College Football Conference Championship Week Best Bets, Odds, Picks & Player Props

Written By Nick Crain | Published at December 6, 2025
Ohio State Buckeyes quarterback Julian Sayin (10) looks to pass during the NCAA football game against the Michigan Wolverines at Michigan Stadium in Ann Arbor, Mich. on Nov. 29, 2025. Ohio State won 27-9.

Conference Championship Week gives teams one final chance to shape their College Football Playoff résumé. It’s also one of the best betting days of the season with four primary high-stakes matchups on the board.

Below are our favorite college football best bets for today across sports betting apps and sportsbook promotions — including four game lines, four player props and a three-leg parlay.

Game Lines

BYU +12.5 (-105) vs Texas Tech

🏈Odds via Caesars Sportsbook📈

Texas Tech beat BYU earlier in the season, but the score was more lopsided than the flow of the game. The Cougars' defense matched up better than expected and their offense has trended upward late in the year. Getting nearly two touchdowns in a neutral title-game environment gives BYU enough margin to stay inside this number.

Georgia ML (-125) vs Alabama

🏈Odds via BetMGM📈

Alabama’s offense is explosive with quarterback Ty Simpson and star receiver Ryan Williams, but Georgia’s defense is built to limit big plays and force long drives. The Bulldogs are the more balanced team on both lines, and laying a short moneyline price removes late-game spread variance.

Virginia -4.5 (-105) vs Duke

🏈Odds via bet365📈

Duke can score in a variety of ways, but the defense has slipped materially down the stretch. Virginia’s passing game should find success against Duke’s secondary, and the Cavaliers have the more reliable defense in a championship setting. Laying fewer than a touchdown is reasonable.

Ohio State -4 (-109) vs Indiana

🏈Odds via BetMGM📈

Indiana’s offense is legit with Fernando Mendoza, but Ohio State’s defense is on another tier and has been dominant wire to wire. Julian Sayin spreads the ball to Jeremiah Smith, plus the offense features Bo Jackson and a deep skill group, giving the Buckeyes clear edges on both sides. A short number pairs well with their matchup advantages.

Player Props

Cameron Dickey over 86.5 rushing yards (-115)

🏈Odds via bet365📈

Dickey has been Texas Tech’s workhorse and already surpassed 1,000 yards on the ground. He went over 120 yards in the first meeting with BYU and should again see heavy volume in a game where Tech leans on its run game.

Ryan Williams over 42.5 receiving yards (-115)

🏈Oddsvia Caesars Sportsbook📈

Williams is Alabama’s top vertical threat and one of the most explosive young receivers in the country. Even against a strong Georgia defense, his target share and big-play ability give him multiple paths to clearing this number.

Sahmir Hagans over 2.5 receptions (-110)

🏈Odds via BetMGM📈

Duke manufactures touches for Hagans in key situations and he averages just under three catches per game. Against Virginia, Duke is likely to throw more often, making three receptions very attainable.

Fernando Mendoza over 206.5 passing yards (-113)

🏈Odds via bet365📈

Mendoza has been one of the breakout quarterbacks of the season and regularly clears this yardage number in competitive games. Even if Ohio State’s defense is elite, the game script should push Indiana into a pass-heavy approach.

Player Props Parlay

🏈Combined Parlay Odds: +425 (via BetMGM)📈

This three-leg parlay features Ohio State’s star receiver, who is Sayin’s top option and a red-zone staple, Texas Tech’s featured back with consistent goal-line usage, and a back with nearly 1,000 rushing yards for the Buckeyes. Combining the lead red-zone threats from two of the day’s highest-powered offenses creates a correlated and high-floor parlay with upside.

Conference Championship Week is the final showcase before bowl season and the playoff announcement. Whether you’re backing game lines, rolling with the player props or building out parlays, check sports betting apps for the best available numbers and sportsbook promotions.

All Odds as of 6:00 a.m. ET on Dec. 6