Syracuse vs. Indiana Prediction, Odds & Picks for Nov. 9: Markus Burton Leads the Hoosiers
The Syracuse Orange face off against the Indiana Hoosiers in a neutral-site matchup at Gainbridge Fieldhouse in Indianapolis, Ind. Although it’s technically a neutral-site game, this is essentially a home matchup for the Hoosiers. Our Syracuse vs. Indiana prediction covers odds, betting trends, and best bets for Monday’s college basketball matchup.
The Orange are 2-0 after convincing wins over Central Connecticut and New Haven in their first two games. They’ve beaten each team comfortably and haven’t had any early-season trouble.
The Hoosiers are also 2-0, with wins over Eastern Illinois and Bellarmine. Similarly, they haven’t faced any early-season adversity.
Syracuse vs. Indiana Odds
The Orange and Hoosiers both have NCAA Tournament aspirations, and this would be a solid win for either team. It’s a slightly bigger opportunity for Syracuse, though. Indiana is the neutral-site favorite via DraftKings Sportsbook:
- Spread: Syracuse +5.5 (-115) / Indiana -5.5 (-105)
- Moneyline: Syracuse (+190) / Indiana (-230)
- Total: Over 147.5 (-112) / Under 147.5 (-108)
The oddsmakers expect a fairly high-scoring game, with the Hoosiers at a 69.7% implied win probability, according to our Probability Calculator.
Check the latest odds before betting, as lines tend to shift throughout the week.
New DraftKings Customers: Bet $5, Get $200 + 3 Months of NBA League Pass Syracuse Orange Betting Trends
With a new head coach, Syracuse lost the majority of their roster, but they did return two key pieces in Kiyan Anthony and Sadiq White. They also brought in Gavin Doty, Aiden Tobiason, Garwey Dual, and Luke Wilson via the transfer portal. Mark Morano and Ryan Moesch look to play key roles as freshmen. Here are some trends for Syracuse:
- The Orange are 2-0 straight up and 1-1 ATS this season.
- The Over is 2-0 in Syracuse games in 2026-27.
- The Orange posted over 100 points in their last game.
- Syracuse held both opponents to only 107 combined points.
Syracuse has blown out both of its opponents this season, but Doty’s still played 75% of the minutes. Anthony and Morano have been the two focal points of the offense, as they both have shot rates over 30%. White also boasts a high-end scoring role, particularly because of his ability to draw fouls. Moesch is quietly acting as a high-quality facilitator while on the floor.
The Orange have played fairly safe basketball early in the 2026-27 season. They aren’t creating non-steal turnovers, but they also aren’t turning the ball over themselves. The major issue for this offense has been their shooting, specifically from deep and at the line.
Indiana Hoosiers Betting Trends
The majority of the Hoosiers team graduated, but Sam Alexis and Trent Sisley returned for another season. They reloaded their rotation in the transfer portal, adding Markus Burton, Darren Harris, Jaeden Mustaf, Aiden Sherrell, Samet Yigitoglu, and Bryce Lindsay. They also added freshman Trevor Manhertz, who figures to have a role. Here are some trends for Indiana:
- The Hoosiers are 2-0 straight up and 0-2 ATS this season.
- The Over is 2-0 in Indiana games in 2026-27.
- The Hoosiers have scored over 90 points in both games.
- Indiana has won both games by more than 20 points.
Burton runs the offense, posting an assist rate over 30% early on. Harris and Lindsay own shot rates over 30%, although this team has several offensive options who can take over. Sherrell, Yigitoglu, Alexis, and Sisley combine to make up one of the deepest frontcourts in college basketball.
Indiana’s performed extremely well in nearly every facet of the game against weaker competition. Eastern Illinois shot 61.1% on two-pointers, while Bellarmine shot 55.9% inside the arc. Neither opponent found a ton of overall success, but it’s a key to keep an eye on when the competition gets better.
Syracuse vs. Indiana Prediction: Markus Burton Over 21.5 PRA
Markus Burton over 21.5 points, rebounds, and assists is my favorite Syracuse vs. Indiana prediction.
Burton only played 10 games for Notre Dame last season, and he was generally viewed as a disappointment for what people thought he’d be. In those games, he still averaged 18.5 points, 2.8 rebounds, and 3.7 assists in 30.0 minutes per game.
This was generally viewed as a step back because he was significantly better as a sophomore at Notre Dame. Still, he was dealing with injuries in limited games.
Burton transferred to Indiana, and he won’t have as big of a role as he did with Notre Dame. He’s averaging 10.5 points, 2.0 rebounds, and 4.5 assists in only 24.5 minutes per game thus far.
We’ve seen Indiana in two blowout wins, and I expect more of this offense to run through Burton in their first real game of the season.
Best Bet: Markus Burton Over 21.5 PRA (-130 @ DraftKings Sportsbook)
More Syracuse vs. Indiana Picks, Props and Best Bets
Here are a few more Syracuse vs. Indiana betting angles to consider:
- Indiana -5.5 Spread (-105 @ DraftKings Sportsbook) - This is essentially a home game for the Hoosiers. I trust their depth more if anyone gets into foul trouble, specifically in the front court.
- Syracuse/Indiana Over 147.5 Points (-112 @ DraftKings Sportsbook) - These are two teams that have been undervalued on the total so far this season, and Indiana will look to turn this game into a track meet.
- Darren Harris Over 9.5 Points (-120 @ DraftKings Sportsbook) - Harris is a streaky shooter, so there’s always some volatility involved with a player like him. He owns a shot rate north of 25% through two games, though, and the volume will be there, especially if his shot is falling early.
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170,000 GC + 7 SC Syracuse vs. Indiana Broadcast Info
- Date: Monday, Nov. 9, 2026
- Start time: 6:30 p.m. ET
- Location: Gainbridge Fieldhouse, Indianapolis, Ind.
- TV and streaming: Fox Sports 1
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