could miss several more games. The QB was evaluated and had a bye week to recover.

Oklahoma State is missing several key pieces. QB Garret Rangel, who replaced Alan Bowman, is out for awhile with what could be an injury that ends his season. The Pokes' top defender, linebacker Collin Oliver, remains out, likely for the year. Starting offensive tackle Dalton Cooper, linebacker Nickolas Martin, and running back Ollie Gordon all sat out in Week 9. Gordon has been largely ineffective after rushing for over 1,700 yards and 21 touchdowns last season. Oklahoma State is off to a rough 0-5 start in Big 12 play.

Other Impact Injuries

• Ja'Quinden Jackson, RB, Arkansas
• Omari Hayes, WR, FAU
• Montrell Johnson, RB, Florida
• Tate Ratledge, OG, Georgia
• Pat Bryant, WR, Illinois
• Kurtis Rourke, QB, Indiana
• Beau Stephens, OG, Iowa
• Chip Trayanum, RB, Kentucky
• Donerio Davenport, RB, Louisiana Tech
• Frank Peasant, RB, Middle Tennessee
• Kelly Akharayi, WR, Mississippi State
• Brendon Lewis, QB, Nevada
• Luke Wysong, WR, New Mexico
• Grant Wilson, QB, Old Dominion
• Tre Harris, WR, Ole Miss
• Walter Nolen, DL, Ole Miss
• Eli Holstein, QB, Pitt
• Hunter Watson, QB, Sam Houston State
• Noah Smith, WR, Sam Houston State
• Oronde Gadsden, TE, Syracuse
• Chase Bisontis, OL, Texas A&M
• Behren Morton, QB, Texas Tech
• Jacob Zeno, QB, UAB
• Eric Gentry, LB, USC
• Byrum Brown, QB, USF
• Garrett Greene, QB, West Virginia
• Wyatt Milum, LT, West Virginia
• Jalen Royals, WR, Utah State (season)

Other Roster & Staff Impacts on College Football Week 10 Odds

Tulane at Charlotte, Thursday (7:30 p.m., ESPN)

QB Max Brown was benched in favor of Deshawn Purdie last week. Brown finished the first half 4-for-8 passing with an interception, and Charlotte scored just seven points. Under Purdie, the 49ers scored 21 fourth-quarter points, though Purdie completed just 5-of-14 passes.

Arizona at UCF, Saturday (3:30 p.m., FS1)

Gus Malzahn is relinquishing play-calling duties to offensive coordinator Tim Harris Jr. this weekend. UCF struggled offensively in two of its last three games, scoring 24 against BYU, 13 against Cincinnati, and 13 against Florida. After starting 3-0, UCF lost five straight and the tenure of Malzahn may be in question. Since joining the Big 12, UCF hasn't won more than seven games, going 6-7 last year and already owning a 3-5 record this season. With Arizona, Arizona State, West Virginia, and Utah on deck, UCF cannot drop two games, or it will miss a bowl game for the first time since 2015.

No. 1 Oregon at Michigan, Saturday (3:30 p.m., CBS)

Michigan went back to a rotation between QBs Davis Warren and Alex Orji. Orji did not attempt a pass but rushed six times for 64 yards and a touchdown. Warren completed 13 of his 19 passes for 123 yards and a touchdown against Michigan State. Running back Donovan Edwards also attempted a pass. QB Jack Tuttle went back on the injury report, though Warren was already expected to start.

Navy at Rice, Saturday (4 p.m., ESPN2)

Rice fired head coach Mike Bloomgren after a 2-6 start to the year. Bloomgren led Rice to their first two bowl games in a decade, the second with enough wins, but started just 8-13 after the move to the American. Special teams coordinator Pete Alamar will lead the Owls in the interim.

Wyoming at New Mexico, Saturday (4 p.m., truTV/MAX)

Wyoming running back Harrison Waylee took a redshirt this season but is eligible to play the Cowboys' final three games after playing just one in the first nine weeks. Waylee had back-to-back 800+ yard rushing seasons and has over 2,700 yards in his career in Laramie. Wyoming ranks 125th in rush EPA this year (132nd in total offense EPA), while New Mexico is 128th against the run.

No. 10 Texas A&M at South Carolina, Saturday (7:30 p.m., ABC)

Backup QB Marcel Reed replaced a struggling Conner Weigman last week and led Texas A&M to a 38-23 win over rival LSU. Reed came into the game in the third quarter, down 17-7, and scored 31 points in five drives — all of which ended in a score (four straight touchdowns, ended on a field goal).

Wisconsin at Iowa, Saturday (7:30 p.m., NBC)

Iowa benched Cade McNamara after three drives against Northwestern, the final one ending in a pick-six. Brendan Sullivan stepped in and led the Hawkeyes to 24 points in two quarters (Iowa also scored on two punt return touchdowns). Given the spark to the offense, expect Sullivan to be QB1 heading into Week 10.

TCU at Baylor, Saturday (8 p.m., ESPN2)

Running back Trent Battle started over Cam Cook against Texas Tech. Battle rushed for just 10 yards on seven attempts. Receiver Savion Williams was the team's leading rusher, carrying the ball 11 times for 72 yards and a score. Williams lined up frequently as a wildcat quarterback, his touchdown coming on a dazzling run where he broke multiple tackles. Expect TCU to return to the wildcat moving forward, given its success.

However, beware of tape on the wrinkle being out and teams game planning against it.

For Week 11: Oregon State benched QB Gevani McCoy in favor of Ben Gulbranson. Without Hudson Card, Georgia Tech benched backup Zach Pryon against Virginia Tech for Aaron Philo. The Jackets' QB situation is dire without Card.

Weather Impacts On College Football Week 10 Odds

Weekly college football weather reports will be released later this week as forecasts become more certain. But here’s a few spots to keep tabs on early in the week.

As cold temperatures transition across the U.S., expect a more active weather pattern in November. Louisiana at Texas State may be the first to see impacts, with rain and wind expected Tuesday. Should the forecast shift up, San Marcos could see thunderstorms.

San Diego State at Boise State could see not just rain, but near-freezing temperatures – a real issue for San Diego State. Georgia State at UConn is forecast to see rain, potential wind, and cold temperatures Friday as well. Colorado State at Nevada could also see temperatures crossing freezing during the game on Saturday.

Keep an eye on windy conditions across the U.S. as cold temperatures blow in this fall.

Situational Spots To Watch With College Football Week 10 Odds

Stanford at NC State, Saturday (12 p.m., ACC Network)

Stanford flies back across the country to play at noon Eastern or, more importantly, 9 a.m. PT. Clocks fall backward this weekend, but not until after this game completes. But watch for a body clock game here – college athletes are much more affected by weird time games than professionals, who travel across time zones regularly. For the most recent example of a body clock game, see Arizona State's sluggish output at Cincinnati, which was also played at 9 a.m. internally across three time zones.

As new alignment sets in for seasons ahead, perhaps these impacts will lessen. But for first-year athletes, this is a major issue for Stanford.

Virginia Tech at Syracuse, Saturday (12 p.m., The CW)

Virginia Tech successfully regrouped after a rough start to the season and put itself back in the ACC race. The most pivotal game for the Hokies sits on deck, a game in Lane Stadium against Clemson. But to get there, Virginia Tech has to travel to Syracuse and face a team that just threw three pick-sixes against Pitt. Virginia Tech is spotted just a few points for the occasion. Weirder things have happened at the JMA Wireless Dome.

No. 19 Ole Miss at Arkansas, Saturday (12 p.m., ESPN)

Coming off a win at Oklahoma, Ole Miss hits the road to play Arkansas with a major matchup in the window: Georgia. We've had some bizarre Ole Miss-Arkansas matchups in the recent past, with last year's game coming down to a 10-point fourth quarter for the Rebels to win at home. Three years ago, we had the wild 52-51 shootout. Besides a 33-10 loss to LSU, Arkansas has been playing good, competitive football.

Ole Miss opened a -6.5 favorite on the road and didn't budge to -7.

Duke at No. 5 Miami (FL), Saturday (12 p.m., ABC)

This is the first game where ex-Hurricane head coach Manny Diaz gets a shot at his old team. Duke sits 5-2 with a tough overtime loss to SMU. Miami has a game at Georgia Tech next week. That's normally not a lookahead spot, but given last year's fiasco, Cristobal – not known to be a tactician – likely has that one circled. It's an easy lookahead position for Miami against a team with a pesky defense being spotted nearly three full touchdowns. A noon atmosphere at Hard Rock is questionable, as well (for threat of ending up on Freezing Cold Takes).

UCLA at Nebraska, Saturday (3:30 p.m., Big Ten Network)

We have multiple factors working against each other in this one. First, Nebraska returns home beat up with a chance to have upset Ohio State on the road. QB Dylan Raiola could have been injured (the report was "possible injury") and the Huskers are missing multiple linemen. UCLA presents the third straight foe coming off a bye week that Nebraska faces, the second straight at a rest disadvantage.

On the other end, you have the observable issue with conference realignment and long-distance travel. While this doesn't present a body clock game for UCLA, the distance traveled has been an issue. Before the bye week, the Bruins traveled over 10,800 miles in a five-week stretch. Now, back to the road for Lincoln.

North Carolina at Florida State, Saturday (3:30 p.m., ACC Network)

Coming off a straight-up loss, Mike Norvell-led FSU is an astounding 5-16 ATS. The 'Noles barely covered off a loss for the first time this year, losing by 22 points to Miami (FL) as +22.5/+23 underdogs. The bottom line: this team just doesn't collect itself off a loss well.

North Carolina comes to town with FSU already eliminated from the postseason. UNC sits 4-4 and is a short favorite. The Tar Heels are also sandwiched between games at Miami and Notre Dame. Regardless of where Florida State sits, those games are circled on calendars. UNC heads into a bye after the game.

No. 17 Kansas State at Houston, Saturday (3:30 p.m., FOX)

Kansas State has a history of underperforming on the road (see: BYU earlier), especially in spots where the Wildcats are heavily favored to win. Houston was demolished by Kansas just two weeks ago, but bit both TCU and Utah in recent outings. The Cougars defense remains solid (aside from that KU blowout) and is a unit that excels in havoc. Avery Johnson buckles quickly against chaotic defenses and is mistake-prone at times. This is a game that could get away from him early on.

Hawaii at Fresno State, Saturday (7 p.m., N/A)

The nightmare travel stretch for Hawaii continues. While the Rainbow Warriors are no strangers to long road trips, they alternate home and away tilts every weekend from Week 6-12. Hawaii is 0-3 in its last three road games and 1-3 in its last four games overall (since starting the home/road split).

No. 10 Texas A&M at South Carolina, Saturday (7:30 p.m., ABC)

Texas A&M comes off a big win over rival LSU where backup Marcel Reed came in and injected life into the offense. Do they have that in the bag again? Or will A&M continue to roll the dice with a QB competition? This is a prime letdown spot for a team currently on a roll.

This isn't the first time South Carolina finds itself as the letdown spot — they took Alabama down to the wire, ultimately losing 27-25, after the Tide beat Georgia. The Gamecocks thumped Oklahoma coming off its big rivalry with Texas. With a defensive front as talented as South Carolina — and with talented, if not inconsistent, offensive pieces — this could be a spot to watch this Saturday.

Best of luck betting college football Week 10 odds!